Re: [Freesurfer] WM volume

2021-02-26 Thread Douglas N. Greve

Yes (excluding ventricles, of course)

On 2/23/2021 3:27 PM, Barletta, Valeria wrote:
Thanks a lot. One more thing, is the total brain volume 
"BrainSegVolNotVent, Brain Segmentation Volume Without Ventricles" ?


Valeria Barletta, MD
Massachusetts General Hospital
149 13th Street, Charlestown MA 02129
(617)-724-8823

*From:* freesurfer-boun...@nmr.mgh.harvard.edu 
 on behalf of Douglas N. Greve 


*Sent:* Tuesday, February 23, 2021 9:10 AM
*To:* freesurfer@nmr.mgh.harvard.edu 
*Subject:* Re: [Freesurfer] WM volume
Yes, that is the right value. We changed the name of it in more recent 
versions to CerebralWhiteMatter


On 2/22/2021 4:12 PM, Barletta, Valeria wrote:

Dear Freesurfers,
In what file inside the patient_name/stats folder do I find the total 
white matter volume?
In the file "aseg.stats" there is something called lh/rh "cortical 
white matter volume", is that the right value to look at?


Thank you,

Valeria Barletta, MD
Massachusetts General Hospital
149 13th Street, Charlestown MA 02129
(617)-724-8823

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Re: [Freesurfer] WM volume

2021-02-23 Thread Barletta, Valeria
Thanks a lot. One more thing, is the total brain volume "BrainSegVolNotVent, 
Brain Segmentation Volume Without Ventricles" ?

Valeria Barletta, MD
Massachusetts General Hospital
149 13th Street, Charlestown MA 02129
(617)-724-8823

From: freesurfer-boun...@nmr.mgh.harvard.edu 
 on behalf of Douglas N. Greve 

Sent: Tuesday, February 23, 2021 9:10 AM
To: freesurfer@nmr.mgh.harvard.edu 
Subject: Re: [Freesurfer] WM volume

Yes, that is the right value. We changed the name of it in more recent versions 
to CerebralWhiteMatter

On 2/22/2021 4:12 PM, Barletta, Valeria wrote:
Dear Freesurfers,
In what file inside the patient_name/stats folder do I find the total white 
matter volume?
In the file "aseg.stats" there is something called lh/rh "cortical white matter 
volume", is that the right value to look at?

Thank you,

Valeria Barletta, MD
Massachusetts General Hospital
149 13th Street, Charlestown MA 02129
(617)-724-8823



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Re: [Freesurfer] WM volume

2021-02-23 Thread Douglas N. Greve
Yes, that is the right value. We changed the name of it in more recent 
versions to CerebralWhiteMatter


On 2/22/2021 4:12 PM, Barletta, Valeria wrote:

Dear Freesurfers,
In what file inside the patient_name/stats folder do I find the total 
white matter volume?
In the file "aseg.stats" there is something called lh/rh "cortical 
white matter volume", is that the right value to look at?


Thank you,

Valeria Barletta, MD
Massachusetts General Hospital
149 13th Street, Charlestown MA 02129
(617)-724-8823

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[Freesurfer] WM volume

2021-02-22 Thread Barletta, Valeria
Dear Freesurfers,
In what file inside the patient_name/stats folder do I find the total white 
matter volume?
In the file "aseg.stats" there is something called lh/rh "cortical white matter 
volume", is that the right value to look at?

Thank you,

Valeria Barletta, MD
Massachusetts General Hospital
149 13th Street, Charlestown MA 02129
(617)-724-8823
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Re: [Freesurfer] WM Volume

2017-06-19 Thread Bruce Fischl
nope, as long as the white surface is accurate you should be all set.

cheers
Bruce


On 
Mon, 19 Jun 2017, Michael Davies wrote:

> 
> Hello, i am currently looking at the WM Volume in heat mode and am curious
> as to if i need to fill in all the small missing voxels located within the
> boundary as well as the bigger holes?
> 
> 
> Kind regards, Michael
> 
> 
>
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[Freesurfer] WM Volume

2017-06-19 Thread Michael Davies
Hello, i am currently looking at the WM Volume in heat mode and am curious as 
to if i need to fill in all the small missing voxels located within the 
boundary as well as the bigger holes?


Kind regards, Michael
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Re: [Freesurfer] wm- volume limitations

2015-07-08 Thread Krieger, Donald N.
Great - just what I was looking for - thanks.

