[ccp4bb] message for CCP4bb

2010-10-25 Thread Frank Kozielski
Dear all,

Can you please post the message below to the CCP4bb.

Thank you very much in advance 

Best wishes

Frank





The Beatson Institute for Cancer Research
Postdoctoral Scientist – Protein Crystallography
Salary from £25,500 – £38,000 (Depending on experience)

3 year fixed term contract.

The Beatson Institute in Glasgow is one of Europe's leading cancer research 
centres. It is core funded by Cancer Research UK and supports cutting edge 
research on the molecular mechanisms of cancer development. The Institute 
provides an outstanding research environment, underpinned by state-of-the art 
core services and advanced technologies. 

We are seeking an experienced protein crystallographer to investigate the 
structures of cancer-related proteins. Our group is particularly interested in 
members of the kinesin superfamily with a focus on human mitotic kinesins and 
their associated proteins. Several of these proteins are good targets for drug 
development in cancer chemotherapy. In addition, we strongly collaborate with 
other groups at the Institute to determine structures of different types of 
proteins involved in cancer development.

We have a well-equipped laboratory for all aspects of structural work including 
ÄKTA protein purification systems, a Mosquito nano-drop robot, automated 
storage and visualisation systems (Formulatrix at 4°C and 19°C), and a Rigaku 
HighFlux Homelab microfocus diffraction system. In addition, we are well 
equipped to characterise the biochemistry of protein - inhibitor complexes 
towards the optimisation of lead compounds in collaboration with our chemistry 
colleagues. For more details please refer to our web site at 
http://www.beatson.gla.ac.uk/Regulation-of-Cancer-Cell-Proliferation-and-Growth/Frank-Kozielski-Molecular-Motors.html

The successful applicant must hold a PhD in protein crystallography and have 
successfully completed at least one post-doctoral position in the same field. A 
good theoretical background in protein crystallography and extensive experience 
in the determination of protein structures will be strongly favoured. 
Experience with eukaryotic expression systems would be an advantage.

Applications with CV and names of two referees should be sent to Prof. Frank 
Kozielski, The Beatson Institute for Cancer Research, Garscube Estate, 
Switchback Road, Bearsden, Glasgow, G61 1BD, Scotland (FAX: +44 141 942 3653) 
or by Email to f.koziel...@beatson.gla.ac.uk.



[ccp4bb] job advert

2008-11-27 Thread Frank Kozielski
thank you for posting the message below to the ccp4bb
Frank


The Beatson Institute for Cancer Research

Postdoctoral Scientist – Protein Crystallography

Salary from £25,500 – £38,000 (Depending on experience)

3 year fixed term contract

The Beatson Institute in Glasgow is one of Europe's leading cancer research 
centres. It is core funded by Cancer Research UK and supports cutting edge 
research into the molecular mechanisms of cancer development. The Institute has 
recently moved to a new facility that provides an outstanding research 
environment, underpinned by state-of-the art core services and advanced 
technologies. 

We are seeking an experienced protein crystallographer to investigate the 
structure of cancer-related proteins, to work in a recently established 
research group interested in the kinesin superfamily with a focus on human 
mitotic kinesins and their associated proteins. Many of these proteins are good 
targets for drug development in cancer chemotherapy. In addition, we 
collaborate with other groups at the Institute to determine the structures of 
cancer-related proteins.

We have a well-equipped laboratory for all aspects of structural work including 
ÄKTA protein purification systems, a Mosquito nano-drop robot, an automated 
storage and visualisation system (Formulatrix), and a Rigaku HighFlux Homelab 
microfocus diffraction system. In addition, we are well equipped to 
characterise the biochemistry of protein - inhibitor complexes towards the 
optimisation of lead compounds in collaboration with our chemistry colleagues.  
 For more details please refer to our web site at 
http://www.beatson.gla.ac.uk/Regulation-of-Cancer-Cell-Proliferation-and-Growth/Frank-Kozielski-Molecular-Motors.html

The successful applicant must hold a PhD in protein crystallography and have 
successfully completed at least one post-doctoral position in the same field. A 
good theoretical background in protein crystallography and extensive experience 
in the determination of protein structures will be strongly favoured.

