Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread John Anderson
Dear Jürgen

This really helps!

I highly appreciate your input on this.

 

Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419

 
 

Sent: Monday, October 19, 2015 at 1:30 AM
From: JuergenHaenggi <j.haen...@psychologie.uzh.ch>
To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] MPRAGE SNR


Dear John
 

FS's QA tools provide the SNR 

see https://surfer.nmr.mgh.harvard.edu/fswiki/QATools

 

there is also a FS function called wm-anat-snr that can be used for that.

 

Hope this helps

Cheers

Jürgen


 

-
Jürgen Hänggi, Ph.D.
Division of Neuropsychology
Institute of Psychology
University of Zurich
Binzmuehlestrasse 14, PO Box 25 
8050 Zurich, Switzerland
0041 44 635 73 97 (phone office)
0041 76 445 86 84 (phone mobile)       
0041 44 635 74 09 (fax office)
BIN 4.D.04 (office room number)                     
j.haen...@psychologie.uzh.ch (email)
http://www.psychologie.uzh.ch/neuropsy/ (website)
http://www.juergenhaenggi.ch (private website)   

This e-mail (and any attachment/s) contains confidential and/or privileged
information. If you are not the intended recipient (or have received this
e-mail in error) please notify the sender immediately and destroy this
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-


 

 


Am 18.10.2015 um 16:48 schrieb John Anderson:
 




Dear Experts,

Is there any tool in Freesurfer that can help to evaluate the SNR for T1 MPRAGE images directly ( i.e script). If not knidly can any help me to figure out the best way to dao it.

 

I highly appreciate your help!

 

Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419


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Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread Bruce Fischl

Hi John

there is also a binary called mri_cnr that will compute the 
contrast-to-noise ratio (CNR), which is really the more interesting 
metric. It will also spit out the WM means+- std, and the ratio of these 
two can be used as an SNR measure.


cheers
Bruce


On Mon, 19 Oct 2015, John Anderson wrote:


Dear Jürgen
This really helps!
I highly appreciate your input on this.
 
Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
    Sent: Monday, October 19, 2015 at 1:30 AM
From: JuergenHaenggi <j.haen...@psychologie.uzh.ch>
To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] MPRAGE SNR
Dear John  
FS's QA tools provide the SNR 
see https://surfer.nmr.mgh.harvard.edu/fswiki/QATools
 
there is also a FS function called wm-anat-snr that can be used for that.
 
Hope this helps
Cheers
Jürgen
 
---
--
Jürgen Hänggi, Ph.D.
Division of Neuropsychology
Institute of Psychology
University of Zurich
Binzmuehlestrasse 14, PO Box 25 
8050 Zurich, Switzerland
0041 44 635 73 97 (phone office)
0041 76 445 86 84 (phone mobile)       
0041 44 635 74 09 (fax office)
BIN 4.D.04 (office room number)                     
j.haen...@psychologie.uzh.ch (email)
http://www.psychologie.uzh.ch/neuropsy/ (website)
http://www.juergenhaenggi.ch (private website)   

This e-mail (and any attachment/s) contains confidential and/or privileged
information. If you are not the intended recipient (or have received this
e-mail in error) please notify the sender immediately and destroy this
e-mail. Any unauthorised copying, disclosure or distribution of the
material in this e-mail is strictly forbidden.
---
--


 
  Am 18.10.2015 um 16:48 schrieb John Anderson:
 
  Dear Experts,
Is there any tool in Freesurfer that can help to evaluate the SNR for
T1 MPRAGE images directly ( i.e script). If not knidly can any help me
to figure out the best way to dao it.
 
I highly appreciate your help!
 
Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
___
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The information in this e-mail is intended only for the person to whom
it is
addressed. If you believe this e-mail was sent to you in error and the
e-mail
contains patient information, please contact the Partners Compliance
HelpLine at
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in error
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and properly
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___ Freesurfer mailing list
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patient information, please contact the Partners Compliance HelpLine at
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Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread Bruce Fischl
probably similar, although maybe Doug can comment. You probably want to run 
it on the orig.mgz as the intensity normalization can artificially increase 
the SNR (which is kind of the point)

Bruce


On Mon, 19 Oct 2015, John 
Anderson wrote:



Hi Bruce,
Thanks a lot!! this is really great!
I ran the command as the following :
 
mri_cnr subj_01/surf subj_01/mri/norm.mgz
processing MRI volume subj_01/mri/norm.mgz...
    white = 97.2+-9.5, gray = 69.0+-16.1, csf = 47.8+-16.5
    gray/white CNR = 2.291, gray/csf CNR = 0.848
lh CNR = 1.569
    white = 97.2+-9.3, gray = 69.4+-15.9, csf = 48.6+-17.0
    gray/white CNR = 2.278, gray/csf CNR = 0.798
rh CNR = 1.538
total CNR = 1.554
 
 
I noticed that the normal range for the SNR  (15-20) when using the command
"wm-anat-snr"
 
What is the normal range for cnr generated by the binary "mri_cnr"?
 
