[ccp4bb] 43rd Mid-Atlantic Macromolecular Crystallography Meeting

[Charles Pemble]

*43**rd** Mid-Atlantic Macromolecular Crystallography Meeting*

*May 30 – June 1, 2013*

*Duke University*

*Durham, NC*




The 43rd Mid-Atlantic Macromolecular Crystallography Meeting (MAMCM) will
be held at Duke University in Durham, North Carolina.  This meeting fosters
discussion and interaction among structural biologists from around the
Mid-Atlantic region. Registration is now open at http://www.mid-atlantic.org.
The deadline for registration is May 15th.



This year will feature keynote speaker Tom Terwilliger from Los Alamos
National Lab, workshops on PHENIX and MolProbity, plus many talks & posters
on new and exciting research. Presentations will be selected from submitted
abstracts and preference will be given to young researchers.  The best
presentation and poster by a Graduate Student & Postdoctoral Fellow will be
awarded.  We encourage you to submit your abstracts and sign up for the
workshops as these are separate processes from registration.






*IMPORTANT: *A block of rooms have been reserved at the Millennium hotel as
well as the Duke dormitories.  The deadline for reserving a room at the
Millennium is May 9th.





With best wishes on behalf of the primary Organizing Committee,


Charlie Pemble

_

Charles W. Pemble IV, Ph.D.

Duke University Medical Center

308 Research Drive

LSRC, A06

Durham, NC 27708

charles.pem...@duke.edu

[ccp4bb] Postdoctoral position in Chemical & Structural Biology of PPIs, Ciulli Lab, College of Life Science, Dundee

[Alessio Ciulli]

Reference Number:LS0313

Job Title:Postdoctoral Research ASsociate

College:College of Life Sciences

School:Life Sciences Research

Division:Biological Chemistry and Drug Discovery

Grade:*Grade 7 (£29,541 - £36,298)** *

Job Category:Research

Closing Date:1 May 2013



A postdoctoral position is available immediately in the new laboratory of
Dr. Alessio Ciulli (http://www.lifesci.dundee.ac.uk/people/alessio-ciulli)
to work on a project funded by the BBSRC. We are looking for an
enthusiastic and motivated post-doctoral scientist to join a team of
researchers broadly interested in Chemical & Structural Biology of
Protein-Protein Interactions.



You will investigate structure-function relationships within a family of
human proteins containing bromodomains. We are interested in unveiling the
molecular basis underpinning selectivity of small-molecule probes targeting
such domain, which read histone post-translational modifications and are
found in histone acetyl transferases and other chromatin-associated
proteins involved in the epigenetic regulation of gene expression. The
ultimate goal of the research is to aid elucidation of the roles of
individual bromodomains in human biology and disease.



The project will involve protein engineering, purification and
crystallization, structure solution by X-ray crystallography, and
structural and biophysical techniques to study protein-ligand interactions
and determine structure-activity relationships. It is in collaboration with
Prof. Stefan Knapp at the Structural Genomics Consortium of Oxford
University (see Molecular Biosystems (2011) 7, 2899-908).



*The ideal candidate will posses or be able to demonstrate the following: *



• A PhD with outstanding academic track record and at least one first
authored publication in an internationally recognized peer-reviewed journal
(published or in press)
• Enthusiasm for Science
• Independence
• Strong background in protein purification and crystallography, X-ray data
collection (in-house and at synchrotrons), structure solution and model
refinement
• Experience with biophysical techniques studying protein-ligand
interactions; a strong interest in fragment-based / structure-based drug
design and/or protein NMR would be advantageous
• Capable of working in a team, but able to plan and work independently
• Excellent communication skills and knowledge of the English language are
essential



*Ciulli lab / College of Life Sciences / Division of Biological Chemistry &
Drug Discovery:*



You will be working in a highly international research group that operates
across the disciplines of chemical & structural biology, molecular
biophysics, medicinal chemistry and drug design. More information on our
group can be found on http://www-ciulli.ch.cam.ac.uk/index.htm. Training,
as required, will be provided in a well-equipped, well-funded and
supportive environment enabling the successful candidate to extend skills
and expertise.



The College of Life Sciences is equipped with state-of-the-art facilities
to conduct cutting-edge research in all aspects of modern chemical biology,
structural biology and molecular biophysics.


The Division of Biological Chemistry & Drug Discovery (BCDD) aims to
discover chemical solutions to biological problems through excellence in
basic and applied multidisciplinary research. For further information about
the Division of Biological Chemistry & Drug Discovery, please consult our
website: http://www.lifesci.dundee.ac.uk/research/bcdd.



This post is available until December 2014.



Informal enquiries may be made to Dr. Alessio Ciulli, e-mail:
a.ciu...@dundee.ac.uk.



*How to apply:*

* *

To apply on-line please visit: www.dundee.ac.uk/jobs.  If you are unable to
apply on-line please contact Human Resources on (01382) 386209 (answering
machine) for an application pack.  Please quote reference number LS0313.


The University of Dundee is committed to equal opportunities and welcomes
applications from all sections of the community.

