You and your team are invited to join Diana Monteiro <https://hwi.buffalo.edu/scientist-directory/diana-monteiro/> Hauptman-Woodward Medical Research NSF BioXFEL Science and Technology Center
March 22, 13:30 EST Beyond cryo-crystallography: new technologies for serial and time-resolved experiments https://bnl.zoomgov.com/meeting/register/vJItc-qgqTkrEvDDy1Koep3o6jrqajWyhRY Abstract The advent of cryocrystallography made determining the high resolution of proteins using X-ray diffraction truly possible by reducing radiation damage of the samples. It is still the most widely used method, accounting for the vast majority of structures currently in the Protein Data Bank. But, with the advent of brighter X-ray sources (third and fourth generation synchrotrons and X-ray free electron lasers), the number of room temperature (RT), protein structures determined by X-ray diffraction is increasing once more. The development of technologies towards serial crystallography, including sample preparation, delivery, hardware and software advances, make these studies possible. RT structures show variations in conformations, highlighting structure-function relationships important for basic science and drug discovery. In this talk I will give an overview of some of the technologies and techniques we have worked on in recent years, including their application towards time-resolved experiments. ================================================================== Vivian Stojanoff, PhD Education, Training, Outreach User Program p 1(631) 344 8375 e nsls.lifescien...@gmail.com w https://www.bnl.gov/ps/lifesciences/<https://www.bnl.gov/ps/lsbr/> Address: Center for Biomolecular Structure National Synchrotron Light Source II Building 745 Brookhaven National Laboratory Upton NY 11973 Supporting Grants: CBMS is supported by NIH-NIGMS #P30GM133893, and by the DOE-BER #KP1605010. Any work performed at NSLS-II is supported by DOE-BES under contract # DE-SC0012704. ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
