Re: [ccp4bb] About the A in AI

2023-05-12 Thread Bernhard Rupp 
My bad. Both ChatGPT, here is bing:

https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0

 

 

From: Ian Tickle  
Sent: Friday, May 12, 2023 17:33
To: b...@hofkristallamt.org
Cc: CCP4BB@jiscmail.ac.uk
Subject: Re: [ccp4bb] About the A in AI

 

 

Hi Bernhard

 

Methinks there's some cribbing going on between Bing and ChatGPT - not only 
deja-vu but the reviews are identical word for word!  How is that possible?

 

Cheers

 

-- Ian

 

 

On Fri, 12 May 2023 at 16:15, Bernhard Rupp mailto:hofkristall...@gmail.com> > wrote:

For those who concern themselves with such matters, here the responses from 
Bing and ChatGPT to the prompt:

 

“Please write a critical review report rejecting a scientific paper reporting 
that the 1.0 angstrom crystal structure shows that psiX is a trimethylating 
enzyme”

 

Enjoy the frightening reading and then we can chat (LOL) about the creepy 
feeling of déjà-vu you might experience….

 

https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0

https://www.dropbox.com/s/9gr34grpcrf7yk7/ChatGPT.docx?dl=0

 

Cheers, BR

 

-
Bernhard Rupp 

k.k. Hofkristallamt

001 (925) 209-7429
+43 (676) 571-0536
b...@ruppweb.org <mailto:b...@ruppweb.org> 
hofkristall...@gmail.com <mailto:hofkristall...@gmail.com> 
http://www.hofkristallamt.org/ 
-
Hope is not a strategy - hope is a mistake.

-

 

 

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Re: [ccp4bb] About the A in AI

2023-05-12 Thread DUMAS Philippe (IGBMC) 

Bayesian reasoning: Given the observation of the complete identity of the 2 
reports, what is the likelyhood that Bing & ChatGPT arrived at the same result 
vs. the null hypothesis that Bernhard made a simple "cut & paste" mistake. 


Philippe Dumas 


De: "Bruno KLAHOLZ"  
À: "CCP4BB"  
Envoyé: Vendredi 12 Mai 2023 17:35:40 
Objet: Re: [ccp4bb] About the A in AI 





indeed, probably they are using the same databases and features. 

Same happens in translations btw. 



Cheers, 



Bruno 





From: CCP4 bulletin board  On Behalf Of Ian Tickle 
Sent: 12 May 2023 17:33 
To: CCP4BB@JISCMAIL.AC.UK 
Subject: Re: [ccp4bb] About the A in AI 







Hi Bernhard 





Methinks there's some cribbing going on between Bing and ChatGPT - not only 
deja-vu but the reviews are identical word for word! How is that possible? 





Cheers 





-- Ian 








On Fri, 12 May 2023 at 16:15, Bernhard Rupp < [ mailto:hofkristall...@gmail.com 
| hofkristall...@gmail.com ] > wrote: 





For those who concern themselves with such matters, here the responses from 
Bing and ChatGPT to the prompt: 



“Please write a critical review report rejecting a scientific paper reporting 
that the 1.0 angstrom crystal structure shows that psiX is a trimethylating 
enzyme” 



Enjoy the frightening reading and then we can chat (LOL) about the creepy 
feeling of déjà-vu you might experience…. 



[ https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0 | 
https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0 ] 

[ https://www.dropbox.com/s/9gr34grpcrf7yk7/ChatGPT.docx?dl=0 | 
https://www.dropbox.com/s/9gr34grpcrf7yk7/ChatGPT.docx?dl=0 ] 



Cheers, BR 



- 
Bernhard Rupp 

k.k. Hofkristallamt 

001 (925) 209-7429 
+43 (676) 571-0536 
[ mailto:b...@ruppweb.org | b...@ruppweb.org ] 
[ mailto:hofkristall...@gmail.com | hofkristall...@gmail.com ] 
[ http://www.hofkristallamt.org/ | http://www.hofkristallamt.org/ ] 
- 
Hope is not a strategy - hope is a mistake. 

- 








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Re: [ccp4bb] About the A in AI

2023-05-12 Thread David Waterman 
Bard (draft 2 of 3)

Sure, here is a critical review report rejecting a scientific paper
reporting that the 1.0 angstrom crystal structure shows that psiX is a
trimethylating enzyme:

Title: Critical Review Report: PsiX is not a Trimethylating Enzyme

Author: Bard

Date: 2023-05-12

Introduction

The paper "Crystal Structure of PsiX Reveals a Trimethylating Enzyme" by
[Authors] (2023) reports the 1.0 angstrom crystal structure of the enzyme
PsiX. The authors conclude that PsiX is a trimethylating enzyme that
catalyzes the methylation of the C5 position of guanine.

