[ccp4bb] Job opportunity in Berlin - HZB and Humboldt University advertise a postdoc position

[Manfred S. Weiss]

The Helmholtz Zentrum Berlin für Materialien und Energie, the 
Max-Delbrück-Center for Molecular Medicine, the Freie Universität Berlin, the 
Charite, the Max-Planck-Institute for Colloids and Interfaces  and the Humboldt 
Universität zu Berlin jointly operate three experimental stations for 
bio-macromolecular crystallography at BESSY II, Berlin's modern synchrotron 
radiation source, located in the lovely southeast of Berlin.

(https://www.helmholtz-berlin.de/forschung/oe/ps/macromolecular-crystallography/index_en.html)

The Humboldt University zu Berlin is seeking a

Post Doctoral Research Assistant

to work on and support research topics in the field of structural enzymology 
(e.g. control of chemical reactions in macromolecular crystals, combination of 
UV/Vis absorption spectroscopy and crystallography, etc.) originating from the 
group of Prof. Dr. Holger Dobbek. The successful candidate will also be 
involved in the operation of the BESSY II bio-macromolecular crystallography 
beamlines (headed by Dr. Manfred S. Weiss) including supporting external users 
at the beamlines and will take part in graduate student education.

Initially,  a contract lasting until 31.12.2023 will be offered to the 
successful candidate with the possibility for an extension. The salary will be 
based on German Federal TVöD. The position is available immediately.

Applicants should hold a Ph.D. in the biological, chemical or physical sciences 
and have a solid background in biochemical methods, in bio-macromolecular 
crystallography and/or related fields. The position also requires the 
documented ability to conduct independent research as well as excellent 
communication and interpersonal skills.

Please send applications (CV, list of publications, references, .pdf-file 
format) citing the reference number AN/073/22 in electronic form until 
28.04.2022 to:

Dr. Manfred Weiss 
(mswe...@helmholtz-berlin.de)

Here is the link to the job advertisement (in German):

https://www.personalabteilung.hu-berlin.de/de/stellenausschreibungen/wissenschaftliche-r-mitarbeiter-in-m-w-d-befristet-bis-31-12-2023-e-13-tv-l-hu






--
Dr. Manfred S. Weiss
Macromolecular Crystallography
Helmholtz-Zentrum Berlin
Albert-Einstein-Str. 15
D-12489 Berlin
Germany



Helmholtz-Zentrum Berlin für Materialien und Energie GmbH

Mitglied der Hermann von Helmholtz-Gemeinschaft Deutscher Forschungszentren e.V.

Aufsichtsrat: Vorsitzender Dr. Volkmar Dietz, stv. Vorsitzende Dr. Jutta 
Koch-Unterseher
Geschäftsführung: Prof. Dr. Bernd Rech, Thomas Frederking

Sitz Berlin, AG Charlottenburg, 89 HRB 5583

Postadresse:
Hahn-Meitner-Platz 1
14109 Berlin
Deutschland



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Job Posting - Senior Scientist I, Crystallographer position at AbbVie

[Tang, Henry Y]

Hi everyone,

I would like to draw your attention to the following Protein Crystallographer 
job position currently available within the Structural Biology Group at the 
AbbVie headquarters in Lake County, Illinois, USA. For details and to apply, 
please follow the link below:

https://careers.abbvie.com/abbvie/jobs/2206563?lang=en-us

Best regards,
Henry


Senior Scientist I, Phys Chem

Description
The Protein Crystallography Group at AbbVie Headquarters in Lake County, 
Illinois is seeking a highly motivated scientist to join our Structure-Based 
Drug Discovery team. The ideal candidate should have extensive hands-on 
experience in modern X-ray Crystallography techniques and computational methods 
of molecular structure analysis. As part of multidisciplinary teams, the 
Scientist will utilize fragment-based strategies to identify ligands and 
provide insight to advance drug discovery targets through structure-based 
design. The successful candidate will contribute to drug discovery projects 
across the portfolio of AbbVie interests that also include therapeutic 
antibodies and novel biologics.
Key Responsibilities:
* Determine X-ray crystal structures of protein-ligand complexes in 
high throughput modes and identify strategies for improved molecular designs.
* Provide guidance to crystallization and protein construct design 
efforts for useful sample preparations
* Utilize cheminformatics tools and manipulate scripts for use 
across mixed computing platforms
* Interact with members of Fragment-based Drug Discovery team to 
advance hit to lead projects
* Work with biologists, molecular modelers, and medicinal chemists 
to validate targets of interest
* Maintain accurate and timely records of experimental results
* Communicate results and interpretative analysis to project teams, 
and present at internal meetings
* Publish in peer-reviewed journals as appropriate and present at 
external scientific meetings
* Evaluate the scientific literature critically and adopt novel 
technologies which will facilitate structure-based drug discovery at AbbVie

Qualifications:
* PhD in Chemistry, Biochemistry, Biophysics, or a related field
* 3+ years of relevant academic or industry experience is required
* Proven ability in protein crystallization and crystal structure 
analysis with X-ray or cryo-EM/Electron Diffraction data
* Familiarity with structure-based drug design strategies and 
fragment based approaches
* Experience in complementary techniques of macromolecular SAXS 
analysis or cryo-EM is desirable
* Must be detail oriented and meticulous regarding documentation 
and data management
* Ability to work both independently and as part of a highly 
collaborative, interdisciplinary team
* Effective written and verbal communication skills
* Ability to work on multiple projects in parallel and rapidly 
adjust to changing priorities



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/