[R] lme help

2006-02-08 Thread Mahdi Osman
Hi list,


I am fitting microarray data (intensity) model using the lme package in R
environment. I have 5 fixed variables in the model. One of the fixed
variables is genes. I am trying to get p-values for  different genes. But I
am getting only one p-value for all genes together. I can get a list of
p-value when I run lm. Why can't this work in lme?

My aim is to do multiple comaprison of all the genes that I have and I can
only do this if I have a list of their p-vales


I was wondering if you can help me solve this problem. That is getting
a list of p-value for each gene in the model using the lme.


Thanks in advance for your help


Regards



Mahdi 

-- 
---
Mahdi Osman (PhD)
E-mail: [EMAIL PROTECTED]

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Re: [R] lme help

2006-02-08 Thread Adaikalavan Ramasamy
Please read the posting 
1) I think BioConductor mailing list might be better as some of these
could be implemented via LIMMA (I believe)
2) Provide sufficient information and perhaps a simple example.

Regards, Adai



On Wed, 2006-02-08 at 10:42 +0100, Mahdi Osman wrote:
 Hi list,
 
 
 I am fitting microarray data (intensity) model using the lme package in R
 environment. I have 5 fixed variables in the model. One of the fixed
 variables is genes. I am trying to get p-values for  different genes. But I
 am getting only one p-value for all genes together. I can get a list of
 p-value when I run lm. Why can't this work in lme?
 
 My aim is to do multiple comaprison of all the genes that I have and I can
 only do this if I have a list of their p-vales
 
 
 I was wondering if you can help me solve this problem. That is getting
 a list of p-value for each gene in the model using the lme.
 
 
 Thanks in advance for your help
 
 
 Regards
 
 
 
 Mahdi 


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[R] lme help

2004-01-31 Thread cbotts1
Does anyone know how to fit a linear mixed effects model when the within-group 
covariance is known!I know how to fit an lme model when the within-group 
covariance STRUCTURE is known, but that doesn't help.

Any help would be greatly appreciated!

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