Re: [Freesurfer] Question about running recon-all with deface

2015-12-15 Thread Mishra, Virendra
Hi Bruce,

When the thickness/volume measure was compared between the results obtained 
with recon-all with and without defaced T1 as input to recon-all, we obtained 
20% errors (between them)

Example: 100*(Thalamus_left_volume_with_defaced_T1_to_recon-all MINUS  
Thalamus_left_volume_without_deface_T1_to_recon_all)/( 
thalamus_left_volume_without_deface_T1_to_recon_all)

We think, we would rather run recon-all with the face but use -deface flag 
during recon-all.

Thanks

Regards

Virendra

-Original Message-
From: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Bruce Fischl
Sent: Monday, December 14, 2015 10:05 AM
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] Question about running recon-all with deface

Hi Virenda

can you say what you mean by 20% errors? Compared to what? Note for example 
that a 20% variation in the thickness at one spot would mean a change of 0.4mm 
(for 2mm thick cortex). Seeing this type of variation point-wise somewhere in 
the brain isn't terribly surprising, although I wish it were less. Defacing 
will definitely change things (e.g. skull stripping, bias estimation and 
removal, etc...)

cheers
Bruce
On Mon, 14 Dec 2015, Mishra,
Virendra wrote:

> 
> Hi,
> 
>  
> 
> I will appreciate if somebody could reply to my message that was posted 
> earlier. I copy-paste the message here again.
> 
>  
> 
> We are currently in the process of analyzing some data that was 
> defaced using mri_deface command of freesurfer. This defaced data was 
> then used as an input to recon-all and the volume and thickness was 
> computed. These results were then compared against the same subject’s 
> recon-all with the face but with and without the deface flag within 
> recon-all. All of the steps were done on version 5.3.0 on CentOS. We have got 
> some differences and we are unable to explain why. Some of the regions have 
> error greater than 20% when the input was a defaced brain. We would 
> appreciate if you could advise as to how to approach to the same results as 
> we were running the data with the face .
> 
>  
> 
> To summarize: (The commands are not precise below but we ensured the 
> commands are run correctly per the command help)
> 
> 1)  Step 1: mri_deface -i original_T1 -o deface_T1
> 
> 2)  Step 2: recon-all -i deface_T1
> 
> 3)  Step 3: recon-all –i original_T1 –deface
> 
> 4)  Step 4: recon-all –i original_T1
> 
> 5)  The results from Step 3 is exactly equal to Step 4
> 
> 6)  The results from Step 2 and Step3/4 have errors >20% in certain 
> regions.
> 
> 7)  Step 1-4 are done with version 5.3.0
> 
>  
> 
> Any response will be greatly appreciated.
> 
>  
> 
>  
> 
> Thanks
> 
>  
> 
> Regards
> 
>  
> 
> Virendra
> 
> ===
> 
> Please consider the environment before printing this e-mail
> 
> Cleveland Clinic is ranked as one of the top hospitals in America by 
> U.S.News & World Report (2015). Visit us online at 
> http://www.clevelandclinic.org for a complete listing of our services, 
> staff and locations. Confidentiality Note: This message is intended 
> for use only by the individual or entity to which it is addressed and 
> may contain information that is privileged, confidential, and exempt 
> from disclosure under applicable law. If the reader of this message is 
> not the intended recipient or the employee or agent responsible for 
> delivering the message to the intended recipient, you are hereby notified 
> that any dissemination, distribution or copying of this communication is 
> strictly prohibited. If you have received this communication in error, please 
> contact the sender immediately and destroy the material in its entirety, 
> whether electronic or hard copy. Thank you.
> 
>

===


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Re: [Freesurfer] Question about running recon-all with deface

2015-12-15 Thread Bruce Fischl
I see. That is surprisingly large for whole structure volumes. We don't 
have a lot of experience analyzing defaced volumes, so I would do recon-all 
on the original data, then deface post-hoc. If you upload one subject where 
you find a large (or the largest) difference, I'll take  alook


On Tue, 15 Dec 2015, Mishra, Virendra wrote:


Hi Bruce,

When the thickness/volume measure was compared between the results obtained 
with recon-all with and without defaced T1 as input to recon-all, we obtained 
20% errors (between them)

Example: 100*(Thalamus_left_volume_with_defaced_T1_to_recon-all MINUS  
Thalamus_left_volume_without_deface_T1_to_recon_all)/( 
thalamus_left_volume_without_deface_T1_to_recon_all)

We think, we would rather run recon-all with the face but use -deface flag 
during recon-all.

