[Freesurfer] Post-doctoral Research Position at the Yale Alzheimer's Disease Research Unit

2019-04-09 Thread Adam Mecca
External Email - Use Caution

The Yale University Alzheimer’s Disease Research Unit and the Yale PET
Center has an opening for a highly qualified and motivated individual at
the post-doctoral level to work on research involving the development of
analysis techniques integrating human imaging data including PET and fMRI
for NIH-funded studies and clinical trials in Alzheimer’s disease.
Applicants must have obtained a Ph.D. in neuroscience, biomedical
engineering, or a related field.

Qualifications:
Strong experimental, analytical, and programming skills are essential.
Experience in fMRI, image analysis, algorithm development, and biological
applications is highly desirable. The selected candidate will work under
the direction of Drs. Christopher van Dyck and Adam Mecca.

The successful candidate should have a Ph.D. or an M.D./Ph.D. with at least
three years of experience in fMRI and/or PET imaging.

Application Instructions:
Interested individuals should email a CV to adam.me...@yale.edu.
Adam Mecca, M.D. Ph.D.
Yale School of Medicine, Department of Psychiatry
Geriatric Psychiatry and the Alzheimer's Disease Research Unit
Tel: (203) 764-8100
Fax: (203) 764-8111
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[Freesurfer] Image Analyst Position at the Yale Alzheimer's Disease Research Unit

2019-04-10 Thread Adam Mecca
External Email - Use Caution

The Yale University Alzheimer’s Disease Research Unit at Yale University
School of Medicine has an opening for a highly qualified and motivated
individual to work on research involving the development of analysis
techniques integrating human imaging data including PET and fMRI for
NIH-funded studies and clinical trials in Alzheimer’s disease. Applicants
must have obtained a Master’s Degree or a Bachelor’s Degree with
significant experience in neuroimaging analysis.

Qualifications:
Strong analytical, and programming skills are essential. Experience in
fMRI, image analysis, algorithm development, and biological applications is
highly desirable. The selected candidate will work under the direction of
Drs. Christopher van Dyck and Adam Mecca.

The successful candidate should have a Master’s Degree or a Bachelor’s
Degree with at least three years of experience in fMRI and/or PET imaging.

Application Instructions:
Interested individuals should email a CV to adam.me...@yale.edu.
Adam Mecca, M.D. Ph.D.
Yale School of Medicine, Department of Psychiatry
Geriatric Psychiatry and the Alzheimer's Disease Research Unit
Tel: (203) 764-8100
Fax: (203) 764-8111
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[Freesurfer] Post-doctoral Research Position at the Yale Alzheimer's Disease Research Unit

2019-06-22 Thread Adam Mecca
External Email - Use Caution

The Yale University Alzheimer’s Disease Research Unit and the Yale PET
Center has an opening for a highly qualified and motivated individual at
the post-doctoral level to work on research involving the development of
analysis techniques integrating human imaging data including PET and fMRI
for NIH-funded studies and clinical trials in Alzheimer’s disease.
Applicants must have obtained a Ph.D. in neuroscience, biomedical
engineering, or a related field.

Qualifications:
Strong experimental, analytical, and programming skills are essential.
Experience in fMRI, image analysis, algorithm development, and biological
applications is highly desirable. The selected candidate will work under
the direction of Drs. Christopher van Dyck and Adam Mecca.

The successful candidate should have a Ph.D. or an M.D./Ph.D. with at least
three years of experience in fMRI and/or PET imaging.

Application Instructions:
Interested individuals should email a CV to adam.me...@yale.edu.
Adam Mecca, M.D. Ph.D.
Yale School of Medicine, Department of Psychiatry
Geriatric Psychiatry and the Alzheimer's Disease Research Unit
Tel: (203) 764-8100
Fax: (203) 764-8111
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[Freesurfer] dt_recon error: MatrixReadTxt: could not scan value [1][1]

2018-01-19 Thread Adam Mecca
Hello FreeSurfer Developers,

I'm trying to pre-process some diffusion data based on the tutorial:
https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/DiffusionV6.0

I am getting the following warning followed by the program hanging

--
Creating output directory /home1/am2359/fs6_data/fpeb_app_fs/fpeb001/dtrecon
Loading y from
/home1/am2359/fs6_data/fpeb_app_fs/fpeb001/dtrecon/dwi-ec.nii.gz
   ... done reading.
MatrixReadTxT: could not scan value [1][1]

WARNING: matlab elment type is 1869357167, which is not a matrix.
could not allocate 543518770 x 1683973236 matrix

Cannot allocate memory
unsupported matlab format 1678398324 (unknown)

Cannot allocate memory
--

I would greatly appreciate your assistance.

