There are 8 chapters altogether, plus a  section on Acknowledgments and 
another on Comments by Scientists and Others. On  the left hand side of the 
webpages are links to all the chapters/sections. There  are aslo several links 
in each chapter - I have not put in the urls so please go  to the websites. 
 
I have wondered for years what happened  to L-tryptophan. It seems it would 
be very helpful to many of those with pain,  sleep difficulties, 
Fibromyalgia, and many other conditions. Well, I guess now I  
know.........except why 
is it still not available? or was this just an excuse  for the FDA and 
Health Canada as they collaborate with Codex.......is this what  the future 
holds 
for Canada and the USA?  best wishes,  Shan
 (http://www.papercut.biz/emailStripper.htm)  

Toxic L-tryptophan:  Shedding Light on a Mysterious Epidemic 
_http://www.seedsofdeception.com/Public/L-tryptophan/index.cfm_ 
(http://www.seedsofdeception.com/Public/L-tryptophan/index.cfm)   
by William E.Crist  

Preface by Jeffrey  Smith                                                   
                                             
_http://www.seedsofdeception.com/Public/L-tryptophan/PrefacebyJeffreySmith/index.cfm_
 
(http://www.seedsofdeception.com/Public/L-tryptophan/PrefacebyJeffreySmith/index.cfm)
      In 
chapter 4 of my book Seeds of Deception, I  present the story of a deadly 
epidemic in 1989 that was linked to an  L-tryptophan food supplement produced 
by 
genetically engineered bacterium. Much  of the material was based on the 
research of William Crist, whose work is  reproduced here.  

Introduction: Was  Genetic Engineering the Cause of Contaminated 
L-tryptophan and the EMS  Epidemic?                                             
       
            
_http://www.seedsofdeception.com/Public/L-tryptophan/1Introduction/index.cfm_ 
(http://www.seedsofdeception.com/Public/L-tryptophan/1Introduction/index.cfm)   
           Knowing my long-standing interest in food 
purity issues, a friend in California  suggested in 1996 that I look into the 
cause of the tragic eosinophilia-myalgia  syndrome (EMS) epidemic that had 
struck seven years earlier. The outbreak was  traced to consumption of 
L-tryptophan food supplements produced by a Japanese  company using genetically 
engineered (GE) bacteria. Exactly what role  biotechnology played in the 
contamination of the supplement was hotly debated.  After thousands of hours of 
self-sponsored research, I believe I can shed some  light on that issue.  

Background Information:  The EMS Epidemic, Initial Research Studies and 
News of Biotech  Link                                                           
                                   
_http://www.seedsofdeception.com/Public/L-tryptophan/2BackgroundInformation/index.cfm_
 
(http://www.seedsofdeception.com/Public/L-tryptophan/2BackgroundInformation/index.cfm)
                    
                                                         During the summer 
and autumn of 1989, an outbreak of a tragic and mysterious  disease swept 
across the U.S. First scores, then hundreds of people fell  seriously ill with 
a rare blood and muscle disorder. Doctors and hospital staffs  were baffled 
by the unusual cluster of symptoms and were largely ineffective in  
treating the victims.  

The Pre-epidemic Cases:  A Key to the EMS Puzzle? 
_http://www.seedsofdeception.com/Public/L-tryptophan/3Pre-epidemicCases-KeytoEMSPuzzle/index.cfm_
 
(http://www.seedsofdeception.com/Public/L-tryptophan/3Pre-epidemicCases-KeytoEMS
Puzzle/index.cfm)                                                           
                                               **The existence of cases 
prior to those that constituted the great bulk of the  epidemic is one of the 
most peculiar and interesting aspects of the EMS  outbreak.**                 
                  — Edwin M. Kilbourne,1 epidemiologist, Center for Disease 
Control  
For more than a decade now,  researchers have been puzzled by cases of EMS 
that occurred for several years  prior to the epidemic.  

