Re: [ccp4bb] CCP4 7.1 problems
I met a similar problem when I ran the "Geometry analysis" in coot-0.9. Coot
crashed with the following words. I had to roll back to ccp4-7.0. My system is
CentOS 7.
make_df_restraints_indices() 508
---
terminate called after throwing an instance of 'std::length_error'
what(): vector::_M_default_append
/usr/local/ccp4-7.1/bin/coot: line 333: 34362 Aborted (core
dumped) $coot_bin "$@"
;;; note: source file /usr/local/ccp4-7.1/share/guile/1.8/ice-9/boot-9.scm
;;; newer than compiled /usr/lib64/guile/2.0/ccache/ice-9/boot-9.go
Throw without catch before boot:
Throw to key syntax-error with args ("memoization" "In file ~S, line ~S: ~A
~S." ("/usr/local/ccp4-7.1/share/guile/1.8/ice-9/boot-9.scm" 101 "Bad define
placement" (define (toplevel-env? env) (or (not (pair? env)) (not (pair? (car
env)) #f)Aborting.
/usr/local/ccp4-7.1/bin/coot: line 333: 41050 Aborted (core
dumped) guile --version
failed to launch the crash catcher
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[ccp4bb] Job Opening: Group Leader of Structural Biology in Viva Biotech
Dear colleagues, Viva biotech is a leading CRO organization established in 2008 and located in Shanghai, China. As a customer-focused company with industry-leading capabilities, Viva provides structure-based drug discovery, biologics, and medicinal chemistry services to global pharmaceutical and biotech companies for their pre-clinical stage innovative drug development. Viva biotech is in a rapid expansion mode since its successful IPO in the Hong Kong Stock Exchange on May 9th, 2019. We now have openings for group leaders in structural biology and biochemistry. Anyone who is interested in the position, please send CV to h...@vivabiotech.com Job title: Group Leader in Structural Biology Job Description: We are seeking a highly motivated scientist to join our biology department as a protein group leader. Candidate will lead the structural biology team to carry out the biochemistry studies and gene-to-structure studies that elucidate the interactions between small molecules/peptides and their targets. The ideal candidate for this position must have the ability to handle multiple projects simultaneously in a fast-paced, dynamic and highly multi-tasking environment. Responsibility: 1. Manage multiple projects simultaneously and lead a group of scientists to achieve clients’ goals successfully. 2. Conceive, plan, design and implement a highly efficient project proposal and workflow to deliver fast turn-around results at client requested quality. 3. Demonstrate strong customer and service focus. Effectively collaborate with colleagues from different departments, collaborators and external clients or partners by active daily communication, telecom conference, etc. 4. Prepare and deliver presentations of project results to clients timely. 5. Provide scientifically sound guidance, resolve and promptly response to any issues, problems or challenges which may arise. 6. Identify and implement improvements to work processes. Qualifications: 1. The candidate should have a Ph.D. in Genetics, Molecular Biology, Biochemistry, Cell Biology or related field. 2. A minimum of 2 years of industry or academic relevant research experience is preferred. However, an outstanding Ph.D. graduate would be considered as well. 3. Have a proven track record in scientific achievement, including structural biology, illustrated in a list of publications. 4. Excellent organizational and communication skills are essential. 5. Working experience and/or in-depth knowledge in every step of protein crystallography which includes, but not limits to, bioinformatics, construct design, cloning, protein expression, purification, crystallization, X-ray data collection and processing, structure determination, modeling, and interpretation as well as common biophysical assay techniques, such as TSA, ITC, SPR, etc. 6. Strong written and verbal communication skills in both English and Chinese are mandatory. 7. Expertise in protein crystallization and crystal handing. 8. Experience with membrane protein production and crystallization is a plus. 9. Extensive data collection experiences at synchrotron. Able to lead a group of scientists to conduct data collection independently at synchrotron would be desired. 10. Proficient in structure biology related software, such as XDS and CCP4 is essential. 11. Demonstrated success in solving protein structures using MR method and experimental phasing. Working experience with SeMet-protein crystallization and structure determination with MAD or SAD method would be a plus. 12. The ability to analyze crystal structure, interpret, summarize, and present scientific results in a clear, concise, accurate manner to both clients and team members. 13. Experience in industry and/or with structure-based drug design is a plus. 14. Familiar with Linux system and working knowledge of system maintenance. A certain level of programming ability to increase work efficiency would be a big plus. 15. Demonstrated leadership in project management, experience with training junior would be a plus. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Job Opening: Group Leader of Structural Biology in Viva Biotech
