Excellent idea.

From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Debanu Das 
<debanu....@gmail.com>
Date: Saturday, December 24, 2022 at 5:57 PM
To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK>
Subject: Re: [ccp4bb] Future Diffraction Methods
Consider merging with the Annual ACA meeting. The ACA meeting can also benefit 
from more X-ray diffraction methods rigor and training and it will help to 
elevate the continuity and history of the ACA and its previous and current 
member participation and contributions in the field.
Best,
Debanu

On Tue, Dec 20, 2022 at 6:40 PM Orville, Allen (DLSLtd,RAL,LSCI) 
<000066b6f959eb28-dmarc-requ...@jiscmail.ac.uk<mailto:000066b6f959eb28-dmarc-requ...@jiscmail.ac.uk>>
 wrote:
Hi,

Thanks James, for organising our last GRC meeting.

In the past few years, I’ve also attended one or more Annual BioXFEL 
International Conferences (open, but ending?) and Ringberg Workshop on Science 
with FELs (by invitation only). Both were excellent meetings held in the 
winter, complemented the GRC in diffraction methods, and benefited from 
relatively small attendance with very focused discussions.  I will also add 
that dynamic structural biology is a rapidly growing area that can include 
simultaneous functional, spectroscopic, and structural data collection from the 
same samples, and using synchrotron, XFEL, and/or electron sources. Moreover, 
many of the other life-science centric GRC’s also include significant 
structural data in their frontier programs and discussions (e.g. metals in 
biology, hemes and tetrapyrroles, enzymes, etc.). We are fundamental to 
biochemistry R&D… a broad community indeed.

AMO
~ ~ ~ ~ ~
Allen M. Orville, Ph.D.
Wellcome Investigator and Royal Society Wolfson Fellow
Principal Scientist, XFEL Hub at Diamond Light Source
Harwell Science and Innovation Campus
Didcot, Oxfordshire
OX11 0DE
United Kingdom

Phone: +44 (0) 1235 567505
Mobile: +44 (0) 7471 026061
email: allen.orvi...@diamond.ac.uk<mailto:allen.orvi...@diamond.ac.uk>

AMO site: https://www.diamond.ac.uk/Instruments/Mx/XFEL-Hub/Staff/Orville.html
XFEL-Hub site: https://www.diamond.ac.uk/Instruments/Mx/XFEL-Hub.html





From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK<mailto:CCP4BB@JISCMAIL.AC.UK>> 
on behalf of Frank von Delft 
<frank.vonde...@cmd.ox.ac.uk<mailto:frank.vonde...@cmd.ox.ac.uk>>
Date: Monday, 19 December 2022 at 09:22
To: CCP4BB@JISCMAIL.AC.UK<mailto:CCP4BB@JISCMAIL.AC.UK> 
<CCP4BB@JISCMAIL.AC.UK<mailto:CCP4BB@JISCMAIL.AC.UK>>
Subject: Re: [ccp4bb] Future Diffraction Methods
Shoot... that sucks.

Yes, we do need something!

"Structural Biology Methods"?


More interesting question:  does it need the GRC to host?  What about
reimagining the CCP4 study weekend - the question keeps coming up there
anyway.

That's one for CCP4 WG1 to discuss - they're meeting straight after New
Year, so maybe James, you and Ivo should hop on a zoom and kick the idea
around.

Frank



On 16/12/2022 22:10, James Holton wrote:
> I want to thank everyone who attended the 2022 Gordon Research
> Conference and Gordon Research Seminar on Diffraction Methods in
> Structural Biology, as well as all those who contributed to these
> great gatherings in the past.  It was an outstanding meeting if I do
> say so myself. Not just because it had been so long without in-person
> interaction, not just because we had zero covid cases (which I see as
> no small feat of Mind over Virus), but because of this amazing
> community. It is rare in this world to have such a strong spirit of
> collaboration, camaraderie and openness in undertakings as high-impact
> as this. Surmounting the barriers to atomic-detail imaging of
> biological systems has never been more exciting and more relevant.  I
> am proud to be a part of it, and honored to have served as Chair.
>
> It is therefore with heavy heart that I report to this community that
> I was the last Chair of the Diffraction Methods GRC.
>
> The GRC Conference Evaluation Committee
> (https://www.grc.org/about/conference-evaluation-committee/) voted
> this year to discontinue the Diffraction Methods GRC and GRS. This
> ends a 46-year tradition that I feel played a vital, and vibrant role
> in the work of the people who answer questions on this BB. The reason
> given was insufficient attendance.  All other metrics, such as
> evaluation surveys and demographics were very strong. I have tried to
> appeal, but I'm told the vote was unanimous and final. I understand
> that like so many conference organizing bodies the GRC is having to
> make tough financial decisions. I must say I disagree with this one,
> but it was not my decision to make.
>
> Many of the past and elected Chairs have been gathering and discussing
> how to replace the Diffraction Methods GRC/GRS going forward. Many
> great ideas, advice and perspectives have been provided, but that is a
> select group. I feel it is now time to open up this discussion to the
> broader community of structural methods developers and practitioners.
> There are some important questions to ask:
>
> * How do we define this community?
>         Yes, many of us do cryoEM too, but is that one methods
> meeting? or two?
> * Does this community need a new diffraction methods meeting?
>         As in one meeting or zero?
> * Should we merge with an existing meeting?
>         It would make logistics easier, but a typical GRC has 22 hours
> of in-depth presentations over 5 days.  The GRS is 7 hours over 2
> days. As Chair, I found that was not nearly enough.
> * Where do you think structural methods are going?
>         I think I know, but I may be biased.
> * Should the name change?
>         From 1976 to 2000, it was "Diffraction Methods in Molecular
> Biology". The word "diffraction", BTW, comes from the Latin for
> "shattering of rays", and originally used to describe the iridescence
> of bird feathers. That's spectroscopy!
> How about:
>  "Structural Methods for the Departing of Rays"
>
> I'm sure there are many more questions, and better suggestions.  I
> look forward to enlightening discussions!  GRCs have always been about
> discussion, and I hope to keep that tradition alive in this community.
>
> -James Holton
> MAD Scientist
>
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