Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)
On 09/24/2015 11:16 AM, Parks, Raymond wrote: this time last year I had just been told I don't have lymphoma. Of course, what I have is, as usual, a disease of unknown origin with symptomatic treatment at best. There's a reason that what doctors do is called "practice". That's both better and worse, I imagine. It's when they _think_ they know what's happening that they get really dangerous. Interesting shift from idiographic to idiopathic! -- ⇔ glen FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)
Actually, the Futurama version reminds me more of Abby Normal - https://www.youtube.com/watch?v=yH97lImrr0Q Oh, and poor attempts at humour are my defense against bad news - this time about Glen. I can sympathize - this time last year I had just been told I don't have lymphoma. Of course, what I have is, as usual, a disease of unknown origin with symptomatic treatment at best. There's a reason that what doctors do is called "practice". Ray Parks Consilient Heuristician/IDART Old-Timer V: 505-844-4024 M: 505-238-9359 P: 505-951-6084 NIPR: rcpa...@sandia.gov SIPR: rcpar...@sandia.doe.sgov.gov (send NIPR reminder) JWICS: dopa...@doe.ic.gov (send NIPR reminder) On Sep 24, 2015, at 9:44 AM, Marcus Daniels wrote: > Right! > > http://alcor.org/AtWork/index.html > > -Original Message- > From: Friam [mailto:friam-boun...@redfish.com] On Behalf Of Parks, Raymond > Sent: Thursday, September 24, 2015 9:39 AM > To: 'friam@redfish.com' > Subject: Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue > into Chimerism and Epigenetics) > > It would be much more convenient to store your head in a jar, a la Futurama. > And more comedic. > > Ray Parks > > > > > - Original Message - > From: Marcus Daniels [mailto:mar...@snoutfarm.com] > Sent: Thursday, September 24, 2015 09:33 AM > To: The Friday Morning Applied Complexity Coffee Group > Subject: [EXTERNAL] Re: [FRIAM] I am Cancer, hear me roar! (with segue into > Chimerism and Epigenetics) > > Well, I assume that if my connectome could be scanned with sufficient > fidelity, and stored in a computer, that it would be possible, someday, to > both query my memories, but also to measure emotional responses, in silico. > Probably even start and stop consciousness.The trick would be figuring > out the interfaces, but obvious places to start would be the visual cortex, > auditory centers, and various incoming nerves.It could sort of be > approaches as a machine learning problem, like is beginning to be done with > replacement limbs. > > Sure there are aspects of my physical self that are slightly unique to me, > but I would expect they are modularized. The experience of running, typing, > and so on. But those things aren't me. If anything, it would seem to be > thrilling to experience other real or simulated nervous systems. > > Yes, I know, what huge waste of disk space! > Btw, what rights do the dead have to their own memories? A whole new field > of IP law! > > -Original Message- > From: Friam [mailto:friam-boun...@redfish.com] On Behalf Of Steve Smith > Sent: Thursday, September 24, 2015 9:22 AM > To: The Friday Morning Applied Complexity Coffee Group > Subject: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and > Epigenetics) > > Glen/Nick - >>> Having said that, am I allowed to say, "Crap! I wish you didn't have >>> cancer!' >> Of course. Thanks. But just to be argumentative, > ... >> I am cancer. It's probably not true of all cancers, though. > I recently had a long conversation with a Muslim friend from Australia who > donated her bone marrow to her sister to replace hers after it was > deliberately destroyed by chemo/rad to stop *her* cancer. > > This was against Islamic law but she and her family felt like they had still > done the right thing. She is now hyper aware that her sister is a > Chimera, though she didn't have the term for it. She believes that her > sister underwent a radical personality change after the > transplant/recovery and wants to attribute it to the "transplant". At > first I wanted to dismiss this but on a little reflection and study, I am > more sympathetic to her position. > > The more I read about hematopoietic cell transplant and lateral genetic > transference, the curiouser it all gets! I feel like we need the molecular > biology equivalent of Oliver Sacks (RIP) in the house to bring a more popular > understanding to the table of this fascinating field! > > I was fascinated as a child to learn about tree grafting in nut and citrus > orchards, and later organ transplants in humans, but this goes a > step further since it is roughly "systemic". This also lead me to > reflect on birth-chimeras where multiple zygotes fuse early on to yield a > single fetus and ultimately full human organism but with a mixture of cells > with filial genomics. > > I have friends who are "mirror" twins who each have a third nipple on > opposite sides of their body (slightly lower than the conventional location). > They believed this to suggest that they had
Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)
"Ray Kurzweil will be rolling over in his memory bank one day when we talk like this!" Don't confuse your memmove(3) and memcpy(3).Big trouble! Marcus FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)
On 9/24/15 9:44 AM, Marcus Daniels wrote: Right! http://alcor.org/AtWork/index.html -Original Message- From: Friam [mailto:friam-boun...@redfish.com] On Behalf Of Parks, Raymond Sent: Thursday, September 24, 2015 9:39 AM To: 'friam@redfish.com' Subject: Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics) It would be much more convenient to store your head in a jar, a la Futurama. And more comedic. Ray Parks Doesn't the Alcor Splash Page just *beg* for some photo-shop action? clip off all the heads, put them in jars on a shelf? Or just settle Jars down over them en-vivo like the way pear brandy bottlers sometimes let a pear grow (into!) the bottle they are going to distribute the brandy in?Sortof a space-suit theme? Ray Kurzweil will be rolling over in his memory bank one day when we talk like this! - Steve FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)
Right! http://alcor.org/AtWork/index.html -Original Message- From: Friam [mailto:friam-boun...@redfish.com] On Behalf Of Parks, Raymond Sent: Thursday, September 24, 2015 9:39 AM To: 'friam@redfish.com' Subject: Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics) It would be much more convenient to store your head in a jar, a la Futurama. And more comedic. Ray Parks - Original Message - From: Marcus Daniels [mailto:mar...@snoutfarm.com] Sent: Thursday, September 24, 2015 09:33 AM To: The Friday Morning Applied Complexity Coffee Group Subject: [EXTERNAL] Re: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics) Well, I assume that if my connectome could be scanned with sufficient fidelity, and stored in a computer, that it would be possible, someday, to both query my memories, but also to measure emotional responses, in silico. Probably even start and stop consciousness.The trick would be figuring out the interfaces, but obvious places to start would be the visual cortex, auditory centers, and various incoming nerves.It could sort of be approaches as a machine learning problem, like is beginning to be done with replacement limbs. Sure there are aspects of my physical self that are slightly unique to me, but I would expect they are modularized. The experience of running, typing, and so on. But those things aren't me. If anything, it would seem to be thrilling to experience other real or simulated nervous systems. Yes, I know, what huge waste of disk space! Btw, what rights do the dead have to their own memories? A whole new field of IP law! -Original Message- From: Friam [mailto:friam-boun...@redfish.com] On Behalf Of Steve Smith Sent: Thursday, September 24, 2015 9:22 AM To: The Friday Morning Applied Complexity Coffee Group Subject: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics) Glen/Nick - >> Having said that, am I allowed to say, "Crap! I wish you didn't have >> cancer!' > Of course. Thanks. But just to be argumentative, ... > I am cancer. It's probably not true of all cancers, though. I recently had a long conversation with a Muslim friend from Australia who donated her bone marrow to her sister to replace hers after it was deliberately destroyed by chemo/rad to stop *her* cancer. This was against Islamic law but she and her family felt like they had still done the right thing. She is now hyper aware that her sister is a Chimera, though she didn't have the term for it. She believes that her sister underwent a radical personality change after the transplant/recovery and wants to attribute it to the "transplant". At first I wanted to dismiss this but on a little reflection and study, I am more sympathetic to her position. The more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets! I feel like we need the molecular biology equivalent of Oliver Sacks (RIP) in the house to bring a more popular understanding to the table of this fascinating field! I was fascinated as a child to learn about tree grafting in nut and citrus orchards, and later organ transplants in humans, but this goes a step further since it is roughly "systemic". This also lead me to reflect on birth-chimeras where multiple zygotes fuse early on to yield a single fetus and ultimately full human organism