[ccp4bb] Post-Doctoral Position at the University of Illinois to Study Ribosome Structure

[Yury Polikanov]

*Post-Doctoral Position in Structural Biology at the University of Illinois
at Chicago (UIC) to Study the Structure and Function of the Ribosome*

The Polikanov Laboratory at the University of Illinois at Chicago (IL, USA) is
looking for a talented, skillful, and highly motivated researcher to fill
the available *NIH-funded Post-Doctoral Scholar *position to study the
structure and function of the bacterial ribosome.

The research in the Polikanov Laboratory is focused on understanding the
basic principles of protein synthesis in bacteria, the modes of action of
ribosome-targeting antibiotics, and the mechanisms of drug resistance at a
structural level. More information about Dr. Polikanov research can be
obtained from the most recent publications
(*https://www.ncbi.nlm.nih.gov/sites/myncbi/yury.polikanov.1/bibliography/50395623/public/?sort=date&direction=descending
<https://www.ncbi.nlm.nih.gov/sites/myncbi/yury.polikanov.1/bibliography/50395623/public/?sort=date&direction=descending>*)
or found on the web-page (https://bios.uic.edu/bios/people/faculty/yury-
polikanov). The successful candidate will be involved in the determination
of high-resolution structures of ribosome functional complexes with various
protein translation factors, tRNAs, and antibiotics using macromolecular
X-ray crystallography and potentially cryo-EM techniques.

*Basic qualifications:*

   - PhD in chemistry, biochemistry
   ,
   biophysics,
   or a related field;
   - Practical skills with the most standard methods currently used in
   molecular biology, and biochemistry (such as protein expression,
   purification);
   - Experience in structural biology (X-ray crystallography or cryo-EM);
   - Experience in the RNA biology field is not required but highly desired;

*The successful candidate is also expected to:*


   - Act independently in terms of planning and executing the experiments;
   - Compile, analyze, and prepare data for publications;
   - Assist with training of graduate and undergraduate students.


Review of applications will begin immediately and will continue until the
position is filled. Interested candidates should apply by 04/16/2021 using
the following link:
https://jobs.uic.edu/job-board/job-details?jobID=142760
or email directly to Dr. Polikanov - yu...@uic.edu.
Please make sure to include CV, cover letter, and contact information for
three references. *For full consideration, in **the cover letter,
describe** how your previous
research accomplishments and scientific interests fit with the scope of the
research in the Polikanov research group.*

*The University of Illinois at Chicago is an Equal Opportunity, Affirmative
Action employer. Minorities, women, veterans, and individuals with
disabilities are encouraged to apply.*

*Offers of employment by the University of Illinois may be subject to
approval by the University’s Board of Trustees and are made contingent upon
the candidate’s successful completion of any criminal background checks and
other pre-employment assessments that may be required for the position
being offered. Additional information regarding such pre-employment checks
and assessments may be provided as applicable during the hiring process.*

*The University of Illinois System requires candidates selected for hire to
disclose any documented finding of sexual misconduct or sexual harassment
and to authorize inquiries to current and former employers regarding
findings of sexual misconduct or sexual harassment. For more information,
visit **https://www.hr.uillinois.edu/cms/One.aspx?portalId=4292&pageId=1411899
<https://www.hr.uillinois.edu/cms/One.aspx?portalId=4292&pageId=1411899>*



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[ccp4bb] ​Visiting Research Specialist Position | Polikanov Lab | University of Illinois at Chicago

[Yury Polikanov]

The Polikanov Lab is seeking a Visiting Research Specialist. The
successful candidate will conduct research by using X-ray crystallography
techniques to obtain a structural basis for various functions of the
bacterial ribosome and its inhibition by different small-molecule
inhibitors. The successful candidate should have a strong theoretical
background in standard biochemical, molecular biology, and biophysical
methods, as well as practical skills in the most standard methods currently
used in molecular biology and biochemistry (such as protein expression,
purification, etc.). Knowledge in X-ray crystallography or other structural
techniques is desired but not required. Expert-level knowledge of the
programming languages (such as Python) is highly desirable.

