Re: CSResearch Site - Cell-Penetrating Peptides

2009-03-10 Thread craehow...@juno.com
thanks marshall...
You make it much easier to understand.
connie
 

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Re: CSResearch Site - Cell-Penetrating Peptides

2009-03-09 Thread Marshall Dudley

craehow...@juno.com wrote:


http://www.springerlink.com/content/q102950x6u710304/

I accidently ran into this site and what I could understand sound 
similiar to DMSO


they are doing research... anyone out there out there with this type 
background care to take a peak and tell us in lay persons terms.


thanks

connie




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They are using other substances for transport, like DMSO, but the 
similarity ends there.  DMSO transports by dissolving the substance, 
then diffusing as a solution though the skin or other substance.  They 
are talking about binding substances to peptides and using that to allow 
transport through biological barriers.   This is closer to chelation, 
than DMSO.  The substance to be transported through the barrier is 
hidden by or inside the peptide, so that the barrier does not see it, 
and givea the ok for the peptide to cross the barrier. That is why they 
are referring to it as a Trojan horse.  The comparison is like if you 
want to get a drug to go through some filter paper, you would dissolve 
it into some water, or DMSO, and it would then have the mobility to flow 
through the paper. But if you want to get it into a police station with 
monitors at the door, you put it inside a candy bar or something.


Marshall


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CSResearch Site - Cell-Penetrating Peptides

2009-03-07 Thread craehow...@juno.com
http://www.springerlink.com/content/q102950x6u710304/
I accidently ran into this site and what I could understand sound similiar to 
DMSO
they are doing research... anyone out there out there with this type background 
care to take a peak and tell us in lay persons terms.
thanks
connie

Click to get free auto insurance quotes from top companies.
http://thirdpartyoffers.juno.com/TGL2131/fc/BLSrjnsHEaB8IrhNw1a2PShnAsKDr6k3tVoniyoLwmpT7I9WxR6A2SsCm3m/