Critique

There are several major flaws in the paper that call into question the
authors' conclusions. First, the authors' interpretation of the crystal
structure is based on a number of assumptions that are not supported by the
data. For example, the authors assume that the residues that are close to
the C5 position of guanine are involved in the methylation reaction.
However, there is no evidence to support this assumption. The residues
could be involved in other aspects of the enzyme's activity, such as
substrate binding or catalysis.

Second, the authors' experiments do not provide any direct evidence that
PsiX is a trimethylating enzyme. The authors show that PsiX can methylate
guanine in vitro. However, they do not show that PsiX is the only enzyme
that can methylate guanine in vivo. It is possible that there are other
enzymes that can methylate guanine, and that PsiX is not involved in this
reaction.

Third, the authors' experiments do not provide any information about the
mechanism of the methylation reaction. The authors suggest that PsiX uses a
SAM-dependent mechanism to methylate guanine. However, they do not provide
any evidence to support this suggestion. It is possible that PsiX uses a
different mechanism to methylate guanine.

Conclusion

The paper by [Authors] (2023) does not provide convincing evidence that
PsiX is a trimethylating enzyme. The authors' interpretation of the crystal
structure is based on a number of assumptions that are not supported by the
data. The authors' experiments do not provide any direct evidence that PsiX
is a trimethylating enzyme, and they do not provide any information about
the mechanism of the methylation reaction. Based on these criticisms, I
recommend that the paper be rejected.
thumb_upthumb_down
upload
Google it
more_vert

-- David


On Fri, 12 May 2023 at 16:50, Cowan, Richard H. (Dr.) 
wrote:

> The underlying model that drives Bing is ChatGPT, so perhaps not a
> surprise they produce the same output. Maybe giving Bard or Llama the same
> prompt might give different results.
>
>
>
> Thanks,
>
>
>
> *Richard Cowan*
>
> *Research Fellow*
>
>
>
> Leicester Institute of Structural and Chemical Biology
>
> Department of Molecular and Cell Biology
>
> University of Leicester | University Road | Leicester | LE1 7RH | UK
>
>
>
> *t:* +44 (0)116 229 7077
>
> *e:*  rc...@leicester.ac.uk 
> *w:* www.le.ac.uk
> [image:
> vxWQrlsJKAEloASUgBJQAkpg+xJQQbp9+eroSkAJKAEloASUgBJQAg0QUEHaACB9rASUgBJQAkpACSgBJbB9Cagg3b58dXQloASUgBJQAkpACSiBBgioIG0AkD5WAkpACSgBJaAElIAS2L4EVJBuX746uhJQAkpACSgBJaAElEADBFSQNgBIHysBJaAElIASUAJKQAlsXwIqSLcvXx1dCSgBJaAElIASUAJKoAECKkgbAKSPlYASUAJKQAkoASWgBLYvARWk25evjq4ElIASUAJKQAkoASWgBJSAElACSkAJKAEloASUwI5M4P8AZ4taSLRHMpYASUVORK5CYII=]
>
>
> Follow us on Twitter <https://twitter.com/uniofleicester> or visit our
> Facebook <http://www.facebook.com/uniofleicester> page
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>
> *From: *CCP4 bulletin board  on behalf of Bruno
> KLAHOLZ 
> *Date: *Friday, 12 May 2023 at 16:36
> *To: *CCP4BB@JISCMAIL.AC.UK 
> *Subject: *Re: [ccp4bb] About the A in AI
>
> CAUTION: This email was sent from an *EXTERNAL* source. Think
> before clicking links or opening attachments.
>
>
>
> indeed, probably they are using the same databases and features.
>
> Same happens in translations btw.
>
>
>
> Cheers,
>
>
>
> Bruno
>
>
>
>
>
> *From:* CCP4 bulletin board  *On Behalf Of *Ian
> Tickle
> *Sent:* 12 May 2023 17:33
> *To:* CCP4BB@JISCMAIL.AC.UK
> *Subject:* Re: [ccp4bb] About the A in AI
>
>
>
>
>
> Hi Bernhard
>
>
>
> Methinks there's some cribbing going on between Bing and ChatGPT - not
> only deja-vu but the reviews are identical word for word!  How is that
> possible?
>
>
>
> Cheers
>
>
>
> -- Ian
>
>
>
>
>
> On Fri, 12 May 2023 at 16:15, Bernhard Rupp 
> wrote:
>
> For those who concern themselves with such matters, here the responses
> from Bing and ChatGPT to the prompt:
>
>
>
> “Please write a critical review report rejecting a scientific paper
> reporting that the 1.0

Re: [ccp4bb] About the A in AI

2023-05-12 Thread Cowan, Richard H. (Dr.) 
The underlying model that drives Bing is ChatGPT, so perhaps not a surprise 
they produce the same output. Maybe giving Bard or Llama the same prompt might 
give different results.