 
Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
    Sent: Monday, October 19, 2015 at 8:36 AM
From: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
Cc: j.haen...@psychologie.uzh.ch
Subject: Re: [Freesurfer] MPRAGE SNR
Hi John

there is also a binary called mri_cnr that will compute the
contrast-to-noise ratio (CNR), which is really the more interesting
metric. It will also spit out the WM means+- std, and the ratio of these
two can be used as an SNR measure.

cheers
Bruce


On Mon, 19 Oct 2015, John Anderson wrote:

> Dear Jürgen
> This really helps!
> I highly appreciate your input on this.
>  
> Bests,
> John Anderson
>
> Senior Research Associate
> Psychological and Brain Sciences Dept.
> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
> Phone: +1 (603) 646-9834
> Fax: +1 (603) 646-1419
>     Sent: Monday, October 19, 2015 at 1:30 AM
> From: JuergenHaenggi <j.haen...@psychologie.uzh.ch>
> To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
> Subject: Re: [Freesurfer] MPRAGE SNR
> Dear John  
> FS's QA tools provide the SNR 
> see https://surfer.nmr.mgh.harvard.edu/fswiki/QATools
>  
> there is also a FS function called wm-anat-snr that can be used for that.
>  
> Hope this helps
> Cheers
> Jürgen
>  
>---

> --
> Jürgen Hänggi, Ph.D.
> Division of Neuropsychology
> Institute of Psychology
> University of Zurich
> Binzmuehlestrasse 14, PO Box 25 
> 8050 Zurich, Switzerland
> 0041 44 635 73 97 (phone office)
> 0041 76 445 86 84 (phone mobile)       
> 0041 44 635 74 09 (fax office)
> BIN 4.D.04 (office room number)                     
> j.haen...@psychologie.uzh.ch (email)
> http://www.psychologie.uzh.ch/neuropsy/ (website)
> http://www.juergenhaenggi.ch (private website)   
>
> This e-mail (and any attachment/s) contains confidential and/or privileged
> information. If you are not the intended recipient (or have received this
> e-mail in error) please notify the sender immediately and destroy this
> e-mail. Any unauthorised copying, disclosure or distribution of the
> material in this e-mail is strictly forbidden.
>---

> --
>
>
>  
>   Am 18.10.2015 um 16:48 schrieb John Anderson:
>  
> Dear Experts,
> Is there any tool in Freesurfer that can help to evaluate the SNR for
> T1 MPRAGE images directly ( i.e script). If not knidly can any help me
> to figure out the best way to dao it.
>  
> I highly appreciate your help!
>  
> Bests,
> John Anderson
>
> Senior Research Associate
> Psychological and Brain Sciences Dept.
> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
> Phone: +1 (603) 646-9834
> Fax: +1 (603) 646-1419
> ___
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
>
> The information in this e-mail is intended only for the person to whom
> it is
> addressed. If you believe this e-mail was sent to you in error and the
> e-mail
> contains patient information, please contact the Partners Compliance
> HelpLine at
> http://www.partners.org/complianceline . If the e-mail was sent to you
> in error
> but does not contain patient information, please contact the sender
> and properly
> dispose of the e-mail.
>
> ___ Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/l

Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread Harms, Michael

Hi,

FWIW, I've looked at a number of these measures in 500+ subjects from HCP
data -- wm-anat-snr, pctsurfcon, G/W cnr, G/CSF cnr -- to see how they
relate to each other, and whether they correlate with mean cortical
thickness, white matter surface area, or number of SurfaceHoles (prior to
topology correction).

I didn't find much of note.  e.g., the highest correlations were:

r = -0.32 between mean cortical thickness and G/CSF cnr (from norm.mgz)
r = -0.25 between white surface area and wmanatsnr
r = -0.39 between SurfaceHoles and pctsurfcon (and same with G/W cnr from
norm.mgz)

Not surprisingly, pctsurfcon and G/W cnr are reasonably correlated (r =
0.49).

G/W cnr from norm.mgz and orig.mgz are correlated at r=0.80.
G/CSF cnr from norm.mgz and orig.mgz are correlated at r=0.97

In another context (but smaller number of subjects), I've looked to see if
these various snr, cnr measures from FS were related to manual quality
ratings, and the relationship was rather weak.

All-in-all, I haven't seen much that would indicate that these measures
can be used as a sort of "automated" QC measure.  Manual review of the
structurals and FS results is still needed.

That said, the structurals from the HCP 500 release were all of reasonably
good quality to begin with.  So, it is possible that these snr/cnr
measures might be more informative in identifying truly awful scans in a
clinical population with a wider variability in MPRAGE scan quality.

I'd certainly be interested in hearing from anyone if they have found that
to be the case in their data.

BTW: Average value for G/W cnr for the HCP 500 is 1.99 and 1.81 from
orig.mgz and norm.mgz respectively.
Average value for G/CSF cnr for the same is 0.78 and 0.79, respectively.

cheers,
-MH

--
Michael Harms, Ph.D.

---
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave.Tel: 314-747-6173
St. Louis, MO  63110Email: mha...@wustl.edu




On 10/19/15 8:09 AM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:

probably similar, although maybe Doug can comment. You probably want to
run
it on the orig.mgz as the intensity normalization can artificially
increase
the SNR (which is kind of the point)
Bruce


On Mon, 19 Oct 2015, John
Anderson wrote:

