Re: [Felvtalk] FeLv Positive cat

[Margo]

I went thru the lymph node thing with one cat three years ago. All external 
nodes were the size of a golfball. His were so bad internally that they 
obstructed his bowel. He was in a household with FeLV+s, so we assumed 
lymphosarcoma. I took him in, and it was my first contact with a new Vet. I 
told her I had no desire to put a dying cat thru very much, if she could just 
relieve the constipation, and try to shrink the nodes, I'd just take him home 
and make him comfortable. She (surprisingly, to me) didn't quibble, gave him an 
enema, prescribed an antibiotic (I chose Zenequin), and a course of 
prednisolone. He recovered completely, and there's never been a recurrence. 

I don't know if he's FeLV+. None of us expected him to live, so no bloodwork 
was done. 

Just my experience.

Margo


-Original Message- 
>From: dlg...@windstream.net
>Sent: Feb 25, 2017 9:15 AM
>To: Molly Mou , felvtalk@felineleukemia.org
>Subject: Re: [Felvtalk] FeLv Positive cat
>
>I haave had no problems with this, all I can offer is prayer.
>
> Molly Mou  wrote: 
>>  I am new to the list. Three weeks ago my 5-year old Miakitty was diagnosed 
>> with FeLv. The ELISA test showed slightly + for FeLv. Itook her to the vet’s 
>> initially because her lymph nodes were raging – all ofthem premandibular, 
>> prescapular, inguinal all the way to the popliteals wereenlarged. A needle 
>> aspirate of the lymph nodes result was hyperplasia,no lymphosarcoma. White 
>> blood cell count was normal, but she was anemic, butnot to the point of 
>> needing a transfusion.I was devastated and stunned at this diagnosis because 
>> she(the whole litter) was tested as kittens for FIV and FeLv and were 
>> negative. Myvet said the disease can stay in the bone marrow. I have her 
>> brother who isasymptomatic – confusing. I haven’t had him tested yet for 
>> FeLv yet.My vet recommended treatment with Immunoregulin. Theprotocol per 
>> Plumb’s is an IV injection twice weekly for two weeks, then 1injection once 
>> weekly for 21 weeks. She is now in her 4th week oftreatment. For the first 
>> two weeks, her lymph nodes decreased and becamesofter. But after the 2nd 
>> week her lymph nodes are raging againdespite the treatments. She is eating 
>> well, but not very active. Has anyone had experience with this treatment or 
>> any othertreatment(s) or advice to help my little girl? Thanks in advance,  
>> Pat Peterson
>
>
>___
>Felvtalk mailing list
>Felvtalk@felineleukemia.org
>http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org

___
Felvtalk mailing list
Felvtalk@felineleukemia.org
http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org

Re: [Felvtalk] FeLv Positive cat

[Amani Oakley]

Hi Molly

I tried Immunoregulin for a long time with my FeLV little boy, but it was 
completely ineffective. You need to be doing regular (weekly or every other 
week) blood testing, to monitor whether the Immunoregulin is helping or not.

If not, then don’t run through the full 21 weeks. There would be no point and 
you will waste valuable time while she worsens.

I had good luck using a combination of Doxycycline (1/2 100 mg twice a day) 
plus Winstrol (1 mg x2 day) plus prednisone/prednisolone (1/2 5 mg tablet x2 a 
day). Even on this protocol, I recommend close weekly or bi-weekly monitoring 
so you can see if you start getting a rise in the red cell indices, etc. Don’t 
let your vet talk you out of one or another of these medications. You can’t 
substitute another antibiotic for the Doxycycline, for example. Doxycycline has 
anti-RNA properties (which allows it to interfere with the replication of 
viruses when other antibiotics don’t do this.)

Some people in this group have also reported excellent results with “Zander’s 
Protocol” while others have not. I am hypothesizing that this may be due to the 
fact that it appears there may be as many as five different strains of the 
virus, so perhaps the different strains respond or don’t respond to certain 
things. The other thing that may affect outcome is timing. The virus shuts down 
the bone marrow by killing or taking over the cells in the bone marrow. At some 
point, there will be little in the bone marrow to turn back on (which it 
appears the Winstrol can do in some instances).

