[ccp4bb] Deadline Thursday June 18: Facility Manager for CPHSAXS at Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen Denmark

2020-06-16 Thread Michael Gajhede



We are looking for a highly motivated and independent academic research staff 
for a position as facility manager for a new In-House bioSAXS facility CPHSAXS 
funded by the Novo Nordisk Foundation. The position is available from August 1 
2020 or as soon as possible thereafter until the end of 2024.

Our research
The facility is established in a group of collaborators; Michael Gajhede and 
Annette Eva Langkilde (Dept. Drug Design and Pharmacology), Vito Foderà and 
Martin Malmsteen (Dept. of Pharmacy), Lise Arleth (Niels Bohr Institute) and 
Søren Skou (SAXSLAB/Xenocs); with research projects covering discovery, 
formulation and delivery of biopharmaceutics, amyloid research, enzymatic 
catalysis, membrane proteins, disordered systems and colloid research, as well 
as technological and methodological developments within the use of solution 
scattering.

In addition to the core collaborators, the facility will be open to a broader 
user community, facilitating the use of SAXS in a range interdisciplinary 
research projects in the region. The facility will be located at the Department 
of Drug Design within the Peptides and Proteins discipline.

Your job
The tasks includes attracting and training of new users, advising on e.g. 
sample preparation and requirements, support with data collection and 
assistance with data analysis on collaborative projects. Your tasks will also 
include setting up and managing the scheduling/access platform, user accounts, 
and providing material for annual reports on the use and outcomes, organize 
annual user meetings and contribute to training courses, and represent the 
facility. You will be responsible for the daily maintenance of the instrument 
and, in collaboration with SAXSLAB/Xenocs, contribute to continued 
technological developments. You will have the opportunity to contribute to 
research projects primarily of the core collaborators but also the projects 
from a broader user community.

Profile
We are looking for a highly motivated and enthusiastic facility manager with 
solid technical knowledge and capabilities to build the frame and network 
around the facility. Specifically we are looking for the following competencies 
and experience:

Essential experience and skills

You have a PhD in structural biology, biophysics, biochemistry, or related.
Solid knowledge of SAXS data acquisition and analysis.
You have documented experience in SAXS for biologically relevant samples
You have an active interest in instrument and/or method development.
You have proven an ability to envision, plan and execute a research project
Service-minded with clear communication and networking  skills
Good English skills, written and spoken

Desirable experience and skills

Experience and knowledge with X-ray scattering hardware and/or programming
Knowledge of protein expression and purification is an advantage
Experience with DLS, HPLC and/or SEC-SAXS
Previous collaborations with industrial partners
Place of employment
The place of employment is at the Department of Drug Design and Pharmacology, 
University of Copenhagen. We offer creative and stimulating working conditions 
in dynamic and international research environment.

Terms of salary and employment
The employment as academic research staff with the title 'facility manager' 
(AC-TAP) is a full time and fixed-term position until 31 December 2024. 
Starting date is 1 August 2020 or after agreement. Employment will be in 
accordance with the provisions of the collective agreement between the Danish 
Ministry of Finance and AC (the Danish Confederation of Professional 
Associations). The monthly salary will be based on the number of years of work 
experience (seniority) with the possibility to negotiate a salary supplement 
based on prior experiences and qualifications. The employer will pay an 
additional 17.1 % to your pension fund.

Questions
For further information regarding the position, please contact Michael Gajhede; 
m...@sund.ku.dk<mailto:m...@sund.ku.dk> or Annette E Langkilde; 
annette.langki...@sund.ku.dk<mailto:annette.langki...@sund.ku.dk>.

Learn more:

Department of Drug Design and Pharmacology: https://drug.ku.dk/.

Integrative Structural Biology at UCPH: https://isbuc.ku.dk/.

Application
Your application should be in English and include:

Letter of application addressing the requirements (max. one page).
Curriculum Vitae (incl. two references)
A certified/signed copy of certificate(s) of education
Please submit your application by clicking on "Apply Now" below. Only online 
applications will be accepted.