Dear colleagues, Viva biotech is a leading CRO organization established in 2008 and located in Shanghai, China. As a customer-focused company with industry-leading capabilities, Viva provides structure-based drug discovery, biologics, and medicinal chemistry services to global pharmaceutical and biotech companies for their pre-clinical stage innovative drug development. Viva biotech is in a rapid expansion mode since its successful IPO in the Hong Kong Stock Exchange on May 9th, 2019. We now have openings for group leaders in structural biology and biochemistry. Anyone who is interested in the position, please send CV to h...@vivabiotech.com Job title: Group Leader in Structural Biology Job Description: We are seeking a highly motivated scientist to join our biology department as a protein group leader. Candidate will lead the structural biology team to carry out the biochemistry studies and gene-to-structure studies that elucidate the interactions between small molecules/peptides and their targets. The ideal candidate for this position must have the ability to handle multiple projects simultaneously in a fast-paced, dynamic and highly multi-tasking environment. Responsibility: 1. Manage multiple projects simultaneously and lead a group of scientists to achieve clients’ goals successfully. 2. Conceive, plan, design and implement a highly efficient project proposal and workflow to deliver fast turn-around results at client requested quality. 3. Demonstrate strong customer and service focus. Effectively collaborate with colleagues from different departments, collaborators and external clients or partners by active daily communication, telecom conference, etc. 4. Prepare and deliver presentations of project results to clients timely. 5. Provide scientifically sound guidance, resolve and promptly response to any issues, problems or challenges which may arise. 6. Identify and implement improvements to work processes. Qualifications: 1. The candidate should have a Ph.D. in Genetics, Molecular Biology, Biochemistry, Cell Biology or related field. 2. A minimum of 2 years of industry or academic relevant research experience is preferred. However, an outstanding Ph.D. graduate would be considered as well. 3. Have a proven track record in scientific achievement, including structural biology, illustrated in a list of publications. 4. Excellent organizational and communication skills are essential. 5. Working experience and/or in-depth knowledge in every step of protein crystallography which includes, but not limits to, bioinformatics, construct design, cloning, protein expression, purification, crystallization, X-ray data collection and processing, structure determination, modeling, and interpretation as well as common biophysical assay techniques, such as TSA, ITC, SPR, etc. 6. Strong written and verbal communication skills in both English and Chinese are mandatory. 7. Expertise in protein crystallization and crystal handing. 8. Experience with membrane protein production and crystallization is a plus. 9. Extensive data collection experiences at synchrotron. Able to lead a group of scientists to conduct data collection independently at synchrotron would be desired. 10. Proficient in structure biology related software, such as XDS and CCP4 is essential. 11. Demonstrated success in solving protein structures using MR method and experimental phasing. Working experience with SeMet-protein crystallization and structure determination with MAD or SAD method would be a plus. 12. The ability to analyze crystal structure, interpret, summarize, and present scientific results in a clear, concise, accurate manner to both clients and team members. 13. Experience in industry and/or with structure-based drug design is a plus. 14. Familiar with Linux system and working knowledge of system maintenance. A certain level of programming ability to increase work efficiency would be a big plus. 15. Demonstrated leadership in project management, experience with training junior would be a plus. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Job Opening: Senior Director or Executive Director Structural Biology and Biophysics
