[ccp4bb] Structural Biology activities at the ESRF User meeting 2024
Dear CCP4ers, The ESRF User Meeting for 2024 is scheduled to be held onsite from 5th to 7th February. https://www.esrf.fr/home/events/conferences/2024/user-meeting-2024.html This edition includes three Tutorials related to Structural Biology: - Monday 5th, 9:00 - 12:30 (hybrid event): The Structural Biology BAG meeting. Presentation of information and updates concerning the Structural Biology beamlines, exchange between the beamline scientists and the User Community. - Monday 5th, 14:00 - 16:00 or 16:00 - 18:00: Meet the Structural Biologist Group scientists on the beamlines. Discussions and demos on ID29-EBSL8, icOS, ID23-1, ID23-2, ID30A-1, ID30A-3 and ID30B. - Monday 5th, 14:00 - 16:00 (hybrid event): Demystifying the Structure-to-Solution (SOS) pipeline: a comprehensive tutorial on its current components. A tutorial to harness the power of high-resolution cryo-EM. And a User-Dedicated Microsymposium on Serial Crystallography: - Wednesday 7th, 8:30 – 18:00: Towards filming macromolecular movies at the ESRF-EBS. This symposium aims to present the new science being tackled with serial and classic crystallography at 4th generation synchrotron, and take the opportunity to bring together both expert and non-expert users to discuss and promote the different methods to highlight structural dynamics. The event combines keynote presentations and invited contributions from submitted abstracts. Keynote speakers: Gisela Brändén, University of Gothenburg, Sweden Gerhard Hofer, Stockholm University, Sweden José Manuel Martin Garcia, IQF-BC CSIC Madrid, Spain Henrike Müller-Werkmeister, University of Potsdam, Germany Kara Zielinski, Cornell University, USA Full programme can be found here: https://www.esrf.fr/files/live/sites/www/files/events/conferences/2024/User%20Meeting/UDMS/UDM1/UDM1-2024_Programme.pdf The registration for the ESRF User meeting and satellite microsymposia is open until 15th January. We look forward to seeing you at the meeting! Best wishes, montse -- MontseSOLER LOPEZ Head of the Structural Biology Group European Synchrotron Radiation Facility 71 Avenue des Martyrs – CS 40220 F-38043 Grenoble Cedex 09 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] Postdoctoral position in Structural Biology of Lysine methylation and Cancer in Grenoble
Dear all, on behalf of Jan Kadlec from the Institute of Structural Biology (IBS) in Grenoble, France: POSTDOCTORAL POSITION IN STRUCTURAL BIOLOGY OF LYSINE METHYLATION AND CANCER IN GRENOBLE A 2-year post-doctoral position is available in the laboratory of Jan Kadlec at the Institut de Biologie Structurale (IBS) in Grenoble, France The project is focused on structural and biophysical characterization of non-histone targets of lysine methyltransferases involved in cancer development. The aim is to understand the mechanism by which the methylation of these new substrates causes cancer to eventually develop novel anti-cancer therapeutics. The project will be carried out in collaboration with the Reynoird team (IAB Grenoble, nicolas.reyno...@univ-grenoble-alpes.fr,), expert in lysine methylation signaling (see Reynoird et al., Genes Dev. [1] 2016 and Mazur*, Reynoird* et al. Nature. 2014). Another 2-year postdoc position in lysine signalling is avalilable in his lab and both postdocs will work together on different aspects of the project. Our group is specialized in structural analysis of epigenetic regulators. We use an interdisciplinary approach combining structural biology (X-ray crystallography, EM, NMR), biochemistry, cell biology and mass spectrometry. The IBS is a member of the Partnership for Structural Biology (www.psb-grenoble.eu [2]) providing access to integrated state-of-the-art structural biology technologies, including ESRF synchrotron X-ray beamlines for MX and SAXS, cryo-EM/tomography and NMR as well as biophysics, confocal microscopy and high-throughput crystallization platforms. The successful candidate will be highly motivated and have recently acquired a PhD in the field of biochemistry/structural biology. Skills in protein sample preparation methods (protein expression and purification) are required and experience in protein crystallography would be an advantage. Preferable start: June 2020. Informal inquiries and applications including CV and names of two possible referees can be sent directly to Jan Kadlec (jan.kad...@ibs.fr) by May 1st. Links: -- [1] https://www.ncbi.nlm.nih.gov/pubmed/26988419 [2] http://www.psb-grenoble.eu To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
[ccp4bb] PhD position in structural biology at the European Synchrotron, Grenoble
Dear all, A PhD position is available in our laboratory at the European Synchrotron in Grenoble, within the InnovaXN Horizon 2020 MSCA COFUND programme. We are looking for a highly motivated student to work on enzymes of melanogenesis as targets for developing efficient compounds to treat pigmentation disorders. In partnership with the biotech company ImmuSmol in Bordeaux, the project involves production and profiling of specific antibodies against melanin pathway metabolites, protein expression and purification of tyrosinase enzymes, biochemical and biophysical assays, and structure determination by crystallography. Candidates with a background in chemistry or life sciences and a strong interest in structural biology are encouraged to apply. More details and application instructions are here: https://esrf.gestmax.eu/1397/1/phd-position-structural-basis-of-melanogenesis-enzymes/en_US Deadline: 31 March 2020 InnovaXN web site: https://www.innovaxn.eu/programme-partners/ ESRF web site: http://www.esrf.eu/ ImmuSmol web site: https://www.immusmol.com/ Feel free to contact me for informal inquiries. Best regards, Montse -- Montse SOLER LOPEZ European Synchrotron Radiation Facility Structural Biology Group Carl-Ivar Branden Building - office 114 71 Avenue des Martyrs – CS 40220 F-38043 Grenoble Cedex 09 Phone: +33 (0)47688 1770 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
[ccp4bb] LIVESTREAMING: Cryo-EM Symposium, 6-7 July 2017, Grenoble, France
Dear colleagues, onJuly6th and 7th, the European Photon & Neutron Campus in Grenoblewill host a unique CRYO-EM Symposium in the framework of the newly established cryo-EM platform. The new facility will be open to the user community based on peer-review of scientific merit and technical feasibility. Scientists from ESRF, IBS and EMBL will support user operation. Registration for the event is now closed, but you can follow the talks, presented by worldwide experts in the field, through YouTube live streaming: https://www.youtube.com/user/LightforScience We will be live from 1.30pm on 6 July 2017. Check out the programme here: http://www.esrf.eu/cryo-em.fr On behalf of the Organising committee: Stephen Cusack (EMBL), Trevor Forsyth (ILL/Keele), Wojciech Galej (EMBL), Gordon Leonard (ESRF), Marco Marcia (EMBL), Christoph Mueller-Dieckmann (ESRF), Hugues Nury (IBS), Guy Schoehn (IBS), Montserrat Soler-Lopez (ESRF), Jean Susini (ESRF) and Winfried Weissenhorn (IBS).
