Hi,

I'm pleased to announce that the CRMA v2 vignette is now available online:

  Vignette 'Estimation of total copy numbers using the CRMA v2 method (10K-6.0)'
  
http://groups.google.com/group/aroma-affymetrix/web/estimation-of-total-copy-numbers-using-the-crma-v2-method

The CRMA v2 method is a single-array method for estimating
full-resolution raw CNs by correcting for allelic crosstalk,
nucleotide-probe position effects, and PCR fragment-length effects.
The paper describing all details has been submitted early November and
if everything goes well it will hopefully be available soonish.  In
that manuscript we also show that the estimates are equally good or
better than estimates produces by Affymetrix GTC v3.0 and dChip.  This
is inline with our collaborators reporting that CRMAv2 estimates seem
to have better signal-to-noise ratios.

Please report any hickups, errors in the script or language problems
in the vignette.  As with everything else in aroma.affymetrix, any
kind of contributions to the documentation or the source are useful.

Cheers

Henrik

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