[ccp4bb] Accepting General User Proposals to the National Center for CryoEM Access and Training (NCCAT) - NYC, USA

[Ed Eng]

Dear all,

The National Center for CryoEM Access and Training (NCCAT; 
nccat.nysbc.org) is a new cryoEM service center funded 
by the NIH Common Fund (https://commonfund.nih.gov/). Located at the Simons 
Electron Microscopy Center (semc.nysbc.org), which is a 
part of the New York Structural Biology Center (nysbc.org) in 
New York City, the mission of NCCAT is twofold: to provide nationwide access to 
advanced cryoEM technical capabilities, and to assist users in the development 
of cryoEM skills needed for independent research.

We announce the opening of General User Proposal (GUP) applications for limited 
early access to instrument time. There will be a rolling call for proposals 
with quarterly cycles and access starting the beginning of Q4 2018 (October). 
This initial cycle supports single particle cryoEM data collection on one of 
our existing Titan Krios instruments using a Gatan K2 direct-electron detector. 
Applicants should have pre-screened cryoEM samples with pre-processing results 
(representative micrograph, 2D class averages, and initial reconstruction, if 
available) from the same batch of grids to be submitted for data collection at 
NCCAT. Additional classes of proposals will be opened when the new NCCAT wing 
at NYSBC completes construction (expected the summer of 2019).

NCCAT is committed to an open and transparent application process to ensure 
equal-opportunity nationwide access. For more information see 
http://nccat.nysbc.org/.

Interested users should submit applications through the NCCAT proposal system 
at: http://nccat.nysbc.org/proposalcentral/.

Best,
Ed Eng (NCCAT)

---
Edward T. Eng, Ph.D.
National Center for CryoEM Access and Training
Simons Electron Microscopy Center
New York Structural Biology Center
89 Convent Avenue, NY, NY 10027
nccat.nysbc.org semc.nysbc.org




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1

[ccp4bb] forming a 3D bioinformatics community

[Charles Ballard - UKRI STFC]

Structural bioinformatics is shaping its Community 

Relevance of structural informatics 
Structural bioinformatics has a broad impact across the life sciences and 
provides tools to archive, visualise, analyse, annotate, and predict the 
structure of biological macromolecules. Furthermore, the science of structural 
bioinformatics is traditionally very strong in Europe offering many software 
tools, methodologies, and databases, as well as community-wide prediction 
challenges. Its applications cover research activities from structural biology 
to drug discovery and personalized medicine. We envision that establishing an 
ELIXIR Community will facilitate deeper integration of our broad range of tools 
and services.
The leading research groups and activities in structural bioinformatics in 
Europe are already well represented within the ELIXIR nodes (e.g SWISS-MODEL). 
Several ELIXIR core data resources belong to this field, some of them, such as 
PDBe and CATH are of fundamental importance. Some of the highly cited ELIXIR 
tools also belong to the field of structural bioinformatics.  The 3D-BioInfo 
Community is building on this strength and links to several other 
infrastructures and EC projects. Tools and resources established by the 
3D-BioInfo Community have users in the field of structural biology (Instruct, 
iNEXT), cheminformatics (OpenScreen), system biology (ISBE), and molecular 
simulations (BioExcel) and these will benefit from collaborative projects with 
3D-BioInfo. The 3D-Bioinfo initiative will undoubtedly broaden this scope.

ELIXIR and instruct-ERIC 
The  instruct-ERIC is a most important collaborator and the 3D-BioInfo 
Community will coordinate closely with experimental structural biologists. We 
expect our collaborative projects to help link structural bioinformatic tools 
with emerging structural techniques, to help relate function to structure. This 
will attract new users and support the recognition of both ELIXIR and 
instruct-ERIC services. We expect potential collaborations to involve all five 
ELIXIR platforms (interoperability, data, tools, compute, training).

Goals of the community
The long term goals of the community include: improving integration of 
structural information with data on protein function, genomic variants, disease 
links, and drug action; developing platform for sharing, and benchmarking 
software for protein structure prediction, modeling protein assemblies and 
complexes with various ligands; integrating resources and tools for protein 
structural and evolutionary analyses; development and integration of various 
structural biology enabling tools, in close collaboration with Instruct-ERIC.

How to join 
If you are interested in participating, come to the launch meeting in Basel, 
October 19, 2018, to find out more. You will have the opportunity to present a 
poster and give a flash talk presenting your tools and suggesting how you might 
contribute to community activities. This meeting will be critical for 
collecting ideas for community activities, which will be the basis for a formal 
application to the ELIXIR Heads of Nodes to become an approved community in 
ELIXIR. 
If you would like to give a flash talk (one slide) to advertise a poster at the 
meeting on a proposed ELIXIR activity (involving collaborations across two or 
more groups within an ELIXIR node and preferably involving two or more nodes) 
please send a summary (maximum one page) to c.ore...@ucl.ac.uk outlining the 
groups and ELIXIR nodes involved and the ELIXIR platforms this activity would 
relate to i.e. interoperability, data, tools, compute or training. The proposed 
activity can involve multiple platforms.

Registration site: https://swissmodel.expasy.org/25years/

For information on the timelines for forming an ELIXIR Community in Structural 
Bioinformatics please see: 
https://drive.google.com/file/d/10a5PTWA8b00i7jYeuyOQQ0OXdn-EUoUI/view?usp=sharing
For information on suggested major themes and activities of the 3D-BioInfo 
Community – please see link below. You are welcome to add comments on 
additional activities.
https://drive.google.com/file/d/10DYf1uMg9jaHFOGX7gvKsHIAVRRwqyx1/view?usp=sharing




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1

[ccp4bb] ccp4 release 7.0 update 061 - major update to monomer library!

[Charles Ballard - UKRI STFC]

Dear All

ccp4 release update 061 is now available for updating and downloading.  It 
contains

 * monomer library
 - major update
 - 7000  new monomers
 - 8000 updated monomers

 * refmac
 - updated for new monomer library

 * buccaneer
 - new EM reference structure

This is a recommended update for all CCP4 users.

All the best

Charles (on behalf of the CCP4 core team)

ps - coming soon, ccp4i2 updates for molprobity, and dials 1.10




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1