Job Title: Senior Director or Executive Director Structural Biology and Biophysics Viva biotech is a leading CRO organization supported by Angel investors and a US leading PE fund since 2008, located in Shanghai. China. Viva provides structure-based drug discovery, biologics and medicinal chemistry services to global pharmaceutical and biotech companies for their pre-clinical stage innovative drug development. Viva biotech is in a rapid expansion mode since its successful IPO on the Hong Kong Stock Exchange on May 9th, 2019. We have openings for senior director and executive director in structural biology and biochemistry. Anyone who is interested in the position, please send CV to h...@vivabiotech.com Job Description: We are seeking a highly motivated and innovative individual with strong working experiences in structure biology, biochemistry, as well as project management experience. The position will require leading multiple projects, working closely together with project managers and our partners to accomplish client goals successfully and timely. The candidate will be deeply involved in daily communications with clients and teammates via TC, emails and project meetings. The successful candidate is also required to build sustainable strong relationships with clients and external partners by active communications, professional conferences and on-site visits. Key Responsibility: The successful applicant will be responsible for the execution of the following tasks: • Provide leadership and expertise in structural biology, protein biochemistry, and biophysics. • Support and assist project managers in multiple projects of recombinant protein production, protein characterization and complex structure determination for activity-assay and structural studies. • Provide scientifically sound guidance, resolve and promptly response to any issues, problems or challenges which may arise. • Demonstrate strong customer and service focus. Able to thrive and deliver results in a fast paced, dynamic and highly multi-tasking environment. • Enable a positive team environment and interact with multi-disciplines project teams. • Lead a team of Cyro-EM including recruiting, on-boarding, coaching, business development, and performance management. • Understand and comply with company regulations, policies and SOPs, contribute to continuous improvement. • Candidate may periodically be asked to travel to different places in the US or Europe for business purpose and face-to-face meetings with clients. Required Qualifications: • Doctoral degree or equivalent in structural biology, biochemistry, biophysics or a related field with 10+ years of industry experience • A proven track record of scientific achievement illustrated in your list of publications • Broad knowledge in protein production, characterization, macro molecular crystallography, structural biology and biophysics • Years of working experience in managing projects from different targets with clear understanding of project needs and ensuring delivery of high-quality data with clear communication of timeline. • Demonstrated ability to be flexible and adaptable to changing business needs and client requirements. • Excellent written, verbal in both English and Chinese as well as interpersonal communication skills is a must. • Strong working knowledge or familiarity with biophysical methods techniques such as NMR, ITC, TSA, SPR, MST, etc would be a plus. • Broad experience or familiarity with different aspects of structure determination by Cryo-EM technology including sample preparation, data collection, data processing using state-of-art software, and 3-D reconstruction would be an additional advantage. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Job Offer: Group Leader in Structural Biology or Biochemistry
Dear colleagues, Viva Biotech, located in Shanghai, China, is specialized in structure-based drug discovery providing preclinical drug discovery research services to global pharmaceutical and biotech companies. We have opening for group leaders in structural biology and biochemistry. Anyone who is interested in the position, please send CV to h...@vivabiotech.com Job title: Group Leader in Structural Biology or Biochemistry Job description We are seeking highly motivated individuals with experience in protein biochemistry and structural biology. Candidates will lead the structural biology team to carry out the biochemistry studies and/or gene-to-structure studies which elucidate the interactions between small molecules/peptides and their targets. Experiences with protein expression and purification, excellent interpersonal and managerial skills, team player with excellent written and verbal communication skills and proficiency in structure biology related software. Excellent communication skill in English; 3-5 years working experiences with in US or Europe. Qualifications 1) Ph.D. in crystallography or protein biochemistry training with minimal 3-5 years’ working experience 2) Hands-on experience in protein crystallization, and protein expression and purification is optional. 3) Proficient in structure biology related software is plus. 4) Demonstrated managerial skill to guide groups through corporate change and growth. 5) Excellent verbal and writing skills in both English and Chinese are mandatory. 6) Strong communication skills and client interaction are required. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Job Offer: Group Leader in Structural Biology or Biochemistry