Applications with CV and names of two referees should be sent to Prof. Frank 
Kozielski, The Beatson Institute for Cancer Research, Garscube Estate, 
Switchback Road, Bearsden, Glasgow, G61 1BD, Scotland (FAX: +44 141 942 3653) 
or by Email to [EMAIL PROTECTED]



[ccp4bb] Postdoctoral Position in Protein Crystallography at the Beatson Institute for Cancer Research, Glasgow

2008-10-07 Thread Frank Kozielski
Postdoctoral Position in Protein Crystallography at the Beatson Institute for 
Cancer Research, Glasgow

 

We are seeking an experienced postdoctoral researcher to investigate the 
structure of cancer related proteins and drug targets.

 

We are a newly established group at the Beatson Institute for Cancer Research 
in Glasgow, UK. Our group is interested in the kinesin superfamily with a focus 
on human mitotic kinesins and their associated proteins. Many of these proteins 
are good targets for drug development in cancer chemotherapy. In addition, we 
collaborate with other groups at the Institute to determine the structures of 
cancer-related proteins.

 

We have a well-equipped state-of-the-art laboratory for all aspects of 
structural work including ÄKTA protein purification systems, a Mosquito 
nano-drop robot for protein crystallisation, an automated storage and 
visualisation system (Formulatrix), and a Rigaku HighFlux Homelab microfocus 
diffraction system. In addition, we are well equipped to characterise the 
biochemistry of protein - inhibitor complexes towards the optimisation of lead 
compounds in collaboration with our chemistry colleagues.  The Beatson 
Institute has a large range of core service facilities including DNA 
sequencing, protein production (E. coli and Baculovirus) and mass spectrometry.

 

Applicants must hold a PhD in structural biology with a strong background in 
protein crystallography. Experience in protein expression, purification and the 
determination of x-ray crystal structures of proteins would be strongly 
favoured.

 

The position is available for 3 years with the possibility of an extension for 
a further 2 years. 

 

 

Closure date: 31-10-2008

 

Applications for the above post with CV and names of three referees should be 
send by email to:

 

Prof. Frank Kozielski

The Beatson Institute for Cancer Research

Switchback Road, Bearsden

Glasgow G61 1BD

Scotland

Email: [EMAIL PROTECTED]

http://www.beatson.gla.ac.uk/Regulation-of-Cancer-Cell-Proliferation-and-Growth/Frank-Kozielski-Molecular-Motors.html



[ccp4bb] Postdoctoral positions in Protein Crystallography, Glasgow

2008-01-28 Thread Frank Kozielski
Postdoctoral Positions in Protein Crystallography at the Beatson Institute for 
Cancer Research, Glasgow

 

We are seeking several highly motivated postdoctoral researchers to investigate 
the structure of cancer related proteins and drug targets.

 

We are a newly established group at the Beatson Institute for Cancer Research 
in Glasgow, UK. Our group is interested in proteins of the kinesin superfamily, 
and their associated proteins, with a focus on human mitotic kinesins. Many of 
these proteins are good candidates for drug development in cancer chemotherapy. 
In addition, we will also determine the structures of other cancer-related 
proteins in collaboration with other groups in the Institute.

 

We have a new, fully equipped and state-of-the-art structural biology 
laboratory including ÄKTA protein purification systems, nano- and micro-drop 
robots for automated protein crystallization, a Rigaku HighFlux Homelab 
microfocus diffraction system and comprehensive data processing facilities. In 
addition, we are well equipped to characterise the biochemistry of protein - 
inhibitor complexes towards the optimisation of lead compounds in collaboration 
with our chemist colleagues.  The Beatson Institute has a large range of core 
service facilities including DNA sequencing, protein production and mass 
spectrometry.

 

A number of positions are available (3 year contract in the first instance):  

 

1) We require researchers with significant experience in protein 
crystallisation and structure determination and who are fully familiar with all 
the major software packages for x-ray crystallography.  

 

2) An additional post is available for a biochemist with experience of 
characterising protein-inhibitor complexes. Experience in data processing, 
structure solution and model building is required. 

 

3) The third position requires experience in cloning, expression and 
purification of proteins. The successful candidate is expected to actively 
participate in structure determination. Experience of crystallisation robots is 
an advantage but not essential.

 

Closing date for applications is 22nd Feb 2008.  Applications, with CV and 
names of three referees, should be sent by email to:

 

Prof. Frank Kozielski

The Beatson Institute for Cancer Research

Switchback Road, Bearsden

Glasgow G61 1BD

Scotland

Email: [EMAIL PROTECTED] mailto:[EMAIL PROTECTED] 

http://www.beatson.gla.ac.uk/research/index.html?topic_id=544