The successful candidate would conduct his own research and assist with the
principal investigator’s research while training other laboratory personnel
in various techniques, experiments, and the appropriate use of research
equipment. He/She would also perform data analysis and manage, document,
and help with the dissemination of research activities for publication and
outreach.

*Duties:*
• Perform research relevant to the assigned projects;
• Isolate and crystallize bacterial ribosomes;
• Purify all additional components necessary for the crystallization
experiments, such as recombinant proteins, tRNAs;
• Collect X-ray diffraction data from the ribosome crystals at the APS
Synchrotron;
• Perform data analysis; coordinate, analyze, and document results for
publication;
• Directly participate in writing papers and grants based on the
experimental data;
• Train undergraduate and graduate students in research methods, use of
equipment, record keeping, and laboratory database entry;
• Attend weekly group meetings and journal clubs.

*Minimum qualifications:*
• Bachelor’s degree in chemistry, biochemistry, biophysics, or a related
field;
• Master’s degree or higher is preferred;
• Minimum 3 years of laboratory research experience;
• Strong background in biochemistry and molecular biology;
• Practical skills with the most standard methods currently used in
molecular biology, and biochemistry (such as protein expression,
purification);
• Experience in structural biology (cryo-EM or X-ray crystallography) is
desired;
• Experience in RNA biology is desired.
• The successful candidate should be able to walk into the laboratory and
be able to start working without significant additional training in basic
molecular biology techniques.

*For fullest consideration, interested candidates should submit an
application, including CV, cover letter, and contact information for three
references at https://jobs.uic.edu/job-board/job-details?jobID=149023
<https://jobs.uic.edu/job-board/job-details?jobID=149023> by August 9,
2021. Questions can be directed to Dr. Polikanov at yu...@uic.edu
. **In the cover letter, describe what your scientific
interests are and how your previous research accomplishments and scientific
interests fit with the scope of the research in the Polikanov research
group.*



*The University of Illinois at Chicago is an Equal Opportunity, Affirmative
Action employer including Disability/Vets.*


*Offers of employment by the University of Illinois may be subject to
approval by the University’s Board of Trustees and are made contingent upon
the candidate’s successful completion of any criminal background checks and
other pre-employment assessments that may be required for the position
being offered. Additional information regarding such pre-employment checks
and assessments may be provided as applicable during the hiring process.*
*The University of Illinois System requires candidates selected for hire to
disclose any documented finding of sexual misconduct or sexual harassment
and to authorize inquiries to current and former employers regarding
findings of sexual misconduct or sexual harassment. For more information,
visit https://www.hr.uillinois.edu/cms/One.aspx
<https://www.hr.uillinois.edu/cms/One.aspx>? portalId=4292&pageId=1411899*

-- 
------
Yury Polikanov, Ph.D.
Associate Professor
Department of Biological Sciences
College of Liberal Arts and Sciences
University of Illinois at Chicago
900 South Ashland Avenue, MBRB 4170
Chicago, IL 60607
Tel: 1-312-413-2408 (Office)
Tel: 1-312-355-0463 (Laboratory)
Fax: 1-312-413-2691
E-mail: yu...@uic.edu
Web-Page: *http://bios.uic.edu/bios/people/faculty/yury-polikanov
<http://bios.uic.edu/bios/people/faculty/yury-polikanov>*
[image: Image result for uic logo]
--



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[ccp4bb] PostDoctoral Position in Structural Biology - Structural Studies of Ribosome Functional Complexes

[Yury Polikanov]

Dear Colleagues,

We
​ ​
have an open position for a P
ost
D
oc
​ ​
in my laboratory
​
at the University of Illinois at Chicago, USA
​ ​
(https://bios.uic.edu/bios/people/faculty/yury-polikanov).
​ ​
The research in o
ur laboratory is focused on understanding basic principles of protein
synthesis in bacteria, the modes of action of ribosome-targeting
antibiotics, and mechanisms of drug resistance at a structural level. We
use macromolecular X-ray crystallography approach to determine
high-resolution structures of ribosome functional complexes.