[ccp4bb] SECOND ANNOUNCEMENT: Cryo-EM Symposium, 6-7 July 2017, European Photon & Neutron Campus, Grenoble, France
Dear all, This is the second announcement to the Cryo-Electron Microscopy Symposium that will take place from 6-7th July, 2017 in Grenoble, France. The aim of this symposium is to promote the exciting opportunities in structural biology opened by the advances in cryo-electron microscopy and by the integration of structural biology approaches at multi-resolution level. This symposium will celebrate the establishment of a new cryo-EM platform on the EPN campus. The platform will offer access to the international structural biology community to a new Titan Krios equipped with a Quantum LS filter and phase plate. Such microscope will be installed as a user facility at the ESRF and will reinforce the ongoing EM activity at the IBS and at the EMBL. The new facility will thus be open to the user community based on peer-review of scientific merit and technical feasibility. Scientists from ESRF, IBS and EMBL will support user operation. The symposium will bring together leading experts, junior researchers and representatives of industrial partners to present and discuss the latest developments and the future trends in cryo-EM as well as their applications in addressing biological challenges. It will also provide a forum for discussion among both established and junior scientists from different disciplines. We encourage participants to present their scientific results in a poster session, with the possibility of being selected for a short talk. Poster Abstract submission deadline: 30 April 2017; Notification of acceptance: 15 May 2017 *Deadline for registration: 22 May 2017* You can find more information at: http://www.esrf.fr/cryo-em.fr We look forward to seeing you in Grenoble! On behalf of the Organising committee: Stephen Cusack (EMBL), Trevor Forsyth (ILL/Keele), Wojciech Galej (EMBL), Gordon Leonard (ESRF), Marco Marcia (EMBL), Christoph Mueller-Dieckmann (ESRF), Hugues Nury (IBS), Guy Schoehn (IBS), Montserrat Soler-Lopez (ESRF), Jean Susini (ESRF) and Winfried Weissenhorn (IBS). -- MontseSOLER LOPEZ European Synchrotron Radiation Facility Structural Biology Group Carl-Ivar Branden Building - office 114 71 Avenue des Martyrs – CS 40220 F-38043 Grenoble Cedex 09 Phone: +33 (0)47688 1770 Fax:+33 (0)47620 9400
[ccp4bb] Cryo-EM Symposium, 6-7 July 2017, European Photon & Neutron Campus, Grenoble, France
Dear all, We are pleased to announce the Cryo-Electron Microscopy Symposium that will take place from 6-7th July, 2017 in Grenoble, France. The aim of this symposium is to promote the exciting opportunities in structural biology opened by the advances in cryo-electron microscopy and by the integration of structural biology approaches at multi-resolution level. This symposium will celebrate the establishment of a new cryo-EM platform on the EPN campus. The platform will offer access to the international structural biology community to a new Titan Krios equipped with a Quantum LS filter and phase plate. Such microscope will be installed as a user facility at the ESRF and will reinforce the ongoing EM activity at the IBS and at the EMBL. The new facility will thus be open to the user community based on peer-review of scientific merit and technical feasibility. Scientists from ESRF, IBS and EMBL will support user operation. The symposium will bring together leading experts, junior researchers and representatives of industrial partners to present and discuss the latest developments and the future trends in cryo-EM as well as their applications in addressing biological challenges. It will also provide a forum for discussion among both established and junior scientists from different disciplines. We encourage participants to present their scientific results in a poster session, with the possibility of being selected for a short talk. Due to limited attendance (maximum of 80 external participants), early registration is encouraged. More information can be found at: http://www.esrf.fr/cryo-em.fr We look forward to seeing you in Grenoble! On behalf of the Organising committee: Stephen Cusack (EMBL), Trevor Forsyth (ILL/Keele), Wojciech Galej (EMBL), Gordon Leonard (ESRF), Marco Marcia (EMBL), Christoph Mueller-Dieckmann (ESRF), Hugues Nury (IBS), Guy Schoehn (IBS), Montserrat Soler-Lopez (ESRF), Jean Susini (ESRF) and Winfried Weissenhorn (IBS). -- MontseSOLER LOPEZ, PhD European Synchrotron Radiation Facility Structural Biology Group Carl-Ivar Branden Building - office 114 71 Avenue des Martyrs – CS 40220 F-38043 Grenoble Cedex 09 Phone: +33 (0)47688 1770 Fax:+33 (0)47620 9400