Dear colleagues, Viva Biotech, located in Shanghai, China, is specialized in structure-based drug discovery providing preclinical drug discovery research services to global pharmaceutical and biotech companies. We have opening for program leader in structural biology and biochemistry. Anyone who is interested in the position, please send CV to jin@vivabiotech.com. Job title: Group Leader in Structural Biology or Biochemistry Job description We are seeking a highly motivated individual with experience in protein biochemistry and structural biology. Candidates will lead the structural biology team to carry out the biochemistry studies and/or gene-to-structure studies which elucidate the interactions between small molecules/peptides and their targets. Experiences with protein expression and purification, excellent interpersonal and managerial skills, team player with excellent written and verbal communication skills and proficiency in structure biology related software. Excellent communication skill in English; 3-5 years working experiences with in US or Europe. Qualifications 1) Ph.D. in crystallography or protein biochemistry training with minimal 3-5 years’ working experience 2) Hands-on experience in protein crystallization, and protein expression and purification is optional. 3) Proficient in structure biology related software is plus. 4) Demonstrated managerial skill to guide groups through corporate change and growth. 5) Excellent verbal and writing skills in both English and Chinese are mandatory. 6) Strong communication skills and client interaction are required. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Job Offer: Group Leader in Structural biology or Biochemistry
Dear colleagues, Viva Biotech, located in Shanghai, China, is specialized in structure-based drug discovery providing preclinical drug discovery research services to global pharmaceutical and biotech companies. We have opening for group leader in structural biology and biochemistry. Anyone who is interested in the position please send CV to jin@vivabiotech.com. Job title: Group Leader in Structural Biology or Biochemistry Job description We are seeking a highly motivated individual with experience in protein biochemistry and structural biology. Candidates will lead the structural biology team to carry out the biochemistry studies and/or gene-to-structure studies which elucidate the interactions between small molecules/peptides and their targets. Experiences with protein expression and purification, excellent interpersonal and managerial skills, team player with excellent written and verbal communication skills and proficiency in structure biology related software. Excellent communication skill in English; 3-5 years working experiences with in US or Europe. Qualifications 1) Ph.D. in crystallography or protein biochemistry training with minimal 3-5 years’ working experience 2) Hands-on experience in protein crystallization, and protein expression and purification is optional. 3) Proficient in structure biology related software is plus. 4) Demonstrated managerial skill to guide groups through corporate change and growth. 5) Excellent verbal and writing skills in English are essential. 6) Strong communication skills and client interaction are required. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Job Offer: Group Leader in Structural biology or Biochemistry
Dear colleagues, Viva Biotech, located in Shanghai, China, is specialized in structure-based drug discovery providing preclinical drug discovery research services to global pharmaceutical and biotech companies. We have opening for program leader in structural biology and biochemistry. Anyone who is interested in the position please send CV to jin@vivabiotech.com. Job title: Group Leader in Structural Biology or Biochemistry Job description We are seeking a highly motivated individual with experience in protein biochemistry and structural biology. Candidates will lead the structural biology team to carry out the biochemistry studies and/or gene-to-structure studies which elucidate the interactions between small molecules/peptides and their targets. Experiences with protein expression and purification, excellent interpersonal and managerial skills, team player with excellent written and verbal communication skills and proficiency in structure biology related software. Excellent communication skill in English; 3-5 years working experiences with in US or Europe. Qualifications 1) Ph.D. in crystallography or protein biochemistry training with minimal 3-5 years’ working experience 2) Hands-on experience in protein crystallization, and protein expression and purification is optional. 3) Proficient in structure biology related software is plus. 4) Demonstrated managerial skill to guide groups through corporate change and growth. 5) Excellent verbal and writing skills in English are essential. 6) Strong communication skills and client interaction are required. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