Amani

P.S. – For those of you keeping score, I have corrected my previous description 
of Zander’s Protocol because I found an old pill bottle and realized I had been 
giving him ½ a 100 mg Doxy tablet twice a day, not a ¼ tablet as I had 
previously reported. Sorry for any confusion.

From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of Molly 
Mou
Sent: February-24-17 9:57 PM
To: felvtalk@felineleukemia.org
Subject: [Felvtalk] FeLv Positive cat

I am new to the list. Three weeks ago my 5-year old Mia kitty was diagnosed 
with FeLv. The ELISA test showed slightly + for FeLv. I took her to the vet’s 
initially because her lymph nodes were raging – all of them premandibular, 
prescapular, inguinal all the way to the popliteals were enlarged.
A needle aspirate of the lymph nodes result was hyperplasia, no lymphosarcoma. 
White blood cell count was normal, but she was anemic, but not to the point of 
needing a transfusion.
I was devastated and stunned at this diagnosis because she (the whole litter) 
was tested as kittens for FIV and FeLv and were negative. My vet said the 
disease can stay in the bone marrow. I have her brother who is asymptomatic – 
confusing. I haven’t had him tested yet for FeLv yet.
My vet recommended treatment with Immunoregulin. The protocol per Plumb’s is an 
IV injection twice weekly for two weeks, then 1 injection once weekly for 21 
weeks. She is now in her 4th week of treatment.
For the first two weeks, her lymph nodes decreased and became softer. But after 
the 2nd week her lymph nodes are raging again despite the treatments. She is 
eating well, but not very active.
Has anyone had experience with this treatment or any other treatment(s) or 
advice to help my little girl?

Thanks in advance,

Pat Peterson
___
Felvtalk mailing list
Felvtalk@felineleukemia.org
http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org

Re: [Felvtalk] FeLv Positive cat

[Katherine K.]

I suggest getting her brother tested ASAP and subsequently vaccinated
against FeLV if he is negative.

On Feb 25, 2017 9:57 AM, "Sandy"  wrote:

