Re: [Freesurfer] Query about the calculation of surface area

2015-10-07 Thread Bruce Fischl

Hi Feng

thickness has a biological meaning as a point measure, but area does not. 
The area of any given triangle doesn't carry any biologically relevant 
information that I can think of, which is why we don't quantify the 
statistics of the area of individual triangles


cheers
Bruce


On Wed, 7 Oct 2015, chenhf_uestc wrote:


I thought that we calculate the Surface area, MeanCurv, GausCurv, FoldInd
and CurvInd in each vertex, and thus we can obtain the whole map on the
surface.
Subsequently, using the predefined atlas, we can further obtain the mean and
std value in each brain region (because each vertex has a value). It looks
like you do not calculate surface area and other measures in the
aforementioned way, right?
 
From your words, it may be that the surface area is the summation of each
vertex's area in each region, right? In contrast, for thickness, you compute
the mean thickness across all the vertics. And of coz, I can compute the
total thickness in each region like the area (summation of each vertex's
thickness in each region), right?
 
Best,
Feng


  发件人:Bruce Fischl 
发送时间:2015-10-07 22:32
主题:Re: [Freesurfer] Query about the calculation of surface area
收件人:"Freesurfer support list"
抄送:
 
Hi Feng 
 
they are slightly different measures so which one you use really depends  
on your biological hypothesis. 
 
For thickness there are multiple measures within each ROI but only one area
  
(that of the whole ROI), so mean and std doesn't make sense. 
 
cheers 
Bruce 
 
On Wed, 7 Oct 2015, chenhf_uestc wrote: 
 
> Thanks a lot, Bruce 
>   
> If I want to compare the surface area between the patients and healthy 
> control groups, which area file should I use? The area or the area.pial?

?? ?Or 

> I should compare both of them? If I should use both, is there any 
> possibility that I would obtain different results from area and area.pial
? I 
> mean, in this case, a brain region has significantly different area but s
ame 
> (not significant) area.pial. How can I explain them in my research paper?
 
>   
> BTW, just out of curiosity, in the stats file such as lh.aparc.stats, why
 
> just thickness has the mean and std value, but other measures do not have
 
> the std value?  
> SurfArea GrayVol ThickAvg ThickStd MeanCurv GausCurv FoldInd CurvInd 
>   
> Best, 
> Feng 
>  
> _________
___ 
>   发件人:Bruce Fischl  
> 发送时间:2015-10-06 20:45 
> 主题:Re: [Freesurfer] Query about the calculation of surface area 
> 收件人:"Freesurfer support list" 
> 抄送: 
>   
> yes, that is correct  
> Bruce  
>   
>   
> On Tue, 6 Oct 2015, chenhf_uestc wrote:  
>   
> > Thanks, Bruce   So, in the stats folder of each subject, the   
> > lh.aparc.a2009s.stats file provides surfarea of each region. This value
  
?? ?> is the area for the white surface, right? 
> > Is the area of each vertex obtained by the average the area of triangle
s 
?? ?su   
> > rrounding the vertex?Best, Feng  
> >   
> > ___________________
__ 
> ___  
> >   发件人:Bruce Fischl   
> > 发送时间:2015-10-06 20:25  
> > 主题:Re: [Freesurfer] Query about the calculation of surface area  
> > 收件人:"Freesurfer support list"  
> > 抄送:  
> >
> > Hi Feng   
> >
> > we compute the surface area of each surface and store it separately. Th
e 
?? ?   
> > ?h.area files are for the white surface and the ?h.area.pial for the pi
al 
>
> >
> > cheers   
> > Bruce   
> > On
> > Tue, 6 Oct 2015, chenhf_uestc wrote:   
> >
> > > Dear Freesurfer experts,   
> > > 
> > > I have a question about the calculation of surface area. The cortical
  