​​
The successful candidate should hold a PhD in chemistry, biochemistry
,
biophysics
or related areas and experience in structural biology.
​ ​
​
​
The successful candidate
​ ​
should
 also
have an excellent track record and experience in X-ray crystallography as
well as
​ ​
in
protein expression
,
purification
​
,
crystallization, data collection, structure determination
,
and model refinement.
​
 Advanced computer s
kills together with
experience
​ ​
i
n complementary biochemical and biophysical techniques related to the
studies of the 70S ribosome
would be a benefit.
​ ​
Preference will be given to those who have a strong drive
,
motivation
, and passion for discovery
.

​
Applicants should submit
​ ​
cover letter,
curriculum vitae
​ ​
(CV)
,
​ ​
and contact information for
t
hree
references
​ ​
directly
to Dr.
​ ​
Y
ury Polikanov
(
yu...@uic.edu
).

W
ith best regards,
Yury

​
​
-- 
--
Yury Polikanov, Ph.D.
Assistant Professor
Department of Biological Sciences
College of Liberal Arts and Sciences
University of Illinois at Chicago
900 South Ashland Avenue, MBRB 4170
Chicago, IL 60607
Tel: 1-312-413-2408 (Office)
Tel: 1-312-355-0463 (Laboratory)
Fax: 1-312-413-2691
E-mail: yu...@uic.edu
Web-Page: *http://bios.uic.edu/bios/people/faculty/yury-polikanov
<http://bios.uic.edu/bios/people/faculty/yury-polikanov>*​​

--
​

[ccp4bb] Visiting Research Specialist Position Available at UIC

[Yury Polikanov]

TItle: Visiting Research Specialist

Department: Department of Biological Sciences, University of Illinois at
Chicago

Location: Chicago, Illinois, USA



Description: The Department of Biological Sciences, is recruiting a
Visiting Research Specialist to Conduct research by using X-ray
crystallography techniques to obtain structural basis for various functions
of the bacterial ribosome and its inhibition by different small-molecule
inhibitors. The successful candidate should have capabilities in molecular
biology, biophysics, and X-ray crystallography methods, such as various
molecular cloning techniques, protein chemistry techniques, as well as
expert level of knowledge of the following software: XDS, HKL2000, Coot,
PyMol, CCP4, Phenix, Adobe Illustrator, Adobe Premier. A track record of
training junior researchers is highly desirable. The successful candidate
would conduct his/her own research and assist with the principal
investigator’s research, while training other laboratory personnel in
various techniques, experiments and the appropriate use of research
equipment. They would also perform data analysis and manage, document, and
help with the dissemination of research activities for publication and
outreach activities.



Duties:

• Perform research relevant to the assigned projects;

• Isolate and crystallize bacterial ribosomes;

• Purify all additional components necessary for the crystallization
experiments, such as recombinant proteins, tRNAs;

• Collect X-ray diffraction data from the ribosome crystals at the APS
Synchrotron;

• Perform data analysis; coordinate, analyze, and document results for
publication;

• Directly participate in writing papers and grants based on the
experimental data;

• Train undergraduate and graduate students in research methods, use of
equipment, record keeping, and laboratory database entry;

• Attend weekly group meetings and journal clubs.



Qualifications:

• Bachelor’s degree in biological sciences required, Master’s degree or
higher is preferred

• Minimum of 3 years of laboratory research experience is required

• Strong background in biochemistry and molecular biology is required.

• Experience in X-ray crystallography is not required but highly desirable

• Experience with molecular cloning and protein chemistry is highly
desirable.

• Experience with bacterial ribosomes and bacterial translation systems.

• Successful candidate should be able to walk into the laboratory and be
able start working without significant additional training in basic
molecular biology techniques.





For fullest consideration please complete the on-line application and
upload a resume by June 6, 2018 at https://jobs.uic.edu/job-
board/job-details?jobID=95609&job=visiting-research-
specialist-biological-sciences.



The University of Illinois at Chicago is an Equal Opportunity, Affirmative
Action employer. Minorities, women, veterans and individuals with
disabilities are encouraged to apply.



The University of Illinois may conduct background checks on all job
candidates upon acceptance of a contingent offer. Background checks will be
performed in compliance with the Fair Credit Reporting Act.