Application deadline: 18 June 2020, 23.59 CET.

We reserve the right not to consider material received after the deadline, and 
not to consider applications that do not live up to the abovementioned 
requirements.

Interviews are expected to be held in week 25 and 26.

University of Copenhagen wish to reflect the diversity of society and welcome 
applications from all qualif

[ccp4bb] Deadline Thursday June 18: Facility Manager for CPHSAXS at Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen Denmark

2020-06-16 Thread Michael Gajhede
We are looking for a highly motivated and independent academic research staff 
for a position as facility manager for a new In-House bioSAXS facility CPHSAXS 
funded by the Novo Nordisk Foundation. The position is available from August 1 
2020 or as soon as possible thereafter until the end of 2024.

Our research
The facility is established in a group of collaborators; Michael Gajhede and 
Annette Eva Langkilde (Dept. Drug Design and Pharmacology), Vito Foderà and 
Martin Malmsteen (Dept. of Pharmacy), Lise Arleth (Niels Bohr Institute) and 
Søren Skou (SAXSLAB/Xenocs); with research projects covering discovery, 
formulation and delivery of biopharmaceutics, amyloid research, enzymatic 
catalysis, membrane proteins, disordered systems and colloid research, as well 
as technological and methodological developments within the use of solution 
scattering.

In addition to the core collaborators, the facility will be open to a broader 
user community, facilitating the use of SAXS in a range interdisciplinary 
research projects in the region. The facility will be located at the Department 
of Drug Design within the Peptides and Proteins discipline.

Your job
The tasks includes attracting and training of new users, advising on e.g. 
sample preparation and requirements, support with data collection and 
assistance with data analysis on collaborative projects. Your tasks will also 
include setting up and managing the scheduling/access platform, user accounts, 
and providing material for annual reports on the use and outcomes, organize 
annual user meetings and contribute to training courses, and represent the 
facility. You will be responsible for the daily maintenance of the instrument 
and, in collaboration with SAXSLAB/Xenocs, contribute to continued 
technological developments. You will have the opportunity to contribute to 
research projects primarily of the core collaborators but also the projects 
from a broader user community.

Profile
We are looking for a highly motivated and enthusiastic facility manager with 
solid technical knowledge and capabilities to build the frame and network 
around the facility. Specifically we are looking for the following competencies 
and experience:

Essential experience and skills

You have a PhD in structural biology, biophysics, biochemistry, or related.
Solid knowledge of SAXS data acquisition and analysis.
You have documented experience in SAXS for biologically relevant samples
You have an active interest in instrument and/or method development.
You have proven an ability to envision, plan and execute a research project
Service-minded with clear communication and networking  skills
Good English skills, written and spoken

Desirable experience and skills

Experience and knowledge with X-ray scattering hardware and/or programming
Knowledge of protein expression and purification is an advantage
Experience with DLS, HPLC and/or SEC-SAXS
Previous collaborations with industrial partners
Place of employment
The place of employment is at the Department of Drug Design and Pharmacology, 
University of Copenhagen. We offer creative and stimulating working conditions 
in dynamic and international research environment.

Terms of salary and employment
The employment as academic research staff with the title 'facility manager' 
(AC-TAP) is a full time and fixed-term position until 31 December 2024. 
Starting date is 1 August 2020 or after agreement. Employment will be in 
accordance with the provisions of the collective agreement between the Danish 
Ministry of Finance and AC (the Danish Confederation of Professional 
Associations). The monthly salary will be based on the number of years of work 
experience (seniority) with the possibility to negotiate a salary supplement 
based on prior experiences and qualifications. The employer will pay an 
additional 17.1 % to your pension fund.

Questions
For further information regarding the position, please contact Michael Gajhede; 
m...@sund.ku.dk or Annette E Langkilde; annette.langki...@sund.ku.dk.

Learn more:

Department of Drug Design and Pharmacology: https://drug.ku.dk/.