?? ?> > thickness is the distance between the pial and white matter. But, w
hat 
?? ?ab  
> > out   
> > > the surface area? Calculation based on pial or white matter? Or avera
ge 
>  t  
> > he   
> > > area of both of them.   
> > > 
> > > Is the area of each vertex obtained by the average the area of triang
le 
> s  
> ?? ?> surrounding the vertex?   
> > > In addition, where can I find the definition of meancurv, gauscurv, f
ol 
> di  
> > nd,   
> > > curvind? I do not find it in the fswiki.   
> > > 
> > > Best,   
> > > Feng   
> > > 
> > >
> > >   
> > ___   
> > Freesurfer mailing list   
> > Freesurfer@nmr.mgh.harvard.edu   
> > https://mail.nmr.mgh.harvard.edu/ma

Re: [Freesurfer] Query about the calculation of surface area

2015-10-07 Thread chenhf_uestc
I thought that we calculate the Surface area, MeanCurv, GausCurv, FoldInd and 
CurvInd in each vertex, and thus we can obtain the whole map on the surface. 
Subsequently, using the predefined atlas, we can further obtain the mean and 
std value in each brain region (because each vertex has a value). It looks like 
you do not calculate surface area and other measures in the aforementioned way, 
right?

From your words, it may be that the surface area is the summation of each 
vertex's area in each region, right? In contrast, for thickness, you compute 
the mean thickness across all the vertics. And of coz, I can compute the total 
thickness in each region like the area (summation of each vertex's thickness in 
each region), right?

Best,
Feng



发件人:Bruce Fischl 
发送时间:2015-10-07 22:32
主题:Re: [Freesurfer] Query about the calculation of surface area
收件人:"Freesurfer support list"
抄送:

Hi Feng 

they are slightly different measures so which one you use really depends  
on your biological hypothesis. 

For thickness there are multiple measures within each ROI but only one area  
(that of the whole ROI), so mean and std doesn't make sense. 

cheers 
Bruce 

On Wed, 7 Oct 2015, chenhf_uestc wrote: 

> Thanks a lot, Bruce 
>   
> If I want to compare the surface area between the patients and healthy 
> control groups, which area file should I use? The area or the area.pial? Or 
> I should compare both of them? If I should use both, is there any 
> possibility that I would obtain different results from area and area.pial? I 
> mean, in this case, a brain region has significantly different area but same 
> (not significant) area.pial. How can I explain them in my research paper? 
>   
> BTW, just out of curiosity, in the stats file such as lh.aparc.stats, why 
> just thickness has the mean and std value, but other measures do not have 
> the std value?  
> SurfArea GrayVol ThickAvg ThickStd MeanCurv GausCurv FoldInd CurvInd 
>   
> Best, 
> Feng 
>  
> ________ 
>       发件人:Bruce Fischl  
> 发送时间:2015-10-06 20:45 
> 主题:Re: [Freesurfer] Query about the calculation of surface area 
> 收件人:"Freesurfer support list" 
> 抄送: 
>   
> yes, that is correct  
> Bruce  
>   
>   
> On Tue, 6 Oct 2015, chenhf_uestc wrote:  
>   
> > Thanks, Bruce   So, in the stats folder of each subject, the   
> > lh.aparc.a2009s.stats file provides surfarea of each region. This value  
?? ?> is the area for the white surface, right? 
> > Is the area of each vertex obtained by the average the area of triangles 
?? ?su   
> > rrounding the vertex?Best, Feng  
> >   
> > _____________________ 
> ___  
> >   发件人:Bruce Fischl   
> > 发送时间:2015-10-06 20:25  
> > 主题:Re: [Freesurfer] Query about the calculation of surface area  
> > 收件人:"Freesurfer support list"  
> > 抄送:  
> >
> > Hi Feng   
> >
> > we compute the surface area of each surface and store it separately. The 
?? ?   
> > ?h.area files are for the white surface and the ?h.area.pial for the pial 
>
> >
> > cheers   
> > Bruce   
> > On
> > Tue, 6 Oct 2015, chenhf_uestc wrote:   
> >
> > > Dear Freesurfer experts,   
> > > 
> > > I have a question about the calculation of surface area. The cortical  
?? ?> > thickness is the distance between the pial and white matter. But, what 
?? ?ab  
> > out   
> > > the surface area? Calculation based on pial or white matter? Or average 
>  t  
> > he   
> > > area of both of them.   
> > > 
> > > Is the area of each vertex obtained by the average the area of triangle 
> s  
> ?? ?> surrounding the vertex?   
> > > In addition, where can I find the definition of meancurv, gauscurv, fol 
> di  
> > nd,   
> > > curvind? I do not find it in the fswiki.   
> > > 
> > > Best,   
> > > Feng   
> > > 
> > >
> > >   
> > ___   
> > Freesurfer mailing list   
> > Freesurfer@nmr.mgh.harvard.edu   
> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer   
> >
> >
> > The information in this e-mail is intended only for the person to whom it 
>  i  
> > s   
> > addressed. If you believe this e-mail was sent to you in error and the e- 
> ma  
> > il   
> > contains patient information, please contact the Partners Compliance Help 
> Li  
> > ne at   
> > http://www.partners.org/complianceline . If the

