Years ago I ran a UHF repeater on 444.300, and a packet digipeater on 145.01. I used a Comet dual-band omni up about 350'.
I experienced no problem at all. The UHF repeater duplexer was fed into one side of one of those little diplexer things, and the packet system into the other port. Sam Nelson Kay Communications, Inc. (337) 625-3690