Thanks

Regards

Virendra

-Original Message-
From: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Bruce Fischl
Sent: Monday, December 14, 2015 10:05 AM
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] Question about running recon-all with deface

Hi Virenda

can you say what you mean by 20% errors? Compared to what? Note for example 
that a 20% variation in the thickness at one spot would mean a change of 0.4mm 
(for 2mm thick cortex). Seeing this type of variation point-wise somewhere in 
the brain isn't terribly surprising, although I wish it were less. Defacing 
will definitely change things (e.g. skull stripping, bias estimation and 
removal, etc...)

cheers
Bruce
On Mon, 14 Dec 2015, Mishra,
Virendra wrote:



Hi,

 

I will appreciate if somebody could reply to my message that was posted 
earlier. I copy-paste the message here again.

 

We are currently in the process of analyzing some data that was
defaced using mri_deface command of freesurfer. This defaced data was
then used as an input to recon-all and the volume and thickness was
computed. These results were then compared against the same subject’s
recon-all with the face but with and without the deface flag within
recon-all. All of the steps were done on version 5.3.0 on CentOS. We have got 
some differences and we are unable to explain why. Some of the regions have 
error greater than 20% when the input was a defaced brain. We would appreciate 
if you could advise as to how to approach to the same results as we were 
running the data with the face .

 

To summarize: (The commands are not precise below but we ensured the
commands are run correctly per the command help)

1)  Step 1: mri_deface -i original_T1 -o deface_T1

2)  Step 2: recon-all -i deface_T1

3)  Step 3: recon-all –i original_T1 –deface

4)  Step 4: recon-all –i original_T1

5)  The results from Step 3 is exactly equal to Step 4

6)  The results from Step 2 and Step3/4 have errors >20% in certain regions.

7)  Step 1-4 are done with version 5.3.0

 

Any response will be greatly appreciated.

 

 

Thanks

 

Regards

 

Virendra

===

Please consider the environment before printing this e-mail

Cleveland Clinic is ranked as one of the top hospitals in America by
U.S.News & World Report (2015). Visit us online at
http://www.clevelandclinic.org for a complete listing of our services,
staff and locations. Confidentiality Note: This message is intended
for use only by the individual or entity to which it is addressed and
may contain information that is privileged, confidential, and exempt
from disclosure under applicable law. If the reader of this message is
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the message to the intended recipient, you are hereby notified that any 
dissemination, distribution or copying of this communication is strictly 
prohibited. If you have received this communication in error, please contact 
the sender immediately and destroy the material in its entirety, whether 
electronic or hard copy. Thank you.




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Visit us online at http://www.clevelandclinic.org for a complete listing of our 
services, staff and locations.


Confidentiality Note:  This message is intended for use only by the individual 
or entity to which it is addressed and may contain information that is 
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the reader of this message is not the intended recipient or the employee or 
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[Freesurfer] Question about running recon-all with deface

2015-12-14 Thread Mishra, Virendra
Hi,

I will appreciate if somebody could reply to my message that was posted 
earlier. I copy-paste the message here again.

We are currently in the process of analyzing some data that was defaced using 
mri_deface command of freesurfer. This defaced data was then used as an input 
to recon-all and the volume and thickness was computed. These results were then 
compared against the same subject's recon-all with the face but with and 
without the deface flag within recon-all. All of the steps were done on version 
5.3.0 on CentOS. We have got some differences and we are unable to explain why. 
Some of the regions have error greater than 20% when the input was a defaced 
brain. We would appreciate if you could advise as to how to approach to the 
same results as we were running the data with the face .

To summarize: (The commands are not precise below but we ensured the commands 
are run correctly per the command help)

1)  Step 1: mri_deface -i original_T1 -o deface_T1

2)  Step 2: recon-all -i deface_T1

3)  Step 3: recon-all -i original_T1 -deface

4)  Step 4: recon-all -i original_T1

5)  The results from Step 3 is exactly equal to Step 4

6)  The results from Step 2 and Step3/4 have errors >20% in certain regions.

7)  Step 1-4 are done with version 5.3.0

Any response will be greatly appreciated.


Thanks

Regards

Virendra

===


 Please consider the environment before printing this e-mail

Cleveland Clinic is ranked as one of the top hospitals in America by U.S.News & 
World Report (2015).  
Visit us online at http://www.clevelandclinic.org for a complete listing of our 
services, staff and locations.