Regards,

Don

[Signature0001]
Don Krieger, Ph.D.
Department of Neurological Surgery
University of Pittsburgh
(412)648-9654 Office
(412)521-4431 Cell/Text

From: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Douglas Greve
Sent: Tuesday, July 07, 2015 10:18 PM
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] wm- volume limitations


the wmparc gets the cortical parcellation of the closest cortical parcellation 
(not necessarily normal to the surface). I think it has to be within 5mm of 
cortex or else it gets Unsegmented White Matter. The method is described here

http://www.ncbi.nlm.nih.gov/pubmed/19027860



On 7/7/15 8:36 PM, Krieger, Donald N. wrote:
Freesurfer provides ctx- and wm- volumes on either side of the white labelled 
sheet, all for a particular cortical region.
What is the idea which is used to limit the extent of the wm- volume which is 
adjacent to a particular ctx- volume?
Is it as simple as a maximum distance normal to  the white matter sheet?
I'm sure this is documented somewhere but I haven't been able to find it.
Thanks.

Don





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[Freesurfer] wm- volume limitations

2015-07-07 Thread Krieger, Donald N.
Freesurfer provides ctx- and wm- volumes on either side of the white labelled 
sheet, all for a particular cortical region.
What is the idea which is used to limit the extent of the wm- volume which is 
adjacent to a particular ctx- volume?
Is it as simple as a maximum distance normal to  the white matter sheet?
I'm sure this is documented somewhere but I haven't been able to find it.
Thanks.

Don

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Re: [Freesurfer] wm- volume limitations

2015-07-07 Thread Douglas Greve


the wmparc gets the cortical parcellation of the closest cortical 
parcellation (not necessarily normal to the surface). I think it has to 
be within 5mm of cortex or else it gets Unsegmented White Matter. The 
method is described here


http://www.ncbi.nlm.nih.gov/pubmed/19027860




On 7/7/15 8:36 PM, Krieger, Donald N. wrote:


Freesurfer provides ctx- and wm- volumes on either side of the “white” 
labelled sheet, all for a particular cortical region.


What is the idea which is used to limit the extent of the wm- volume 
which is adjacent to a particular ctx- volume?


Is it as simple as a maximum distance normal to  the white matter sheet?

I’m sure this is documented somewhere but I haven’t been able to find it.

Thanks.

Don



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[Freesurfer] WM volume estimation - image capture

2008-04-30 Thread Damian Jenkins
Whilst estimating white matter volume using mris_wm_volume is it possible to 
save an image for inspection?

Dr Damian Jenkins
Department of Clinical Neurology
Oxford University

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Re: [Freesurfer] WM volume estimation - image capture

2008-04-30 Thread Bruce Fischl

what kind of image do you mean?
On Wed, 30 Apr 2008, Damian Jenkins wrote:


Whilst estimating white matter volume using mris_wm_volume is it possible to 
save an image for inspection?

Dr Damian Jenkins
Department of Clinical Neurology
Oxford University

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RE: [Freesurfer] WM volume CSF BPF

2007-10-26 Thread Gallo, Antonio (NIH/NINDS) [F]
Hi Bruce,

Thanks for your prompt reply.

Could you please further clarify some points below ?

 

-Original Message-

From: Bruce Fischl [mailto:[EMAIL PROTECTED]

Sent: Thursday, October 25, 2007 8:38 PM

To: Gallo, Antonio (NIH/NINDS) [F]

Cc: freesurfer@nmr.mgh.harvard.edu

Subject: Re: [Freesurfer] WM volume  CSF  BPF

 

On Thu, 25 Oct 2007, Gallo, Antonio (NIH/NINDS) [F] wrote:

 

 Dear All,

 

 We are dealing with MPRAGE data acquired at a 3.0T MRI scanner and

 analyzed with FS 3.0.5.

 

 Images belong to a group of Multiple Sclerosis patients.

 

 

 

 We would like to ask some questions and we apologize for the fact
that

 we have quite a number of them :-)

 

 First, regarding measurements coming from mris_anatomical_stats:

 

 1)   What is exactly included in total WM volume?

 

in mris_anatomical_stats this is the total volume occupied by voxels in
the

wm.mgz volume that are on.  We now use mris_wm_volume to compute the

volume using the surfaces, which we believe is more accurate.

 

In WM.mgz file I can see on ventricles, deep nuclei, brainstem and
off (zeroed) some little spots that don't correspond to WM lesions and
are not enclosed by any surface contour (so we didn't correct).

