CSCataract Research: Comment

[Brooks Bradley]

I noticed, a comment among the recent commentary on my earlier post on some of
our cataract research mentioned the application of 100%, undiluted DMSO.  While we have never encountered any case where the externalor internaluse of undiluted DMSO has resulted in ANY measurable degree of tissue compromisethere ARE circumstances where the result of such application has a PRONOUNCED rush of marked discomfort.  The burning sensation resulting from such protocols is, sometimes, called "false blister", as it feels almost identical to a pronounced sunburn. A majority of all such incidents (among those we have encountered) result from a single cause.which is the immediate rush of DMSO responding to its powerful hygroscopic character.  The actual effect of introducing pure/undiluted DMSO will vary---sometimes, remarkably so
based upon the fact that the actual volume/availability of moisture existing in the eye socket at the time of application varies widely among persons.many times as much as 50%.  Such conditions set the stage for a most uncomfortable reaction.at the precise moment of introducing the DMSO to the eye surface/socket environment.  The less the volume of existing moisture/tears present at this moment.the more pronounced the potential discomfort to the recipient.  I repeat myself from earlier cautions:  DMSO is EXTREMELY hygroscopic, to the extent that in some cases, if inadvertently having water poured into the vessel containing the parent, undiluted, DMSOThe reaction is so violent that liquid material will be ejected in the form of large bubbles/misttogether with the generation of pronounced heat. Even when mixed properly with other liquids containing water fractionsDMSO ALWAYS causes a reaction which liberates heat.
 We have failed to encounter many circumstance where solutions containing DMSO, require strengths beyond 20%and in most cases, not beyond 10%.  Exceptions include normal, external, non-abraded, skin tissues.
 I do not mean to "gild-the-lily"  with these comments, but do feel they are worth ones consideration.  Especially in view of the fact we have such a wide disparity in technical/biological and chemical knowledge among the list membership.
 I consider ALL members to be intelligent.but not equally informed.
Sincerely,   Brooks Bradley.



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Re: CSCataract Research: Comment

[Annie B Smythe]

Do you have a website? I am interested in reading everything you've got 
available on the subject...


Annie

Brooks Bradley wrote:
I noticed, a comment among the recent commentary on my earlier post on 
some of
our cataract research mentioned the application of 100%, undiluted 
DMSO. While we have never encountered any case where the 
externalor internaluse of undiluted DMSO has resulted in ANY 
measurable degree of tissue compromisethere ARE circumstances 
where the result of such application has a PRONOUNCED rush of marked 
discomfort. The burning sensation resulting from such protocols is, 
sometimes, called false blister, as it feels almost identical to a 
pronounced sunburn. A majority of all such incidents (among those we 
have encountered) result from a single cause.which is the 
immediate rush of DMSO responding to its powerful hygroscopic 
character. The actual effect of introducing pure/undiluted DMSO will 
vary---sometimes, remarkably so
based upon the fact that the actual volume/availability of moisture 
existing in the eye socket at the time of application varies widely 
among persons.many times as much as 50%. Such conditions set the 
stage for a most uncomfortable reaction.at the precise moment of 
introducing the DMSO to the eye surface/socket environment. The less 
the volume of existing moisture/tears present at this moment.the 
more pronounced the potential discomfort to the recipient. I repeat 
myself from earlier cautions: DMSO is EXTREMELY hygroscopic, to the 
extent that in some cases, if inadvertently having water poured into 
the vessel containing the parent, undiluted, DMSOThe reaction is 
so violent that liquid material will be ejected in the form of large 
bubbles/misttogether with the generation of pronounced heat. Even 
when mixed properly with other liquids containing water 
fractionsDMSO ALWAYS causes a reaction which liberates heat.
We have failed to encounter many circumstance where solutions 
containing DMSO, require strengths beyond 20%and in most cases, 
not beyond 10%. Exceptions include normal, external, non-abraded, skin 
tissues.
I do not mean to gild-the-lily with these comments, but do feel they 
are worth ones consideration. Especially in view of the fact we have 
such a wide disparity in technical/biological and chemical knowledge 
among the list membership.

I consider ALL members to be intelligent.but not equally informed.
Sincerely, Brooks Bradley.
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Silver. Instructions for unsubscribing are posted at: 
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silver-off-topic-l...@eskimo.com The Silver List and Off Topic List 
archives are currently down... List maintainer: Mike Devour