[Collab] Lectins & health; lectins in millets (Re: Collab Digest, Vol 28, Issue 1)

2024-05-02 Thread Don Osborn
Thank you, Robin, for the clarification. And  no need to apologize. As it
turned out, I personally appreciate the opportunity to check out lignans.
Much to learn.

Regarding lectins, here are some quick takes (sorry,

The Wikipedia article on the subject has a description that touches on
several aspects:
"Lectins are carbohydrate-binding proteins that are highly specific for
sugar groups that are part of other molecules [They] have a role in
recognition at the cellular and molecular level and play numerous roles in
biological recognition phenomena involving cells, carbohydrates, and
proteins. Lectins also mediate attachment and binding of bacteria, viruses,
and fungi to their intended targets."/1

Lectins are present in many plants we consume as food, and are generally
inactivated by boiling or sometimes soaking. Some lectins can be harmful if
consumed raw or in large quantities (don't eat  raw kidney beans,for
example).

Claims made for a lectin-free diet are controversial and at least some of
them are apparently not supported by research./2/3/4  Steven Gundry
advocates for the diet in his book, The Plant Paradox./5/6

For what it's worth, lectin levels in millets, including sorghum, are said
to be low/7 or absent,/8 and Dr. Gundry writes favorably about "millet."/9

That's all I have at this time. (Sorry, no scholarly references.):

Don

DO, EL, MI, US
NAMA

Notes:
1. https://en.wikipedia.org/wiki/Lectin
2. https://en.wikipedia.org/wiki/Lectin-free_diet
3. https://www.webmd.com/diet/what-to-know-plant-paradox-diet
4. https://www.forbes.com/health/nutrition/lectin-free-diet/
5. https://www.goodreads.com/en/book/show/33630505
6.
https://www.redpenreviews.org/reviews/the-plant-paradox-the-hidden-dangers-in-healthy-foods-that-cause-disease-and-weight-gain/
7. https://www.trenpa.in/blogs/millets/do-millets-contain-lectin-and-gluten
8. https://creativeinmykitchen.com/the-4-gluten-free-and-lectin-free-grains/
9. https://gundrymd.com/millet-lectin-free-carb/


On Thu, May 2, 2024 at 9:10 AM Robin Asbell via Collab <
collab@lists.millets2023.space> wrote:

> I apologize for mixing up lignans and lectins, It's lectins that Dr Gundry
> has made into the new food phobia.
> It's hard to keep up.
>
> On Thu, May 2, 2024 at 7:02 AM 
> wrote:
>
>> Send Collab mailing list submissions to
>> collab@lists.millets2023.space
>>
>> To subscribe or unsubscribe via the World Wide Web, visit
>> https://lists.millets2023.space/mailman/listinfo/collab
>> or, via email, send a message with subject or body 'help' to
>> collab-request@lists.millets2023.space
>>
>> You can reach the person managing the list at
>> collab-owner@lists.millets2023.space
>>
>> When replying, please edit your Subject line so it is more specific
>> than "Re: Contents of Collab digest..."
>>
>>
>> Today's Topics:
>>
>>1. Lignans & health; lignans in millets (Re: Collab Digest, Vol
>>   27, Issue 23) (Don Osborn)
>>
>>
>> --
>>
>> Message: 1
>> Date: Wed, 1 May 2024 12:54:16 -0400
>> From: Don Osborn 
>> To: Robin Asbell 
>> Cc: collab@lists.millets2023.space
>> Subject: [Collab] Lignans & health; lignans in millets (Re: Collab
>> Digest, Vol 27, Issue 23)
>> Message-ID:
>> > d...@mail.gmail.com>
>> Content-Type: text/plain; charset="utf-8"
>>
>> Thank you Robin. This is the first I recall hearing about lignans.
>>
>> A quick search online gave me three impressions: (1) lignans are not the
>> same as lignins; (2) defining lignans quickly gets into organic chemistry;
>> and (3) lignans in the human diet (they come from plants) are often
>> referred to in positive terms,
>>
>> In fact, I had a hard time finding negative takes on lignans, and those
>> related to very high consumption of flax (one of the foods particularly
>> high in these compounds; all grain, including millets and sorghum, have
>> lignans, but at more moderate levels). Can you give us more info, Robin?
>>
>> Here's a definition of lignans that I found helpful (many, including the
>> one in WIkipedia,/1 are more technical):
>> "The lignans are bioactive, non-nutrient, non-caloric phenolic plant
>> compounds that are found in highest concentration in flax and sesame seeds
>> and in lower concentrations in grains, other seeds, fruits and vegetables.
>> The enterolignans (sometimes referred to as mammalian lignans) are
>> metabolites of food lignans produced by human intestinal bacteria. They
>> have been identified in human urine and plasma. Their weak estrogenic and
>> other biochemical properties suggest potential for nutritional
>> significance
>> in the prevention of cardiovascular and other chronic diseases."/2
>>
>> Regarding millets a different article states:
>> "Millets are rich in lignans, upon digestion they can be converted into
>> animal lignans by gut microbiota, and those animal lignans have been shown
>> to protect against certain chronic diseases, like 

Re: [Collab] Collab Digest, Vol 28, Issue 1

2024-05-02 Thread Robin Asbell via Collab
I apologize for mixing up lignans and lectins, It's lectins that Dr Gundry
has made into the new food phobia.
It's hard to keep up.