Integrative Structural Biology at UCPH: https://isbuc.ku.dk/.

Application
Your application should be in English and include:

Letter of application addressing the requirements (max. one page).
Curriculum Vitae (incl. two references)
A certified/signed copy of certificate(s) of education
Please submit your application by clicking on "Apply Now" below. Only online 
applications will be accepted.

Application deadline: 18 June 2020, 23.59 CET.

We reserve the right not to consider material received after the deadline, and 
not to consider applications that do not live up to the abovementioned 
requirements.

Interviews are expected to be held in week 25 and 26.

University of Copenhagen wish to reflect the diversity of society and welcome 
applications from all qualified candidates regardless of age, disability, 
gender, nationality, race, religion o

[ccp4bb] PhD fellowship at the Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen

2015-06-10 Thread Michael Gajhede
PhD fellowship in crystallography of G protein-coupled receptors

The Department of Drug Design and Pharmacology, Faculty of Health and Medical 
Sciences, University of Copenhagen is pleased to announce that a PhD fellowship 
will be available from Oct 1st 2105 or soon thereafter in discussion with 
strongest applicant. The application deadline is June 30th 2015.

Applications are invited for the three-year fellowship from applicants who hold 
or expect to hold a master´s degree in a relevant field. If the PhD project is 
successful, the employment can also be further extended with a two-year postdoc 
(already funded).


Project description
G protein-coupled receptors (GPCRs) form one of the largest human protein 
families and mediate the effect of 27% of current drugs. GPCR crystal 
structures are very valuable for understanding basic receptor structure and 
function, and as basis for rational drug design. Although still very 
challenging, technological breakthroughs have led to the determination of more 
than 110 GPCR crystal structures of 27 unique receptors. This project will 
reproduce an already crystallized receptor, the metabotropic glutamate receptor 
1 (mGlu1), transmembrane domain in complex with other ligands of interest to 
medicinal chemists at the Department. In parallel crystallization trials will 
be conducted for a new GPCR target.

The first half of the PhD studies will be in the labs of Raymond Stevens and 
Vadim Cherezov, that have produced the only published mGlu1 structure and the 
largest number of structures of any group worldwide, and located at the iHuman 
Institute in Shanghai, China. The second half of the PhD will be supervised by 
Professor Jette Sandholm Kastrup, who has an outstanding track record in 
structural biology studies of the ionotropic glutamate receptors, and Section 
Head Michael Gajhede, at the Department of Drug Design and Pharmacology, 
University of Copenhagen, Denmark. The project is part of a larger project on 
orphan GPCRs led by David Gloriam.

The PhD fellowship is financed by The Lundbeck Foundation and The Department of 
Drug Design and Pharmacology.

Required qualifications
The applicant must have:
* obtained a Master´s degree in a relevant subject area prior to the starting 
date
* fluency in English and excellent communication skills.

Preferred qualifications
We are looking for a highly motivated candidate with a background in structural 
biology or biochemistry with a solid experience of protein expression and 
purification.

Supervisors
Professor Jette Sandholm Kastrup (main supervisor, email: j...@sund.ku.dk, 
direct phone: +45 35 33 64 86, Michael Gajhede (co-supervisor, email: 
m...@sund.ku.dk; direct phone: +45 35 33 64 07) and David E. Gloriam (project 
leader and co-supervisor, email: david.glor...@sund.ku.dk; direct phone: +45 35 
33 61 62).
Department of Drug Design and Pharmacology, Faculty of Health and Medical 
Sciences, University of Copenhagen.

General job description
Your key tasks as a PhD fellow at the Faculty are to:
* manage and carry through your research project
* take PhD courses
* write scientific articles and your PhD thesis
* participate in national and international congresses and scientific meetings
* stay at an external research institution, preferably abroad
* teach and disseminate your research
* participate in the undergraduate teaching of students in pharmaceutical 
sciences

Key criteria for the assessment of applicants
* Professional qualifications relevant to the PhD programme
* Relevant work experience
* Previous publications
* The grade point average achieved
* Other professional activities
* Language skills
* The successful applicant is also required to be enterprising and to possess 
good interpersonal skills

Formal requirements
The position is available for a three-year period for applicants holding a 
relevant master´s degree.

