[ccp4bb] Two postdoc positions in enzymology at Michigan State University

2019-07-30 Thread Hu, Jian
Job description: Two postdoctoral research associate positions in enzymology for two separated projects are immediately available in the laboratories of Dr. Robert Hausinger (Department of Microbiology & Molecular Genetics) and Dr. Jian Hu (Department of Biochemistry & Molecular Biology) at Mi

[ccp4bb] General interest

2019-07-30 Thread John R Helliwell
Dear Colleagues, For your general interest, you can find the lecture slides that I presented at ACA 2019 in the Transactions Symposium on Data via the weblink here:- https://forums.iucr.org/viewtopic.php?f=39&t=421 Best wishes, John Emeritus Professor John R Helliwell DSc Chairman of IUCr CommDa

Re: [ccp4bb] challenges in structural biology

2019-07-30 Thread Gloria Borgstahl
Sorry to be late chiming in on this post (survived RAGBRAI). I think the challenges (crystallization, perdeuteration) and benefits of neutron crystallography (where are those protons) could be included. We are now in an era of using cryotrapping with neutrons which I think is really cutting edge

Re: [ccp4bb] cbf to sfrm

2019-07-30 Thread Andreas Förster
Dear Tim and all, if anyone is interested in converting EIGER HDF5 files directly to Bruker format (SFRM), please contact me. There's no need to go via CBF or similar intermediaries. All best. Andreas On Sun, Jul 28, 2019 at 12:25 PM Tim Gruene wrote: > Dear all, > > recently the conversi

Re: [ccp4bb] Combining MR and SIR phases

2019-07-30 Thread Clemens Vonrhein
Dear Luke, sorry for the late reply, but e.g. autoSHARP would do the MR-XYZ combination (it doesn't really matter what XYZ is: SAD, SIRAS, SIR, MIR, MIRAS, MAD). See [1] for combining the two approaches. Cheers Clemens [1] https://www.globalphasing.com/sharp/wiki/index.cgi?RunAutoSharp http

[ccp4bb] ISOLDE dev builds now available

2019-07-30 Thread Tristan Croll
Hi all, Since the release of ISOLDE 1.0b3 I've begun releasing regular (weekly~fortnightly) development builds of ISOLDE. These are built against the ChimeraX daily build at the time of release - if you download a ChimeraX-daily build and install ISOLDE in the usual way via Tools/More Tools..

[ccp4bb] Postdoc and PhD position in Oxford

2019-07-30 Thread Christian Siebold
Dear all   We are looking for a Postdoctoral Research Scientist and a PhD student to join our group at the Division of Structural Biology (STRUBI), University of Oxford, UK. Research in the Siebold group is focused on the structural biology of mammalian cell surface signalling pathways invo

Re: [ccp4bb] challenges in structural biology

2019-07-30 Thread CCP4BB
Hi It's pretty much what the powder people do when using Rietveld refinement, isn't it? As far as I know, they fit a calculated curve from their structure to a 1D trace of the powder pattern (happy to be corrected on this). All you need to do is extend this to 3D - there may be enough work ther

Re: [ccp4bb] challenges in structural biology

2019-07-30 Thread Loes Kroon-Batenburg
Dear Jacob, That should indeed be our ultimate goal: refining against the image data rather than against process data. This would require a good model for the crystal, mosaicity being an important parameter in this, and for the internal variation in the molecular structure. Modelling the Bragg

[ccp4bb] Postdoc in DNA Repair Structural Biology

2019-07-30 Thread Laurence Pearl
A Post-doctoral position funded by Cancer Research UK is available from 1st October 2019 in the laboratory of Prof. Laurence Pearl FRS and Dr. Antony Oliver, in the Genome Damage and Stability Centre at the University of Sussex, to study the structure and mechanism of multi-protein complexes inv