[Reposting from an approved email address]
Hi Benilton,
The locus level (total) CN ratios passed to CBS is simply the
log2(T/R), where 'T' is the total CN signal (no ratio) for sample T
("tumor" say) and 'R' is ditto for the reference used to standardize
(aka "normalize" by some books). Typical
Hi everyone,
if you check the image at:
https://dl.dropboxusercontent.com/u/83643/Screen%20Shot%202015-05-20%20at%201.50.50%20AM.png
you'll see segmentation results for a few human samples across multiple
chromosomes. This was achieved via CBS (under the aroma framework,
therefore CbsModel).