Since we would like to stay on FS 3.0.5, at least for now, could you
please better clarify what does WM volume refer to?

 

 

 2)   Is total WM volume  the sum of left and right WM hemisphere
or

 just the WM volume from the side we specify (but if this is case, why
we

 got the same values after running mris_anatomical_stats for lh and rh

 hemisphere) ?

 

there is no lateralization in this calculation, but you could use the

aseg.mgz to get lh and rh volumes (in the aseg.stats file)

 

 

 3)   Since there are many WM lesions (with many juxta-cortical

 lesions that need manual editing), we were wondering if total WM
volume

 does include the WM hypointensities as well or those are just treated

 separately.

 

it depends whether they were classified as wm in the wm.mgz. If you use
the

mris_wm_volume  method, then the hypointensities *will* be included in
the

volume.

 

 

 4)   Does the total GM volume include the volume of the
subcortical

 structures and cerebellum or just refer to the cortical GM volume?

 

just cortical GM.

 

 

 

 

 Second, some other questions on the aseg.stat file:

 

 1)   What is exactly included in CSF label? Does it comprehend
the

 CSF in the ventricles + the sulcal CSF, or just the the sulcal CSF?

 

CSF is sulcal CSF and we don't label very much of it, as you can't
really

see it well on a T1-weighted MRI. The ventricles have their volumes
given

individually.

 

  

 2)   Does the volume of the WM hypointensities manually edited

 (which happens very often with MS lesions close to the cortex) end up
in

 the WM hypointensities volume?

 

if they are labeled as hypointensities in the aseg.mgz. Are you
manually

editing them there or in the wm.mgz?

 

 

We use to edit the WM lesions (mainly for the ones close to the cortex)
by using control points and checking that the ?h.white looks fine
(staying at the edge of the lesion and not inside.

Should we correct the WM lesions differently?  

 

 

 

 Last, as we are interested in measuring subjects' BPF, we were
wondering

 which would be the best way to compute it?

 

Could you suggest to us the best way to compute the BPF ?

 

 

 

 Thanks a lot in advance, (again)

 

 

 

 Antonio

 

 

 

 

 

 Antonio Gallo, MD

 

 NIB-NINDS-NIH

 

 10 Center Drive

 

 Building 10, Room 5B16

 

 Bethesda, MD, 20892 - USA

 

 ph #: 001-301-402.6391

 

 fax #: 001-301-402.0373

 

 ***

 

 

 

 

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[Freesurfer] WM volume CSF BPF

2007-10-25 Thread Gallo, Antonio (NIH/NINDS) [F]
Dear All,

We are dealing with MPRAGE data acquired at a 3.0T MRI scanner and
analyzed with FS 3.0.5.

Images belong to a group of Multiple Sclerosis patients. 

 

We would like to ask some questions and we apologize for the fact that
we have quite a number of them :-)

 

First, regarding measurements coming from mris_anatomical_stats:

1)   What is exactly included in total WM volume?

2)   Is total WM volume  the sum of left and right WM hemisphere or
just the WM volume from the side we specify (but if this is case, why we
got the same values after running mris_anatomical_stats for lh and rh
hemisphere) ?

3)   Since there are many WM lesions (with many juxta-cortical
lesions that need manual editing), we were wondering if total WM volume
does include the WM hypointensities as well or those are just treated
separately.

4)   Does the total GM volume include the volume of the subcortical
structures and cerebellum or just refer to the cortical GM volume?

 

Second, some other questions on the aseg.stat file:

1)   What is exactly included in CSF label? Does it comprehend the
CSF in the ventricles + the sulcal CSF, or just the the sulcal CSF?

2)   Does the volume of the WM hypointensities manually edited
(which happens very often with MS lesions close to the cortex) end up in
the WM hypointensities volume?

 

Last, as we are interested in measuring subjects' BPF, we were wondering
which would be the best way to compute it?

 

Thanks a lot in advance,

 

Antonio

 

 

Antonio Gallo, MD

NIB-NINDS-NIH

10 Center Drive

Building 10, Room 5B16

Bethesda, MD, 20892 - USA

ph #: 001-301-402.6391

fax #: 001-301-402.0373

***

 

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Re: [Freesurfer] WM volume CSF BPF

2007-10-25 Thread Bruce Fischl

On Thu, 25 Oct 2007, Gallo, Antonio (NIH/NINDS) [F] wrote:


Dear All,

We are dealing with MPRAGE data acquired at a 3.0T MRI scanner and
analyzed with FS 3.0.5.

