[Freesurfer] Question about design matrix for surface group analysis
External Email - Use Caution Dear freesurfer users, I have a question about the design matrix.We want to analyse the relationship between the cortical thickness and the neuropsychological test. We have two groups:TLE and extralTLE,one discrete variable:gender,and two continuous variable: neuropsychological test and age. we make the FSGD files like this:Title OSGM Class MaleTLE Class MaleextraTLE Class FemaleTLE Class FemaleexatrTLE Variables Age Neuropsychology Input subject1 MaleTLE 30 5 Input subject2 MaleextraTLE 40 6 Input subject3 FemaleTLE 50 8 Input subject4 FemaleLextraTLE 60 7 Is it right? And we want to analyze the relationship between the cortical thickness and the neuropsychology regressing out the effects of gender and age, how to make the design matrix? Look forward to your reply. Sincerely, Kan Deng___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Re: [Freesurfer] Question about design matrix for surface group analysis
yes, that looks right to me. On 11/8/19 1:28 AM, 邓刊 wrote: > > External Email - Use Caution > > Dear freesurfer users, > I have a question about the design matrix.We want to analyse the > relationship between the cortical thickness and the neuropsychological > test. We have two groups:TLE and extralTLE,one discrete > variable:gender,and two continuous variable: neuropsychological test > and age. > we make the FSGD files like this: > Title OSGM > > Class MaleTLE > > Class MaleextraTLE > > Class FemaleTLE > > Class FemaleexatrTLE > > Variables Age Neuropsychology > > Input subject1 MaleTLE 30 5 > > Input subject2 MaleextraTLE 40 6 > > Input subject3 FemaleTLE 50 8 > > Input subject4 FemaleLextraTLE 60 7 > > Is it right? And we want to analyze the relationship between the > cortical thickness and the neuropsychology regressing out the effects > of gender and age, how to make the design matrix? > Look forward to your reply. > Sincerely, > Kan Deng > > > > > ___ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Re: [Freesurfer] Question about design matrix for surface group analysis
External Email - Use Caution Dear freesurfer experts,we want to analyze the relationship between the cortical thickness and the neuropsychology regressing out the effects of gender and age, but I don't know how to make the design matrix? Is it [0.5 -0.5 0.5 -0.5 0 0 0 0 1 -1 1 -1 ] ? Best wishes, Kan At 2019-11-12 01:18:10, "Greve, Douglas N.,Ph.D." wrote: >yes, that looks right to me. > >On 11/8/19 1:28 AM, 邓刊 wrote: >> >> External Email - Use Caution >> Dear freesurfer users, >> Dear freesurfer users, >> I have a question about the design matrix.We want to analyse the >> relationship between the cortical thickness and the neuropsychological >> test. We have two groups:TLE and extralTLE,one discrete >> variable:gender,and two continuous variable: neuropsychological test >> and age. >> we make the FSGD files like this: >> Title OSGM >> >>Class MaleTLE >> >>Class MaleextraTLE >> >>Class FemaleTLE >> >>Class FemaleexatrTLE >> >>Variables Age Neuropsychology >> >>Input subject1 MaleTLE 30 5 >> >>Input subject2 MaleextraTLE 40 6 >> >>Input subject3 FemaleTLE 50 8 >> >>Input subject4 FemaleLextraTLE 60 7 >> >> Is it right? And we want to analyze the relationship between the >> cortical thickness and the neuropsychology regressing out the effects >> of gender and age, how to make the design matrix? >> Look forward to your reply. >> Sincerely, >> Kan Deng >> >> >> >> >> ___ >> Freesurfer mailing list >> Freesurfer@nmr.mgh.harvard.edu >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > >___ >Freesurfer mailing list >Freesurfer@nmr.mgh.harvard.edu >https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Re: [Freesurfer] Question about design matrix for surface group analysis
You have 4 classes and 2 variables, so you will have 4*(2+1)=12 regressors: MTLE MExTLE FTLE FExTLE MTLEage MExTLEage FTLEage FExTLEage MTLEneuro MExTLEneuro FTLEneuro FExTLEneuro You are interested in the diff between TLE and xTLE on the neuro score regressing out the effects of gender and age (right?), so this would be your contrast matrix [0 0 0 0 0 0 0 0 0.5 -0.5 0.5 -0.5] On 11/14/19 1:51 AM, 邓刊 wrote: > > External Email - Use Caution > > Dear freesurfer experts, > we want to analyze the relationship between the cortical thickness and > the neuropsychology regressing out the effects of gender and age, but > I don't know how to make the design matrix? Is it [0.5 -0.5 0.5 -0.5 0 > 0 0 0 1 -1 1 -1 ] ? > > Best wishes, > Kan > > > > At 2019-11-12 01:18:10, "Greve, Douglas N.,Ph.D." > wrote: > >yes, that looks right to me. > > > >On 11/8/19 1:28 AM, 邓刊 wrote: > >> > >> External Email - Use Caution > >> Dear freesurfer users, > > >> Dear freesurfer users, > >> I have a question about the design matrix.We want to analyse the > >> relationship between the cortical thickness and the neuropsychological > >> test. We have two groups:TLE and extralTLE,one discrete > >> variable:gender,and two continuous variable: neuropsychological test > >> and age. > >> we make the FSGD files like this: > >> Title OSGM > >> > >> Class MaleTLE > >> > >> Class MaleextraTLE > >> > >> Class FemaleTLE > >> > >> Class FemaleexatrTLE > >> > >> Variables Age Neuropsychology > >> > >> Input subject1 MaleTLE 30 5 > >> > >> Input subject2 MaleextraTLE 40 6 > >> > >> Input subject3 FemaleTLE 50 8 > >> > >> Input subject4 FemaleLextraTLE 60 7 > >> > >> Is it right? And we want to analyze the relationship between the > >> cortical thickness and the neuropsychology regressing out the effects > >> of gender and age, how to make the design matrix? > >> Look forward to your reply. > >> Sincerely, > >> Kan Deng > >> > >> > >> > >> > >> ___ > >> Freesurfer mailing list > >> Freesurfer@nmr.mgh.harvard.edu > >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > > > >___ > >Freesurfer mailing list > >Freesurfer@nmr.mgh.harvard.edu > >https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > > > ___ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