-- 
------
Yury Polikanov, Ph.D.
Assistant Professor
Department of Biological Sciences
College of Liberal Arts and Sciences
University of Illinois at Chicago
900 South Ashland Avenue, MBRB 4170
Chicago, IL 60607
Tel: 1-312-413-2408 (Office)
Tel: 1-312-355-0463 (Laboratory)
Fax: 1-312-413-2691
E-mail: yu...@uic.edu
Web-Page: *http://bios.uic.edu/bios/people/faculty/yury-polikanov
<http://bios.uic.edu/bios/people/faculty/yury-polikanov>*

[image: Inline image 1]
--

[ccp4bb] Open-rank Faculty Position in Biology - School of Advanced Studies at the University of Tyumen (Russia)

[Yury Polikanov]

A new open-rank faculty position (Professor of Biology) is available at the
School of Advanced Studies at the University of Tyumen
(Siberia, Russia).

The School of Advanced Studies (SAS) https://sas.utmn.ru/en/, a new and
rapidly growing institution at the University of Tyumen, is recruiting
professors (open rank) in biology (including evolutionary biology) and
neuroscience. SAS operates in English, so no knowledge of Russian is
required and currently employs 20 professors from 7 countries.

SAS's distinctive feature is the organization of research around
multidisciplinary projects. The teams will be formed and projects outlined
at the project design session in March 2019 (see info
on the previous such session here:
https://sas.utmn.ru/en/project-design-session-2018-en/). We will hire the
most promising teams to realize their research projects at SAS while
contributing to SAS educational process.

The incoming professors may also receive a joint appointment with X-Bio:
Institute for Environmental and Ecological Biology at the University of
Tyumen https://www.utmn.ru/en/x-bio/institute/, which will be extending its
scope to become an Institute of Life Sciences in the coming years. The
direction of the development of both SAS and X-Bio’s research agenda will
to an important extent reflect research interests of their new faculty.
Both institutions are central to the University of Tyumen strategy
supported by the Russian Academic Excellence project https://5top100.ru/en/.

Successful candidates will be asked to teach at SAS liberal arts and
sciences undergraduate program as well as, in case of a joint appointment,
at X-Bio international MA programs. Successful candidates will receive
European-level salaries, health insurance, and research travel funds, as
well as access to available lab equipment. Receiving an internal grant to
purchase equipment the university does not have will also be an option.
Some information on Tyumen is
available here: https://sas.utmn.ru/en/siberia-light/.

Please send a CV, three letters of reference, and a cover letter
describing your academic itinerary and research plans in the framework of a
hypothetical multidisciplinary team project via e-mail
to s...@utmn.ru before December 15, 2018.



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[ccp4bb] PostDoctoral Position in Structural Biology at the University of Illinois at Chicago (UIC) to Study the Ribosome

[Yury Polikanov]

We have an immediate opening for a talented, highly motivated postdoctoral
scholar in my laboratory at the University of Illinois located in downtown
Chicago, IL (USA)
 t
o study the structure and function of the ribosome (
https://bios.uic.edu/bios/people/faculty/yury-polikanov).

The research in o
ur laboratory is focused on understanding basic principles of protein
synthesis in bacteria, the modes of action of ribosome-targeting
antibiotics, and mechanisms of drug resistance at a structural level. The
successful candidate will be specifically involved in determination of
high-resolution structures of ribosome functional complexes using
macromolecular X-ray crystallography techniques.

*Basic qualifications:*

   - PhD in chemistry, biochemistry
   ,
   biophysics,
   or a related field;
   - Practical skills in molecular biology, protein expression,
   purification, and various biochemical techniques;
   - Experience in structural biology (cryo-EM or X-ray crystallography);

*The successful candidate is also expected to:*


   - Drive forward the projects;
   - Act independently or semi-independently in terms of planning and
   executing the experiments;
   - Compile, analyze, and prepare data for publications;
   - Assist with training of graduate and undergraduate students.

Review of applications will begin immediately and will continue until the
position is filled. Interested applicants should send their CV along with a
cover letter briefly describing their research accomplishments, current
research interests and contact information for three references directly to
Dr. Yury Polikanov, yu...@uic.edu.