> this is from previous posts - get your kitty cat to a vet - hopefully -
> who will not be afraid to "go outside" the box.
>
> Winstrol – 1 mg twice a day
>
>
>
> Doxycycline – 1/5 to ¼ tablet (100 mg) twice a day
>
>
>
> Prednisolone – ½ 5 mg tablet, twice a day
>
>
>
>
>
> If there are problems with the intestines (vomiting, constipation, slow
> moving stools, stools of large diameters, all of which might be indicative
> of the effect of the virus on the intestines) you can try adding ¼ tablet
> of apometocloprimide.
>
>
>
> If the haematocrit level is REALLY REALLY low – like below 5-8, you might
> consider starting the Winstrol at 2 mg twice a day for a week, to try and
> kickstart things quickly, but given that there is going to be a likely
> increase in liver enzymes with the use of Winstrol, recognize that this
> might also increase the liver enzymes faster.
>
>
>
>  Hope this helps!  Amani
>
>
>
>  *From:* Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] *On Behalf
> Of *gary
> *Sent:* January-27-17 4:04 PM
> *To:* felvtalk@felineleukemia.org
> *Subject:* Re: [Felvtalk] My baby recently diagnosed with FeLV
>
>  Amani,
>
> Could you please give the dosages used for Zander's Protocol? I know they
> must have been previously given, but I cannot seem to find them.
>
> Thanks,   Gary
>
>  On 9/16/2016 8:52 AM, Amani Oakley wrote:
>
> Hi Sherri
>
>
>
> I hope you got some good news today. However, as you know, my experience
> is that the Winstrol needs to be used long term before the red cells are
> back into the normal range. I continue to recommend use of the Doxycyline
> to interfere with viral RNA synthesis. The Winstrol does not attack the
> virus, though I believe it makes the cat stronger overall and able to fight
> back. But at the outset of the treatment regime, I believe you must have
> the Doxycycline on board to try and reduce the viral load, or at least,
> keep it from rising.
>
>
>
> Amani
>
> ___
> Felvtalk mailing list
> Felvtalk@felineleukemia.org
> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
>
>
>
> Hi Liz
>
>
>
> The only thing that works to turn back on red cell production is Winstrol
> (Stanazolol). It is an ANABOLIC steroid (as opposed to most steroids we are
> used to getting, like prednisone, which is a corticosteroid.
>
>
>
> Anabolic steroids are ones which build muscle, tissue, etc.
>
>
>
> Adding Winstrol to the combination of medication you have your cat on
> right now, would be the best thing to do. The Doxycycline acts to slow down
> or inhibit the reproduction of the FeLV virus by interfering the RNA
> duplication. The prednisone is helpful in keeping inflammation at bay, but
> neither of these helps to increase the red cells. The Winstrol acts
> directly and very quickly on the bone marrow and seems to get red cells
> generated again, quite promptly. At least it did for my Zander, and I have
> been contacted directly by several people from this group, who have
> reported to me that they also saw almost immediate (within 3 days) evidence
> of their cats’ gums/ears/pads pinkening up.
>
>
>
> The problem is that Winstrol is a controversial drug because it is also
> what professional athletes use to get bigger, stronger and faster. Quite
> unfortunately (since none of our cats are entering the Olympics) that
> association with doping scandals has cast a shadow on its use in both
> animal and people medicine. In human medicine, it is the only drug found to
> be effective in treating hereditary angioedema and anemia.
>
>
>
> Here is a blurb I found about it:
>
>
>
> Winstrol was first invented in 1959. Soon after that, the UK based
> Winthrop Laboratories created a prescription medicine from it. Later, in
> 1961, Winthrop’s patent was bought by the US based Sterling that started
> manufacturing and selling the drug in the American markets.
>
> In the beginning, Winstrol was used for a variety of medical reasons. But
> later, by the 1970s, the FDA had restricted its use to only promoting
> growth and treating osteoporosis. In the 1980s, there was a termination of
> the manufacture of anabolic steroids in the American market. But Winstrol
> was among those steroids which not only survived, but thrived in the 1980s
> and 1990s. During this period, its use was reinforced as a cure for anemia
> – as it had the power to boost red blood cell count, and was used as a
> treatment for facial swelling or angioedema.
>
> When the manufacture of Winstrol was finally discontinued, Ovation
> Pharmaceuticals bought the rights to manufacture it, in 2003. However,
> Ovation Pharmaceuticals have ceased their operations now, so the Winstrol
> products available today in the American markets are only generic and not
> pharmaceutical grade. Outside the USA, 

Re: [Felvtalk] FeLv Positive cat

[Sandy]

this is from previous posts - get your kitty cat to a vet - hopefully - who 
will not be afraid to "go outside" the box. 



Winstrol – 1 mg twice a day 



Doxycycline – 1/5 to ¼ tablet (100 mg) twice a day 



Prednisolone – ½ 5 mg tablet, twice a day 





If there are problems with the intestines (vomiting, constipation, slow moving 
stools, stools of large diameters, all of which might be indicative of the 
effect of the virus on the intestines) you can try adding ¼ tablet of 
apometocloprimide. 



If the haematocrit level is REALLY REALLY low – like below 5-8, you might 
consider starting the Winstrol at 2 mg twice a day for a week, to try and 
kickstart things quickly, but given that there is going to be a likely increase 
in liver enzymes with the use of Winstrol, recognize that this might also 
increase the liver enzymes faster. 



Hope this helps! Amani 



From: Felvtalk [ mailto:felvtalk-boun...@felineleukemia.org ] On Behalf Of gary 
Sent: January-27-17 4:04 PM 
To: felvtalk@felineleukemia.org 
Subject: Re: [Felvtalk] My baby recently diagnosed with FeLV 

Amani, 

Could you please give the dosages used for Zander's Protocol? I know they must 
have been previously given, but I cannot seem to find them. 

Thanks, Gary 

On 9/16/2016 8:52 AM, Amani Oakley wrote: 

Hi Sherri 



I hope you got some good news today. However, as you know, my experience is 
that the Winstrol needs to be used long term before the red cells are back into 
the normal range. I continue to recommend use of the Doxycyline to interfere 
with viral RNA synthesis. The Winstrol does not attack the virus, though I 
believe it makes the cat stronger overall and able to fight back. But at the 
outset of the treatment regime, I believe you must have the Doxycycline on 
board to try and reduce the viral load, or at least, keep it from rising. 



