While I can access the cram file using samtools view, samtools idxstats doesn't 
work on cram files.  It ran but reported 0 for all stats apart from 
chromosome/contig length (a few lines below).  This must be some problem of 
samtools accessing cram's reference registry.

>samtools idxstats 
>ftp://ftp.1000genomes.ebi.ac.uk/vol1/ftp/hgsv_sv_discovery/data/HG00732/high_cov_alignment/HG00732.alt_bwamem_GRCh38DH.20150715.PUR.high_coverage.cram
> | less
chr1    248956422       0       0
chr2    242193529       0       0
chr3    198295559       0       0
chr4    190214555       0       0
chr5    181538259       0       0
chr6    170805979       0       0

Has anyone run into this issue before?

Best.

Holly

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