[ccp4bb] Gordon Conference on Diffraction Methods in Structural Biology
Dear all, The biannual Gordon Research Conference in Structural Biology, accompanied by the first Gordon Research Seminar, will take place in the last week of July at Bates College, New England, a few hours drive from the IUCr meeting that follows in the first week of August. The theme for the GRC is Faster, Smaller, Better: Novel Technologies for Diffraction Experiments in Molecular Biology and Drug Discovery and of the GRS (which precedes the GRC and is targeting young scientists giving them an opportunity to present their own work to their peers prior to the meeting) Towards Integrative Structural Biology. We have a truly fantastic line of speakers and discussion leaders, including John Kuriyan , Randy Read, Ana Gonzales, Ilme Schlichting , Henry Chapman , John Spence, Graeme Winter , Aina Cohen, Thomas Schneider , Gwyndaf Evans , Bob Fischetti , Flora Meilleur, Janet Newman , John Hunt , Michael Duszenko , Jose Antonio Marquez, Paul Adams , Clemens Vonrhein , Airlie McCoy , Brent Nannenga, Zbyszek Dauter , Tom Terwilliger , Garib Murshudov , Gerard Kleywegt , Paul Emsley, Dmitri Svergun , Peter Zwart , Michael Hammel , Lois Pollack, Elspeth Garman, Lisa Keefe , Gary Gililland , Aydnan Achour and Giovanna Scapin. For more details visit our web site: https://www.grc.org/programs.aspx?year=2014program=diffrac And here is the largely unavoidable motivational speech for anyone interested to my highly biased personal view: I first went to this meeting in 1998, as a young post-doc, presenting results that later led to the 'ARP/wARP' software: in fact, I had changed my slides (for the younger audience: slides were pieces of photographic film that were typically projected as mirror images of what you really wanted) a month or so before the meeting, as we got our very first models auto-built. I thought it was the most educational and exciting meeting I have ever been to, and in many ways it has shaped my research plan and my career (and my hate for golf). I wish I could also say that I never missed any of the subsequent meetings, but courtesy of the US Visa authorities and the Greek Army, I actually did a miss a couple. However, I still find them as exciting as so many years ago, but for a whole different set of scientific reasons: the diffraction methods landscape is changing rapidly, new machines and concepts make possible experiments that we do not even know what they are going to be! I am honored to be chairing this year's edition, and I hope that I will hear from at least one of you, what I had heard from a few before: this is the best meeting I have been in my life. Science aside, I am glad there is no golf course nearby the Bates College site where we are holding this meeting for the last decade, I am equally happy for the Great Outdoors site where we do the mid-week excursion, and I am looking forwards to the football (sorry: soccer) and basketball games. The Bates College boasts an excellent auditorium for the talks, a truly outstanding lounge for the poster sessions (that are always accompanied by drinks, an observation that might partially explain the tendency to finish well after midnight in a very positive spirit) and a somewhat confusingly and an unexpectedly good quality restaurant in the very friendly College site. A limited amount of (partial) bursaries to young scientists will be available for this year - when this becomes definitive we will post the news. I should also mention that one session will host eight seminars that will be selected from the poster sessions, giving all particpants the opportunity to present their own research! In the meantime, I am looking forward to welcome you all at the meeting and I hope you will register ... today! Best regards, Tassos Anastassis (Tassos, Perrakis, Principal Investigator , Staff Member Department of Biochemistry (B8, Netherlands Cancer Institute, Dept. B8, 1066 CX Amsterdam, The Netherlands Tel: +31 20 512 1951 Fax: +31 20 512 1954 Mobile , SMS: +31 6 28 597791
[ccp4bb] Gordon Conference on Diffraction Methods in Structural Biology