It is a prerequisite that the PhD candidate is enrolled as a PhD student at the 
Faculty of Health and Medical Sciences according to the rules stipulated in the 
Ministerial order on the PhD programme at the universities (PhD order) from the 
Ministry of Science, Innovation, and Higher Education and the guidelines for 
the PhD programme at the Faculty of Health and Medical Sciences.

The PhD fellow is expected to be affiliated to the graduate programme in 
pharmaceutical sciences, Drug Research Academy.

Terms of employment
Salary and other terms of employment are stated in the Protocol on PhD Research 
Fellows signed by the Danish Ministry of Finance and AC (the Danish 
Confederation of Professional Associations).

Questions
For further information, applicants may contact the supervisor or Administrator 
Marianne W. Jørgensen, email: marianne.joergen...@sund.ku.dk, direct phone: +45 
35 33 64 49.

For more information on working and living in Denmark visit www.ism.ku.dk 
(International staff mobility) and www.workingconditions.ku.dk.

How to apply
Applicants are requested to

[ccp4bb] PhD student position available at Department of Drug Design and Pharmacology, University of Copenhagen

2014-09-02 Thread Michael Gajhede
If you are interested please follow the link: 
http://employment.ku.dk/phd/?show=683707

Best regards

Michael Gajhede

Michael Gajhede
Professor

Faculty of Health and Medical Sciences
Biostructural Research
University of Copenhagen
Jagtvej 162
2100 Copnhagen Ø
Denmark

TEL +45 35336000
DIR +45 35336407
m...@sund.ku.dk<mailto:m...@sund.ku.dk>
www.ku.dk<http://www.ku.dk/>


[Description: Description: Description: Description: Description: Description: 
SUND_bomaerke_UK]




[ccp4bb] Vacant position in structural biology at the Department of Drug Design and Pharmacology, University of Copenhagen

2013-10-17 Thread Michael Gajhede
Please see announcement below that can also be seen at 
http://www.ku.dk/english/available_positions/vip/ as "Post doctoral 
position/assistant professor" with application deadline November 1. If you wish 
to apply, you will need to use the link above to the electronic application 
system.

All the best wishes

Michael Gajhede


Post doctural position/assistant professor

Identification of compounds that are potential drugs targeting the putative 
breast cancer oncogene KDM5B

The Department of Drug Design and Pharmacology, Faculty of Health and Medical 
Sciences at the University of Copenhagen is offering a two-year post doctoral 
position/assistant professor withinIdentification of compounds that are 
potential drugs targeting the putative breast cancer oncogene KDM5Bcommencing 
January 1 2014 or soon thereafter.

The project is a collaboration between Assoc. Prof. Henrik Franzyk from the 
Natural Product Research group and the Chromatin Modifications group from 
Biostructural Research, both units located at the Department of Drug Design and 
Pharmacology.

Brief project description
The project aims at the identification of new peptide- and 
oligonucleotide-based scaffolds for potential drugs targeting the histone 
demethylase and putative oncogene KDM5B. The position will be anchored at the 
Biostructural Research section, Department of Drug Design and Pharmacology, 
University of Copenhagen. The Biostructural Research section provides the basis 
for structural and functional studies of a wide range of different proteins 
involved in health and disease.

Further information
For further information, please contact Professor Michael 
gajhede...@sund.ku.dk<mailto:m...@sund.ku.dk>, tel. +45 3533 6407.

Qualifications required
The preferred applicant will be an experimentally oriented scientist who 
preferably has experience with structural biology and enzymatic assays. The 
applicant should also have an interest in peptide chemistry.

Terms of employment
The terms of employment and payment are according to the agreement between the 
Ministry of Finance and The Danish Confederation of Professional Associations 
on Academics in the State.