1) FreeSurfer version: freesurfer-Linux-centos6_x86_64-stable-pub-v6.0.0
2) Platform: CentOS release 6.9 (Final)
3) uname -a: Linux ariespet.med.yale.edu 2.6.32-696.el6.x86_64 #1 SMP Tue
Mar 21 19:29:05 UTC 2017 x86_64 x86_64 x86_64 GNU/Linux
4) dt_recon.log: see attached

Thank you, Adam
dt_recon logfile
Fri Jan 19 20:58:24 EST 2018
VERSION $Id: dt_recon,v 1.23 2015/12/09 20:02:53 zkaufman Exp $
setenv SUBJECTS_DIR /home1/am2359/fs6_data/fpeb_app_fs
cd /home1/am2359/Desktop
/home1/am2359/freesurfer_6/bin/dt_recon --i /home1/am2359/fs6_data/fpeb_app_dicom/fpeb001/3d_dicom/MR.1.3.12.2.1107.5.2.32.35071.2015070812382834753264293 --s fpeb001 --o /home1/am2359/fs6_data/fpeb_app_fs/fpeb001/dtrecon
ariespet.med.yale.edu
am2359
/pet/apps/fsl5.0/bin/eddy_correct
ECRefTP 0
#@#---
Converting input
Fri Jan 19 20:58:24 EST 2018
cd /home1/am2359/Desktop
mri_convert /home1/am2359/fs6_data/fpeb_app_dicom/fpeb001/3d_dicom/MR.1.3.12.2.1107.5.2.32.35071.2015070812382834753264293 /home1/am2359/fs6_data/fpeb_app_fs/fpeb001/dtrecon/dwi.nii
mri_convert.bin /home1/am2359/fs6_data/fpeb_app_dicom/fpeb001/3d_dicom/MR.1.3.12.2.1107.5.2.32.35071.2015070812382834753264293 /home1/am2359/fs6_data/fpeb_app_fs/fpeb001/dtrecon/dwi.nii 
$Id: mri_convert.c,v 1.226 2016/02/26 16:15:24 mreuter Exp $
reading from /home1/am2359/fs6_data/fpeb_app_dicom/fpeb001/3d_dicom/MR.1.3.12.2.1107.5.2.32.35071.2015070812382834753264293...
Getting Series No 
INFO: Found 2584 files in /home1/am2359/fs6_data/fpeb_app_dicom/fpeb001/3d_dicom
INFO: Scanning for Series Number 6
Scanning Directory 
INFO: found 1664 files in series
INFO: loading series header info.

RunNo = 5
INFO: sorting.
sdfiSameSlicePos() eps = 0.01
INFO: (128 128  64), nframes = 26, ismosaic=0
sdfi->UseSliceScaleFactor 0
datatype = 4, short=4, float=3
PE Dir COL COL
AutoAlign matrix detected 
AutoAlign Matrix - 
 1.0   0.0   0.0   0.0;
 0.0   1.0   0.0   0.0;
 0.0   0.0   1.0   0.0;
 0.0   0.0   0.0   1.0;

FileName 		/home1/am2359/fs6_data/fpeb_app_dicom/fpeb001/3d_dicom/MR.1.3.12.2.1107.5.2.32.35071.2015070812364240080860825
Identification
	NumarisVersyngo MR B17
	ScannerModel  TrioTim 
	PatientName   FPEB001 
Date and time
	StudyDate 20150708
	StudyTime 120054.296000 
	SeriesTime123644.50 
	AcqTime   123641.007500 
Acquisition parameters
	PulseSeq  ep_b0 
	Protocol  ep2d_dti_1b0_25d
	PhEncDir  COL
	EchoNo1
	FlipAngle 90
	EchoTime  85
	InversionTime -1
	RepetitionTime7900
	PhEncFOV  256
	ReadoutFOV256
Image information
	RunNo 5
	SeriesNo  6
	ImageNo   1
	NImageRows128
	NImageCols128
	NFrames   26
	SliceArraylSize   64
	IsMosaic  0
	ImgPos128.4139 158.0412 -61.9693 
	VolRes  2.   2.   2. 
	VolDim128  128   64 
	Vc -1.  -0.   0. 
	Vr -0.  -1.   0. 
	Vs -0.  -0.   1. 
	VolCenter   0.4139  30.0412   2.0307 
	TransferSyntaxUID 1.2.840.10008.1.2.1
UseSliceScaleFactor 0 (slice 0: 1)
IsDWI = 1
INFO: no Siemens slice order reversal detected (good!). 
TR=7900.00, TE=85.00, TI=-1.00, flip angle=90.00
i_ras = (-1, -0, 0)
j_ras = (-0, -1, 0)
k_ras = (-0, -0, 1)
writing to /home1/am2359/fs6_data/fpeb_app_fs/fpeb001/dtrecon/dwi.nii...
Saving bvals and bvecs


