[ccp4bb] Phd and postdoc positions in Structural biology

[Magnus Wolf-Watz]

Hi

The Magnus Wolf-Watz lab in Umeå, Sweden has two openings in structural biology:

One PhD position directed at human protein kinases and their linkage to human 
cancer application deadline May 20

One Postdoc in structural biology of silk and cellulose modifying enzymes, 
application deadline April 15!

See below and www.biostruct.umu.se for more information

PhD position in biochemistry; structural biology of cancer linked protein 
kinases

A PhD position in biochemistry is available in the laboratory of Professor 
Magnus Wolf-Watz at the Department of Chemistry, Umeå University, Sweden. The 
PhD project is aimed at uncovering novel molecular mechanisms underlying the 
function of human protein kinases. Focus will be on two specific protein 
kinases that are intimately linked to a number of disorders in humans including 
various forms of cancer. The doctoral student will enter a multidisciplinary 
project that is built on collaborations with both Professor Kwangho Nam at 
University of Texas Arlington and with Marené Landström (Professor in pathology 
at Umeå University). The doctoral student will be trained in structural 
biology, protein production, biochemistry and biophysics and will collaborate 
with both cell biologists and computational chemists. Structural biology may go 
in any of the directions; single particle cryo EM, x-ray crystallography or 
protein NMR spectroscopy depending on the development of the research project 
and also depending on the interests of the doctoral student. The position is in 
part funded by the National Institute of Health (NIH).
2-year postdoc fellowship: Green Structural Biology in cellulose and silk 
biotechnology
An important aspect of green chemistry and a sustainable and circular economy 
is to develop environmentally friendly methodology to retrieve valuable 
chemicals from complex biomaterials. This interdisciplinary project tackles 
this challenging task by exploring the molecular mechanisms underlying 
enzymatic processing of recalcitrant natural polymers: cellulose and silk 
fibers. In the project we focus on two enzymes that bring novel functionality 
in cellulose and silk bio-processing by softening their structure and paving 
the way for further biocatalytic transformation of the fibers.
We are seeking a structural biologist with a strong background in biochemistry 
and/or protein production with different expression organisms. The structural 
biology background may be in any of the areas of NMR spectroscopy, single 
particle cryo EM or x-ray crystallography.   The successful candidate will have 
the possibility to define and shape the project dependent on background and 
ambitions and may focus on both enzymes and/or the structures of cellulose and 
silk-based biomaterials.


Please contact Magnus W-W for further information and guide to the application,


---
Dr. Magnus Wolf-Watz
Professor
Umeå University
Chemistry Department
Integrated Structural Biology (ISB), Twitter @ISB_UmU
Phone:+46 90 786 76 90
Lab Home Page: 
www.biostruct.umu.se/principal-investigators/magnus-wolf-watz/
Twitter: @watz_wolf





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[ccp4bb] PhD and Postdoc Positions in Structural Biology

[Clemens Grimm]

A PhD and a postdoc position in structural biology is available at the  
department of biochemistry at the Biocentre (head Prof. Utz Fischer)  
of the Julius Maximilians University, Wuerzburg/Germany in the field  
of RNP biochemistry.


The successful applicant will establish protocols for the isolation  
and reconstitution of preparative amounts of RNP complexes, which will  
then be characterized by cryo-electron microscopy and x-ray  
crystallography. We are looking for candidates with expertise in  
protein expression and purification and a strong interest in  
structural biochemistry. Prior knowledge of cryo electron microscopy,  
protein crystallography or biophysical methods is a plus.

Please send your application including a letter of interest,
curriculum vitae, academic certificates and the name and contact  
detail of at least one referee to


Prof. Utz Fischer/Dr. Clemens Grimm
e-mail: clemens.gr...@biozentrum.uni-wuerzburg.de
Lehrstuhl für Biochemie
Biozentrum der Universitaet Wuerzburg
Am Hubland
D-97074 Wuerzburg



--
Dr. Clemens Grimm
Institut für Biochemie
Biozentrum der Universität Würzburg
Am Hubland
D-97074 Würzburg
Germany
e-mail: clemens.gr...@biozentrum.uni-wuerzburg.de
phone : +49 0931 31 84031
-



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[ccp4bb] PhD and Postdoc Positions in Structural Biology

[Clemens Grimm]

A PhD and a postdoc position in structural biology is available at the  
department of biochemistry at the Biocentre (head Prof. Utz Fischer)  
of the Julius Maximilians University, Wuerzburg/Germany in the field  
of RNP biochemistry.