Confidentiality Note:  This message is intended for use only by the individual 
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Re: [Freesurfer] Question about running recon-all with deface

2015-12-14 Thread Bruce Fischl

Hi Virenda

can you say what you mean by 20% errors? Compared to what? Note for 
example that a 20% variation in the thickness at one spot would mean a 
change of 0.4mm (for 2mm thick cortex). Seeing this type of variation 
point-wise somewhere in the brain isn't terribly surprising, although I 
wish it were less. Defacing will definitely change things (e.g. skull 
stripping, bias estimation and removal, etc...)


cheers
Bruce
On Mon, 14 Dec 2015, Mishra, 
Virendra wrote:




Hi,

 

I will appreciate if somebody could reply to my message that was posted 
earlier. I copy-paste the message here again.

 

We are currently in the process of analyzing some data that was defaced using 
mri_deface command of freesurfer. This defaced
data was then used as an input to recon-all and the volume and thickness was 
computed. These results were then compared against
the same subject’s recon-all with the face but with and without the deface flag 
within recon-all. All of the steps were done on
version 5.3.0 on CentOS. We have got some differences and we are unable to 
explain why. Some of the regions have error greater
than 20% when the input was a defaced brain. We would appreciate if you could 
advise as to how to approach to the same results
as we were running the data with the face .

 

To summarize: (The commands are not precise below but we ensured the commands 
are run correctly per the command help)

1)  Step 1: mri_deface -i original_T1 -o deface_T1

2)  Step 2: recon-all -i deface_T1

3)  Step 3: recon-all –i original_T1 –deface

4)  Step 4: recon-all –i original_T1

5)  The results from Step 3 is exactly equal to Step 4

6)  The results from Step 2 and Step3/4 have errors >20% in certain regions.

7)  Step 1-4 are done with version 5.3.0  

 

Any response will be greatly appreciated.

 

 

Thanks

 

Regards

 

Virendra

===

Please consider the environment before printing this e-mail

Cleveland Clinic is ranked as one of the top hospitals in America by U.S.News & 
World Report (2015). Visit us online at
http://www.clevelandclinic.org for a complete listing of our services, staff 
and locations. Confidentiality Note: This message
is intended for use only by the individual or entity to which it is addressed 
and may contain information that is privileged,
confidential, and exempt from disclosure under applicable law. If the reader of 
this message is not the intended recipient or
the employee or agent responsible for delivering the message to the intended 
recipient, you are hereby notified that any
dissemination, distribution or copying of this communication is strictly 
prohibited. If you have received this communication in
error, please contact the sender immediately and destroy the material in its 
entirety, whether electronic or hard copy. Thank
you.

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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
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[Freesurfer] Question about running recon-all with deface

2015-12-10 Thread Mishra, Virendra
Hello,

We are currently in the process of analyzing some data that was defaced using 
mri_deface command of freesurfer. This defaced data was then used as an input 
to recon-all and the volume and thickness was computed. These results were then 
compared against the same subject's recon-all with the face but with and 
without the deface flag within recon-all. All of the steps were done on version 
5.3.0. We have got some differences and we are unable to explain why. Some of 
the regions have error greater than 20% when the input was a defaced brain. We 
would appreciate if you could advise as to how to approach to the same results 
as we were running the data with the face .

To summarize: (The commands are not precise below but we ensured the commands 
are run correctly per the command help)

1)  Step 1: mri_deface -i original_T1 -o deface_T1

2)  Step 2: recon-all -i deface_T1

3)  Step 3: recon-all -i original_T1 -deface

4)  Step 4: recon-all -i original_T1

5)  The results from Step 3 is exactly equal to Step 4

6)  The results from Step 2 and Step3/4 have errors >20% in certain regions.

7)  Step 1-4 are done with version 5.3.0

Any response will be greatly appreciated.

Thanks

Regards

Virendra

===


 Please consider the environment before printing this e-mail

Cleveland Clinic is ranked as one of the top hospitals in America by U.S.News & 
World Report (2015).  
Visit us online at http://www.clevelandclinic.org for a complete listing of our 
services, staff and locations.


Confidentiality Note:  This message is intended for use only by the individual 
or entity to which it is addressed and may contain information that is 
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the reader of this message is not the intended recipient or the employee or 
agent responsible for delivering the message to the intended recipient, you are 
hereby notified that any dissemination, distribution or copying of this 
communication is strictly prohibited.  If you have received this communication 
in error,  please contact the sender immediately and destroy the material in 
its entirety, whether electronic or hard copy.  

Thank you.
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