cd /home1/am2359/Desktop
mri_probedicom --i /home1/am2359/fs6_data/fpeb_app_dicom/fpeb001/3d_dicom/MR.1.3.12.2.1107.5.2.32.35071.2015070812382834753264293
Manufacturer SIEMENS 
ScannerModel TrioTim 
SoftwareVersion syngo MR B17
ScannerSerialNo 35071 
Institution Yale University School of Medicine
SeriesDescription ep2d_dti_1b0_25d
StudyUID 1.3.12.2.1107.5.2.32.35071.301507081121329210013
StudyDate 20150708
StudyTime 120054.296000 
PatientName FPEB001 
SeriesNo 6 
ImageNo 887 
AcquisitionType 2D
ImageType ORIGINAL\PRIMARY\DIFFUSION\NONE\ND
ImagingFrequency 123.165588
PixelFrequency 1776
ImagedNucleus 1H
EchoNumber 1 
FieldStrength 3 
PulseSequ

[Freesurfer] Fwd: mri_glmfit-sim --surf question

2018-03-02 Thread Adam Mecca
Hello FreeSurfer Developers,

I have run a glm on the left hemisphere to compare cortical thickness
between 2 groups. After, I did a cluster-wise correction with permutation
testing using this command

mri_glmfit-sim --glmdir lh.sv2a_group.glmdir.10 --perm 1000 2 abs

It completes without error, but I have a question about the log file and
--surf argument. My concern if about this part of the log file where it
shows "--surf fsaverage lh white" (see section from log file and complete
log file attached). White is the default I based on the help file for
mri_glmfit. Should I be running with --surf fsaverage lh pial?

Does this imply that the glm is performed on the white matter surface. I am
then visualizing on the inflated pial surface so does this cause a problem?

--
1/1 Fri Mar  2 03:23:25 EST 2018
mri_glmfit --C 
lh.sv2a_group.glmdir.10/tmp.mri_glmfit-sim-13158/sv2a_thickness_group.mtx
--sim perm 1000 2 lh.sv2a_group.glmdir.10/csd/perm.th20.abs.j001 --sim-sign
abs --fwhm 0 --fsgd lh.sv2a_group.glmdir.10/y.fsgd dods --y
lh.sv2a.group.thickness.10.mgh --mask lh.sv2a_group.glmdir.10/mask.mgh
--surf fsaverage lh white
simbase lh.sv2a_group.glmdir.10/csd/perm.th20.abs.j001
FWHM = 0.00
gdfRead(): reading lh.sv2a_group.glmdir.10/y.fsgd
INFO: gd2mtx_method is dods
Reading source surface /home1/am2359/fs6_data/fpeb_
app_fs/fsaverage/surf/lh.white
---


Thank you,
Adam

cd /home1/am2359/fs6_data/fpeb_app_fs
/home1/am2359/freesurfer_6/bin/mri_glmfit-sim
--glmdir lh.sv2a_group.glmdir.10 --perm 1000 2 abs

$Id: mri_glmfit-sim,v 1.60.2.4 2016/11/17 18:01:28 zkaufman Exp $
Fri Mar  2 03:23:25 EST 2018
Linux tauruspet.med.yale.edu 2.6.32-696.el6.x86_64 #1 SMP Tue Mar 21 19:29:05 UTC 2017 x86_64 x86_64 x86_64 GNU/Linux
am2359
setenv SUBJECTS_DIR /home1/am2359/fs6_data/fpeb_app_fs
FREESURFER_HOME /home1/am2359/freesurfer_6

