We have a web-application in DMZ sending messages to our backend using 
Bus.Send().
The application subscribes to several messages from the backend using 
Bus.Notify().

The above two scenarios works, but for 2 messagetypes we use send/reply and 
they doesn't work in prod environment.

Both msmq instances for the bus hosts are installed with only "Message 
Queuing Server" feature.


We get this in the Event Viewer:

Message Queuing could not access Active Directory Domain Services and 
failed to compute routing path
 for messages sent to queue 3fe8c734-de40-4761-8902-9bd1f2f191e1\00000010. 
Messages will wait in the
 outgoing queue until connection with Active Directory Domain Services is 
restored.  This event is
 logged at most once per 600 seconds. To change this setting, set 
\HKLM\Software\Microsoft\MSMQ\Parameters\Event2188
 registry value to desired time in seconds. Error 0xc00e006a:


Everything works when we route the DMZ application through another backend 
with the same setup. Except that the working backend is using a normal user 
domain account as the application context, and the failing backend is using 
a service domain account. My guess is that the service account lack some 
vital permissions I just can't figure out what and I need to be very 
explicit when communicating with sysop.

HELP!

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