As an equal opportunities employer, the University of Copenhagen encourages all 
qualified applicants to apply, regardless of gender, age, religion and ethnic 
origin.

Application
Applications should include the following parts:

1) Application cover letter indicating motivation
2) Curriculum vitae
3) Copies of relevant diplomas
4) A complete list of publications indicating articles relevant to the 
position, including copies of these articles (max. 5)
5) Recommendation letters if relevant

The parts must be clearly labeled with the above-mentioned numbers.

Applications will not be taken into consideration, if the requirements listed 
above are not met.

The application will be assessed according to the Ministerial Order no. 242 of 
13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen encourages all interested in this position to 
apply.

Please submit the application with the required attachments by clicking on 
"apply online" below. Only online applications will be accepted. The closing 
date for applications is 23:59, November 1 2013.

Applications received after the deadline will not be considered.

The Faculty of Health Sciences comprises app. 7500 students, app. 1500 PhD 
students and app. 3200 employees. The Faculty creates new knowledge and 
recognition through its core activities: research, teaching, knowledge sharing 
and communication. With basic research fields ranging from molecular studies to 
studies of society, the Faculty contributes to a healthy future through its 
graduates, research findings and inventions for the benefit of patients and the 
community.

Apply 
online<https://ssl1.peoplexs.com/Peoplexs22/CandidatesPortalNoLogin/ApplicationForm.cfm?PortalID=3789&VacatureID=611138>

The University of Copenhagen actively influences current and future generations 
through excellent research, education and co-operation. UCPH is one of the 
highest ranked universities in Europe and is Denmark´s oldest university, 
founded in 1479. Today, the University has 37,000 students and 9,000 employees 
affiliated across six faculties: humanities, law, natural sciences, social 
sciences, health sciences and theology. www.ku.dk/english/.

Frist: 01-11-2013
Arbejdsgiver: Det Sundhedsvidenskabelige Fakultet



Michael Gajhede
Professor

Faculty of Health and Medical Sciences
Biostructural Research
University of Copenhagen
Jagtvej 162
2100 Copnhagen Ø
Denmark

TEL +45 35336000
DIR +45 35336407
m...@sund.ku.dk<mailto:m...@sund.ku.dk>
www.ku.dk<http://www.ku.dk/>


[Description: Description: Description: Description: Description: Description: 
SUND_bomaerke_UK]

<>

[ccp4bb] PhD student opening, Department of Drug Design and Pharmacology, University of Copenhagen

2012-10-31 Thread Michael Gajhede

Please note the opening for the project:
Neutron and X-ray structural studies of the epigenetic regulator KDM5B and its 
interaction partners in oncogene regulation
With application deadline 8 november 2012. More details at 
http://www.farma.ku.dk/index.php?id=11675
Best wishes
Michael Gajhede

Michael Gajhede
Professor

Faculty of Health and Medical Sciences
Biostructural Research
University of Copenhagen
Jagtvej 162
2100 Copnhagen Ø
Denmark

TEL +45 35336000
DIR +45 35336407
m...@sund.ku.dk<mailto:m...@sund.ku.dk>
www.ku.dk<http://www.ku.dk/>


[SUND_bomaerke_UK]

<>

[ccp4bb] Two postdoctoral positions at Department of Molecular Drug Research, University of Copenhagen

2011-11-07 Thread Michael Gajhede
1. Position

Job description
A postdoctoral position is available from 01.01.2012-31.12.2013. The successful 
candidate will focus on the identification of interaction partners of the 
histone demethylase PLU-1 and on structural studies of stable PLU-1 complexes 
involved in gene regulation. The project will be conducted within the framework 
of the University of Copenhagen Programme of Excellence on Epigenetics, a 
programme involving research groups at the Biotech Research and Innovation 
Centre (BRIC) and the Department of Medicinal Chemistry.  Experience with 
recombinant protein expression, protein purification and biochemical 
characterisation of mammalian intracellular proteins will be an advantage. 
Interest in the application of scattering methods such as X-ray Crystallography 
and Small Angle X-ray Scattering (SAXS) is also required, but no prior 
experience with these techniques is necessary.

