[ccp4bb] position open to US citizens

[Zhang, Yuzhu - ARS]

https://www.usajobs.gov/GetJob/ViewDetails/576886000





This electronic message contains information generated by the USDA solely for 
the intended recipients. Any unauthorized interception of this message or the 
use or disclosure of the information it contains may violate the law and 
subject the violator to civil or criminal penalties. If you believe you have 
received this message in error, please notify the sender and delete the email 
immediately.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PhD and PostDoc Positions in cryo-EM and cryo-ET

[Stefan Raunser]

PhD and PostDoc Positions (m/f/d) in Electron Cryo-Microscopy (cryo-EM) and 
Tomography (cryo-ET)
There are exciting immediate PhD and Postdoctoral positions in the lab of 
Stefan Raunser in the Department of Structural Biochemistry at the Max Planck 
Institute for Molecular Physiology in Dortmund, Germany. This is a unique 
opportunity to become a part of a world-renowned research institute with a 
diverse faculty with backgrounds in chemistry, biology and physics, and to 
perform interdisciplinary science in a lively and supportive environment!
We seek highly motivated, self-driven and creative thinkers who are prepared to 
take risks in defining and addressing important scientific problems, and who 
use quantitative experimental, computational and/or technical approaches in 
their work. The positions are available immediately in the Department of 
Structural Biochemistry (Director: Stefan Raunser) and are initially limited to 
3 years.

Summary:
Research projects in the Raunser lab focus on important biological questions 
concerning the structural organization of muscles, cytoskeletal proteins and 
bacterial toxin complexes. Our ultimate goal is to understand the mechanisms 
and structure-function relationship underlying these processes in health and 
disease in molecular detail. To this end, we employ single particle electron 
cryo-microscopy (cryo-EM), electron cryo-tomography (cryo-ET), X-ray 
crystallography, biochemical and biophysical methods and cell biology.
There are several projects available in our lab for talented and outstanding 
young researchers who are eager to combine these techniques to look deeper into 
cells and tissues in order to visualize and understand cellular components that 
have never been seen before.

Requirements:
Ideal PhD candidates should hold an excellent diploma or master degree in 
physics, biology, biochemistry, biophysics, or a related field of science.
Ideal PostDoc candidates should hold an excellent PhD in structural biology, 
biophysics, physics or in an equivalent area with previous experience in single 
particle cryo-EM or cryo-ET.
Strong written and oral communication skills in English are required.


Why join us?
Being a part of the community at the Max Planck Institute is more than just a 
job. Our dynamic research environment, distinct culture, and diverse community 
foster collaboration and excellence in every corner of science. We offer an 
extensive range of benefits and resources such as:

•   access to state-of-the-art research facilities

•   opportunities to collaborate on cutting-edge research

•   an international and exciting working atmosphere

•   an integrated training program that includes lectures, advanced 
scientific workshops, complementary skill courses and opportunities for career 
development

•   a mentoring program to guide and promote young scientists
PhD students will join the International Max Planck Research School for Living 
Matter (IMPRS-LM), which is a joint PhD Program between the Max Planck 
Institute of Molecular Physiology in Dortmund, the Technical University 
Dortmund, the Ruhr University Bochum and the University of Duisburg-Essen. All 
four institutions are located in the Ruhr Metropolitan Area of Germany, an 
extremely vibrant and culturally interconnected region.

Salary:
Payment of Postdocs depends on personal conditions and qualification according 
to the directive of the TVöD. Social benefits correspond to those of the public 
service. Employment of PhD students is according to the funding guidelines of 
the Max Planck Society.

How to Apply:
Applicants should submit a CV, a motivation letter outlining research 
experiences and interests and two reference letters by September 20th, 2020 to 
Stefan Raunser at 
raunser-jobsea...@mpi-dortmund.mpg.de

Additional Information:
The Max Planck Society (Max Planck Gesellschaft – MPG) is committed to 
increasing the number of individuals with disabilities in its workforce and 
therefore encourages applications from such qualified individuals. The MPG 
seeks to increase the number of women in those areas where they are 
underrepresented and therefore explicitly encourages women to apply. 
Furthermore, the MPG strives to foster an inclusive culture and diversity 
within its workforce. Therefore, all qualified applicants are encouraged to 
apply and will receive consideration for employment without regard to race, 
religion, color, national origin, age, sex, sexual orientation, disability 
status, or any other characteristic protected by applicable law.