Images belong to a group of Multiple Sclerosis patients.



We would like to ask some questions and we apologize for the fact that
we have quite a number of them :-)

First, regarding measurements coming from mris_anatomical_stats:

1)   What is exactly included in total WM volume?


in mris_anatomical_stats this is the total volume occupied by voxels in the 
wm.mgz volume that are on.  We now use mris_wm_volume to compute the 
volume using the surfaces, which we believe is more accurate.



2)   Is total WM volume  the sum of left and right WM hemisphere or
just the WM volume from the side we specify (but if this is case, why we
got the same values after running mris_anatomical_stats for lh and rh
hemisphere) ?


there is no lateralization in this calculation, but you could use the 
aseg.mgz to get lh and rh volumes (in the aseg.stats file)




3)   Since there are many WM lesions (with many juxta-cortical
lesions that need manual editing), we were wondering if total WM volume
does include the WM hypointensities as well or those are just treated
separately.


it depends whether they were classified as wm in the wm.mgz. If you use the 
mris_wm_volume  method, then the hypointensities *will* be included in the 
volume.




4)   Does the total GM volume include the volume of the subcortical
structures and cerebellum or just refer to the cortical GM volume?


just cortical GM.





Second, some other questions on the aseg.stat file:

1)   What is exactly included in CSF label? Does it comprehend the
CSF in the ventricles + the sulcal CSF, or just the the sulcal CSF?


CSF is sulcal CSF and we don't label very much of it, as you can't really 
see it well on a T1-weighted MRI. The ventricles have their volumes given 
individually.


 

2)   Does the volume of the WM hypointensities manually edited
(which happens very often with MS lesions close to the cortex) end up in
the WM hypointensities volume?


if they are labeled as hypointensities in the aseg.mgz. Are you manually 
editing them there or in the wm.mgz?




Last, as we are interested in measuring subjects' BPF, we were wondering
which would be the best way to compute it?



Thanks a lot in advance,



Antonio





Antonio Gallo, MD

NIB-NINDS-NIH

10 Center Drive

Building 10, Room 5B16

Bethesda, MD, 20892 - USA

ph #: 001-301-402.6391

fax #: 001-301-402.0373

***





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[Freesurfer] wm volume

2005-05-05 Thread Lars Tjelta Westlye
Hi all,

is there a way I can attain the total wm volume for each of the
hemispheres?  And is it possible to estimate the wm volume of certain
gross anatomical areas, like the different lobes?

Thanks!



Best wishes,
Lars Tjelta Westlye

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Re: [Freesurfer] wm volume

2005-05-05 Thread Bruce Fischl
you can get an estimate by loading the filled volume into matlab and 
counting the # of 127 (rh) and 255 (lh). Nothing lobar though - what would 
it mean? Where would you draw the borders?

cheers,
Bruce
On Thu, 5 May 2005, Lars Tjelta 
Westlye wrote:

Hi all,
is there a way I can attain the total wm volume for each of the
hemispheres?  And is it possible to estimate the wm volume of certain
gross anatomical areas, like the different lobes?
Thanks!

Best wishes,
Lars Tjelta Westlye
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Re: [Freesurfer] wm volume

2005-05-05 Thread Bruce Fischl
sure. There are white matter parcellation schemes around, but we don't 
have one at the moment.

cheers,
Bruce
On Thu, 5 May 2005, Lars Tjelta Westlye wrote:
Thanks for your swift reply, Bruce!
I don't know how the lobar drawing would be done, but am curious if there
exist any kind of 'predefined regions' that could further refine the
estimates of the total wm volume. It could be interesting to estimate
where the wm loss is most prominent in aging, for example. I don't know if
this is something that is easily done, though.
Thanks again!
Lars

you can get an estimate by loading the filled volume into matlab and
counting the # of 127 (rh) and 255 (lh). Nothing lobar though - what would
it mean? Where would you draw the borders?
cheers,
Bruce
On Thu, 5 May 2005, Lars Tjelta
Westlye wrote:
Hi all,
is there a way I can attain the total wm volume for each of the
hemispheres?  And is it possible to estimate the wm volume of certain
gross anatomical areas, like the different lobes?
Thanks!

Best wishes,
Lars Tjelta Westlye

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