[FairfieldLife] LSD: coherence??
Neural correlates of the LSD experience revealed by multimodal neuroimaging http://www.pnas.org/content/early/2016/04/05/1518377113 http://www.pnas.org/content/early/2016/04/05/1518377113 Neural correlates of the LSD experience revealed by mult... http://www.pnas.org/content/early/2016/04/05/1518377113 Author contributions: R.L.C.-H., S.M., K.M., R.L., J.E., K.D.S., R.G.W., A.F., and D.J.N. designed research; View on www.pnas.org http://www.pnas.org/content/early/2016/04/05/1518377113 Preview by Yahoo Pics in a Finnish science magazine: Lsd palauttaa aivot samanlaiseen tilaan kuin vauvana http://www.tiede.fi/artikkeli/uutiset/lsd_palauttaa_aivot_samanlaiseen_tilaan_kuin_vauvana http://www.tiede.fi/artikkeli/uutiset/lsd_palauttaa_aivot_samanlaiseen_tilaan_kuin_vauvana Lsd palauttaa aivot samanlaiseen tilaan kuin v... http://www.tiede.fi/artikkeli/uutiset/lsd_palauttaa_aivot_samanlaiseen_tilaan_kuin_vauvana Aivokuvaukset osoittavat, että lsd:n vaikutuksen aikana aivot käsittelevät näkötietoa paljon laajemmin kuin normaalisti. View on www.tiede.fi http://www.tiede.fi/artikkeli/uutiset/lsd_palauttaa_aivot_samanlaiseen_tilaan_kuin_vauvana Preview by Yahoo
[FairfieldLife] LSD - The comeback
Scientists are exploring the use of psychedelic drugs such as LSD to treat a range of ailments from depression to cluster headaches and obsessive compulsive disorder. The first clinical trial using LSD since the 1970s began in Switzerland in June. It aims to use psychedelic psychotherapy to help patients with terminal illnesses come to terms with their imminent mortality and so improve their quality of life. Another psychedelic substance, psilocybin - the active ingredient in magic mushrooms, has shown promising results in trials for treating symptoms of terminal cancer patients. And researchers are using MDMA (ecstasy) as an experimental treatment for post-traumatic stress disorder. Charles Grob, a professor of psychiatry at the Harbor-UCLA Medical Centre, is in the vanguard of the resurgence of scientific interest in psychedelics, having recently completed a trial that used psilocybin to help patients with terminal cancer come to terms with their illness. I think there's a perception these compounds hold untapped potential to help us understand the human mind, he said. The way hallucinogens such as LSD (lysergic acid diethylamide), psilocybin and mescaline (the active ingredient in the peyote cactus) act on the brain is reasonably well understood by scientists. The drugs stick to chemical receptors on nerve cells that normally bind the neurotransmitter serotonin, which affects a broad range of brain activities. But how this leads to the profoundly altered states of consciousness, perception and mood that typically accompany a trip is not known. Prof Roland Griffiths at the Johns Hopkins School of Medicine in Baltimore Maryland recently published a study of 36 healthy volunteers who were given psilocybin and then observed in the lab. The participants' ages ranged from 24 to 64 and none had taken hallucinogens before. When the group were interviewed again 14 months later 58% said they rated the experience as being among the five most personally meaningful of their lives, 67% said it was in their top five spiritual experiences, and 64% said it had increased their well- being or life satisfaction. The working hypothesis is that if psilocybin or LSD can occasion these experiences of great personal meaning and spiritual significance ... then it would allow [patients with terminal illnesses] hopefully to face their own demise completely differently - to restructure some of the psychological angst that so often occurs concurrently with severe disease, said Griffiths. So by expanding their consciousness during a session on the drug, the patient is able to comprehend their thoughts and feelings from a new perspective. This can lead to a release of negative emotions that leaves them in a much more positive state of mind. Case study Edited extract from an interview Pamela Sakuda did for researchers on the psilocybin experience: As the session began, and as it built up, I felt this lump of emotions welling up and firming up almost like an entity. I started to cry a little. Then it started to dissipate and I started to look at it differently and I think that is the beauty of being able to expand your consciousness. I don't think the drug is the cause of these things. I think it is a catalyst that allows you to release your own thoughts and feelings from some place that you have bound them to very tightly. I began to realise that all of this negative fear and the guilt was such a hindrance to making the most of and enjoying the healthy time that I'm having - however long it may be. I was not utilising it to the best and enjoying my life because I was so afraid of what wasn't there yet. These substances occur in our natural world and people have been using them for thousands of years to treat physical illness, to treat social and behavioural problems. Read whole thing: http://www.guardian.co.uk/science/2008/aug/12/medicalresearch.drugs