---
Prof. Dr. Stefan Raunser | Director | Dep. Structural Biochemistry | Max Planck 
Institute of Molecular Physiology | Otto-Hahn-Straße 11, 44227 Dortmund, 
Germany | +49 231 133 2300




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bi

[ccp4bb] Closing Date Approaching: Protein Biochemist positions at Sosei Heptares

[Mathieu Rappas]

We are now seeking an experienced membrane protein biochemist to join the
Protein Expression and Biochemistry group at our research facility on
Granta Park, Cambridge, UK, working on membrane protein biochemical
characterisation to enable drug discovery efforts.

At Sosei Heptares we are equipped with state-of-the-art protein expression,
purification, SPR, mass-spec, crystallisation and cryoEM facilities.
Applicants should be proficient in the expression and purification of
challenging membrane proteins destined for biochemical, biophysical and
structural studies. A proven track record of publications related to the
expression, purification, and biochemical characterisation of difficult
membrane protein targets in peer-reviewed journals is highly desirable.

This is an exceptional opportunity to participate in pioneering science
with an Industry-leading Drug Discovery company.

The successful candidate is expected to:

   - Express and purify challenging membrane proteins
   - Perform appropriate quality control analyses and biochemically and
   biophysically characterise purified membrane proteins
   - Keep up to date, propose, develop, implement and optimise new
   techniques in the fields of membrane protein expression, purification and
   biochemical characterisation
   - Collaborate with other Sosei Heptares scientists on research projects,
   working closely with molecular biologists, biophysicists and structural
   biologists
   - Prepare and effectively present results (written and oral) to program
   teams

Have strong interpersonal skills and interact effectively with
collaborators across a wide range of disciplines
Requirements

   - Candidates should have or are about to obtain a PhD in biochemistry,
   biophysics or a related discipline
   - Possess extensive molecular biology skills and be knowledgeable in
   expression construct design and engineering
   - Proficient in the expression of membrane proteins from
   baculovirus/insect cells and/or mammalian cells
   - Proficient in the purification and extensive biochemical
   characterisation of membrane proteins
   - Familiar with the biochemical and biophysical techniques used to
   characterise proteins such as luminescence, fluorescence and FRET-based
   techniques
   - Candidates should understand the requirements of purified membrane
   proteins destined for structural (X-ray and/or CryoEM) and biophysical
   studies (SPR, mass spec)

Other information

*Applicants must be able to demonstrate proof of the right to work in the
United Kingdom.*

The successful candidate will be employed by Heptares Therapeutics Ltd, a
UK wholly owned subsidiary of Sosei Group Corporation.

We offer a competitive salary, commensurate with qualifications and
experience, and benefits package including pension and healthcare schemes.

Applications should include a covering letter, providing a short
description of the background to their interest in the role, with
curriculum vitae including the names and contact details for two referees.
Please apply through our on-line jobs portal with your application in pdf
format, quoting reference number 2020-5BMS.

*The closing date for applications is 4th September 2020*

Strictly No Agencies



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Webinars on CryoEM, HIV, SARS-CoV-2 at the Microbiology Virtual Week 2020

[H. Raaijmakers]

On Sept. 9 and 10 we sponsor 2 lectures at the Microbiology Virtual Week
2020.   

"_Using cryo-EM for designing next-gen therapeutics against HIV_" by
Dmitry Lyumkis, [1]PhD [1], Salk Institute 

* The basics of single-particle cryo-EM, including the latest
technical advances that are facilitating high-resolution structural
studies
* The biology of HIV integration, and why this step of the viral
lifecycle is vulnerable to inhibition
* How single-particle cryo-EM is becoming applicable to drug design
and helping to combat the global HIV epidemic

"_Structure-guided design of SARS-CoV-2 antivirals_" by Quan Wang, PhD
and Renhong Yan, PhD, ShanghaiTech and Westlake 

* Full-length ACE2 recognition by SARS-CoV-2
* RNA-dependent RNA polymerase nsp12 in complex with cofactors nsp7
and nsp8
* Design of Corona-targeting antiviral medicines

HIV Webinar - 9/9/2020 7:30-8:30am (PST) - 16:30h (CEST) - 23:30h (JST)
- Dr. Dmitry Lyumkis  

SARS-CoV-2 Webinar - 9/10/20 6-7am (PST) - 15:00h (CEST) - 22:00h (JST)-
Dr. Quan Wang and Dr. Renhong Yan  

https://www.labroots.com/virtual-event/microbiology-immunology-2020/agenda


Links:
--
[1]
https://www.labroots.com/virtual-event/microbiology-immunology-2020/speakers#dmitry_lyumkis



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/