-- 
--
Yury Polikanov, Ph.D.
Assistant Professor
Department of Biological Sciences
College of Liberal Arts and Sciences
University of Illinois at Chicago
900 South Ashland Avenue, MBRB 4170
Chicago, IL 60607
Tel: 1-312-413-2408 (Office)
Tel: 1-312-355-0463 (Laboratory)
Fax: 1-312-413-2691
E-mail: yu...@uic.edu
Web-Page: *http://bios.uic.edu/bios/people/faculty/yury-polikanov
<http://bios.uic.edu/bios/people/faculty/yury-polikanov>*

[image: Inline image 1]
--



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[ccp4bb] NIH/NSF-Funded Research Specialist Position in Structural Biology at the University of Illinois at Chicago

[Yury Polikanov]

NIH/NSF-Funded Research Specialist Position in Structural Biology at the
University of Illinois at Chicago



The Polikanov Laboratory at the University of Illinois at Chicago (IL, USA)
is looking for talented, skillful, and highly motivated researchers to fill
the NIH/NSF-funded Visiting Research Specialist positions to study the
structure and function of the bacterial ribosome.



The research in the Polikanov Laboratory is focused on understanding the
basic principles of protein synthesis in bacteria, the modes of action of
ribosome-targeting antibiotics, and the mechanisms of drug resistance at a
structural level. More information about Dr. Polikanov research can be
obtained from the most recent publications (
https://www.ncbi.nlm.nih.gov/sites/myncbi/yury.polikanov.1/bibliography/50395623/public/?sort=date&direction=descending)
or found on the laboratory web-page (
https://bios.uic.edu/bios/people/faculty/yury-polikanov). The successful
candidate will be involved in determination of high-resolution structures
of ribosome functional complexes with various protein translation factors,
tRNAs, and antibiotics using macromolecular X-ray crystallography
techniques.



Basic qualifications:

• BS degree in chemistry, biochemistry, biophysics, or a related field is
required;

• MS degree or higher is preferred;• Minimum of 3 years of laboratory
research experience is required;

• Strong background in biochemistry and molecular biology is required;

• Practical skills with the most standard methods currently used in
molecular biology, and biochemistry (such as protein expression,
purification);

• Experience in structural biology (cryo-EM or X-ray crystallography) is
not required but is highly desirable;

• Experience in RNA biology field is not required but is highly desirable;



The successful candidate is also expected to:

• Act independently in terms of planning and executing the experiments;

• Compile, analyze, and prepare data for publications;

• Assist with training of graduate and undergraduate students.



Interested candidates should submit their CV, cover letter, and contact
information for three references at
https://jobs.uic.edu/job-board/job-details?jobID=113640&job=visiting-research-specialist-biological-sciences
by June 28, 2019. Cover letter should be describing how previous research
accomplishments and scientific interests of a candidate fit with the scope
of the research in the Polikanov Lab.



The University of Illinois at Chicago is an Equal Opportunity, Affirmative
Action employer. Minorities, women, veterans and individuals with
disabilities are encouraged to apply.

The University of Illinois may conduct background checks on all job
candidates upon acceptance of a contingent offer. Background checks will be
performed in compliance with the Fair Credit Reporting Act



*Jacquelyn DeLaurentis*

*Human Resource Associate*



*Department of Biological Sciences*

*The University of Illinois at Chicago*



*845 W Taylor St. *

*3238 SES, MC 066*

*Chicago, IL 60607*

*(312) 996-2213*

*jdel...@uic.edu *

[image: UIC Logo]



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[ccp4bb] NIH/NSF-Funded Visiting Research Specialist Position at the University of Illinois at Chicago

[Yury Polikanov]

NIH/NSF-Funded Visiting Research Specialist Position in Structural Biology
at the University of Illinois at Chicago



The Polikanov Laboratory at the University of Illinois at Chicago (IL, USA)
is looking for talented, skillful, and highly motivated researchers to fill
the NIH/NSF-funded Visiting Research Specialist position to study the
structure and function of the bacterial ribosome.