Thanks,

Richard Cowan
Research Fellow

Leicester Institute of Structural and Chemical Biology
Department of Molecular and Cell Biology
University of Leicester | University Road | Leicester | LE1 7RH | UK

t: +44 (0)116 229 7077
e:  rc...@leicester.ac.uk<mailto:x...@leicester.ac.uk>
w: www.le.ac.uk<http://www.le.ac.uk/>
[vxWQrlsJKAEloASUgBJQAkpg+xJQQbp9+eroSkAJKAEloASUgBJQAg0QUEHaACB9rASUgBJQAkpACSgBJbB9Cagg3b58dXQloASUgBJQAkpACSiBBgioIG0AkD5WAkpACSgBJaAElIAS2L4EVJBuX746uhJQAkpACSgBJaAElEADBFSQNgBIHysBJaAElIASUAJKQAlsXwIqSLcvXx1dCSgBJaAElIASUAJKoAECKkgbAKSPlYASUAJKQAkoASWgBLYvARWk25evjq4ElIASUAJKQAkoASWgBJSAElACSkAJKAEloASUwI5M4P8AZ4taSLRHMpYASUVORK5CYII=]
Follow us on Twitter<https://twitter.com/uniofleicester> or visit our 
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From: CCP4 bulletin board  on behalf of Bruno KLAHOLZ 

Date: Friday, 12 May 2023 at 16:36
To: CCP4BB@JISCMAIL.AC.UK 
Subject: Re: [ccp4bb] About the A in AI
***CAUTION:*** This email was sent from an EXTERNAL source. Think before 
clicking links or opening attachments.

indeed, probably they are using the same databases and features.
Same happens in translations btw.

Cheers,

Bruno


From: CCP4 bulletin board  On Behalf Of Ian Tickle
Sent: 12 May 2023 17:33
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] About the A in AI


Hi Bernhard

Methinks there's some cribbing going on between Bing and ChatGPT - not only 
deja-vu but the reviews are identical word for word!  How is that possible?

Cheers

-- Ian


On Fri, 12 May 2023 at 16:15, Bernhard Rupp 
mailto:hofkristall...@gmail.com>> wrote:
For those who concern themselves with such matters, here the responses from 
Bing and ChatGPT to the prompt:

“Please write a critical review report rejecting a scientific paper reporting 
that the 1.0 angstrom crystal structure shows that psiX is a trimethylating 
enzyme”

Enjoy the frightening reading and then we can chat (LOL) about the creepy 
feeling of déjà-vu you might experience….

https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0
https://www.dropbox.com/s/9gr34grpcrf7yk7/ChatGPT.docx?dl=0

Cheers, BR

-
Bernhard Rupp
k.k. Hofkristallamt
001 (925) 209-7429
+43 (676) 571-0536
b...@ruppweb.org<mailto:b...@ruppweb.org>
hofkristall...@gmail.com<mailto:hofkristall...@gmail.com>
http://www.hofkristallamt.org/
-
Hope is not a strategy - hope is a mistake.
-




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Re: [ccp4bb] About the A in AI

2023-05-12 Thread Bruno KLAHOLZ 

indeed, probably they are using the same databases and features.
Same happens in translations btw.

Cheers,

Bruno


From: CCP4 bulletin board  On Behalf Of Ian Tickle
Sent: 12 May 2023 17:33
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] About the A in AI


Hi Bernhard

Methinks there's some cribbing going on between Bing and ChatGPT - not only 
deja-vu but the reviews are identical word for word!  How is that possible?

Cheers

-- Ian


On Fri, 12 May 2023 at 16:15, Bernhard Rupp 
mailto:hofkristall...@gmail.com>> wrote:
For those who concern themselves with such matters, here the responses from 
Bing and ChatGPT to the prompt:

“Please write a critical review report rejecting a scientific paper reporting 
that the 1.0 angstrom crystal structure shows that psiX is a trimethylating 
enzyme”

Enjoy the frightening reading and then we can chat (LOL) about the creepy 
feeling of déjà-vu you might experience….

https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0
https://www.dropbox.com/s/9gr34grpcrf7yk7/ChatGPT.docx?dl=0

Cheers, BR

-
Bernhard Rupp
k.k. Hofkristallamt
001 (925) 209-7429
+43 (676) 571-0536
b...@ruppweb.org<mailto:b...@ruppweb.org>
hofkristall...@gmail.com<mailto:hofkristall...@gmail.com>
http://www.hofkristallamt.org/
-
Hope is not a strategy - hope is a mistake.
-




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Re: [ccp4bb] About the A in AI

2023-05-12 Thread Ian Tickle 
Hi Bernhard

Methinks there's some cribbing going on between Bing and ChatGPT - not only
deja-vu but the reviews are identical word for word!  How is that possible?