> Hi Bruce,
> Thanks a lot!! this is really great!
> I ran the command as the following :
>
> mri_cnr subj_01/surf subj_01/mri/norm.mgz
> processing MRI volume subj_01/mri/norm.mgz...
> white = 97.2+-9.5, gray = 69.0+-16.1, csf = 47.8+-16.5
> gray/white CNR = 2.291, gray/csf CNR = 0.848
> lh CNR = 1.569
> white = 97.2+-9.3, gray = 69.4+-15.9, csf = 48.6+-17.0
> gray/white CNR = 2.278, gray/csf CNR = 0.798
> rh CNR = 1.538
> total CNR = 1.554
>
>
> I noticed that the normal range for the SNR  (15-20) when using the
>command
> "wm-anat-snr"
>
> What is the normal range for cnr generated by the binary "mri_cnr"?
>
>
> Bests,
> John Anderson
>
> Senior Research Associate
> Psychological and Brain Sciences Dept.
> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
> Phone: +1 (603) 646-9834
> Fax: +1 (603) 646-1419
> Sent: Monday, October 19, 2015 at 8:36 AM
> From: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
> To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
> Cc: j.haen...@psychologie.uzh.ch
> Subject: Re: [Freesurfer] MPRAGE SNR
> Hi John
>
> there is also a binary called mri_cnr that will compute the
> contrast-to-noise ratio (CNR), which is really the more interesting
> metric. It will also spit out the WM means+- std, and the ratio of these
> two can be used as an SNR measure.
>
> cheers
> Bruce
>
>
> On Mon, 19 Oct 2015, John Anderson wrote:
>
> > Dear Jürgen
> > This really helps!
> > I highly appreciate your input on this.
> >
> > Bests,
> > John Anderson
> >
> > Senior Research Associate
> > Psychological and Brain Sciences Dept.
> > Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
> > Phone: +1 (603) 646-9834
> > Fax: +1 (603) 646-1419
> > Sent: Monday, October 19, 2015 at 1:30 AM
> > From: JuergenHaenggi <j.haen...@psychologie.uzh.ch>
> > To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
> > Subject: Re: [Freesurfer] MPRAGE SNR
> > Dear John
> > FS's QA tools provide the SNR
> > see https://surfer.nmr.mgh.harvard.edu/fswiki/QATools
> >
> > there is also a FS function called wm-anat-snr that can be used for
>that.
> >
> > Hope this helps
> > Cheers
> > Jürgen
> >
>
>>--

Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread Matt Glasser
There is also the issue that grey and white matter are not truly a
homogeneous single intensity anatomically.

Peace,

Matt.

On 10/19/15, 9:23 AM, "Harms, Michael"
<freesurfer-boun...@nmr.mgh.harvard.edu on behalf of mha...@wustl.edu>
wrote:

>
>Hi,
>
>FWIW, I've looked at a number of these measures in 500+ subjects from HCP
>data -- wm-anat-snr, pctsurfcon, G/W cnr, G/CSF cnr -- to see how they
>relate to each other, and whether they correlate with mean cortical
>thickness, white matter surface area, or number of SurfaceHoles (prior to
>topology correction).
>
>I didn't find much of note.  e.g., the highest correlations were:
>
>r = -0.32 between mean cortical thickness and G/CSF cnr (from norm.mgz)
>r = -0.25 between white surface area and wmanatsnr
>r = -0.39 between SurfaceHoles and pctsurfcon (and same with G/W cnr from
>norm.mgz)
>
>Not surprisingly, pctsurfcon and G/W cnr are reasonably correlated (r =
>0.49).
>
>G/W cnr from norm.mgz and orig.mgz are correlated at r=0.80.
>G/CSF cnr from norm.mgz and orig.mgz are correlated at r=0.97
>
>In another context (but smaller number of subjects), I've looked to see if
>these various snr, cnr measures from FS were related to manual quality
>ratings, and the relationship was rather weak.
>
>All-in-all, I haven't seen much that would indicate that these measures
>can be used as a sort of "automated" QC measure.  Manual review of the
>structurals and FS results is still needed.
>
>That said, the structurals from the HCP 500 release were all of reasonably
>good quality to begin with.  So, it is possible that these snr/cnr
>measures might be more informative in identifying truly awful scans in a
>clinical population with a wider variability in MPRAGE scan quality.
>
>I'd certainly be interested in hearing from anyone if they have found that
>to be the case in their data.
>
>BTW: Average value for G/W cnr for the HCP 500 is 1.99 and 1.81 from
>orig.mgz and norm.mgz respectively.
>Average value for G/CSF cnr for the same is 0.78 and 0.79, respectively.
>
>cheers,
>-MH
>
>--
>Michael Harms, Ph.D.
>
>---
>Conte Center for the Neuroscience of Mental Disorders
>Washington University School of Medicine
>Department of Psychiatry, Box 8134
>660 South Euclid Ave.Tel: 314-747-6173
>St. Louis, MO  63110Email: mha...@wustl.edu
>
>
>
>
>On 10/19/15 8:09 AM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
>
>probably similar, although maybe Doug can comment. You probably want to
>run
>it on the orig.mgz as the intensity normalization can artificially
>increase
>the SNR (which is kind of the point)
>Bruce
>
>
>On Mon, 19 Oct 2015, John
>Anderson wrote:
>
>> Hi Bruce,
>> Thanks a lot!! this is really great!
>> I ran the command as the following :
>>
>> mri_cnr subj_01/surf subj_01/mri/norm.mgz
>> processing MRI volume subj_01/mri/norm.mgz...
>> white = 97.2+-9.5, gray = 69.0+-16.1, csf = 47.8+-16.5
>> gray/white CNR = 2.291, gray/csf CNR = 0.848
>> lh CNR = 1.569
>> white = 97.2+-9.3, gray = 69.4+-15.9, csf = 48.6+-17.0
>> gray/white CNR = 2.278, gray/csf CNR = 0.798
>> rh CNR = 1.538
>> total CNR = 1.554
>>
>>
>> I noticed that the normal range for the SNR  (15-20) when using the
>>command
>> "wm-anat-snr"
>>
>> What is the normal range for cnr generated by the binary "mri_cnr"?
>>
>>
>> Bests,
>> John Anderson
>>
>> Senior Research Associate
>> Psychological and Brain Sciences Dept.
>> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
>> Phone: +1 (603) 646-9834
>> Fax: +1 (603) 646-1419
>> Sent: Monday, October 19, 2015 at 8:36 AM
>> From: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
>> To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
>> Cc: j.haen...@psychologie.uzh.ch
>> Subject: Re: [Freesurfer] MPRAGE SNR
>> Hi John
>>
>> there is also a binary called mri_cnr that will compute the
>> contrast-to-noise ratio (CNR), which is really the more interesting
>> metric. It will also spit out the WM means+- std, and the ratio of these
>> two can be used as an SNR measure.
>>
>> cheers
>> Bruce
>>
>>
>> On Mon, 19 Oct 2015, John Anderson wrote:
>>
>> > Dear Jürgen
>> > This really helps!
>> > I highly appreciate your input on this.
>> >
>> > Bests,
>> > John Anderson
>> >
>> >

Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread Douglas Greve
This has been my experience as well. Not much seems to predict which 
scans will need to be edited.

On 10/19/15 10:23 AM, Harms, Michael wrote:
> Hi,
>
> FWIW, I've looked at a number of these measures in 500+ subjects from HCP
> data -- wm-anat-snr, pctsurfcon, G/W cnr, G/CSF cnr -- to see how they
> relate to each other, and whether they correlate with mean cortical
> thickness, white matter surface area, or number of SurfaceHoles (prior to
> topology correction).
>
> I didn't find much of note.  e.g., the highest correlations were:
>
> r = -0.32 between mean cortical thickness and G/CSF cnr (from norm.mgz)
> r = -0.25 between white surface area and wmanatsnr
> r = -0.39 between SurfaceHoles and pctsurfcon (and same with G/W cnr from
> norm.mgz)
>
> Not surprisingly, pctsurfcon and G/W cnr are reasonably correlated (r =
> 0.49).
>
> G/W cnr from norm.mgz and orig.mgz are correlated at r=0.80.
> G/CSF cnr from norm.mgz and orig.mgz are correlated at r=0.97
>
> In another context (but smaller number of subjects), I've looked to see if
> these various snr, cnr measures from FS were related to manual quality
> ratings, and the relationship was rather weak.
>
> All-in-all, I haven't seen much that would indicate that these measures
> can be used as a sort of "automated" QC measure.  Manual review of the
> structurals and FS results is still needed.
>
> That said, the structurals from the HCP 500 release were all of reasonably
> good quality to begin with.  So, it is possible that these snr/cnr
> measures might be more informative in identifying truly awful scans in a
> clinical population with a wider variability in MPRAGE scan quality.
>
> I'd certainly be interested in hearing from anyone if they have found that
> to be the case in their data.
>
> BTW: Average value for G/W cnr for the HCP 500 is 1.99 and 1.81 from
> orig.mgz and norm.mgz respectively.
> Average value for G/CSF cnr for the same is 0.78 and 0.79, respectively.
>
> cheers,
> -MH
>
> --
> Michael Harms, Ph.D.
>
> ---
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 8134
> 660 South Euclid Ave.Tel: 314-747-6173
> St. Louis, MO  63110Email: mha...@wustl.edu
>
>
>
>
> On 10/19/15 8:09 AM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
>
> probably similar, although maybe Doug can comment. You probably want to
> run
> it on the orig.mgz as the intensity normalization can artificially
> increase
> the SNR (which is kind of the point)
> Bruce
>
>
> On Mon, 19 Oct 2015, John
> Anderson wrote:
>
>> Hi Bruce,
>> Thanks a lot!! this is really great!
>> I ran the command as the following :
>>
>> mri_cnr subj_01/surf subj_01/mri/norm.mgz
>> processing MRI volume subj_01/mri/norm.mgz...
>>  white = 97.2+-9.5, gray = 69.0+-16.1, csf = 47.8+-16.5
>>  gray/white CNR = 2.291, gray/csf CNR = 0.848
>> lh CNR = 1.569
>>  white = 97.2+-9.3, gray = 69.4+-15.9, csf = 48.6+-17.0
>>  gray/white CNR = 2.278, gray/csf CNR = 0.798
>> rh CNR = 1.538
>> total CNR = 1.554
>>
>>
>> I noticed that the normal range for the SNR  (15-20) when using the
>> command
>> "wm-anat-snr"
>>
>> What is the normal range for cnr generated by the binary "mri_cnr"?
>>
>>
>> Bests,
>> John Anderson
>>
>> Senior Research Associate
>> Psychological and Brain Sciences Dept.
>> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
>> Phone: +1 (603) 646-9834
>> Fax: +1 (603) 646-1419
>>  Sent: Monday, October 19, 2015 at 8:36 AM
>> From: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
>> To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
>> Cc: j.haen...@psychologie.uzh.ch
>> Subject: Re: [Freesurfer] MPRAGE SNR
>> Hi John
>>
>> there is also a binary called mri_cnr that will compute the
>> contrast-to-noise ratio (CNR), which is really the more interesting
>> metric. It will also spit out the WM means+- std, and the ratio of these
>> two can be used as an SNR measure.
>>
>> cheers
>> Bruce
>>
>>
>> On Mon, 19 Oct 2015, John Anderson wrote:
>>
>>> Dear Jürgen
>>> This really helps!
>>> I highly appreciate your input on this.
>>>
>>> Bests,
>>> John Anderson
>>>
>>>

Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread John Anderson
Hi All,

Thank you very much for your comments!

