[Freesurfer] FMRI Asymmetry Analyses

2011-08-17 Thread Andy Mayer
Hello-



 Trying this post again. I would like to directly compare
asymmetries in FMRI activation in surface space based on the Greve et al
poster presented at HBM this year.  We would like to register each subject’s
T1 data to the contralateral hemisphere of fsaverage and made templates of
the contra (?h.con.sphere.reg ) and ipsilateral (?h.sphere.reg )
registrations. Is the following correct for the cross hemisphere
registration? Thanks


mris_register -reverse -curv surf/rh.sphere
{$FREESURFER_HOME}/average/lh.average.curvature.filled.buckner40.tif
surf/rh.CON.sphere.reg
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Re: [Freesurfer] FMRI Asymmetry Analyses

2011-08-17 Thread Douglas N Greve
I don't have any docs set up and ready to use, but here are some 
instructions that should get you started.
doug


---
Download these files
ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/surfreg
ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/xhemireg
ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/fsaverage_sym.tar.gz

# Copy surfreg and xhemireg into $FREESURFER_HOME/bin
# Untar fsaverage_sym.tar.gz into your $SUBJECTS_DIR
cd $SUBJECTS_DIR
tar xvfz fsaverage_sym.tar.gz

-
To apply an existing atlas (eg, fsaverage_sym) to an anatomical analysis

# Reg to atlas (1-2 hours per subject)
# Creates $subject/xhemi
# Creates lh.fsaverage_sym.sphere.reg in $subject and $subject/xhemi
foreach subject (subjectlist)
  surfreg --s $subject --t fsaverage_sym --lh
  surfreg --s $subject --t fsaverage_sym --lh --xhemi
end

# Create a stack of subjects
mris_preproc --target fsaverage_sym --hemi lh
  --xhemi --paired-diff \
  --srcsurfreg fsaverage_sym.sphere.reg \
  --meas thickness \
  --out lh.lh-rh.thickness.sm00.mgh \
  --s subj1 --s subj2 ...

# Smooth
mris_fwhm --s fsaverage_sym --hemi lh --cortex --smooth-only --fwhm 5\
 --i lh.lh-rh.thickness.sm00.mgh --o lh.lh-rh.thickness.sm05.mgh

# Test
mri_glmfit --y lh.lh-rh.thickness.sm05.mgh --glmdir 
glm.lh.lh-rh.thickness.sm05 \
 --osgm --surf fsaverage_sym lh

# View
tksurfer fsaverage_sym lh inflated -aparc -overlay 
glm.lh.lh-rh.thickness.sm05/osgm/sig.mgh

# Correct for MC (need new version of mri_glmfit-sim)
mri_glmfit-sim --glmdir glm.lh.lh-rh.thickness.sm05 \
   --cwpvalthresh .5 --cache 2 abs \
   --subject-override fsaverage

-

# To apply an existing atlas to an arbitray volume data set:

bbregister --s subject --reg register.dat ...
mri_vol2surf --reg register.dat --mov data.nii.gz --hemi lh --o data.lh.nii
mri_vol2surf --reg register.dat --mov data.nii.gz --hemi rh --o data.rh.nii

# Map lh data to fsaverage_sym
mri_surf2surf --srcsubject subject --srcsurfreg fsaverage_sym.sphere.reg \
  --trgsubject fsaverage_sym --trgsurfreg sphere.reg --hemi lh --sval 
data.lh.nii \
  --tval data.lh.fsaverage_sym.nii

# Map rh data to fsaverage_sym. Note: (1) "subject" is subject/xhemi
# and (2) The hemi (--hemi lh) is still lh not rh.
mri_surf2surf --srcsubject subject/xhemi --srcsurfreg 
fsaverage_sym.sphere.reg \
  --trgsubject fsaverage_sym --trgsurfreg sphere.reg --hemi lh --sval 
data.rh.nii \
  --tval data.rh.fsaverage_sym.nii

data.lh.fsaverage_sym.nii and data.rh.fsaverage_sym.nii are now in
voxel-for-voxel registration.


Andy Mayer wrote:
>
> Hello-
>
>  
>
>  Trying this post again. I would like to directly compare 
> asymmetries in FMRI activation in surface space based on the Greve et 
> al poster presented at HBM this year.  We would like to register each 
> subject’s T1 data to the contralateral hemisphere of fsaverage and 
> made templates of the contra (?h.con.sphere.reg ) and ipsilateral 
> (?h.sphere.reg ) registrations. Is the following correct for the cross 
> hemisphere registration? Thanks
>
>  
>
> mris_register -reverse -curv surf/rh.sphere 
> {$FREESURFER_HOME}/average/lh.average.curvature.filled.buckner40.tif 
> surf/rh.CON.sphere.reg
>  
>  
> 
>
> ___
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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