On Thu, May 2, 2024 at 7:02 AM 
wrote:

> Send Collab mailing list submissions to
> collab@lists.millets2023.space
>
> To subscribe or unsubscribe via the World Wide Web, visit
> https://lists.millets2023.space/mailman/listinfo/collab
> or, via email, send a message with subject or body 'help' to
> collab-request@lists.millets2023.space
>
> You can reach the person managing the list at
> collab-owner@lists.millets2023.space
>
> When replying, please edit your Subject line so it is more specific
> than "Re: Contents of Collab digest..."
>
>
> Today's Topics:
>
>1. Lignans & health; lignans in millets (Re: Collab Digest, Vol
>   27, Issue 23) (Don Osborn)
>
>
> --
>
> Message: 1
> Date: Wed, 1 May 2024 12:54:16 -0400
> From: Don Osborn 
> To: Robin Asbell 
> Cc: collab@lists.millets2023.space
> Subject: [Collab] Lignans & health; lignans in millets (Re: Collab
> Digest, Vol 27, Issue 23)
> Message-ID:
>  d...@mail.gmail.com>
> Content-Type: text/plain; charset="utf-8"
>
> Thank you Robin. This is the first I recall hearing about lignans.
>
> A quick search online gave me three impressions: (1) lignans are not the
> same as lignins; (2) defining lignans quickly gets into organic chemistry;
> and (3) lignans in the human diet (they come from plants) are often
> referred to in positive terms,
>
> In fact, I had a hard time finding negative takes on lignans, and those
> related to very high consumption of flax (one of the foods particularly
> high in these compounds; all grain, including millets and sorghum, have
> lignans, but at more moderate levels). Can you give us more info, Robin?
>
> Here's a definition of lignans that I found helpful (many, including the
> one in WIkipedia,/1 are more technical):
> "The lignans are bioactive, non-nutrient, non-caloric phenolic plant
> compounds that are found in highest concentration in flax and sesame seeds
> and in lower concentrations in grains, other seeds, fruits and vegetables.
> The enterolignans (sometimes referred to as mammalian lignans) are
> metabolites of food lignans produced by human intestinal bacteria. They
> have been identified in human urine and plasma. Their weak estrogenic and
> other biochemical properties suggest potential for nutritional significance
> in the prevention of cardiovascular and other chronic diseases."/2
>
> Regarding millets a different article states:
> "Millets are rich in lignans, upon digestion they can be converted into
> animal lignans by gut microbiota, and those animal lignans have been shown
> to protect against certain chronic diseases, like cancer and heart
> disease."/3
>
> Sorghum apparently does contain lignans./4
>
> In general, "Lignan-rich foods are part of a healthy diet"/5 Various
> research articles explore specific positive effects of lignans, including
> for cardiovascular health,/2 stress perception,/6 and possibly
> pot-menopausal symptoms./7 I see some suggestions of anti-cancer effects./3
> /7 Lignans have an important role in gut microbiota, apparently with
> implications for health in various ways./8
>
> The above is neither comprehensive, nor necessarily representative with
> regard to the thinking about lignans, but as a non-specialist in this
> field, this is what I came up with. It's important to note that lignans are
> a class of compounds, and not one single thing, so perhaps there are
> differences in the effects of various lignins? Interested to learn more.
>
> Don
>
> DO, EL, MI, US
> NAMA
>
> Notes:
> 1. https://en.wikipedia.org/wiki/Lignan
> 2. Peterson, Julia et al. ?Dietary lignans: physiology and potential for
> cardiovascular disease risk reduction.? Nutrition reviews vol. 68,10
> (2010): 571-603. https://doi.org/10./j.1753-4887.2010.00319.x
> 3. Babele, Piyoosh K et al. ?Mainstreaming orphan millets for advancing
> climate smart agriculture to secure nutrition and health.? Frontiers in
> plant science vol. 13 902536. 12 Aug. 2022,
> https://doi.org/10.3389/fpls.2022.902536
> 4. https://www.glnc.org.au/resource/sorghum/
> 5. https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/lignans
> 6. Micek, Agnieszka et al. ?Negative Association of Lignan and Phytosterol
> Intake with Stress Perception during the COVID-19 Pandemic-A Polish Study
> on Young Adults.? *Nutrients* vol. 16,3 445. 2 Feb. 2024,
> https://doi.org/10.3390/nu16030445
> 7. Jang, Won Young et al. ?Antioxidant, Anti-Inflammatory, Anti-Menopausal,
> and Anti-Cancer Effects of Lignans and Their Metabolites.? *International
> journal of molecular sciences* vol. 23,24 15482. 7 Dec. 2022,
> https://doi.org/10.3390/ijms232415482
> 8. Senizza, Alice et al. ?Lignans and Gut Microbiota: An Interplay
> Revealing Potential Health Implications.? Molecules (Basel,