Thank you for the summary, Nancy. I am so disappointed that I had to miss 
it!

----- Original Message ----- 
From: [email protected]
To: [email protected]
Sent: Wednesday, February 04, 2009 6:58 AM
Subject: Re: DNA in action!



Last night's R-Spec meeting was fascinating -- it was too bad that only 
seven people could make it.  Mark Zahn, Alicia's boss, spoke about 
Biodefense.  He slanted his talk toward practical knowledge for SF writers 
who want to include weaponized genemods in their stories, and he did a 
wonderful job.

He talked about which pathogens best lend themselves to modification (Ebola, 
for instance, has a very small genome and produces only eight proteins, 
which means there's just not room enough in the cell to fit a lot of extra, 
genetically engineered stuff.)  Mark covered the assembly of viruses using 
sequencing data and "off-the-shelf" sections of DNA.  He talked about the 
origins and spread of epidemics.  I hadn't known that the natural host for 
influenza was an Asian species of duck, and that the way vaccine makers 
guess at which strains of flu will hit in a given winter is by examining 
ducks in late summer.

The talk also covered what you need for a rogue genemod lab to weaponize 
pathogens: off-the-rack equipment, experienced talent, and no more than a 
few million dollars.  What the Russians may or may not have been doing in 
this regard was discussed, including a recommendation for Ken Alibek's scary 
book BIOHAZARD (which I have read -- it's horrifying).  Mark finished with 
an overview of surveillance techniques used to spot and track epidemics so 
that appropriate measures can be taken, including quarantine if necessary.

Thank you, Alicia.  It was terrific.



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