 

Is it advisable to include SNR as a covariate when we use Qdec to run the final statistics on volumetrics, surfaces and cortical thickness?

Does it make sence ?

 

Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419

 
 

Sent: Monday, October 19, 2015 at 11:48 AM
From: "Douglas Greve" <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] MPRAGE SNR

This has been my experience as well. Not much seems to predict which
scans will need to be edited.

On 10/19/15 10:23 AM, Harms, Michael wrote:
> Hi,
>
> FWIW, I've looked at a number of these measures in 500+ subjects from HCP
> data -- wm-anat-snr, pctsurfcon, G/W cnr, G/CSF cnr -- to see how they
> relate to each other, and whether they correlate with mean cortical
> thickness, white matter surface area, or number of SurfaceHoles (prior to
> topology correction).
>
> I didn't find much of note. e.g., the highest correlations were:
>
> r = -0.32 between mean cortical thickness and G/CSF cnr (from norm.mgz)
> r = -0.25 between white surface area and wmanatsnr
> r = -0.39 between SurfaceHoles and pctsurfcon (and same with G/W cnr from
> norm.mgz)
>
> Not surprisingly, pctsurfcon and G/W cnr are reasonably correlated (r =
> 0.49).
>
> G/W cnr from norm.mgz and orig.mgz are correlated at r=0.80.
> G/CSF cnr from norm.mgz and orig.mgz are correlated at r=0.97
>
> In another context (but smaller number of subjects), I've looked to see if
> these various snr, cnr measures from FS were related to manual quality
> ratings, and the relationship was rather weak.
>
> All-in-all, I haven't seen much that would indicate that these measures
> can be used as a sort of "automated" QC measure. Manual review of the
> structurals and FS results is still needed.
>
> That said, the structurals from the HCP 500 release were all of reasonably
> good quality to begin with. So, it is possible that these snr/cnr
> measures might be more informative in identifying truly awful scans in a
> clinical population with a wider variability in MPRAGE scan quality.
>
> I'd certainly be interested in hearing from anyone if they have found that
> to be the case in their data.
>
> BTW: Average value for G/W cnr for the HCP 500 is 1.99 and 1.81 from
> orig.mgz and norm.mgz respectively.
> Average value for G/CSF cnr for the same is 0.78 and 0.79, respectively.
>
> cheers,
> -MH
>
> --
> Michael Harms, Ph.D.
>
> ---
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 8134
> 660 South Euclid Ave.Tel: 314-747-6173
> St. Louis, MO 63110Email: mha...@wustl.edu
>
>
>
>
> On 10/19/15 8:09 AM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
>
> probably similar, although maybe Doug can comment. You probably want to
> run
> it on the orig.mgz as the intensity normalization can artificially
> increase
> the SNR (which is kind of the point)
> Bruce
>
>
> On Mon, 19 Oct 2015, John
> Anderson wrote:
>
>> Hi Bruce,
>> Thanks a lot!! this is really great!
>> I ran the command as the following :
>>
>> mri_cnr subj_01/surf subj_01/mri/norm.mgz
>> processing MRI volume subj_01/mri/norm.mgz...
>> white = 97.2+-9.5, gray = 69.0+-16.1, csf = 47.8+-16.5
>> gray/white CNR = 2.291, gray/csf CNR = 0.848
>> lh CNR = 1.569
>> white = 97.2+-9.3, gray = 69.4+-15.9, csf = 48.6+-17.0
>> gray/white CNR = 2.278, gray/csf CNR = 0.798
>> rh CNR = 1.538
>> total CNR = 1.554
>>
>>
>> I noticed that the normal range for the SNR (15-20) when using the
>> command
>> "wm-anat-snr"
>>
>> What is the normal range for cnr generated by the binary "mri_cnr"?
>>
>>
>> Bests,
>> John Anderson
>>
>> Senior Research Associate
>> Psychological and Brain Sciences Dept.
>> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
>> Phone: +1 (603) 646-9834
>> Fax: +1 (603) 646-1419
>> Sent: Monday, October 19, 2015 at 8:36 AM
>> From: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
>> To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
>> Cc: j.haen...@psychologie.uzh.ch
>> Subject: Re: [Freesurfer] MPRAGE SNR
>> Hi John
>>
>> there is also a binary called mri_cnr that will compute the
>> contrast-to-noise ratio (CNR), which 

Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread Bruce Fischl

I think you would just be wasting your power
Bruce
On Mon, 19 Oct 2015, John 
Anderson wrote:



Hi All,
Thank you very much for your comments!
 
Is it advisable to include SNR as a covariate when we use Qdec to run the
final statistics on volumetrics, surfaces and cortical thickness?
Does it make sence ?
 
Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
    Sent: Monday, October 19, 2015 at 11:48 AM
From: "Douglas Greve" <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] MPRAGE SNR
This has been my experience as well. Not much seems to predict which
scans will need to be edited.