Terms of employment
Terms of appointment and payment are in accordance with the agreement between 
the Danish Ministry of Finance and the Danish Federation of Professional 
Associations.

Applying
Send your application via http://www.ku.dk/stillinger/VIP (select 'send 
ansøgning' at the bottom of the page). The deadline for applying is 1 December 
2011.

Questions
Further information about the position and the project are available from 
Professor Michael Gajhede, Biostructural Research 
(www.farma.ku.dk/BR<http://www.farma.ku.dk/BR>), Department of Molecular Drug 
Research, University of Copenhagen, tel. 35336407, email 
m...@farma.ku.dk<mailto:m...@farma.ku.dk>.

The University of Copenhagen wishes to reflect the diversity of society and 
welcomes applications from all qualified candidates regardless of personal 
background.

2. Position

Job description
A postdoctoral position is available from 15.12.2011-31.6.2013. The successful 
candidate will focus on in-vitro characterisation, structural studies and 
inhibitor identification of the chromatin modifying TET proteins. The project 
will be conducted within the framework of the University of Copenhagen 
Programme of Excellence on Epigenetics, a programme involving research groups 
at the Biotech Research and Innovation Centre (BRIC) and the Department of 
Medicinal Chemistry. Experience with recombinant protein expression, protein 
purification and biochemical characterisation of mammalian intracellular 
proteins will be an advantage.

Terms of employment
Terms of appointment and payment are in accordance with the agreement between 
the Danish Ministry of Finance and the Danish Federation of Professional 
Associations.

Applying
Send your application via http://www.ku.dk/stillinger/VIP (select 'send 
ansøgning' at the bottom of the page). The deadline for applying is 1 December 
2011.

Questions
Further information about the position and the project are available from 
Professor Michael Gajhede, Biostructural Research 
(www.farma.ku.dk/BR<http://www.farma.ku.dk/BR>), Department of Molecular Drug 
Research, University of Copenhagen, tel. 35336407, email 
m...@farma.ku.dk<mailto:m...@farma.ku.dk>.

The University of Copenhagen wishes to reflect the diversity of society and 
welcomes applications from all qualified candidates regardless of personal 
background.


Professor Michael Gajhede
Department of Medicinal Chemistry
University of Copenhagen
Jagtvej 162
DK-2100 Copenhagen Ø
Denmark
Phone: +45 35336407
Email: m...@farma.ku.dk.dk<mailto:m...@farma.ku.dk.dk>



[ccp4bb] PhD fellowship University of Copenhagen: Nicotinic acetylcholine alpha4beta2 receptor model systems

2010-04-15 Thread Michael Gajhede
General announcement and how to apply: http://www.farma.ku.dk/index.php?id=8206

Project description: http://www.farma.ku.dk/index.php/Project-6/8214/0/

Deadline for applications: Monday 3 May 2010 at 12 o'clock noon

About the group: http://www.farma.ku.dk/BR/

Please contact me if you wish further information.
Best regards 
Michael Gajhede

-- 
Professor Michael Gajhede
Institute of Medicinal Chemistry
University of Copenhagen
Universitetsparken 2
DK-2100 Copenhagen Ø
Denmark
Phone: +45 35306407
Email: m...@farma.ku.dk.dk
 


[ccp4bb] Akta FPLC interface card

2009-09-10 Thread Michael Gajhede
If anyone should have CU-900 interface card (unicorn communication) from
a Akta FPLC system laying around they do not use anymore, we would be
interested in buying it. Sorry for being off topic.
Regards Michael
-- 
Professor Michael Gajhede
Institute of Medicinal Chemistry
University of Copenhagen
Universitetsparken 2
DK-2100 Copenhagen Ø
Denmark
Phone: +45 35306407
Email: m...@farma.ku.dk.dk
 


[ccp4bb] PhD fellowship in structure determination of cys-loop receptors at University of Copenhagen

2009-08-10 Thread Michael Gajhede
General announcement and how to apply : http://www.farma.ku.dk/index.php?id=6811

Project description: http://www.farma.ku.dk/index.php/Project-10/6840/0/

Deadline for applications: Tuesday 25 August 2009 at 12 o'clock noon.

