Re: [Freesurfer] help needed with fsgd file and contrast matrix for correlation analysis

2013-07-23 Thread Douglas Greve 


Hi Robert, both of those are correct. The 2nd will give you 
OldAgeSlope-YoungAgeSlope correcting for Gender and BEH

doug



On 7/23/13 10:40 AM, Robert Schulz wrote:

Dear all,
I have 2 short questions regarding a correlation analysis I'd like to 
perform with mri_glmfit (surface-based DTI data are correctly 
preprocessed and concatenated into mgh file, statistics are performed 
on fsaverage space).
1) I'd like to look for correlation between the surface-data and a 
behavioural measure BEH in one group, correcting for gender and age.

I set up the following fsgd:
GroupDescriptorFile 1
Class Male
Class Female
Variables BEH Age
Input subj1 Male 0.76 72
Input subj2 Male 0.44 67
Input subj3 Female 0.33 80

My contrast file is: 0 0 0.5 0.5 0 0 (referring to the FSGD examples 
Fsgd2G2V, GLM with 2*(2+1) columns).

Is this setup correct? If not, how would I have to set up fsgd and C?
2) In a next step, I'd like to answer the question (now including 
another group2): Where does group1 (OLD) show increased correlation 
with BEH compared to group2 (YOUNG), correcting for GENDER and AGE 
within each group. I wonder because AGE is the relevant difference 
between both groups.

GroupDescriptorFile 1
Class OldMale
Class OldFemale
Class YoungMale
Class YoungFemale
Variables BEH Age
Input subj1 OldMale 0.76 72
Input subj2 OldMale 0.44 67
Input subj3 OldFemale 0.33 80

Input subj11 YoungMale 0.80 20
Input subj12 YoungMale 0.55 21
Input subj13 YoungFemale 0.44 31

My contrast file would look like: 0 0 0 0 0.5 0.5 -0.5 -0.5 0 0 0 0 
(referring to GLM with 4*(2+1) columns).

Correct?
Thank you very much for your help! I am really not sure whether I did 
it correctly and whether I can trust my results.

Best wishes, Robert

Besuchen Sie uns auf: www.uke.de 



Universitätsklinikum Hamburg-Eppendorf; Körperschaft des öffentlichen 
Rechts; Gerichtsstand: Hamburg
Vorstandsmitglieder: Prof. Dr. Martin Zeitz (Vorsitzender), Prof. Dr. 
Dr. Uwe Koch-Gromus, Astrid Lurati (komm.), Joachim Prölß, Matthias 
Waldmann (komm.)




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[Freesurfer] help needed with fsgd file and contrast matrix for correlation analysis

2013-07-23 Thread Robert Schulz 
Dear all, 

I have 2 short questions regarding a correlation analysis I'd like to perform 
with mri_glmfit (surface-based DTI data are correctly preprocessed and 
concatenated into mgh file, statistics are performed on fsaverage space). 

1) I'd like to look for correlation between the surface-data and a behavioural 
measure BEH in one group, correcting for gender and age. 

I set up the following fsgd: 

GroupDescriptorFile 1
Class Male
Class Female
Variables BEH Age
Input subj1 Male 0.76 72
Input subj2 Male 0.44 67
Input subj3 Female 0.33 80


My contrast file is: 0 0 0.5 0.5 0 0 (referring to the FSGD examples Fsgd2G2V, 
GLM with 2*(2+1) columns).
Is this setup correct? If not, how would I have to set up fsgd and C?



2) In a next step, I'd like to answer the question (now including another 
group2): Where does group1 (OLD) show increased correlation with BEH compared 
to group2 (YOUNG), correcting for GENDER and AGE within each group. I wonder 
because AGE is the relevant difference between both groups. 

GroupDescriptorFile 1
Class OldMale
Class OldFemale
Class YoungMale
Class YoungFemale
Variables BEH Age
Input subj1 OldMale 0.76 72
Input subj2 OldMale 0.44 67
Input subj3 OldFemale 0.33 80

Input subj11 YoungMale 0.80 20
Input subj12 YoungMale 0.55 21
Input subj13 YoungFemale 0.44 31


My contrast file would look like: 0 0 0 0 0.5 0.5 -0.5 -0.5 0 0 0 0 (referring 
to GLM with 4*(2+1) columns).
Correct?

Thank you very much for your help! I am really not sure whether I did it 
correctly and whether I can trust my results. 

Best wishes, Robert
--

Besuchen Sie uns auf: www.uke.de
_

Universitätsklinikum Hamburg-Eppendorf; Körperschaft des öffentlichen Rechts; 
Gerichtsstand: Hamburg
Vorstandsmitglieder: Prof. Dr. Martin Zeitz (Vorsitzender), Prof. Dr. Dr. Uwe 
Koch-Gromus, Astrid Lurati (komm.), Joachim Prölß, Matthias Waldmann (komm.)
_

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dispose of the e-mail.

[Freesurfer] help needed with fsgd file and contrast matrix for correlation analysis

2013-07-23 Thread Robert Schulz 
Dear all, 

I have 2 short questions regarding a correlation analysis I'd like to perform 
with mri_glmfit (surface-based DTI data are correctly preprocessed and 
concatenated into mgh file, statistics are performed on fsaverage space). 

1) I'd like to look for correlation between the surface-data and a behavioural 
measure BEH in one group, correcting for gender and age. 

I set up the following fsgd: 

GroupDescriptorFile 1
Class Male
Class Female
Variables BEH Age
Input subj1 Male 0.76 72
Input subj2 Male 0.44 67
Input subj3 Female 0.33 80


My contrast file is: 0 0 0.5 0.5 0 0 (referring to the FSGD examples Fsgd2G2V, 
GLM with 2*(2+1) columns).
Is this setup correct? If not, how would I have to set up fsgd and C?



2) In a next step, I'd like to answer the question (now including another 
group2): Where does group1 (OLD) show increased correlation with BEH compared 
to group2 (YOUNG), correcting for GENDER and AGE within each group. I wonder 
because AGE is the relevant difference between both groups. 

GroupDescriptorFile 1
Class OldMale
Class OldFemale
Class YoungMale
Class YoungFemale
Variables BEH Age
Input subj1 OldMale 0.76 72
Input subj2 OldMale 0.44 67
Input subj3 OldFemale 0.33 80

Input subj11 YoungMale 0.80 20
Input subj12 YoungMale 0.55 21
Input subj13 YoungFemale 0.44 31


My contrast file would look like: 0 0 0 0 0.5 0.5 -0.5 -0.5 0 0 0 0 (referring 
to GLM with 4*(2+1) columns).
Correct?

Thank you very much for your help! I am really not sure whether I did it 
correctly and whether I can trust my results. 

--

Besuchen Sie uns auf: www.uke.de
_

Universitätsklinikum Hamburg-Eppendorf; Körperschaft des öffentlichen Rechts; 
Gerichtsstand: Hamburg
Vorstandsmitglieder: Prof. Dr. Martin Zeitz (Vorsitzender), Prof. Dr. Dr. Uwe 
Koch-Gromus, Astrid Lurati (komm.), Joachim Prölß, Matthias Waldmann (komm.)
_

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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.