On 10/19/15 10:23 AM, Harms, Michael wrote:
> Hi,
>
> FWIW, I've looked at a number of these measures in 500+ subjects from HCP
> data -- wm-anat-snr, pctsurfcon, G/W cnr, G/CSF cnr -- to see how they
> relate to each other, and whether they correlate with mean cortical
> thickness, white matter surface area, or number of SurfaceHoles (prior to
> topology correction).
>
> I didn't find much of note. e.g., the highest correlations were:
>
> r = -0.32 between mean cortical thickness and G/CSF cnr (from norm.mgz)
> r = -0.25 between white surface area and wmanatsnr
> r = -0.39 between SurfaceHoles and pctsurfcon (and same with G/W cnr from
> norm.mgz)
>
> Not surprisingly, pctsurfcon and G/W cnr are reasonably correlated (r =
> 0.49).
>
> G/W cnr from norm.mgz and orig.mgz are correlated at r=0.80.
> G/CSF cnr from norm.mgz and orig.mgz are correlated at r=0.97
>
> In another context (but smaller number of subjects), I've looked to see if
> these various snr, cnr measures from FS were related to manual quality
> ratings, and the relationship was rather weak.
>
> All-in-all, I haven't seen much that would indicate that these measures
> can be used as a sort of "automated" QC measure. Manual review of the
> structurals and FS results is still needed.
>
> That said, the structurals from the HCP 500 release were all of reasonably
> good quality to begin with. So, it is possible that these snr/cnr
> measures might be more informative in identifying truly awful scans in a
> clinical population with a wider variability in MPRAGE scan quality.
>
> I'd certainly be interested in hearing from anyone if they have found that
> to be the case in their data.
>
> BTW: Average value for G/W cnr for the HCP 500 is 1.99 and 1.81 from
> orig.mgz and norm.mgz respectively.
> Average value for G/CSF cnr for the same is 0.78 and 0.79, respectively.
>
> cheers,
> -MH
>
> --
> Michael Harms, Ph.D.
>
> ---
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 8134
> 660 South Euclid Ave.Tel: 314-747-6173
> St. Louis, MO 63110Email: mha...@wustl.edu
>
>
>
>
> On 10/19/15 8:09 AM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
>
> probably similar, although maybe Doug can comment. You probably want to
> run
> it on the orig.mgz as the intensity normalization can artificially
> increase
> the SNR (which is kind of the point)
> Bruce
>
>
> On Mon, 19 Oct 2015, John
> Anderson wrote:
>
>> Hi Bruce,
>> Thanks a lot!! this is really great!
>> I ran the command as the following :
>>
>> mri_cnr subj_01/surf subj_01/mri/norm.mgz
>> processing MRI volume subj_01/mri/norm.mgz...
>> white = 97.2+-9.5, gray = 69.0+-16.1, csf = 47.8+-16.5
>> gray/white CNR = 2.291, gray/csf CNR = 0.848
>> lh CNR = 1.569
>> white = 97.2+-9.3, gray = 69.4+-15.9, csf = 48.6+-17.0
>> gray/white CNR = 2.278, gray/csf CNR = 0.798
>> rh CNR = 1.538
>> total CNR = 1.554
>>
>>
>> I noticed that the normal range for the SNR (15-20) when using the
>> command
>> "wm-anat-snr"
>>
>> What is the normal range for cnr generated by the binary "mri_cnr"?
>>
>>
>> Bests,
>> John Anderson
>>
>> Senior Research Associate
>> Psychological and Brain Sciences Dept.
>> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
>> Phone: +1 (603) 646-9834
>> Fax: +1 (603) 646-1419
>> Sent: Monday, October 19, 2015 at 8:36 AM
>> From: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
>> To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
>> Cc: j.haen...@psychologie.uzh.ch
>> Subject: Re: [Freesurfer] MPRAGE SNR
>> Hi John
>>
>> there is also a bin

Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread Harms, Michael







My experience, which appears to be consistent with Doug's, is that there is no substitute for reviewing the images and FS results manually.  Ultimately, it is a bit of a judgement call, and interacts with the goals/purposes of your study.




-- 
Michael Harms, Ph.D.

---
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave. 
Tel: 314-747-6173
St. Louis, MO  63110 
Email: mha...@wustl.edu







From: John Anderson <j.ander...@publicist.com>
Reply-To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, October 19, 2015 11:30 AM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Cc: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] MPRAGE SNR






Thanks MH,
Let's say that we have 100 MPRAGEs and we want to include them in a cross sectional analysis.
Depending on your experience, do you recommend any criterion to (include/ exclude) these images  in the analysis? As I see visualizing the images alone is not enough to say that the quality of the image is fine. Also calculating the SNR, CNR want help
 a lot!
 
any suggestions?
 
Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
 
 

Sent: Monday, October 19, 2015 at 12:24 PM
From: "Harms, Michael" <mha...@wustl.edu>
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] MPRAGE SNR



 
At best that would probably be harmless (if you have a decent number of subjects), but unless SNR, CNR actually relates to those measures in some fashion, you aren't really accomplishing anything by including it as a covariate.  You certainly wouldn't
 be able to claim that including SNR as a covariate has somehow "controlled" for MPRAGE data quality because there doesn't appear to be much of a relationship in the first place.
 
cheers,
-MH
 


-- 
Michael Harms, Ph.D.

---
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave.Tel: 314-747-6173
St. Louis, MO  63110 
Email: mha...@wustl.edu


 

From: John Anderson <j.ander...@publicist.com>
Reply-To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, October 19, 2015 10:57 AM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Cc: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] MPRAGE SNR
 



Hi All,
Thank you very much for your comments!
 
Is it advisable to include SNR as a covariate when we use Qdec to run the final statistics on volumetrics, surfaces and cortical thickness?
Does it make sence ?
 
Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
  
  

Sent: Monday, October 19, 2015 at 11:48 AM
From: "Douglas Greve" <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] MPRAGE SNR
This has been my experience as well. Not much seems to predict which
scans will need to be edited.

On 10/19/15 10:23 AM, Harms, Michael wrote:
> Hi,
>
> FWIW, I've looked at a number of these measures in 500+ subjects from HCP
> data -- wm-anat-snr, pctsurfcon, G/W cnr, G/CSF cnr -- to see how they
> relate to each other, and whether they correlate with mean cortical
> thickness, white matter surface area, or number of SurfaceHoles (prior to
> topology correction).
>
> I didn't find much of note. e.g., the highest correlations were:
>
> r = -0.32 between mean cortical thickness and G/CSF cnr (from norm.mgz)
> r = -0.25 between white surface area and wmanatsnr
> r = -0.39 between SurfaceHoles and pctsurfcon (and same with G/W cnr from
> norm.mgz)
>
> Not surprisingly, pctsurfcon and G/W cnr are reasonably correlated (r =
> 0.49).
>
> G/W cnr from norm.mgz and orig.mgz are correlated at r=0.80.
> G/CSF cnr from norm.mgz and orig.mgz are correlated at r=0.97
>
> In another context (but smaller number of subjects), I've looked to see if
> these various snr, cnr measures from FS were related to manual quality
> ratings, and the relationship was rather weak.
>
> All-in-all, I haven't seen much that would indicate that these measures
> can be used as a sort of "automated" QC measure. Manual review of the
> structurals and FS results 

Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread Harms, Michael






At best that would probably be harmless (if you have a decent number of subjects), but unless SNR, CNR actually relates to those measures in some fashion, you aren't really accomplishing anything by including it as a covariate.  You certainly wouldn't
 be able to claim that including SNR as a covariate has somehow "controlled" for MPRAGE data quality because there doesn't appear to be much of a relationship in the first place.


cheers,
-MH




-- 
Michael Harms, Ph.D.

---
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave. 
Tel: 314-747-6173
St. Louis, MO  63110 
Email: mha...@wustl.edu






From: John Anderson <j.ander...@publicist.com>
Reply-To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, October 19, 2015 10:57 AM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Cc: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] MPRAGE SNR






Hi All,
Thank you very much for your comments!
 
Is it advisable to include SNR as a covariate when we use Qdec to run the final statistics on volumetrics, surfaces and cortical thickness?
Does it make sence ?
 
Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
 
 

Sent: Monday, October 19, 2015 at 11:48 AM
From: "Douglas Greve" <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] MPRAGE SNR
This has been my experience as well. Not much seems to predict which
scans will need to be edited.

On 10/19/15 10:23 AM, Harms, Michael wrote:
> Hi,
>
> FWIW, I've looked at a number of these measures in 500+ subjects from HCP
> data -- wm-anat-snr, pctsurfcon, G/W cnr, G/CSF cnr -- to see how they
> relate to each other, and whether they correlate with mean cortical
> thickness, white matter surface area, or number of SurfaceHoles (prior to
> topology correction).
>
> I didn't find much of note. e.g., the highest correlations were:
>
> r = -0.32 between mean cortical thickness and G/CSF cnr (from norm.mgz)
> r = -0.25 between white surface area and wmanatsnr
> r = -0.39 between SurfaceHoles and pctsurfcon (and same with G/W cnr from
> norm.mgz)
>
> Not surprisingly, pctsurfcon and G/W cnr are reasonably correlated (r =
> 0.49).
>
> G/W cnr from norm.mgz and orig.mgz are correlated at r=0.80.
> G/CSF cnr from norm.mgz and orig.mgz are correlated at r=0.97
>
> In another context (but smaller number of subjects), I've looked to see if
> these various snr, cnr measures from FS were related to manual quality
> ratings, and the relationship was rather weak.
>
> All-in-all, I haven't seen much that would indicate that these measures
> can be used as a sort of "automated" QC measure. Manual review of the
> structurals and FS results is still needed.
>
> That said, the structurals from the HCP 500 release were all of reasonably
> good quality to begin with. So, it is possible that these snr/cnr
> measures might be more informative in identifying truly awful scans in a
> clinical population with a wider variability in MPRAGE scan quality.
>
> I'd certainly be interested in hearing from anyone if they have found that
> to be the case in their data.
>
> BTW: Average value for G/W cnr for the HCP 500 is 1.99 and 1.81 from
> orig.mgz and norm.mgz respectively.
> Average value for G/CSF cnr for the same is 0.78 and 0.79, respectively.
>
> cheers,
> -MH
>
> --
> Michael Harms, Ph.D.
>
> ---
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 8134
> 660 South Euclid Ave.Tel: 314-747-6173
> St. Louis, MO 63110Email: mha...@wustl.edu
>
>
>
>
> On 10/19/15 8:09 AM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
>
> probably similar, although maybe Doug can comment. You probably want to
> run
> it on the orig.mgz as the intensity normalization can artificially
> increase
> the SNR (which is kind of the point)
> Bruce
>
>
> On Mon, 19 Oct 2015, John
> Anderson wrote:
>
>> Hi Bruce,
>> Thanks a lot!! this is really great!
>> I ran the command as the following :
>>
>> mri_cnr subj_01/surf subj_01/mri/norm.mgz
>> processing MRI volume subj_01/mri/norm.mgz...
>> white = 97.2+-9.5, gray = 69.0+-16.1, csf = 47.8+-16.5
>> gray/white CNR = 2.291, gray/csf CNR = 0.848

Re: [Freesurfer] MPRAGE SNR

2015-10-19 Thread John Anderson
Thanks MH,

Let's say that we have 100 MPRAGEs and we want to include them in a cross sectional analysis.