Re: [Freesurfer] Query about the calculation of surface area

2015-10-07 Thread Bruce Fischl

Hi Feng

they are slightly different measures so which one you use really depends 
on your biological hypothesis.


For thickness there are multiple measures within each ROI but only one area 
(that of the whole ROI), so mean and std doesn't make sense.


cheers
Bruce

On Wed, 7 Oct 2015, chenhf_uestc wrote:


Thanks a lot, Bruce
 
If I want to compare the surface area between the patients and healthy
control groups, which area file should I use? The area or the area.pial? Or
I should compare both of them? If I should use both, is there any
possibility that I would obtain different results from area and area.pial? I
mean, in this case, a brain region has significantly different area but same
(not significant) area.pial. How can I explain them in my research paper?
 
BTW, just out of curiosity, in the stats file such as lh.aparc.stats, why
just thickness has the mean and std value, but other measures do not have
the std value? 
SurfArea GrayVol ThickAvg ThickStd MeanCurv GausCurv FoldInd CurvInd
 
Best,
Feng


  发件人:Bruce Fischl 
发送时间:2015-10-06 20:45
主题:Re: [Freesurfer] Query about the calculation of surface area
收件人:"Freesurfer support list"
抄送:
 
yes, that is correct 
Bruce 
 
 
On Tue, 6 Oct 2015, chenhf_uestc wrote: 
 
> Thanks, Bruce   So, in the stats folder of each subject, the  
> lh.aparc.a2009s.stats file provides surfarea of each region. This value 

?? ?> is the area for the white surface, right?

> Is the area of each vertex obtained by the average the area of triangles

?? ?su  

> rrounding the vertex?Best, Feng 
>  
> _
___ 
>   发件人:Bruce Fischl  
> 发送时间:2015-10-06 20:25 
> 主题:Re: [Freesurfer] Query about the calculation of surface area 
> 收件人:"Freesurfer support list" 
> 抄送: 
>   
> Hi Feng  
>   
> we compute the surface area of each surface and store it separately. The

?? ?  

> ?h.area files are for the white surface and the ?h.area.pial for the pial
  
>   
> cheers  
> Bruce  
> On   
> Tue, 6 Oct 2015, chenhf_uestc wrote:  
>   
> > Dear Freesurfer experts,  
> >
> > I have a question about the calculation of surface area. The cortical 

?? ?> > thickness is the distance between the pial and white matter. But, what
?? ?ab 