About the group: http://www.farma.ku.dk/BR/

Please contact me if you wish further information.
Best regards 
Michael Gajhede

-- 
Professor Michael Gajhede
Institute of Medicinal Chemistry
University of Copenhagen
Universitetsparken 2
DK-2100 Copenhagen Ø
Denmark
Phone: +45 35306407
Email: m...@farma.ku.dk.dk
 


[ccp4bb] Postdoctoral Position in Macromolecular Crystallography

2008-12-04 Thread Michael Gajhede
A postdoctoral position in macromolecular crystallography is available
at the three Cassiopeia beamlines at Max-Lab in Lund, Sweden, for a
period of two years starting as soon as possible. The Danscatt
consortium (www.danscatt.dk) is funding the position, and the successful
candidate will work full time at Max-Lab. The postdoc will provide
general support to all Cassiopeia users for 1/3 of the working time. The
remaining 2/3 will be dedicated to collaborative projects, including
publications, with Danish macromolecular crystallography laboratories,
and to the development of new directions within macromolecular
crystallography at Cassiopeia. Max-Lab has excellent crystallization
robotics, crystal imaging facilities, and structure determination tools.
With respect to new directions, the post-doc is expected to participate
in:

  * Installation and implementation of a free mounting system for MX
  * Proof of principle studies for a solution SAXS beamline with the
option for microfludics applications
  * Implementation of automated sample changers for crystal mounting
at MX beamlines

The successful candidate will refer to professor Michael Gajhede,
Biostructural Research, Department of Medicinal Chemistry, University of
Copenhagen ([EMAIL PROTECTED]), from whom further details on the position
can be obtained.  Further details concerning the Cassiopeia beamlines
are available from beamline manager Thomas Ursby
[EMAIL PROTECTED], see also cassiopeia.maxlab.lu.se.

On 23 October 2008, the Swedish government expressed support for the
construction of a unique third-generation synchrotron, the Max-IV, which
is planned to house two superb MX beamlines and one beamline for
solution SAXS. The post-doc is invited to participate in the development
of the detailed plans for these beamlines. In addition, the Max-IV may
become the neighbour of the new European neutron spallation source ESS,
which will initiate a completely new era in neutron studies in
structural biology. The post-doctoral position therefore offers a unique
opportunity to establish research in the future European powerhouse of
structural biology. For more information regarding the Max-IV and ESS,
see: www.maxlab.lu.se and www.esss.se.

The Danish user community in structural biology holds a unique position
in frontier structural biology with many recent publications in leading
journals, see examples below. Projects include ion-pumping membrane
proteins, large macromolecular complexes involved in RNA metabolism,
proteins from the immune defence, ligand-gated ion channels and
transporters in the central nervous system, enzymes from the barley
fatty acid metabolism, bacterial carbohydrate modifying enzymes and
enzymes containing iron.

Homepages of Danish MX laboratories: www.farma.ku.dk/BR,
www.bioxray.au.dk, www.ccs.ki.ku.dk, www.crc.dk, and www.kemi.dtu.dk.