The research in the Polikanov Laboratory is focused on understanding the
basic principles of protein synthesis in bacteria, the modes of action of
ribosome-targeting antibiotics, and the mechanisms of drug resistance at a
structural level. More information about Dr. Polikanov research can be
obtained from the most recent publications (
https://www.ncbi.nlm.nih.gov/sites/myncbi/yury
.polikanov.1/bibliography/50395623/public/?sort=date&direction=descending
<https://nam03.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fmyncbi%2Fyury.polikanov.1%2Fbibliography%2F50395623%2Fpublic%2F%3Fsort%3Ddate%26direction%3Ddescending&data=02%7C01%7Cmagagnon%40UTMB.EDU%7C335fff80dacd4c0bd99f08d6ce524c4a%7C7bef256d85db4526a72d31aea2546852%7C0%7C0%7C636923250195853604&sdata=uDmihqAopo0C4LQGCQSc%2BkWtEt%2BAyzU1Fa4uGjQXdug%3D&reserved=0>)
or found on the laboratory web-page (
https://bios.uic.edu/bios/people/faculty/yury-polikanov
<https://nam03.safelinks.protection.outlook.com/?url=https%3A%2F%2Fbios.uic.edu%2Fbios%2Fpeople%2Ffaculty%2Fyury-polikanov&data=02%7C01%7Cmagagnon%40UTMB.EDU%7C335fff80dacd4c0bd99f08d6ce524c4a%7C7bef256d85db4526a72d31aea2546852%7C0%7C0%7C636923250195863616&sdata=wqkXbN8LlOLxRi%2F47A0%2BG23XdJ1q5ToXYWC%2BwQz2wi4%3D&reserved=0>).
The successful candidate will be involved in determination of
high-resolution structures of ribosome functional complexes with various
protein translation factors, tRNAs, and antibiotics using macromolecular
X-ray crystallography techniques.



Basic qualifications:

• BS degree in chemistry, biochemistry, biophysics, or a related field is
required;

• MS degree or higher is preferred;• Minimum of 3 years of laboratory
research experience is required;

• Strong background in biochemistry and molecular biology is required;

• Practical skills with the most standard methods currently used in
molecular biology, and biochemistry (such as protein expression,
purification);

• Experience in structural biology (cryo-EM or X-ray crystallography) is
not required but is highly desirable;

• Experience in RNA biology field is not required but is highly desirable;



The successful candidate is also expected to:

• Act independently in terms of planning and executing the experiments;

• Compile, analyze, and prepare data for publications;

• Assist with training of graduate and undergraduate students.



Interested candidates should submit their CV, cover letter, and contact
information for three references at
https://jobs.uic.edu/job-board/job-details?jobID=115527
<http://email.hiretouch.com/wf/click?upn=JvIYOHR1NyNpkeKMwd5M2xA-2FeX5NPtxOrRNWIAKnW-2F3-2BCAhNPlV-2FOdnQaNeH8GNVhEWHl-2FZ9rpFfezjleySkog-3D-3D_YAPPOS5P7zCatyggPQVXDeqJl31RWk-2BwfuPSeGQBwtnEUdwem1YwXIvXLTrn9-2Fn04mLYNlr99BFmw83AewKXgWkrDK5rJyUivNX7tEdw-2BxcHj7tY3OPG-2F5szP7GHWYlK8imNHcw1Yqe1-2F5A-2FPsT1aHDvsEmrnUDp57V2J3z8qKFLFMwgqSOtw7yB05A34F8E08bJE-2Bg9fM4WRB6k8KXat6aofUiupvFuCmjORKzXusELC5YkqtdNzcrGioHAUDfzLnjdxdmGe0K00EOTxNHGIRfDdngqHwarhkWNeJND5nqVwwqqI3kkAaSU16K22VkVsMG-2F-2B39fgOvNn2dN91STkA-3D-3D>
 by July 1, 2019. Cover letter should be describing how previous research
accomplishments and scientific interests of a candidate fit with the scope
of the research in the Polikanov Lab.



The University of Illinois at Chicago is an Equal Opportunity, Affirmative
Action employer. Minorities, women, veterans and individuals with
disabilities are encouraged to apply.