> out  
> > the surface area? Calculation based on pial or white matter? Or average
 t 
> he  
> > area of both of them.  
> >
> > Is the area of each vertex obtained by the average the area of triangle
s 
?? ?> surrounding the vertex?  
> > In addition, where can I find the definition of meancurv, gauscurv, fol
di 
> nd,  
> > curvind? I do not find it in the fswiki.  
> >
> > Best,  
> > Feng  
> >
> >   
> >  
> ___  
> Freesurfer mailing list  
> Freesurfer@nmr.mgh.harvard.edu  
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer  
>   
>   
> The information in this e-mail is intended only for the person to whom it
 i 
> s  
> addressed. If you believe this e-mail was sent to you in error and the e-
ma 
> il  
> contains patient information, please contact the Partners Compliance Help
Li 
> ne at  
> http://www.partners.org/complianceline . If the e-mail was sent to you in
 e 
> rror  
> but does not contain patient information, please contact the sender and p
ro 
> perly  
> dispose of the e-mail.  
>   
>  
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Re: [Freesurfer] Query about the calculation of surface area

2015-10-06 Thread chenhf_uestc
Thanks a lot, Bruce

If I want to compare the surface area between the patients and healthy control 
groups, which area file should I use? The area or the area.pial? Or I should 
compare both of them? If I should use both, is there any possibility that I 
would obtain different results from area and area.pial? I mean, in this case, a 
brain region has significantly different area but same (not significant) 
area.pial. How can I explain them in my research paper?

BTW, just out of curiosity, in the stats file such as lh.aparc.stats, why just 
thickness has the mean and std value, but other measures do not have the std 
value? 
SurfArea GrayVol ThickAvg ThickStd MeanCurv GausCurv FoldInd CurvInd

Best,
Feng



发件人:Bruce Fischl 
发送时间:2015-10-06 20:45
主题:Re: [Freesurfer] Query about the calculation of surface area
收件人:"Freesurfer support list"
抄送:

yes, that is correct 
Bruce 


On Tue, 6 Oct 2015, chenhf_uestc wrote: 

> Thanks, Bruce   So, in the stats folder of each subject, the  
> lh.aparc.a2009s.stats file provides surfarea of each region. This value  
> is the area for the white surface, right?
> Is the area of each vertex obtained by the average the area of triangles su  
> rrounding the vertex?Best, Feng 
>  
>  
>   发件人:Bruce Fischl  
> 发送时间:2015-10-06 20:25 
> 主题:Re: [Freesurfer] Query about the calculation of surface area 
> 收件人:"Freesurfer support list" 
> 抄送: 
>   
> Hi Feng  
>   
> we compute the surface area of each surface and store it separately. The   
> ?h.area files are for the white surface and the ?h.area.pial for the pial  
>   
> cheers  
> Bruce  
> On   
> Tue, 6 Oct 2015, chenhf_uestc wrote:  
>   
> > Dear Freesurfer experts,  
> >
> > I have a question about the calculation of surface area. The cortical  
> > thickness is the distance between the pial and white matter. But, what ab 
> out  
> > the surface area? Calculation based on pial or white matter? Or average t 
> he  
> > area of both of them.  
> >
> > Is the area of each vertex obtained by the average the area of triangles 
?? ?> surrounding the vertex?  
> > In addition, where can I find the definition of meancurv, gauscurv, foldi 
> nd,  
> > curvind? I do not find it in the fswiki.  
> >
> > Best,  
> > Feng  
> >
> >   
> >  
> ___  
> Freesurfer mailing list  
> Freesurfer@nmr.mgh.harvard.edu  
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer  
>   
>   
> The information in this e-mail is intended only for the person to whom it i 
> s  
> addressed. If you believe this e-mail was sent to you in error and the e-ma 
> il  
> contains patient information, please contact the Partners Compliance HelpLi 
> ne at  
> http://www.partners.org/complianceline . If the e-mail was sent to you in e 
> rror  
> but does not contain patient information, please contact the sender and pro 
> perly  
> dispose of the e-mail.  
>   
>  
>  
> 
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Re: [Freesurfer] Query about the calculation of surface area

2015-10-06 Thread Bruce Fischl

yes, that is correct
Bruce


On Tue, 6 Oct 2015, chenhf_uestc wrote:

Thanks, Bruce   So, in the stats folder of each subject, the 
lh.aparc.a2009s.stats file provides surfarea of each region. This value 
is the area for the white surface, right?   
Is the area of each vertex obtained by the average the area of triangles su 
rrounding the vertex?    Best, Feng



  发件人:Bruce Fischl 
发送时间:2015-10-06 20:25
主题:Re: [Freesurfer] Query about the calculation of surface area
收件人:"Freesurfer support list"
抄送:
 
Hi Feng 
 
we compute the surface area of each surface and store it separately. The  
?h.area files are for the white surface and the ?h.area.pial for the pial 
 
cheers 
Bruce 
On  
Tue, 6 Oct 2015, chenhf_uestc wrote: 
 
> Dear Freesurfer experts, 
>   
> I have a question about the calculation of surface area. The cortical 
> thickness is the distance between the pial and white matter. But, what ab
out 
> the surface area? Calculation based on pial or white matter? Or average t
he 
> area of both of them. 
>   
> Is the area of each vertex obtained by the average the area of triangles

?? ?> surrounding the vertex? 

> In addition, where can I find the definition of meancurv, gauscurv, foldi
nd, 
> curvind? I do not find it in the fswiki. 
>   
> Best, 
> Feng 
>   
>  
> 
___ 
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Re: [Freesurfer] Query about the calculation of surface area

2015-10-06 Thread chenhf_uestc
Thanks, Bruce

So, in the stats folder of each subject, the lh.aparc.a2009s.stats file 
provides surfarea of each region. This value is the area for the white surface, 
right?

Is the area of each vertex obtained by the average the area of triangles 
surrounding the vertex? 

Best,
Feng



发件人:Bruce Fischl 
发送时间:2015-10-06 20:25
主题:Re: [Freesurfer] Query about the calculation of surface area
收件人:"Freesurfer support list"
抄送:

Hi Feng 

we compute the surface area of each surface and store it separately. The  
?h.area files are for the white surface and the ?h.area.pial for the pial 

cheers 
Bruce 
On  
Tue, 6 Oct 2015, chenhf_uestc wrote: 

> Dear Freesurfer experts, 
>   
> I have a question about the calculation of surface area. The cortical 
> thickness is the distance between the pial and white matter. But, what about 
> the surface area? Calculation based on pial or white matter? Or average the 
> area of both of them. 
>   
> Is the area of each vertex obtained by the average the area of triangles 
> surrounding the vertex? 
> In addition, where can I find the definition of meancurv, gauscurv, foldind, 
> curvind? I do not find it in the fswiki. 
>   
> Best, 
> Feng 
>   
>  
> 
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Re: [Freesurfer] Query about the calculation of surface area

2015-10-06 Thread Bruce Fischl

Hi Feng

we compute the surface area of each surface and store it separately. The 
?h.area files are for the white surface and the ?h.area.pial for the pial


cheers
Bruce
On 
Tue, 6 Oct 2015, chenhf_uestc wrote:



Dear Freesurfer experts,
 
I have a question about the calculation of surface area. The cortical
thickness is the distance between the pial and white matter. But, what about
the surface area? Calculation based on pial or white matter? Or average the
area of both of them.
 
Is the area of each vertex obtained by the average the area of triangles
surrounding the vertex?
In addition, where can I find the definition of meancurv, gauscurv, foldind,
curvind? I do not find it in the fswiki.
 
Best,
Feng
 

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[Freesurfer] Query about the calculation of surface area

2015-10-06 Thread chenhf_uestc
Dear Freesurfer experts,

I have a question about the calculation of surface area. The cortical thickness 
is the distance between the pial and white matter. But, what about the surface 
area? Calculation based on pial or white matter? Or average the area of both of 
them. 

Is the area of each vertex obtained by the average the area of triangles 
surrounding the vertex? 
In addition, where can I find the definition of meancurv, gauscurv, foldind, 
curvind? I do not find it in the fswiki.

Best,
Feng___
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Freesurfer@nmr.mgh.harvard.edu
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The information in this e-mail is intended only for the person to whom it is
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