[FairfieldLife] 'LSD and The Magical Mystery Tour'
Albert Hoffman and LSD LSD May Have Been One of the Bigger Medical Brearkthrouth's in the 20th Century. It Did Seem to Help Sgt. Pepper. Albert Hofmann (b.1/11/1906 – d.4/29/2008) died this week. He was a Swiss scientist best known forhaving been the first to discover, actuallyinjest and describe the psychedelic effects of Lysergic AcidDiethylamide (LSD). Hofmann was born in the quiet town ofBaden Switzerland, and studied chemistry at the Univ. of Zurich. Hismain interest was the chemistry of plants and animals, and he laterconducted important research regarding the chemical structure of thecommon animal substance chitin for which he received his Ph.D. Hofmannjoined the pharmaceutical-chemical department of Sandoz Laboratories(now Novartis). He began studying the fungus ergot as part of a programto purify and synthesize active constituents for use aspharmaceuticals. While researching lysergic acid derivatives, Hofmannfirst synthesized LSD-25 in 1938. It was set aside for five years,until April 16, 1943, when Hofmann decided to take another look at it.While re-synthesizing LSD, he accidentally absorbed a small quantitythrough his fingertips and discovered its powerful effects before hisbicycle ride home. Three days later, Hofmann deliberately consumed 250micrograms of LSD. This was followed by a series of self-experimentsconducted by Hofmann and his colleagues. He first wrote about theseexperiments on April 22 of that year. BRAIN/NEUROLOGIC FUNCTION:There are two main neurotransmitters in the brain; Serotonin andDopamine. Interestingly, LSD is similar in chemical structure toSerotonin and in effect, acts as a neurotransmitter once inside thebrain. Oddly, it specifically acts as a Serotonin blocker and reactsmore highly with Dopamine receptors in the brain. LSD, once absorbedfiltrates out of the blood quickly and tends to deposit directly intothe midbrain. The end result of all of this is Hyperactivity andsimulated pyschosis. Often used as a therapeutic remedy, medicine istaking a longer more detailed look at this often demonized drug. It isin this arena, psycho therapy, that LSD may still find a purpose. EFFECTS:LSD has numerous measurable effects on the brain. It produces slightchanges in the EEG, usually with decreased amplitude and increasedfrequency of brainwaves (Stafford 1992). Generally there is also adecrease in the alpha rhythm, though in some cases however, there is anincrease. LSD causes many chemical changes within the brain, most ofthem in the midbrain, which regulates awareness and modulates emotionalresponsiveness. Recent attention has focused on substantialconcentrations of LSD found in the brainstem and in the dopaminereceptor system, both responsible for more complex experiences. Under the influence of LSD, data processing in the brain's cerebral cortex was shifted, from the more analytical left hemisphere to the visuo-spatial right hemisphere. This may explain how apsychedelic like LSD increases the scope of the mind, bringsartistic, creative, rhythmic and problem solving abilities to the foreand evokes phenomena that Freud referred to as manifestations of theunconscious. Increases in mental power may also be attributed to theactivation of spatial centers. LSD and other psychedelics could beconsidered deliberate and unconscious agents of the right lobe in thissense. There is a peculiar effect of LSD on thetransmission of sensory impulses to the brain, which has long beendemonstrated in laboratory experiments on sensory response of animalsunder the influence of LSD (Leicht 1996). Electrical measurements alongthe optic nerve show that an intensified impulse is received from theretina, due to changes in the receptivity of the visual system. Theelectrical impulses produced continue to increase under LSD influenceand to become more distorted as they travel along the optic pathway tothe brain. This is an indication that LSD has a unique physiologicaleffect on the geniculate body and the optic radiation pathway of thevisual system. The character of the impulses received and transmittedby one organ are found to be affected by the impulses to the other.Sights reaching the brain from the eye are changed by sounds, andsounds are changed by what the eye apparently sees. LSD users may see music, hear color, and feel visual images. These mixed messages to the brain exhibit the phenomenon called in psychology commonly called synesthesia. PSYCHOLOGICAL EFFECTS: Thereare many psychological effects of LSD on the mind includinghallucinations, depersonalization, reliving of repressed memories, moodswings, euphoria, megalomania, schizophrenic-like states, reduceddefenses, and subjectivity to the power of suggestion. Thepsychological effects of LSD may be generalized by three categories:changes in sensation and perception; emotionality; effects on thinking.The function of perceiving, organizing, and interpreting senseimpressions from
[FairfieldLife] LSD chemist dies at 102