but with a mixture of cells with filial genomics. I have friends who are "mirror" twins who each have a third nipple on opposite sides of their body (slightly lower than the conventional location). They believed this to suggest that they had begun as triplets and that there was such a fusion during the early embryological process. I didn't recognize any other chimeric properties (sometimes evidenced by piebald skin or hair markings). This is NOT your father's Genetics! My father studied biology in the late 1940s, my own molecular biology experience is roughly circa 1984, and my daughter's PhD in molecular biology is only about 7 years old now, yet *even her* "book larnin' " in the general field, and in particular epigenetics is getting stale fast! - Steve FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com FRIAM Applied Complexity Group lis
Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)
It would be much more convenient to store your head in a jar, a la Futurama. And more comedic. Ray Parks - Original Message - From: Marcus Daniels [mailto:mar...@snoutfarm.com] Sent: Thursday, September 24, 2015 09:33 AM To: The Friday Morning Applied Complexity Coffee Group Subject: [EXTERNAL] Re: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics) Well, I assume that if my connectome could be scanned with sufficient fidelity, and stored in a computer, that it would be possible, someday, to both query my memories, but also to measure emotional responses, in silico. Probably even start and stop consciousness.The trick would be figuring out the interfaces, but obvious places to start would be the visual cortex, auditory centers, and various incoming nerves.It could sort of be approaches as a machine learning problem, like is beginning to be done with replacement limbs. Sure there are aspects of my physical self that are slightly unique to me, but I would expect they are modularized. The experience of running, typing, and so on. But those things aren't me. If anything, it would seem to be thrilling to experience other real or simulated nervous systems. Yes, I know, what huge waste of disk space! Btw, what rights do the dead have to their own memories? A whole new field of IP law! -Original Message- From: Friam [mailto:friam-boun...@redfish.com] On Behalf Of Steve Smith Sent: Thursday, September 24, 2015 9:22 AM To: The Friday Morning Applied Complexity Coffee Group Subject: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics) Glen/Nick - >> Having said that, am I allowed to say, "Crap! I wish you didn't have >> cancer!' > Of course. Thanks. But just to be argumentative, ... > I am cancer. It's probably not true of all cancers, though. I recently had a long conversation with a Muslim friend from Australia who donated her bone marrow to her sister to replace hers after it was deliberately destroyed by chemo/rad to stop *her* cancer. This was against Islamic law but she and her family felt like they had still done the right thing. She is now hyper aware that her sister is a Chimera, though she didn't have the term for it. She believes that her sister underwent a radical personality change after the transplant/recovery and wants to attribute it to the "transplant". At first I wanted to dismiss this but on a little reflection and study, I am more sympathetic to her position. The more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets! I feel like we need the molecular biology equivalent of Oliver Sacks (RIP) in the house to bring a more popular understanding to the table of this fascinating field! I was fascinated as a child to learn about tree grafting in nut and citrus orchards, and later organ transplants in humans, but this goes a step further since it is roughly "systemic". This also lead me to reflect on birth-chimeras where multiple zygotes fuse early on to yield a single fetus and ultimately full human organism but with a mixture of cells with filial genomics. I have friends who are "mirror" twins who each have a third nipple on opposite sides of their body (slightly lower than the conventional location). They believed this to suggest that they had begun as triplets and that there was such a fusion during the early embryological process. I didn't recognize any other chimeric properties (sometimes evidenced by piebald skin or hair markings). This is NOT your father's Genetics! My father studied biology in the late 1940s, my own molecular biology experience is roughly circa 1984, and my daughter's PhD in molecular biology is only about 7 years old now, yet *even her* "book larnin' " in the general field, and in particular epigenetics is getting stale fast! - Steve FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com