RE: [Histonet] RE: New Cap Guidelines for Her2 and ER/PR

2010-10-12 Thread Teri . Hallada
Sorry Jan,
 
ASCO/CAP Guideline Recommendations for HER2 in Breast Cancer Article
Table 6. Sample Exclusion Criteria to Perform or Interpret a HER2 FISH Assay
Item #3 Tissue fixed for prolonged intervals in formalin (greater than 48 hours)
 
Teresa Hallada MTCT (ASCP)
MidMichigan Health Gratiot



From: histonet-boun...@lists.utsouthwestern.edu on behalf of Mahoney,Janice A
Sent: Tue 10/12/2010 12:05 PM
To: 'Mike Pence'; Joyce Cline; histonet@lists.utsouthwestern.edu
Subject: RE: [Histonet] RE: New Cap Guidelines for Her2 and ER/PR



Formalin fixation time does not impact the results of FISH as it does IHC.
Jan M
Omaha

-Original Message-
From: Mike Pence [mailto:mpe...@grhs.net]
Sent: Tuesday, October 12, 2010 11:00 AM
To: Mahoney,Janice A; Joyce Cline; histonet@lists.utsouthwestern.edu
Subject: RE: [Histonet] RE: New Cap Guidelines for Her2 and ER/PR

I don't think it matters if you do Her2 by FISH or IHC the time is still
48hr. I hope I am wrong, but I don't think I am.

Mike

-Original Message-
From: histonet-boun...@lists.utsouthwestern.edu
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of
Mahoney,Janice A
Sent: Tuesday, October 12, 2010 10:25 AM
To: 'Joyce Cline'; histonet@lists.utsouthwestern.edu
Subject: [Histonet] RE: New Cap Guidelines for Her2 and ER/PR


We have decided to reflex to FISH those breasts that do not fall within
the recommended formalin fixation time.  We do work on Saturdays so it
is only the rare 3 day weekends that this comes into play. Jan M Omaha

-Original Message-
From: histonet-boun...@lists.utsouthwestern.edu
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of Joyce
Cline
Sent: Tuesday, October 12, 2010 10:10 AM
To: histonet@lists.utsouthwestern.edu
Subject: [Histonet] New Cap Guidelines for Her2 and ER/PR

Does anyone have any experience with storing formalin fixed breast
tissue in 70% before processing?  I am trying to comply with the new
guidelines set forth by CAP and ASCO with regard to Her2 and ER/PR and
since my lab does not operate on the weekend we have been well above the
48 hour recommended formalin fixation time.  Does 70% affect
antigenicity for either Her2 or ER/PR?  Any information or suggestions
will be greatly appreciated.  Thanks :)


Ronda Souders
Hagerstown Medical Laboratory
301-665-4980
fax 301-665-4941
ronda.soud...@wchsys.orgmailto:ronda.soud...@wchsys.org


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RE: [Histonet] new er pr cap guidelines

2010-04-20 Thread Teri . Hallada
Under the frequently asked questions on the CAP web site is the answer
to Her2.  It is still at 48 hours.

Teresa Hallada BS, MT/CT (ASCP)
Pathology Lead
MidMichigan Health - Gratiot
teri.hall...@midmichigan.org
989.463.1101 ext 3423
 

-Original Message-
From: histonet-boun...@lists.utsouthwestern.edu
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of Mike
Pence
Sent: Tuesday, April 20, 2010 11:14 AM
To: Richard Cartun; anita dudley; histonet@lists.utsouthwestern.edu
Subject: RE: [Histonet] new er pr cap guidelines

Yes, the paper is there, however, I see they addressed the fixation time
in NBF for er/pr but I do not see where they talk about the time
changing for her2. So does this mean that I have to fix some of the
tumor for her2 for only 48 hours, while the er/pr can be fixed 72 hours?

-Original Message-
From: histonet-boun...@lists.utsouthwestern.edu
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of Richard
Cartun
Sent: Tuesday, April 20, 2010 10:07 AM
To: anita dudley; histonet@lists.utsouthwestern.edu
Subject: Re: [Histonet] new er pr cap guidelines


I believe they are posted on the CAP website.

Richard

Richard W. Cartun, Ph.D.
Director, Histology  Immunopathology
Director, Biospecimen Collection Programs Assistant Director, Anatomic
Pathology Hartford Hospital 80 Seymour Street Hartford, CT  06102
(860) 545-1596 Office
(860) 545-2204 Fax


 anita dudley azdud...@hotmail.com 4/20/2010 10:46 AM 

has anyone seen the new er pr guidelines for er and pr?  my pathologist
just came through all in a tizzy about it.  just wondering if anyone
else has seen it.  the fixation times were also suppose to change,  to
72 hrs fixation for breast.

 

thanks for anybodies input,  anita, providence hosp. mobile alabama
  
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[Histonet] Temperature and Humidity Monitoring System

2010-02-05 Thread Teri . Hallada
Anyone recently price one of these for a small to medium lab? 

Teresa Hallada BS, MT/CT (ASCP)
Pathology Lead
MidMichigan Health - Gratiot
teri.hall...@midmichigan.org
989.463.1101 ext 3423

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[Histonet] Core Biopsy Her2

2009-02-16 Thread Teri . Hallada
I'm interested in how many institutions are performing Her2 on core
needle biopsies. What protocols are you following as far as formalin
fixation? The published protocol gives a minimum, but not a maximum.

Teresa Hallada BS, MT/CT (ASCP)
Lead Cytotechnologist
MidMichigan Health - Gratiot
teri.hall...@midmichigan.org
989.463.1101 ext 3423

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[Histonet] Floaters

2008-11-21 Thread Teri . Hallada
Would anyone care to share their policy on floaters? Also, does anyone
know if there is a CAP policy in floaters?

Teresa Hallada BS, MT/CT (ASCP)
Lead Cytotechnologist
MidMichigan Health - Gratiot
[EMAIL PROTECTED]
989.463.1101 ext 3423

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