Re: [Freesurfer] Clusters locations

2012-02-14 Thread Douglas Greve
Hi Antonella, what level of detail do you want? I think that most people 
are reporting MNI coordinates.

doug

On 2/13/12 2:44 PM, Antonella Kis wrote:

Hi Doug,

I will be very grateful if you give me some directions regarding how I 
can get my clusters location ( my output is too general telling me 
just Left-Cerebral-White-Matter and Right-Cerebral-White-Matter) and 
the coordinates (MNI) when I run the:


mri_volcluster --in GroupAnalysis_pos.glmdir/contrast/sig.mgh --mask 
GroupAnalysis_pos.glmdir/mask.mgh --no-fixmni --cwsig 
GroupAnalysis_pos.glmdir/contrast/permcsd.sig.cluster.mgh --sum 
GroupAnalysis_pos.glmdir/contrast/permcsd.sig.cluster.summary --ocn 
GroupAnalysis_pos.glmdir/contrast/permcsd.sig.ocn.mgh --cwpvalthresh 
.09 --seg cvs_avg35 aseg.mgz --csdpdf 
GroupAnalysis_pos.glmdir/contrast/permcsd.pdf.dat --csd 
GroupAnalysis_pos.glmdir/csd/permcsd.j001-contrast.csd --vwsig 
GroupAnalysis_pos.glmdir/contrast/permcsd.sig.voxel.mgh


and


mri_segstats --seg  permcsd.sig.ocn.mgh  --exclude 0 --i 
/media/2Tra/Antonella_2011/DTI_FS/GLM_CVS/GroupAnalysis-FA-MASKED.ANAT+CVS-to-avg35.nii.gz 
--avgwf fa.avg.dat --sum permcsd.sig.cluster.summary



Thank you.
Antonella
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Re: [Freesurfer] Clusters locations

2012-02-14 Thread Douglas N Greve


Antonella Kis wrote:
 Hi Doug,

 1) I would like to report the MNI coordinates and also a more exactly 
 region I mean if possible tto find exactly where in the 
 Left-Cerebral-White-Matter and Right-Cerebral-White-Matter my cluster 
 is located.
What do you me by exactly where? The nearest cortical label? The fiber 
bundle?

 2)Can you please tell me if for the mean diffusivity I should use the 
 simulation with the perm (as I use for the FA due to the fact that is 
 not so Gaussian) option  or it is OK to use the grf option.
I think you can use GRF for this as it corresponds to a normal contrast 
in a GLM. Note that the permutation is the stronger (but more 
conservative) test.


 3) Can you please explain what exactly means for my clusters if I hit 
 the positive sign under DISPLAY in Qdec? I mean if I compare the 
 cortical thickness between two classes: controls vs. Patients and
 I am not interested in the sex or age differences just differences 
 between the two classes will positive mean clusters where cortical 
 thickness graeter in Class 1 than Class2 (Class1Class2)?

 I have C = +1 -1 and my Class 1 = controls while Class2 = PAtients.
Positive is Controls  Patients

doug


 THANKS YOU.
 Antonella
 
 *From:* Douglas Greve gr...@nmr.mgh.harvard.edu
 *To:* Antonella Kis ator...@yahoo.com; free surfer 
 freesurfer@nmr.mgh.harvard.edu
 *Sent:* Tuesday, February 14, 2012 9:59 AM
 *Subject:* Re: [Freesurfer] Clusters locations

 Hi Antonella, what level of detail do you want? I think that most 
 people are reporting MNI coordinates.
 doug

 On 2/13/12 2:44 PM, Antonella Kis wrote:
 Hi Doug,

 I will be very grateful if you give me some directions regarding how 
 I can get my clusters location ( my output is too general telling me 
 just Left-Cerebral-White-Matter and Right-Cerebral-White-Matter) and 
 the coordinates (MNI) when I run the:

 mri_volcluster --in GroupAnalysis_pos.glmdir/contrast/sig.mgh --mask 
 GroupAnalysis_pos.glmdir/mask.mgh --no-fixmni --cwsig 
 GroupAnalysis_pos.glmdir/contrast/permcsd.sig.cluster.mgh --sum 
 GroupAnalysis_pos.glmdir/contrast/permcsd.sig.cluster.summary --ocn 
 GroupAnalysis_pos.glmdir/contrast/permcsd.sig.ocn.mgh --cwpvalthresh 
 .09 --seg cvs_avg35 aseg.mgz --csdpdf 
 GroupAnalysis_pos.glmdir/contrast/permcsd.pdf.dat --csd 
 GroupAnalysis_pos.glmdir/csd/permcsd.j001-contrast.csd --vwsig 
 GroupAnalysis_pos.glmdir/contrast/permcsd.sig.voxel.mgh

 and


 mri_segstats --seg  permcsd.sig.ocn.mgh  --exclude 0 --i 
 /media/2Tra/Antonella_2011/DTI_FS/GLM_CVS/GroupAnalysis-FA-MASKED.ANAT+CVS-to-avg35.nii.gz
  
 --avgwf fa.avg.dat --sum permcsd.sig.cluster.summary


 Thank you.
 Antonella

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 The information in this e-mail is intended only for the person to whom 
 it is
 addressed. If you believe this e-mail was sent to you in error and the 
 e-mail
 contains patient information, please contact the Partners Compliance 
 HelpLine at
 http://www.partners.org/complianceline . If the e-mail was sent to you 
 in error
 but does not contain patient information, please contact the sender 
 and properly
 dispose of the e-mail.



-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

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