[ccp4bb] Postdoctoral position in ion channel mechanism with cryo-EM available in the laboratory of Crina Nimigean at Weill Cornell Medical College in New York City
Postdoctoral position in ion channel mechanism with cryo-EM available in the laboratory of Crina Nimigean at Weill Cornell Medical College in New York City There is an availability in the laboratory of Crina Nimigean for an enthusiastic postdoc who is interested in the molecular workings of ion channels. The successful candidate will investigate ion channel structure and mechanism with single-particle cryo-EM and functional assays such as single-channel recordings, stopped-flow fluorescence, etc. The work in the lab is generally geared towards developing a mechanistic understanding of ion channels using functional and structural techniques (see two recent articles below). We are located at the Weill Cornell Medical College on the upper east side of Manhattan, within the vibrant and international tri-Institutional scientific community, which is comprised of Rockefeller University, Memorial Sloan Kettering and Weill Cornell. We have screening electron microscopes on site, within the newly established cryo-EM core facility at Cornell, and we have full access to state-of-the-art Titan Krios microscopes for high resolution data collection at the New York Structural Biology Center and other cost-based facilities. Qualifications and experience: Candidates should hold a Ph.D. and have a solid background in biophysics, ion channel electrophysiology, and/or protein biochemistry. Experience with cryo-EM is not required but welcome. Excellent verbal and written English communication skills, and ability to work in close collaboration with other researchers are required. Qualified applicants should send a cover letter, CV, and the names of three references by email to Crina Nimigean at crn2...@med.cornell.edu<mailto:crn2...@med.cornell.edu>. Rheinberger J., Gao X., Schmidpeter P.A.M., Nimigean C.M. (2018) Ligand discrimination and gating in CNG channels from apo and partial agonist-bound cryo-EM structures, eLife doi: 10.7554/eLife.39775 Marchesi A., Gao X., Adaixo R.., Rheinberger J., Stahlberg H., Nimigean C.M., Scheuring S. (2018) An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel, Nature communications, doi: 10.1038/s41467-018-06414-8 - Crina Nimigean, Ph.D. Weill Cornell Medical College Associate Professor of Physiology and Biophysics in Anesthesiology Associate Professor of Biochemistry http://physiology.med.cornell.edu/faculty/nimigean/lab/ Department of Anesthesiology, Box 124 525 East 68th Street, Room A-1050 New York, NY 10065 Phone: (212) 746 5947 Fax: (212) 746 4879 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Postdoctoral position in ion channel structure-function available in the laboratory of Crina Nimigean at Weill Cornell Medical College in New York City
Postdoctoral position in ion channel structure/function available in the laboratory of Crina Nimigean at Weill Cornell Medical College in New York City There is an availability in the laboratory of Crina Nimigean for an enthusiastic postdoc who is interested in the molecular workings of ion channels. The successful candidate will investigate ion channel structure and mechanism with single-particle cryo-EM and functional assays such as single-channel recordings, stopped-flow fluorescence, etc. The work in the lab is generally geared towards developing a mechanistic understanding of ion channels using functional and structural techniques. The ideal candidate for this position is an ion channel electrophysiologist/biochemist who wants to gain experience in cryo-EM. We are located at the Weill Cornell Medical College on the upper east side of Manhattan, within the vibrant and international tri-Institutional scientific community, which is comprised of Rockefeller University, Memorial Sloan Kettering and Weill Cornell. We have screening electron microscopes on site, within the newly established cryo-EM core facility at Cornell, and we have full access to state-of-the-art Titan Krios microscopes for high resolution data collection at the New York Structural Biology Center. Qualifications and experience: Candidates should hold a Ph.D. and have a solid background in biophysics, ion channel electrophysiology, and/or protein biochemistry. Experience with cryo-EM is thus not necessary. Excellent verbal and written English communication skills, and ability to work in close collaboration with other researchers are required. Qualified applicants should send a cover letter, CV, and the names of three references by email to Crina Nimigean at crn2...@med.cornell.edu<mailto:crn2...@med.cornell.edu>. - Crina Nimigean, Ph.D. Weill Cornell Medical College Associate Professor of Physiology and Biophysics in Anesthesiology Associate Professor of Biochemistry http://physiology.med.cornell.edu/faculty/nimigean/lab/ Department of Anesthesiology, Box 124 525 East 68th Street, Room A-1050 New York, NY 10065 Phone: (212) 746 5947 Fax: (212) 746 4879 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Postdoctoral position in ion channel structure with cryo-EM available immediately in the laboratory of Crina Nimigean at Weill Cornell Medical College in New York City
