In the PSCBS package, we provide the `estimateKappa()` function for
estimating kappa, which we refer to as "background signal", cf.
https://cran.r-project.org/web/packages/PSCBS/vignettes/PairedPSCBS.pdf.
The kappa parameter is strongly correlated with the amount of normal
contamination. We're ver
Is there a way to incorporate tumor purity estimates (e.g. from ASCAT) into
the Aroma pipeline for segmenting copy number changes between parent and
tumor? We are looking at cell lines derived from tumors to compare
consistency between copy number variations. The tumor purity in the
parental