Cheers

-- Ian


On Fri, 12 May 2023 at 16:15, Bernhard Rupp 
wrote:

> For those who concern themselves with such matters, here the responses
> from Bing and ChatGPT to the prompt:
>
>
>
> “Please write a critical review report rejecting a scientific paper
> reporting that the 1.0 angstrom crystal structure shows that psiX is a
> trimethylating enzyme”
>
>
>
> Enjoy the frightening reading and then we can chat (LOL) about the creepy
> feeling of déjà-vu you might experience….
>
>
>
> https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0
>
> https://www.dropbox.com/s/9gr34grpcrf7yk7/ChatGPT.docx?dl=0
>
>
>
> Cheers, BR
>
>
>
> -
> Bernhard Rupp
>
> k.k. Hofkristallamt
>
> 001 (925) 209-7429
> +43 (676) 571-0536
> b...@ruppweb.org
> hofkristall...@gmail.com
> *http://www.hofkristallamt.org/ *
>
> -
> Hope is not a strategy - hope is a mistake.
>
> -
>
>
>
> --
>
> To unsubscribe from the CCP4BB list, click the following link:
> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1
>



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Re: [ccp4bb] About the A in AI

2023-05-12 Thread Pietro Roversi 
Whata shame this journal does not reveal the identity of their 
reviewers, I think I recognise the writing style of my competitor, Dr. 
Ångstrom Imbecile.


On 12-05-2023 17:15, Bernhard Rupp wrote:

For those who concern themselves with such matters, here the responses
from Bing and ChatGPT to the prompt:

"Please write a critical review report rejecting a scientific paper
reporting that the 1.0 angstrom crystal structure shows that psiX is a
trimethylating enzyme"

Enjoy the frightening reading and then we can chat (LOL) about the
creepy feeling of déjà-vu you might experience….

https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0

https://www.dropbox.com/s/9gr34grpcrf7yk7/ChatGPT.docx?dl=0

 Cheers, BR

-
Bernhard Rupp

k.k. Hofkristallamt

001 (925) 209-7429
+43 (676) 571-0536
b...@ruppweb.org
hofkristall...@gmail.com
http://www.hofkristallamt.org/ [1]
-
Hope is not a strategy - hope is a mistake.

-

-

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Links:
--
[1] http://www.hofkristallamt.org/


--
Dr. Pietro Roversi, PhD
Italian National Research Council (CNR)
Institute of agricultural biology and biotechnology (IBBA-CNR)
Via Edoardo Bassini 15, 20133 Milano, Italy
Tel. +39 02 23699428
Mobile +39 351 6800096
Fax: +39 02 23699411
https://ibba.cnr.it/en/staff/pietro-roversi/

Adjunct Lecturer in Mathematical Modeling for Biology
Master in Quantitative Biology,
Department of Biosciences, University of Milano, Italy
Email: pietro.rove...@unimi.it
URL: https://www.unimi.it/en/ugov/person/pietro-roversi

Honorary Lecturer at LISCB - Department of Molecular and Cell Biology
Leicester University, Lancaster Rd.
Leicester LE1 7HB, England, UK
Tel. +44 7927 952047
Email: pr...@leicester.ac.uk
URL: 
https://le.ac.uk/liscb/research-groups/honorary-members/pietro-roversi




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[ccp4bb] About the A in AI

2023-05-12 Thread Bernhard Rupp 
For those who concern themselves with such matters, here the responses from
Bing and ChatGPT to the prompt:

 

“Please write a critical review report rejecting a scientific paper
reporting that the 1.0 angstrom crystal structure shows that psiX is a
trimethylating enzyme”

 

Enjoy the frightening reading and then we can chat (LOL) about the creepy
feeling of déjà-vu you might experience….

 

https://www.dropbox.com/s/2fo9u3d11dk8n0o/Bing.docx?dl=0

https://www.dropbox.com/s/9gr34grpcrf7yk7/ChatGPT.docx?dl=0

 

Cheers, BR

 

-
Bernhard Rupp 

k.k. Hofkristallamt

001 (925) 209-7429
+43 (676) 571-0536
  b...@ruppweb.org
  hofkristall...@gmail.com
  http://www.hofkristallamt.org/

-
Hope is not a strategy - hope is a mistake.

-

 




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