Dr. Hofmann first synthesized the compound lysergic acid diethylamide in 1938 but did not discover its psychopharmacological effects until five years later, when he accidentally ingested the substance that became known to the 1960s counterculture as acid. He then took LSD hundreds of times, but regarded it as a powerful and potentially dangerous psychotropic drug that demanded respect. More important to him than the pleasures of the psychedelic experience was the drug's value as a revelatory aid for contemplating and understanding what he saw as humanity's oneness with nature. That perception, of union, which came to Dr. Hofmann as almost a religious epiphany while still a child, directed much of his personal and professional life. Dr. Hofmann was born in Baden, a spa town in northern Switzerland, on Jan. 11, 1906, the eldest of four children. His father, who had no higher education, was a toolmaker in a local factory, and the family lived in a rented apartment. But Dr. Hofmann spent much of his childhood outdoors. He would wander the hills above the town and play around the ruins of a Hapsburg castle, the Stein. It was a real paradise up there, he said in an interview in 2006. We had no money, but I had a wonderful childhood. It was during one of his ambles that he had his epiphany. It happened on a May morning I have forgotten the year but I can still point to the exact spot where it occurred, on a forest path on Martinsberg above Baden, he wrote in LSD: My Problem Child. As I strolled through the freshly greened woods filled with bird song and lit up by the morning sun, all at once everything appeared in an uncommonly clear light. It shone with the most beautiful radiance, speaking to the heart, as though it wanted to encompass me in its majesty. I was filled with an indescribable sensation of joy, oneness and blissful security. (more) http://www.nytimes.com/2008/04/30/world/europe/30hofmann.html
[FairfieldLife] LSD champ Leary's wild life
http://www.nytimes.com/2006/06/25/books/review/25sante.html Yahoo! Groups Sponsor ~-- See what's inside the new Yahoo! Groups email. http://us.click.yahoo.com/2pRQfA/bOaOAA/yQLSAA/UlWolB/TM ~- To subscribe, send a message to: [EMAIL PROTECTED] Or go to: http://groups.yahoo.com/group/FairfieldLife/ and click 'Join This Group!' Yahoo! Groups Links * To visit your group on the web, go to: http://groups.yahoo.com/group/FairfieldLife/ * To unsubscribe from this group, send an email to: [EMAIL PROTECTED] * Your use of Yahoo! Groups is subject to: http://docs.yahoo.com/info/terms/
[FairfieldLife] LSD??
THE STARS THAT PLAY WITH LAUGHING SAM'S DICE LYRICS Lyrics - Jimi Hendrix Lyrics - THE STARS THAT PLAY WITH LAUGHING SAM'S DICE Lyrics THE STARS THAT PLAY WITH LAUGHING SAM'S DICE Lyrics Artist(Band):Jimi Hendrix THE STARS THAT PLAY WITH LAUGHING SAM'S DICE Lyrics Send Jimi Hendrix polyphonic ringtone to your cell phone STARS UP ABOVE THAT PLAY WITH LAUGHING SAM'S DICE Gave me this fear that it weren't the world for us THE ZODIAC sign was gleaming and came THROUGH THE SKIES IT WILL HAPPEN SOON, FOR YOU All right everybody let's get together now AND A WAY WE GO YEAH THANK YOU VERY MUCH, come in, thank you, thank you THANK YOU VERY MUCH, right now WE'D LIKE TO BRING TO YOU OUR ah one and only FREINDLY NEIGHBORHOOD EXPERIENCE Makers, Yeah All RIGHT NOW LISTEN yeah baby, thank you very much THE MILKY WAY EXPRESS IS LOADED, ALL ABOARD I PROMISE EACH AND EVERY ONE of YOU YOU WON'T BE BORED Now let's take time to keep everybody honest and straight WHAT I'M REALLY thinking ABOUT IS MY BRAND-NEW PAIR OF BUTTERFLY ROLLER SKATES Owww! Thank you, thank you And I watch them ride! Yeah Um, I meant to say that, there'll be no throwing cigarette butts out the window No throwing cigarette butts out the window, thank you thank you I hope all of you brought your tooth...brush Yeah NOW TO the RIGHT YOU'LL SEE SATURN Outta sight, really outta sight And IF YOU LOOK TO THE LEFT, YOU'LL SEE MARS Yeah, Yeah I HOPE all of you BROUGHT YOUR PARACHUTES WITH YOU HEY, Hey LOOK OUT! LOOK OUT FOR THAT DOOR! DON'T OPEN THAT DOOR! DON'T OPEN THAT DOOR! OH, WELL THAT'S THE WAY IT GOES And now we're coming through the ah, milky way expressway Yeah With your corn flakes, stuff like that, Milky way, yeah HEY, EVERYTHING IS ALL RIGHT, and out of sight Owww! Uh no, no (laughs) If you look around you you will see a few minds being blown Exactly, exactly baby Yeah I hope your all enjoying your ride I am! Aww! Yeah, (I forgot to say that) Goodbye Yahoo! Groups Sponsor ~-- Join modern day disciples reach the disfigured and poor with hope and healing http://us.click.yahoo.com/lMct6A/Vp3LAA/i1hLAA/UlWolB/TM ~- To subscribe, send a message to: [EMAIL PROTECTED] Or go to: http://groups.yahoo.com/group/FairfieldLife/ and click 'Join This Group!' Yahoo! Groups Links * To visit your group on the web, go to: http://groups.yahoo.com/group/FairfieldLife/ * To unsubscribe from this group, send an email to: [EMAIL PROTECTED] * Your use of Yahoo! Groups is subject to: http://docs.yahoo.com/info/terms/