Selected recent MX publications from Danish MX laboratories:

  * Pedersen BP et al. Crystal structure of the plasma membrane
proton pump. Nature 2007, 450(7172):-4.
  * Morth JP et al. Crystal structure of the sodium-potassium pump.
Nature 2007, 450(7172):1043-9.
  * Olesen C et al. The structural basis of calcium transport by the
calcium pump. Nature 2007, 450(7172):1036-42.
  * Andersen CB et al. Structure of the exon junction core complex
with a trapped DEAD-box ATPase bound to RNA. Science 2006,
313(5795):1968-72. 
  * Fredslund F et al. Structure of and influence of a tick
complement inhibitor on human complement component 5. Nature
Immunol. 2008, 9(7):753-60. 
  * Weyand F et al. Structure and molecular mechanism of a
nucleobase-cation-symport-1 family transporter. Science 2008,
Published Online October 16, 2008.
  * Naur P et al. Ionotropic glutamate-like receptor delta2 binds
D-serine and glycine. PNAS 2007, 104(35), 14116-21.
  * Vestergaard B et al. A helical structural nucleus is the primary
elongating unit of insulin amyloid fibrils. PLoS Biology 2007,
5(5) e134.

Candidates may apply before receiving their PhD degree, but the
successful candidate must have earned a PhD degree before the start of
the appointment.

Applications should be marked 08-322/MPD-22. Include in five copies: a
current curriculum vitae, copies of relevant diplomas, a complete list
of publications indicating those articles relevant to the position and
copies of same, and a statement of teaching qualifications.

Electronics applications will not be accepted.

Applications should be sent to: 
Faculty of Pharmaceutical Sciences
University of Copenhagen
Universitetsparken 2
DK-2100 Copenhagen
Denmark

Deadline for applications: 15 January 2009 at 12:00 noon.  

-- 
Professor Michael Gajhede
Institute of Medicinal Chemistry
University of Copenhagen
Universitetsparken 2
DK-2100 Copenhagen Ø
Denmark
Phone: +45 35306407
Email: [EMAIL PROTECTED]
 


[ccp4bb] PhD fellowship in structural biology at Department of Medicinal Chemistry, University of Copenhagen

2008-07-11 Thread Michael Gajhede
For more information please follow link and look at the project number 11:

 

http://www.farma.ku.dk/index.php?id=5587

 

 

information on research group:

 

www.farma.ku.dk/br

 

Professor Michael Gajhede

Biostructural research 

Department of Medicinal Chemistry

University of Copenhagen

+45 35336407

 



[ccp4bb] Postdoctoral position in epigenetics,cancer and structural biology at Department of Medicinal Chemistry, University of Copenhagen

2008-05-19 Thread Michael Gajhede
For more information please follow link:

 

http://www.farma.ku.dk/index.php?id=3723
<http://www.farma.ku.dk/index.php?id=3723&tx_ttnews%5btt_news%5d=297&tx_ttne
ws%5bbackPid%5d=3650&cHash=5f344b9168>
&tx_ttnews[tt_news]=297&tx_ttnews[backPid]=3650&cHash=5f344b9168

 

information on research group:

 

www.farma.ku.dk/br

 

Professor Michael Gajhede

Biostructural research 

Department of Medicinal Chemistry

University of Copenhagen

+45 35336407

 



[ccp4bb] Postdoctoral position in structural biology at Department of Medicinal Chemistry, University of Copenhagen

2008-04-30 Thread Michael Gajhede
For more information please follow link:

 

http://www.farma.ku.dk/index.php?id=3723
<http://www.farma.ku.dk/index.php?id=3723&tx_ttnews%5btt_news%5d=291&tx_ttne
ws%5bbackPid%5d=3650&cHash=2c3ad8912e>
&tx_ttnews[tt_news]=291&tx_ttnews[backPid]=3650&cHash=2c3ad8912e

 

 

information on research group:

 

www.farma.ku.dk/br

 

Professor Michael Gajhede

Biostructural research 

Department of Medicinal Chemistry

University of Copenhagen

+45 35336407

 



[ccp4bb] PhD fellowship in structural biology at Department of Medicinal Chemistry, University of Copenhagen

2008-04-25 Thread Michael Gajhede
For more information please follow link:

 

http://www.farma.ku.dk/index.php?id=5392

 

information on research group:

 

www.farma.ku.dk/br

 

Professor Michael Gajhede

Biostructural research 

Department of Medicinal Chemistry

University of Copenhagen

+45 35336407