Re: [Freesurfer] single subject versus a group map in qdec

[Douglas N Greve]

Hi Emily, it is just performing a two "group" analysis, where one of 
your groups only has a single subject. There is nothing wrong with what 
you did, it all comes down to what conclusion you are trying to draw 
from it. I think it is ok for a case report.
doug

Emily Rogalski wrote:
> Using q dec we have run a single patient versus a group of healthy 
> control subjects (n=20ish) and found significant differences even 
> after FDR correction.
>
> Could you describe the process qdec uses to compute these differences?
> Is it legitimate to report these single subject maps?
> Practically this is very useful for case reports but Im concerned 
> about violating statistical rules.
>
> Thanks!
> -- 
> Emily J Rogalski, PhD
> Assistant Research Professor
> Northwestern University
> Cognitive Neurology and Alzheimer's Disease Center (CNADC)
> 320 E Superior Street
> Searle Building 11th Floor
> Chicago, IL 60611
> 312-503-1155 phone
> 312-908-8789 fax
> erogal...@gmail.com 
> 
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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Re: [Freesurfer] single subject versus a group map in qdec

[Derin Cobia]

I'm curious about the use of this method as well (thanks for the paper PPJ).  
Bruce/Doug, how exactly does QDEC treat this design?  Can a single-subject 
comparison properly be done?  Thanks.  

-Derin


On Mar 23, 2011, at 4:11 PM, Pedro Paulo de Magalhães Oliveira Junior wrote:

> We have dono something like this in Cortical thickness reduction of normal 
> appearing cortex in patients with polymicrogyria
> 
> cheers,
> 
> PPJ
> -
> Pedro Paulo de Magalhães Oliveira Junior
> Diretor de Operações
> Netfilter & SpeedComm Telecom
> -- www.netfilter.com.br
> -- For mobile: http://www.netfilter.com.br/mobile
> 
> 
> 
> 
> On Wed, Mar 23, 2011 at 14:21, Emily Rogalski  wrote:
> Using q dec we have run a single patient versus a group of healthy control 
> subjects (n=20ish) and found significant differences even after FDR 
> correction.
> 
> Could you describe the process qdec uses to compute these differences? 
> Is it legitimate to report these single subject maps?
> Practically this is very useful for case reports but Im concerned about 
> violating statistical rules. 
> 
> Thanks!
> -- 
> Emily J Rogalski, PhD
> Assistant Research Professor
> Northwestern University
> Cognitive Neurology and Alzheimer's Disease Center (CNADC)
> 320 E Superior Street
> Searle Building 11th Floor
> Chicago, IL 60611
> 312-503-1155 phone
> 312-908-8789 fax
> erogal...@gmail.com
> 
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> Freesurfer mailing list
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> 
> 
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> contains patient information, please contact the Partners Compliance HelpLine 
> at
> http://www.partners.org/complianceline . If the e-mail was sent to you in 
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Re: [Freesurfer] single subject versus a group map in qdec

[Pedro Paulo de Magalhães Oliveira Junior]

We have dono something like this in Cortical thickness reduction of normal
appearing cortex in patients with
polymicrogyria


cheers,

PPJ
-
Pedro Paulo de Magalhães Oliveira Junior
Diretor de Operações
Netfilter & SpeedComm Telecom
-- www.netfilter.com.br
-- For mobile: http://www.netfilter.com.br/mobile




On Wed, Mar 23, 2011 at 14:21, Emily Rogalski  wrote:

> Using q dec we have run a single patient versus a group of healthy control
> subjects (n=20ish) and found significant differences even after FDR
> correction.
>
> Could you describe the process qdec uses to compute these differences?
> Is it legitimate to report these single subject maps?
> Practically this is very useful for case reports but Im concerned about
> violating statistical rules.
>
> Thanks!
> --
> Emily J Rogalski, PhD
> Assistant Research Professor
> Northwestern University
> Cognitive Neurology and Alzheimer's Disease Center (CNADC)
> 320 E Superior Street
> Searle Building 11th Floor
> Chicago, IL 60611
> 312-503-1155 phone
> 312-908-8789 fax
> erogal...@gmail.com
>
> ___
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
>
> The information in this e-mail is intended only for the person to whom it
> is
> addressed. If you believe this e-mail was sent to you in error and the
> e-mail
> contains patient information, please contact the Partners Compliance
> HelpLine at
> http://www.partners.org/complianceline . If the e-mail was sent to you in
> error
> but does not contain patient information, please contact the sender and
> properly
> dispose of the e-mail.
>
>
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[Freesurfer] single subject versus a group map in qdec

[Emily Rogalski]

Using q dec we have run a single patient versus a group of healthy control
subjects (n=20ish) and found significant differences even after FDR
correction.

Could you describe the process qdec uses to compute these differences?
Is it legitimate to report these single subject maps?
Practically this is very useful for case reports but Im concerned about
violating statistical rules.

Thanks!
-- 
Emily J Rogalski, PhD
Assistant Research Professor
Northwestern University
Cognitive Neurology and Alzheimer's Disease Center (CNADC)
320 E Superior Street
Searle Building 11th Floor
Chicago, IL 60611
312-503-1155 phone
312-908-8789 fax
erogal...@gmail.com
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