[ccp4bb] Immediate opening...

2016-10-01 Thread Williams, John Charles
Please see:

http://chm.tbe.taleo.net/chm04/ats/careers/requisition.jsp?org=CITYOFHOPE=1=7760

We anticipate filling the position immediately.  No need to reapply if you have 
do so already.


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Crystallographer and Computational Modeler

Position Summary and Key Responsibilities:

This is an extraordinary opportunity to join the efforts to develop a new class 
of immunotherapeutics in laboratory of Professor John Williams at the Beckman 
Research Institute at the City of Hope, a world class institute that played 
essential roles in the development and translation of recombinant insulin and 
humanization of monoclonal antibodies and continues to lead in the development 
CAR T cell and other novel therapeutic approaches. The position will be one of 
five new research scientist positions in Professor Williams' laboratory funded 
by an innovative biotechnology company focused on the discovery and development 
of novel best-in-class immunotherapeutics for the treatment of cancer. The 
breakthrough technology that underpins the research platform was pioneered in 
the Williams lab. It is anticipated that the successful applicants may have the 
opportunity to transition into the drug discovery or pre-clinical development 
organizations of the biotechnology company in the future.

Responsibilities:

Crystallization
Structure determination
Modeling and Computation

Minimum Education and Skills Required for Consideration:

PhD in biophysics, structural biology, biochemistry or related field
Protein purification and analytical characterization
All aspects of protein crystallography – crystallization, crystallization 
optimization, data collection (in-house/synchrotron), structure determination 
and refinement, structure analysis
Computational modeling (familiarity with Schrodinger or other packages)
Independence
Excellent written and verbal communication skills
Good problem solving skills
Ability to work effectively in a team
Post-Doctoral and/or Industrial experience is desirable

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational 
institution with over 4000 employees, is dedicated to the prevention and cure 
of cancer and other life-threatening diseases and guided by a compassionate, 
patient-centered philosophy. Founded in 1913 and headquartered in Duarte, 
California, City of Hope is a remarkable non-profit institution, where 
compassion and advanced care go hand-in-hand with excellence in clinical and 
scientific research. City of Hope is a National Cancer Institute designated 
Comprehensive Cancer Center and a founding member of the National Comprehensive 
Cancer Network, an alliance of the nation’s 20 leading cancer centers that 
develops and institutes standards of care for cancer treatment.

City of Hope is an equal opportunity employer.  All qualified applicants will 
receive consideration for employment without regard to race, religion, color 
national origin, sex, age, status as a protected veteran, or status as a 
qualified individual with disability.

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[ccp4bb] Fwd: [ccpem] Postdoctoral position in cryo-EM of membrane protein complexes at PSI

2016-10-01 Thread Schertler Gebhard (PSI)



Prof. Gebhard F.X. Schertler
Head of Biology and Chemistry
Paul Scherrer Institut
Laboratory of Biomolecular Research, BMR
OFLC 109
CH-5232 Villigen PSI
gebhard.schert...@psi.ch
phone +41 56 310 4265

Anfang der weitergeleiteten E‑Mail:

Von: "Korkhov Volodymyr (PSI)" 
>
Datum: 30. September 2016 um 14:04:02 MESZ
An: >
Betreff: [ccpem] Postdoctoral position in cryo-EM of membrane protein complexes 
at PSI
Antwort an: "Korkhov Volodymyr (PSI)" 
>

A postdoctoral position is available in the group of Prof. Volodymyr M. Korkhov 
at Paul Scherrer Institute (PSI) and ETH Zurich, to work on structure and 
function of membrane-associated signal transduction complexes using electron 
cryo-microscopy (cryo-EM) and single particle analysis.
The successful candidate will have expertise and a track record in cryo-EM and 
single particle analysis. The candidate will be experienced in molecular 
biology, including cloning, heterologous protein expression and purification. 
Previous experience with biochemistry of membrane proteins will be an advantage 
but not a prerequisite. The candidate will be able to work independently and 
will have excellent teamwork and communication skills.
The Korkhov group is integrated into the Laboratory of Biomolecular Research at 
PSI and has full access to all facilities and instruments for protein 
expression, purification, biochemical and biophysical analysis. In addition, 
the group benefits access to the PSI crystallization facility and the Swiss 
Light Source synchrotron radiation facility. The group benefits from the 
in-house 200 kV screening transmission electron microscope (JEOL JEM2200), 
planned to be upgraded with a direct electron detector. Furthermore, the group 
has full access to all research facilities at ETH Zurich, including the K2 and 
Falcon II direct detector-equipped Titan Krios microscope at the ETH Scientific 
Centre for Optical and Electron Microscopy (ScopeM).
Working at PSI provides many benefits, including integration into the PSI/ETH 
Zurich scientific community, high standard of living and a competitive salary. 
This position is offered for one year initially, and is extendable to up to 
four years. The candidate will be expected to obtain a postdoctoral mobility 
fellowship within the first year.
For informal enquiries or to apply for this position the interested candidates 
should send an e-mail to 
volodymyr.kork...@psi.ch. The application 
should include a cover letter describing the candidate`s research interests and 
motivation to apply, the CV and list of publications, and contact details of 
three referees. Additional information can be found here: 
https://www.psi.ch/lbr/korkhov_-volodymyr.