The University of Illinois may conduct background checks on all job
candidates upon acceptance of a contingent offer. Background checks will be
performed in compliance with the Fair Credit Reporting Act


*Jacquelyn DeLaurentis*

*Human Resource Associate*


*Department of Biological Sciences*
*The University of Illinois at Chicago*

*845 W Taylor St. *
*3238 SES, MC 066*

*Chicago, IL 60607*

*(312) 996-2213*


*jdel...@uic.edu *


[image: UIC Logo]



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[ccp4bb] Research Specialist Position at the University of Illinois to Study Ribosome Structure | POLIKANOV Lab

[Yury Polikanov]

*Research Specialist Position Available, Department of Biological Sciences,
University of Illinois at Chicago - Polikanov Lab*

*The Polikanov Laboratory in the Department of Biological Sciences at the
University of Illinois at Chicago (IL, USA) is looking for a talented,
skillful, and highly motivated researcher to fill the Research Specialist
position to study the structure and function of the bacterial ribosome.*

For fullest consideration, please submit an application and cover letter
describing your scientific interests and how your previous research
accomplishments and scientific interests fit with the scope of the research
in the Polikanov research group at
https://uic.csod.com/ux/ats/careersite/1/home/requisition/7573?c=uic

*Position Summary:*
The research in the Polikanov Laboratory at UIC is focused on understanding
the basic principles of protein synthesis in bacteria, the modes of action
of ribosome-targeting antibiotics, and the mechanisms of drug resistance at
a structural level. This position is involved in the determination of
high-resolution structures of ribosome functional complexes with various
protein translation factors, tRNAs, and antibiotics using macromolecular
X-ray crystallography and potentially cryo-EM techniques. Expected
contributes to the design and delivery of research projects and
collaborates with researchers to develop, execute, and interpret research
projects. Performs complex laboratory and data collection techniques.

*Duties & Responsibilities:*

   - Perform research relevant to the assigned projects;
   - Isolate, purify, and crystallize bacterial ribosomes;
   - Purify all additional components necessary for the crystallization
   experiments, such as recombinant proteins, tRNAs;
   - Collect X-ray diffraction data from the ribosome crystals at the APS
   and NSLS-II Synchrotrons;
   - Perform structural data analysis;
   - Coordinate, analyze, and document results for publication;
   - Directly participate in writing papers and grants based on the
   experimental data;
   - Train undergraduate and graduate students in research methods, use of
   equipment, record keeping, and laboratory database entry;
   - Attend weekly group meetings and journal club seminars.
   - Perform other related duties and participate in special projects as
   assigned.

*Minimum Qualifications:*

   - A bachelor’s degree in chemistry, biochemistry, biophysics, or a
   related field is required.
   - A master’s degree in chemistry, biochemistry, biophysics, or a related
   field is preferred.
   - A minimum of 3 years related research experience.
   - Possesses and applies comprehensive knowledge of research principles,
   concepts, practices, and methods.
   - Proficient in standard molecular biology and biochemistry lab
   techniques, such as protein expression, and purification

*Preferred Qualifications:*

   - Experience in structural biology (cryo-EM or X-ray crystallography);
   - Experience in RNA biology, ribosome, and/or protein synthesis fields.

*About the University of Illinois Chicago:*
UIC is among the nation’s preeminent urban public research universities, a
Carnegie RU/VH research institution, and the largest university in Chicago.
UIC serves over 34,000 students, comprising one of the most diverse student
bodies in the nation and is designated as a Minority Serving Institution
(MSI), an Asian American and Native American Pacific Islander Serving
Institution (AANAPSI) and a Hispanic Serving Institution (HSI). Through its
16 colleges, UIC produces nationally and internationally recognized
multidisciplinary academic programs in concert with civic, corporate and
community partners worldwide, including a full complement of health
sciences colleges. By emphasizing cutting-edge and transformational
research along with a commitment to the success of all students, UIC
embodies the dynamic, vibrant and engaged urban university. Recent “Best
Colleges” rankings published by U.S. News & World Report, found UIC climbed
up in its rankings among top public schools in the nation and among all
national universities. UIC has nearly 260,000 alumni, and is one of the
largest employers in the city of Chicago.

*The University of Illinois System is an equal opportunity employer,
including but not limited to disability and/or veteran status, and complies
with all applicable state and federal employment mandates. Please
visit Required Employment Notices and Posters
 to
view our non-discrimination statement and find additional information about
required background checks, sexual harassment/misconduct disclosures,
COVID-19 vaccination requirement, and employment eligibility review through
E-Verify. **The university provides accommodations to applicants and
employees. Request an Accommodation
*



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