Dear All, Just to remind you that the closing date for registration is now just under 3 weeks away (22nd June). Best wishes Elspeth Garman (Chair) and Andrew Leslie (Vice Chair) Gordon Research Conference on Diffraction Methods in Structural Biology July 13-18, 2008, Bates College, Lewiston, Maine, USA The 2008 Gordon Research Conference on Diffraction Methods in Structural Biology will encompass advances in the methodology for macromolecular X-ray crystallography, and other diffraction/scattering applications. The full confirmed programme and timetable for the meeting can now be found below and at: http://www.grc.org/programs.aspx?year=2008program=diffrac as well as details on how to register (registration closes on 22nd June 2008 but attendance is limited to 125 researchers). All macromolecular crystallographers interested in Methods development are encouraged to apply. To promote a lively meeting, we hope that all participants will present a poster and contribute to the discussions. *Confirmed Program as at 8th May 2008.* *MACROMOLECULAR STRUCTURES: PUSHING THE BOUNDARIES * Discussion Leader: *Janet Smith* (University of Michigan at Ann Arbor, USA) *Jens Preben Morth* (Aarhus University, Denmark) Structure determination of the sodium-potassium pump *Jack Johnson* (Scripps Research Institute, USA) Crystallography of Viral Maturation Intermediates: Large Unit Cells, Particle Dynamics, and Energy Landscapes *EXPERIMENTAL ASPECTS* Discussion Leader: *James Holton* (University of California, Berkeley, USA) *Douglas Juers* (Whitman College, USA) Rational approaches to cryo-crystallography protocols *Zbyszek Dauter* (Frederick Cancer Institute, USA) A thoughtful approach to data collection *Eddie Snell* (Hauptman-Woodward Medical Research Institute, USA) Are X-rays damaging to structural biology? A case study with xylose isomerase *Martin Weik* (Institut de Biologie Structurale, Grenoble, France) Temperature-controlled cryo-crystallography to study the structural dynamics of proteins *COMPLEMENTARY TECHNIQUES* Discussion Leader: *Peter Kuhn* (Scripps Research Institute, USA) *Junko Yano* (Lawrence Berkeley National Laboratory, USA) Combination of XAS and XRD for studying a high-resolution structure of the photosynthetic water-splitting catalyst *Dean Myles* (Oak Ridge National Laboratory USA) New opportunities for neutron structural biology *Carrie Wilmot* (University of Minnesota, USA) Single crystal spectroscopy coupled to crystallography *FUTURE DIRECTIONS IN SYNCHROTRON BASED MACROMOLECULAR CRYSTALLOGRAPHY * Discussion Leader: *Elizabeth Duke* (Diamond Light Source, UK) *Soichi Wakatsuki* (KEK, Japan) Microfocus and low energy PX developments looking towards next generation synchrotron sources *Ed Mitchell* (ESRF, Grenoble, France) Bigger, better, faster, more: The ESRF Upgrade Programme *Aina Cohen* (SSRL, USA) Automation, Robotics and Remote Access at the SSRL Protein Crystallography Beam Lines *Frank von Delft* (Structural Genomics Consortium, Oxford, UK) A User's Wish: An Experiment-Focussed Beamline Interface *EMERGING TECHNOLOGIES* Discussion Leader: *Andrew Leslie* (MRC-LMB, Cambridge, UK) *Robert F. Fischetti* (GM/CA-CAT, Argonne National Laboratory, USA) Where have all the photoelectrons gone? *Clemens Schulze-Briese* (Swiss Light Source, Villigen, Switzerland) PILATUS 6M - the first year of regular user operation *COMPUTATIONAL METHODS* Discussion Leader: *Airlie McCoy* (University of Cambridge, UK) *Sasha Popov* (ESRF, Grenoble, France) BEST SAD data collection *Paul Adams* (Lawrence Berkeley Laboratory, USA) Automated structure solution with PHENIX *Kevin Cowtan* (University of York, UK) The 3 R's of automated model building: R-factors, resolution, and refinement *George Phillips* (University of Wisconsin-Madison, USA) Interpretation of electron density maps from protein crystals *CHALLENGING PROBLEMS / MEMBRANE PROTEINS * Discussion Leader: *Tom Terwilliger* (Los Alamos National Laboratory, USA) *Chris Tate* (LMB-MRC Cambridge, UK) Thermostabilisation and structure determination of a beta1 adrenergic receptor *Mike Lawrence* (The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia) Pursuit of the structure of the human insulin receptor ectodomain *Mark Mayer* (NIH, Bethesda, USA) Structure and function of allosteric ion binding sites in glutamate receptor ligand binding domains *TALKS SELECTED FROM POSTERS* *VALIDATION* Discussion Leader: *Ana Gonzales* (Stanford Synchrotron Radiation Laboratory, USA) *Gerard Kleywegt* (University of Uppsala, Sweden) Validation *Jane Richardson* (Duke University, USA) MolProbity Progress: RNA, Auto-corrections, and H redux *IMAGING METHODS OF THE FUTURE* Discussion Leader: *Raimond Ravelli* (Leiden University Medical Centre, The Netherlands) *Steve Ludtke* (Baylor College of Medicine, Houston, USA) Resolution and Molecular Motion, Frontiers in CryoEM *Carolyn Larabell*