Dear all, We have an immediate availability in the lab for a postdoctoral position to investigate ion channel structure and mechanism with single-particle cryo-EM. The work in the lab is geared towards developing a mechanistic understanding of ion channels using functional and structural techniques. We are located at the Weill Cornell Medical College on the upper east side of Manhattan, within the vibrant and international tri-Institutional scientific community, which is comprised of Rockefeller University, Memorial Sloan Kettering and Weill Cornell. We have screening electron microscopes on site, within the newly established cryo-EM core facility at Cornell, and we have full access to state-of-the-art Titan Krios microscopes for high resolution data collection at the New York Structural Biology Center in Manhattan. Qualifications and experience: Candidates should hold a Ph.D. and have a solid background in biophysics, protein biochemistry, or structural biology. Experience with linux operating systems and command line interface is required. Experience with single-particle cryo-EM or other cryo-EM skills, as well as electron microscope operation is highly desirable. Excellent verbal and written English communication skills, and ability to work in close collaboration with other researchers are required. Qualified applicants should send a cover letter, CV, and the names of three references by email to Crina Nimigean at crn2...@med.cornell.edu<mailto:crn2...@med.cornell.edu>. Thank you, Crina Nimigean - Crina Nimigean, Ph.D. Weill Cornell Medical College Associate Professor of Physiology and Biophysics in Anesthesiology Associate Professor of Biochemistry http://physiology.med.cornell.edu/faculty/nimigean/lab/ Department of Anesthesiology, Box 124 525 East 68th Street, Room A-1050 New York, NY 10065 Phone: (212) 746 5947 Fax: (212) 746 4879
[ccp4bb] Postdoctoral positions available at Weill Cornell Medical College, New York, NY
Exciting research opportunities in the ion channel structure and mechanism area are available for two highly motivated post-doctoral fellows at the Weill Cornell Medical College in New York City, Department of Anesthesiology. The research focuses on analyzing ion channel function with electrophysiology and biochemistry as well as ion channel structure with X-ray crystallography. The goal of the work in the lab is to develop a mechanistic understanding of permeation, selectivity, and ligand gating in ion channels. More specifically, the projects involve investigation of the location of the gates in MthK potassium channels and the mechanism for ligand binding and activation in prokaryotic cyclic nucleotide-gated channels. More information about the lab can be found at: http://physiology.med.cornell.edu/faculty/nimigean/lab/ Qualifications and experience: Qualified candidates should have a Ph.D. degree and strong background in protein biochemistry and X-ray crystallography, and/or in ion channel electrophysiology. Excellent verbal and written English communication skills, and ability to work in close collaboration with other researchers are required. Qualified applicants should send a cover letter, CV, and the names of three references by email to Crina Nimigean at crn2...@med.cornell.edu. AA-EOE. - Crina Nimigean, Ph.D. Weill Cornell Medical College Associate Professor of Physiology and Biophysics in Anesthesiology Associate Professor of Biochemistry http://physiology.med.cornell.edu/faculty/nimigean/lab/ Department of Anesthesiology, Box 124 525 East 68th Street, Room A-1050 New York, NY 10065 Phone: (212) 746 5947 Fax: (212) 746 4879
[ccp4bb] please post
An exciting research opportunity in the ion channel structure and mechanism area is available for a highly motivated post-doctoral fellow at the Weill Medical College of Cornell University in New York City, Department of Anesthesiology. The research focuses on analyzing ion channel function with electrophysiology and biochemistry as well as ion channel structure with X-ray and electron crystallography. The goal of this work is to develop a mechanistic understanding of ligand gating in ion channels. Qualifications and experience: Qualified candidates should have a Ph.D. degree and strong background in either protein biochemistry and X-ray crystallography, or in ion channel electrophysiology. Excellent verbal and written English communication skills, and ability to work in close collaboration with other researchers are required. Qualified applicants should send a cover letter, CV, and the names of three references by email to Crina Nimigean at mailto:[EMAIL PROTECTED][EMAIL PROTECTED] Crina Nimigean, Ph.D. Assistant Professor of Physiology and Biophysics in Anesthesiology Assistant Professor of Biochemistry Weill Cornell Medical College Department of Anesthesiology, Box124 525 East 68th Street, Room A-1033 New York, NY 10065 Phone: (212) 746 5947 Fax: (212) 746 4879 http://physiology.ucdavis.edu/nimigean/
[ccp4bb] please post
An exciting research opportunity in the ion channel structure and mechanism area is available for a highly motivated post-doctoral fellow at the Weill Medical College of Cornell University in New York City, Department of Anesthesiology. The research focuses on analyzing ion channel function with electrophysiology and biochemistry as well as ion channel structure with X-ray and electron crystallography. The goal of this work is to develop a mechanistic understanding of ligand gating in ion channels. Qualifications and experience: Qualified candidates should have a Ph.D. degree and strong background in either protein biochemistry and X-ray crystallography, or in ion channel electrophysiology. Excellent verbal and written English communication skills, and ability to work in close collaboration with other researchers are required. Qualified applicants should send a cover letter, CV, and the names of three references by email to Crina Nimigean at mailto:[EMAIL PROTECTED][EMAIL PROTECTED] Crina Nimigean, Ph.D. Assistant Professor of Physiology and Biophysics in Anesthesiology Assistant Professor of Biochemistry Weill Cornell Medical College Department of Anesthesiology, Box124 525 East 68th Street, Room A-1033 New York, NY 10065 Phone: (212) 746 5947 Fax: (212) 746 4879 http://physiology.ucdavis.edu/nimigean/