Amani 

___ 
Felvtalk mailing list 
Felvtalk@felineleukemia.org 
http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org 



Hi Liz 



The only thing that works to turn back on red cell production is Winstrol 
(Stanazolol). It is an ANABOLIC steroid (as opposed to most steroids we are 
used to getting, like prednisone, which is a corticosteroid. 



Anabolic steroids are ones which build muscle, tissue, etc. 



Adding Winstrol to the combination of medication you have your cat on right 
now, would be the best thing to do. The Doxycycline acts to slow down or 
inhibit the reproduction of the FeLV virus by interfering the RNA duplication. 
The prednisone is helpful in keeping inflammation at bay, but neither of these 
helps to increase the red cells. The Winstrol acts directly and very quickly on 
the bone marrow and seems to get red cells generated again, quite promptly. At 
least it did for my Zander, and I have been contacted directly by several 
people from this group, who have reported to me that they also saw almost 
immediate (within 3 days) evidence of their cats’ gums/ears/pads pinkening up. 



The problem is that Winstrol is a controversial drug because it is also what 
professional athletes use to get bigger, stronger and faster. Quite 
unfortunately (since none of our cats are entering the Olympics) that 
association with doping scandals has cast a shadow on its use in both animal 
and people medicine. In human medicine, it is the only drug found to be 
effective in treating hereditary angioedema and anemia. 



Here is a blurb I found about it: 



Winstrol was first invented in 1959. Soon after that, the UK based Winthrop 
Laboratories created a prescription medicine from it. Later, in 1961, 
Winthrop’s patent was bought by the US based Sterling that started 
manufacturing and selling the drug in the American markets. 

In the beginning, Winstrol was used for a variety of medical reasons. But 
later, by the 1970s, the FDA had restricted its use to only promoting growth 
and treating osteoporosis. In the 1980s, there was a termination of the 
manufacture of anabolic steroids in the American market. But Winstrol was among 
those steroids which not only survived, but thrived in the 1980s and 1990s. 
During this period, its use was reinforced as a cure for anemia – as it had the 
power to boost red blood cell count, and was used as a treatment for facial 
swelling or angioedema. 

When the manufacture of Winstrol was finally discontinued, Ovation 
Pharmaceuticals bought the rights to manufacture it, in 2003. However, Ovation 
Pharmaceuticals have ceased their operations now, so the Winstrol products 
available today in the American markets are only generic and not pharmaceutical 
grade. Outside the USA, however, several large brands still manufacture and 
sell Winstrol. 

Genuine Stanozolol can be distinguished in water suspensions because it 
separates from the liquid into micrometer particles. These particles will fall 
to the bottom if the container is not disturbed for a few hours. The crystals 
have a milky 

Re: [Felvtalk] FeLv Positive cat

[dlgegg]

I haave had no problems with this, all I can offer is prayer.

 Molly Mou  wrote: 
>  I am new to the list. Three weeks ago my 5-year old Miakitty was diagnosed 
> with FeLv. The ELISA test showed slightly + for FeLv. Itook her to the vet’s 
> initially because her lymph nodes were raging – all ofthem premandibular, 
> prescapular, inguinal all the way to the popliteals wereenlarged. A needle 
> aspirate of the lymph nodes result was hyperplasia,no lymphosarcoma. White 
> blood cell count was normal, but she was anemic, butnot to the point of 
> needing a transfusion.I was devastated and stunned at this diagnosis because 
> she(the whole litter) was tested as kittens for FIV and FeLv and were 
> negative. Myvet said the disease can stay in the bone marrow. I have her 
> brother who isasymptomatic – confusing. I haven’t had him tested yet for FeLv 
> yet.My vet recommended treatment with Immunoregulin. Theprotocol per Plumb’s 
> is an IV injection twice weekly for two weeks, then 1injection once weekly 
> for 21 weeks. She is now in her 4th week oftreatment. For the first two 
> weeks, her lymph nodes decreased and becamesofter. But after the 2nd week her 
> lymph nodes are raging againdespite the treatments. She is eating well, but 
> not very active. Has anyone had experience with this treatment or any 
> othertreatment(s) or advice to help my little girl? Thanks in advance,  Pat 
> Peterson


___
Felvtalk mailing list
Felvtalk@felineleukemia.org
http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org