Original mri_glmfit command line:
cmdline mri_glmfit.bin --y lh.sv2a.group.thickness.10.mgh --fsgd dx_sv2a.fsgd --C sv2a_thickness_group.mtx --surf fsaverage lh --cortex --glmdir lh.sv2a_group.glmdir.10

DoSim = 1
UseCache = 0
DoPoll = 0
DoPBSubmit = 0
DoBackground = 0
DiagCluster = 0
gd2mtx = dods
fwhm = 0
nSimPerJob = 1000
1/1 Fri Mar  2 03:23:25 EST 2018
mri_glmfit --C lh.sv2a_group.glmdir.10/tmp.mri_glmfit-sim-13158/sv2a_thickness_group.mtx --sim perm 1000 2 lh.sv2a_group.glmdir.10/csd/perm.th20.abs.j001 --sim-sign abs --fwhm 0 --fsgd lh.sv2a_group.glmdir.10/y.fsgd dods --y lh.sv2a.group.thickness.10.mgh --mask lh.sv2a_group.glmdir.10/mask.mgh --surf fsaverage lh white
simbase lh.sv2a_group.glmdir.10/csd/perm.th20.abs.j001
FWHM = 0.00
gdfRead(): reading lh.sv2a_group.glmdir.10/y.fsgd
INFO: gd2mtx_method is dods
Reading source surface /home1/am2359/fs6_data/fpeb_app_fs/fsaverage/surf/lh.white
Number of vertices 163842
Number of faces327680
Total area 65416.984375
AvgVtxArea   0.399269
AvgVtxDist   0.721953
StdVtxDist   0.195470

$Id: mri_glmfit.c,v 1.241.2.4 2016/12/08 22:02:40 zkaufman Exp $
cwd /home1/am2359/fs6_data/fpeb_app_fs
cmdline mri_glmfit.bin --C lh.sv2a_group.glmdir.10/tmp.mri_glmfit-sim-13158/sv2a_thickness_group.mtx --sim perm 1000 2 lh.sv2a_group.glmdir.10/csd/perm.th20.abs.j001 --sim-sign abs --fwhm 0 --fsgd lh.sv2a_group.glmdir.10/y.fsgd dods --y lh.sv2a.group.thickness.10.mgh --mask lh.sv2a_group.glmdir.10/mask.mgh --surf fsaverage lh white 
sysname  Linux
hostname tauruspet.med.yale.edu
machine  x86_64
user am2359
FixVertexAreaFlag = 1
UseMaskWithSmoothing 1
OneSampleGroupMean 0
y/home1/am2359/fs6_data/fpeb_app_fs/lh.sv2a.group.thickness.10.mgh
logyflag 0
usedti  0
FSGD lh.sv2a_group.glmdir.10/y.fsgd
mask lh.sv2a_group.glmdir.10/mask.mgh
maskinv 0
glmdir (null)
IllCondOK 0
ReScaleX 1
DoFFx 0
Loading y from /home1/am2359/fs6_data/fpeb_app_fs/lh.sv2a.group.thickness.10.mgh
   ... done reading.
INFO: gd2mtx_method is dods
Computing normalized matrix
Normalized matrix condition is 1
Matrix condition is 1.1
Found 149953 voxels in mask
Reshaping mriglm->mask...
search space = 74612.064358
DOF = 19
thresh = 2, threshadj = 1.69897 


Starting simulation sim over 1000 trials
mri_glmfit simulation done 20.274


Fri Mar  2 03:43:45 EST 2018
mri_surfcluster --in lh.sv2a_group.glmdir.10/sv2a_thickness_group/sig.mgh --mask lh.sv2a_group.glmdir.10/mask.mgh --cwsig lh.sv2a_group.glmdir.10/sv2a_thickness_group/perm.th20.abs.sig.cluster.mgh --sum lh.sv2a_group.glmdir.10/sv2a_thickness_group/perm.th20.abs.sig.cluster.summary --ocn lh.sv2a_group.glmdir.10/sv2a_thickness_group/perm.th20.abs.sig.ocn.mgh --annot aparc --cwpvalthresh .05 --o lh.sv2a_group.glmdir.10/sv2a_thickness_group/perm.th20.abs.sig.masked.mgh --no-fixmni --csd lh.sv2a_group.glmdir.10/csd/perm.th20.abs.j001-sv2a_thickness_group.csd --csdpdf lh.sv2a_group.glmdir.10/sv2a_thickness_group/perm.th20.abs.pdf.dat --vwsig lh.sv2a_group.glmdir.10