* *

*The University of Dundee is a Scottish Registered Charity, No. SC015096.*

[ccp4bb] Job Post- Sr Scientist Protein Crystallization at AbbVie, North Chicago

[Longenecker, Kenton L]

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed 
in 2013 following separation from Abbott. AbbVie combines the focus and passion 
of a leading-edge biotech with the expertise and capabilities of a 
long-established pharmaceutical leader to develop and market advanced therapies 
that address some of the world's most complex and serious diseases. In 2013, 
AbbVie will employ approximately 21,000 people worldwide and markets medicines 
in more than 170 countries.



The Structural Biology Group at AbbVie is seeking a motivated and talented 
scientist to join the Crystallization Group. The successful candidate will be 
responsible for conducting biological macromolecule crystallization experiments 
in support of structure based drug design. The candidate should be 
knowledgeable in protein handling, purification and characterization techniques 
and have excellent communication skills. The individual must be able to work 
consistently on multiple projects in parallel and be able to adjust to rapidly 
changing priorities. They should be highly self-motivated, be able to work 
independently in their area of expertise and contribute collaboratively with a 
wide range of teams.

For more information, please visit the following link and apply online:
http://abbvie.taleo.net/careersection/2/jobdetail.ftl?lang=en&job=13015N

www.abbvie.com

Regards,

Kenton Longenecker
AbbVie, Inc
1 North Waukegan Road
North Chicago, IL 60064

[ccp4bb] Postdoc position at SLS

[Meitian Wang]

http://www.psi.ch/pa/offenestellen/0560-4
Postdoctoral Fellow
Next Generation Detector for Protein Crystallography
Your tasks
Built on the success of PILATUS detector technology, PSI and Dectris Ltd. are 
developing the next generation single-photon counting detector (EIGER) 
featuring smaller pixel size, higher frame rate and dynamic range. The proposed 
project is to exploit PILATUS and EIGER detectors in protein crystallography 
applications:
Systematic data acquisition and processing optimization using PILATUS 2M/6M 
detectors
Development of fast data acquisition and processing methods with EIGER 1M 
detector in protein micro-crystallography
Commissioning of the EIGER 16M detector at a protein crystallography beamline
Your profile
You hold a PhD degree in (bio-) chemistry or physics and have several years of 
experience in protein crystallography. Working knowledge for data processing 
programs and various phasing and refinement software is a must. Experience in 
computer programming would be a significant advantage. If you are a good team 
player with fine communication skills and sense of responsibility, this 
position will offer a great opportunity for you to develop your research career 
in an exciting and highly multidisciplinary environment.

For further information please contact Dr Meitian Wang, phone +41 56 310 41 75 
or Dr Clemens Schulze-Briese, phone +41 56 500 21 20.

Please submit your application online (including list of publications and 
addresses of referees) for the position as a Postdoctoral Fellow (index no. 
6112-00).

Paul Scherrer Institute, Human Resources Management, Elke Baumann, 5232 
Villigen PSI, Switzerland


__
Meitian Wang
Swiss Light Source at Paul Scherrer Institut
CH-5232 Villigen PSI - http://www.psi.ch/sls/
Phone: +41 56 310 4175

[ccp4bb] Fwd: MISSCA 2013 - Como 9th-12th 2013

[Maria Sola i Vilarrubias]

Dear all,

Please find below the announcement of the MISSCA meeting 2013 which will be
held in Como (Italy) next September.

Best wishes,

Maria.


Dear All,

I am pleased to draw you attention on the *First Meeting of the Italian,
Spanish and Swiss Crystallographic Associations*. Organised in the
beautiful surroundings of Villa Olmo, on the shore of the Lake of *Como (**
Italy)*, the meeting will take place in *Sep**temb**er 9th - 12th 2013*.

The Meeting will not only contribute to broaden the scientific contacts
among the Members of the three Crystallographic communities, yet it is
certainly attractive for scientists from other Countries and neighbouring
fields.

Early bird *registrations** *are now open, as it is the submission of *
contributions*.

A limited number of *grants *is available for undergraduate or PhD
students, as well as for post-doc researchers, less than thirty-five years
old.

You may find more information visiting the Meeting web page at*
http://missca.dsat.uninsubria.it/missca*.

I am at your disposal for any information you may need.

Looking forward to meeting you in Como,
Kind Regards

Simona Galli
on behalf of the Organising Committee

-- 
***
Simona Galli, Dr
Dipartimento di Scienza e Alta Tecnologia
Università dell'Insubria
Via Valleggio, 11
22100 Como - Italy

e-mail: simona.ga...@uninsubria.it
tel:+39-031-2386627
fax:+39-031-2386630
url: scienze.como-uninsubria.it/sgalli

***


-- 
Maria Solà
Dep. Structural Biology
IBMB-CSIC
Baldiri Reixach 10-12
08028 BARCELONA
Spain
Tel: (+34) 93 403 4950
Fax: (+34) 93 403 4979
e-mail: maria.s...@ibmb.csic.es



-- 
Maria Solà
Dep. Structural Biology
IBMB-CSIC
Baldiri Reixach 10-12
08028 BARCELONA
Spain
Tel: (+34) 93 403 4950
Fax: (+34) 93 403 4979
e-mail: maria.s...@ibmb.csic.es