Depending on your experience, do you recommend any criterion to (include/ exclude) these images  in the analysis? As I see visualizing the images alone is not enough to say that the quality of the image is fine. Also calculating the SNR, CNR want help a lot!

 

any suggestions?
 

Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419

 
 

Sent: Monday, October 19, 2015 at 12:24 PM
From: "Harms, Michael" <mha...@wustl.edu>
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] MPRAGE SNR




 

At best that would probably be harmless (if you have a decent number of subjects), but unless SNR, CNR actually relates to those measures in some fashion, you aren't really accomplishing anything by including it as a covariate.  You certainly wouldn't be able to claim that including SNR as a covariate has somehow "controlled" for MPRAGE data quality because there doesn't appear to be much of a relationship in the first place.

 

cheers,

-MH

 



-- 

Michael Harms, Ph.D.


---

Conte Center for the Neuroscience of Mental Disorders

Washington University School of Medicine

Department of Psychiatry, Box 8134

660 South Euclid Ave.  Tel: 314-747-6173

St. Louis, MO  63110  Email: mha...@wustl.edu



 

From: John Anderson <j.ander...@publicist.com>
Reply-To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, October 19, 2015 10:57 AM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Cc: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] MPRAGE SNR

 




Hi All,

Thank you very much for your comments!

 

Is it advisable to include SNR as a covariate when we use Qdec to run the final statistics on volumetrics, surfaces and cortical thickness?

Does it make sence ?

 

Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419

  

  


Sent: Monday, October 19, 2015 at 11:48 AM
From: "Douglas Greve" <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] MPRAGE SNR

This has been my experience as well. Not much seems to predict which
scans will need to be edited.

On 10/19/15 10:23 AM, Harms, Michael wrote:
> Hi,
>
> FWIW, I've looked at a number of these measures in 500+ subjects from HCP
> data -- wm-anat-snr, pctsurfcon, G/W cnr, G/CSF cnr -- to see how they
> relate to each other, and whether they correlate with mean cortical
> thickness, white matter surface area, or number of SurfaceHoles (prior to
> topology correction).
>
> I didn't find much of note. e.g., the highest correlations were:
>
> r = -0.32 between mean cortical thickness and G/CSF cnr (from norm.mgz)
> r = -0.25 between white surface area and wmanatsnr
> r = -0.39 between SurfaceHoles and pctsurfcon (and same with G/W cnr from
> norm.mgz)
>
> Not surprisingly, pctsurfcon and G/W cnr are reasonably correlated (r =
> 0.49).
>
> G/W cnr from norm.mgz and orig.mgz are correlated at r=0.80.
> G/CSF cnr from norm.mgz and orig.mgz are correlated at r=0.97
>
> In another context (but smaller number of subjects), I've looked to see if
> these various snr, cnr measures from FS were related to manual quality
> ratings, and the relationship was rather weak.
>
> All-in-all, I haven't seen much that would indicate that these measures
> can be used as a sort of "automated" QC measure. Manual review of the
> structurals and FS results is still needed.
>
> That said, the structurals from the HCP 500 release were all of reasonably
> good quality to begin with. So, it is possible that these snr/cnr
> measures might be more informative in identifying truly awful scans in a
> clinical population with a wider variability in MPRAGE scan quality.
>
> I'd certainly be interested in hearing from anyone if they have found that
> to be the case in their data.
>
> BTW: Average value for G/W cnr for the HCP 500 is 1.99 and 1.81 from
> orig.mgz and norm.mgz respectively.
> Average value for G/CSF cnr for the same is 0.78 and 0.79, respectively.
>
> cheers,
> -MH
>
> --
> Michael Harms, Ph.D.
>
> ---
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 

Re: [Freesurfer] MPRAGE SNR

2015-10-18 Thread JuergenHaenggi
Dear John

FS's QA tools provide the SNR 
see https://surfer.nmr.mgh.harvard.edu/fswiki/QATools

there is also a FS function called wm-anat-snr that can be used for that.

Hope this helps
Cheers
Jürgen


-
Jürgen Hänggi, Ph.D.
Division of Neuropsychology
Institute of Psychology
University of Zurich
Binzmuehlestrasse 14, PO Box 25 
8050 Zurich, Switzerland
0041 44 635 73 97 (phone office)
0041 76 445 86 84 (phone mobile)   
0041 44 635 74 09 (fax office)
BIN 4.D.04 (office room number) 
j.haen...@psychologie.uzh.ch (email)
http://www.psychologie.uzh.ch/neuropsy/ (website)
http://www.juergenhaenggi.ch (private website)   

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Am 18.10.2015 um 16:48 schrieb John Anderson:

> Dear Experts,
> Is there any tool in Freesurfer that can help to evaluate the SNR for T1 
> MPRAGE images directly ( i.e script). If not knidly can any help me to figure 
> out the best way to dao it.
>  
> I highly appreciate your help!
>  
> Bests,
> John Anderson
> 
> Senior Research Associate
> Psychological and Brain Sciences Dept.
> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
> Phone: +1 (603) 646-9834
> Fax: +1 (603) 646-1419
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