[ccp4bb] Postdoctoral position in cryoEM at the University of Toronto

[Walid Houry]

The Houry group at the University of Toronto is looking for an excellent 
postdoctoral fellow to study chaperone complexes using cryoEM.
Strong expertise in protein biochemistry and structural biology using cryoEM is 
a must.

For details contact:
Dr. Walid A. Houry, PhD
Department of Biochemistry, Temerty Faculty of Medicine
Department of Chemistry, Faculty of Arts and Science
University of Toronto
661 University Avenue
MaRS Centre, West Tower, Room 1612
Toronto, ON M5G 1M1
CANADA

Email walid.ho...@utoronto.ca
Web http://lab.walidhoury.com





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[ccp4bb] Postdoctoral position protein crystallography available at the Institute of Cancer Research, London UK

[Rob Van Montfort]

The Institute of Cancer Research (ICR), London, is one of the world’s most 
influential cancer research institutes, with an outstanding record of 
achievement dating back more than 100 years. We provided the first convincing 
evidence that DNA damage is the basic cause of cancer, laying the foundation 
for the now universally accepted idea that cancer is a genetic disease. Today, 
The ICR leads the world at isolating cancer-related genes and discovering new 
targeted drugs for personalised cancer treatment. Together with our hospital 
partner The Royal Marsden, we are rated in the top four centres for cancer 
research and treatment worldwide. As well as being a world-class institute, we 
are a college of the University of London. We came top in the league table of 
university research quality compiled from the Research Excellence Framework and 
second in 2021 (REF 2014 and 2021). The ICR is committed to attracting, 
developing and retaining the best minds in the world to join us in our mission 
– to make the discoveries that defeat cancer.

The Cancer Research UK Cancer Therapeutics Unit (CTU), within the Division of 
Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, 
comprising around 200 staff dedicated to the discovery and development of novel 
therapeutics for the treatment of cancer. The CTU’s exciting goal is to 
discover high quality small molecule drug candidates and to progress these to 
clinical trial. All the scientific disciplines are in place to make this 
possible, including medicinal chemistry, biology, structural biology, assay 
scientists, drug metabolism and clinical specialists. This is an exciting and 
fast-moving research setup and offers the opportunity to work within a 
multi-disciplinary environment using state-of-the-art techniques and equipment.

A postdoctoral position (ID263) is available in Dr Rob van Montfort’s Hit 
Discovery and Structural Design Team within the CTU. The Post-doc will be 
involved in the structure determination of proteins and protein/small molecule 
complexes by X-ray crystallography as part of one of the CTU’s drug discovery 
programmes. The post holder will be responsible for protein production and 
purification, protein crystallisation, structure determination by X-ray 
crystallography and subsequent structural analysis. The successful candidate 
will be an integral member of a multidisciplinary project team within the CTU 
at the ICR Sutton site, and will interact closely with biologists, 
computational chemists, medicinal chemists, assay scientists and structural 
biologists. The successful candidate will have access to state-of-the-art 
facilities for protein production and purification, as well as biophysical 
characterisation and crystallisation. We also benefit from excellent access to 
Diamond Light Source synchrotron at the Harwell Science and Innovation campus, 
Didcot, UK, for X-ray data collection. The postholder will be expected to work 
across the two sites in Chelsea, London and Sutton, Surrey. The starting salary 
will be in the range £38,607 to £42,534 p.a. inclusive (based on previous 
postdoctoral experience).

The post is offered on a fixed term contract of 2 years. Informal enquiries to 
rob.vanmontf...@icr.ac.uk or 
yann-vai.lebi...@icr.ac.uk.
Please DO NOT send your application to Dr van Montfort or Dr Le Bihan, but 
apply via the e-recruitment system on our website 
www.icr.ac.uk.
For more details see the following link:
https://jobs.icr.ac.uk/vacancies/263/postdoctoral-training-fellow--x-ray-crystallography-id263.html

Closing date:  21 June 2022


Dr. Rob van Montfort
Reader in Structural Biology and Cancer Drug Discovery
Team Leader Hit Discovery and Structural Design
Divisions of Cancer Therapeutics and Structural Biology
The Institute of Cancer Research
15 Cotswold Road
Sutton SM2 5NG
UK

Tel:
+44-(0)20-8722-4364
Email: rob.vanmontf...@icr.ac.uk


The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company 
Limited by Guarantee, Registered in England under Company No. 534147 with its 
Registered Office at 123 Old Brompton Road, London SW7 3RP.

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