Where Did the  Contaminants Come From?    
_http://www.seedsofdeception.com/Public/L-tryptophan/4WhereDidtheContaminant
sComeFrom/index.cfm_ 
(http://www.seedsofdeception.com/Public/L-tryptophan/4WhereDidtheContaminantsComeFrom/index.cfm)
 
**Although the [20kg/batch] powdered carbon may have contributed to the  
removal of the etiological [causal] agent, it does not explain how the agent 
was  introduced into the  product.**
—Edward Belongia,  M.D., et al., The New England Journal of Medicine 1 
It*s been more than a decade since  Belongia and his colleagues raised this 
salient point about what created the  contaminants that caused EMS. 
Surprisingly, few researchers have addressed  it. 

Problems with Identifying  and Testing for Trace Contaminants 
_http://www.seedsofdeception.com/Public/L-tryptophan/5ProblemswithIdentificationTesting/in
dex.cfm_ 
(http://www.seedsofdeception.com/Public/L-tryptophan/5ProblemswithIdentificationTesting/index.cfm)
                                             
                 **I must emphasize that the presence of the contaminants 
in the [Showa Denko]  L-tryptophan is astonishingly small and so you require 
very sophisticated  instrumentation and a lot of hard work to even come 
close to determining the  structures.**                                    —
Stephen Naylor, Mayo Clinic1  

Government Agencies  Disagree on Cause of EMS 
_http://www.seedsofdeception.com/Public/L-tryptophan/6GovtAgenciesDisagreeonEMSCause/index.cfm_
 
(http://www.seedsofdeception.com/Public/L-tryptophan/6GovtAgenciesDisagreeonEMSCause/i
ndex.cfm)                                                  The FDA*s 
finding that control L-tryptophan itself was a contributing factor to  the 
syndrome is surprising, because it is inconsistent with the epidemiological  
evidence linking production lots of implicated L-TRP to cases of EMS. Earlier  
studies by leading researchers, including those at the Center for Disease  
Control (CDC), clearly suggested that L-tryptophan itself was not responsible  
for EMS and that the disease was caused by contaminant(s) in a single  
manufacturer’s L-TRP.1-3  

Unanswered Letters to  Government  Officials                             
_http://www.seedsofdeception.com/Public/L-tryptophan/7UnansweredLetterstoGovtOf
ficials/index.cfm_ 
(http://www.seedsofdeception.com/Public/L-tryptophan/7UnansweredLetterstoGovtOfficials/index.cfm)
                                    
                               This section includes three letters sent to 
government regulatory authorities  and researchers concerning: 
(1) key information and/or data that appears to  have been concealed from 
the public regarding L-tryptophan and the EMS epidemic,  and 
(2) discrepancies in the interpretation of research data and in the  
procurement of samples of Showa Denko's (SDK) genetically engineered strains of 
 
bacteria. After several months, and now years, no one from either the 
National  Centers for Disease Control or the Food and Drug Administration has 
answered  several key, material questions.  

Conclusion: Who’s  Responsible?                                            
_http://www.seedsofdeception.com/Public/L-tryptophan/8ConclusionWhosResponsib
le/index.cfm_ 
(http://www.seedsofdeception.com/Public/L-tryptophan/8ConclusionWhosResponsible/index.cfm)
                                                
                      What created the biologically potent trace 
contaminants in Showa Denko  L-tryptophan that inflicted a seriously 
debilitating 
disease at such low dosages  of a food supplement?  
Researchers still do not know.  Some, like Gleich and Maryanski, have 
stated that genetic engineering can’t be  ruled out as a causal factor, though 
they favor other scenarios, usually the  manufacturer’s inadequate 
purification system.  

Acknowledgments                                                             
                     
_http://www.seedsofdeception.com/Public/L-tryptophan/Acknowledgments/index.cfm_ 
(http://www.seedsofdeception.com/Public/L-tryptophan/Acknowledgments/index.cfm) 
  
Addendum: Comments by  Scientists and Other  Professionals                  
        
_http://www.seedsofdeception.com/Public/L-tryptophan/CommentsbyScientistsandOthers/index.cfm_
 
(http://www.seedsofdeception.com/Public/L-tryptophan/CommentsbyScientistsandOthers/index.cfm)
  
 (http://www.papercut.biz/emailStripper.htm) 





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