Zabbix is a monitoring system similar to Nagios. When I saw there was a Nagios extension to automatically close tickets it generated, I decided to write the same thing for Zabbix. It's based on RT-Extension-Nagios, so someone else already did all the hard work.
If anyone else uses Zabbix and is interested in it, you can find it at https://github.com/grantemsley/rt-extension-zabbix