The successful applicant will establish protocols for the isolation  
and reconstitution of preparative amounts of RNP complexes, which will  
then be characterized by cryo-electron microscopy and x-ray  
crystallography. We are looking for candidates with expertise in  
protein expression and purification and a strong interest in  
structural biochemistry. Prior knowledge of cryo electron microscopy,  
protein crystallography or biophysical methods is a plus.

Please send your application including a letter of interest,
curriculum vitae, academic certificates and the name and contact  
detail of at least one referee to


Prof. Utz Fischer/Dr. Clemens Grimm
e-mail: clemens.gr...@biozentrum.uni-wuerzburg.de
Lehrstuhl für Biochemie
Biozentrum der Universitaet Wuerzburg
Am Hubland
D-97074 Wuerzburg


--
Dr. Clemens Grimm
Institut für Biochemie
Biozentrum der Universität Würzburg
Am Hubland
D-97074 Würzburg
Germany
e-mail: clemens.gr...@biozentrum.uni-wuerzburg.de
phone : +49 0931 31 84031
-

[ccp4bb] PhD and Postdoc Positions in Structural Biology of Large Macromolecular Assemblies, Basel (CH)

[Timm Maier]

Postdoctoral and PhD student positions are available in the research group of 
Timm Maier at the Biozentrum (www.biozentrum.unibas.ch/maier), University of 
Basel, Switzerland, to study giant multienzymes, large regulatory complexes and 
membrane protein assemblies.

We employ a combination of structural biology techniques, including X-ray 
crystallography, electron microscopy, XL-MS and SAXS at state-of-the-art level 
to resolve the architecture of large protein assemblies. For recent examples 
cf. Science 351, 48-52 (2016), Nature 531, 533-537(2016), Cell 160, 952-962 
(2015). Additionally, we aim to visualize dynamics of multienzyme factories and 
transient regulatory interactions in eukaryotic protein complexes. Our group is 
embedded in the focal area “Structural Biology & Biophysics” of the Biozentrum, 
which offers a stimulating interdisciplinary environment. We collaborate 
intensely with researchers in the areas of cellular signaling and infection 
biology. Our team is supported by excellent in-house core facilities for 
electron microscopy, proteomics, imaging and biophysics; dedicated large scale 
computing resources are available.  

We are looking for enthusiastic scientists who share our dedication to solving 
challenging problems in biology. Postdoc candidates should have obtained their 
PhD within the last 4 years or expect to complete their PhD soon. Ideal 
candidates are trained at state-of-the-art level in structural biology of large 
assemblies or membrane proteins using cryo-electron microscopy or X-ray 
crystallography; experience in eukaryotic protein production or multi-scale 
modelling is a plus. Postdoc candidates are expected to have demonstrated their 
scientific excellence by at least one strong published or upcoming first author 
paper.  PhD candidates should have recently obtained or be about to obtain a 
master’s degree in biological sciences including hands-on lab work in molecular 
or structural biology and should be highly motivated to pursue science. 
Salaries start at 47040CHF/year for PhD students. The Biozentrum is dedicated 
to excellence in research and education and provides outstanding support and 
training for PhD students and Postdocs (www.biozentrum.unibas.ch/education). 
Basel is an international center for biomedical research, with major academic 
institutions and research departments of leading life science companies. 
Situated in Switzerland on the borders to France and Germany along the river 
Rhine, Basel offers a high quality of living and is home to a large expat 
community.

Please note that until June 20th prospective PhD students interested in joining 
the Biozentrum could apply for a prestigious Biozentrum fellowship with 
additional benefits (www.biozentrum.unibas.ch/education/phd/fellowship-program).

Please send your application as a single pdf document including CV, publication 
record and a concise outline of prior research experience together with contact 
details of up to three references to timm.ma...@unibas.ch. Informal inquiries 
via e-mail are welcome.