unsubsribe please

> ----------
> From:         Rien[SMTP:[EMAIL PROTECTED]]
> Reply To:     [EMAIL PROTECTED]
> Sent:         09 Juni 2000 9:04
> To:   [EMAIL PROTECTED]
> Subject:      [balita-anda] Imunisasi saat hamil - artikel panjang (was :
> suntik tetanus ??
> 
> Rekan2,
> menyambung diskusi soal imunisasi Tetanus saat hamil, ini ada artikel
> dari www.cdc.gov (wah, bukan 'mania' CDC nih, tapi karena belakangan
> surfing ke sana dan ketemu yg. menarik2...).
> Pengalaman pribadi sih, dulu waktu hamil tidak diberi suntikan TT, tapi
> sepulang dari RS sesudah kena campak dulu itu, DSOG saya menyarankan
> untuk vaksin Rubella, karena dari cek darah, belum ada antibodi tsb.
> Cuma saya harus tidak boleh hamil sampai 3 bulan sesudahnya. Jadi beliau
> menyarankan divaksin saat menstruasi, supaya bener2 yakin sedang tidak
> hamil.
> Semoga artikel ini berguna.
> Semoga juga belum 40 KB...:-)
> --
>     \\\
>     ( o>    Salam,
>     /U )    Rien.
>  ----oo---
> 
> 
> Vaccination of Pregnant Women
> 
>     "Risk from vaccination during pregnancy is largely theoretical. The
>     benefit of vaccination among pregnant women usually outweighs the
>     potential risk when a) the risk for disease exposure is high, b)
>     infection would pose a special risk to the mother or fetus, and c)
>     the vaccine is unlikely to cause harm." ACIP General
>     Recommendations on Immunization, p. 20
> 
>     Generally, live-virus vaccines are contraindicated for pregnant
>     women because of the theoretical risk of transmission of the
>     vaccine virus to the fetus. If a live-virus vaccine is
>     inadvertently given to a pregnant woman, or if a woman becomes
>     pregnant within 3 months after vaccination, she should be counseled
>     about the potential effects on the fetus. But it is not ordinarily
>     an indication to terminate the pregnancy.
> 
>     Whether live or inactivated vaccines are used, vaccination of
>     pregnant women should be considered on the basis of risks vs.
>     benefits - i.e., the risk of the vaccination vs. the benefits of
>     protection in a particular circumstance. The following table may be
>     used as a general guide.
> 
> -------------------------------------
>     Passive Immunization during Pregnancy
> 
>     "There is no known risk to the fetus from passive immunization of
>     pregnant women with immune globulin preparations." ACIP General
>     Recommendations on Immunization, p. 21
> 
>            In the following table, relevant passages from ACIP
>            recommendations are reprinted for each vaccine.
>            Material in quotation marks is taken verbatim from
>            ACIP (emphasis in bold type added); material not in
>            quotation marks is paraphrased.
> 
> ----------------------------------------------------
> 
>                  Guidelines for Vaccinating Pregnant Women
>                    Abstracted from recommendations of the
>             Advisory Committee on Immunization Practices (ACIP)
> 
> 
>      HEPATITIS A          * "The safety of hepatitis A vaccination
>                           during pregnancy has not been determined;
>                           however, because hepatitis A vaccine is
>                           produced from inactivated [hepatitis A
>                           virus], the theoretical risk to the
>                           developing fetus is expected to be low. The
>                           risk associated with vaccination should be
>                           weighed against the risk for hepatitis A in
>                           women who may be at high risk for exposure
>                           to [hepatitis A virus]." (1)
> 
>      HEPATITIS B          * "On the basis of limited experience, there
>                           is no apparent risk of adverse effects to
>                           developing fetuses when hepatitis B vaccine
>                           is administered to pregnant women (CDC,
>                           unpublished data). The vaccine contains
>                           noninfectious HBsAg particles and should
>                           cause no risk to the fetus. [Hepatitis B
>                           virus] infection affecting a pregnant woman
>                           may result in severe disease for the mother
>                           and chronic infection for the newborn.
>                           Therefore, neither pregnancy nor lactation
>                           should be considered a contraindication to
>                           vaccination of women."(2)
> 
>                           * "Hepatitis B vaccine is recommended for
>                           women at risk for hepatitis B infection . .
>                           ." (3)
> 
>      INFLUENZA            * "On the basis of . . . data that suggest
>                           that influenza infection may cause increased
>                           morbidity in women during the second and
>                           third trimesters of pregnancy, the [ACIP]
>                           recommends that women who will be beyond the
>                           first trimester of pregnancy (>14 weeks'
>                           gestation) during the influenza season be
>                           vaccinated." (4)
> 
>                           * "Pregnant women who have medical
>                           conditions that increase their risk for
>                           complications from influenza should be
>                           vaccinated before the influenza
>                           season--regardless of the state of
>                           pregnancy." (4)
> 
>                           * "Studies of influenza immunization of more
>                           than 2,000 pregnant women have demonstrated
>                           no adverse fetal effects associated with
>                           influenza vaccine; however, more data are
>                           needed." (4)
> 
>      MEASLES              * "MMR and its component vaccines should not
>                           be administered to women known to be
>                           pregnant. Because a risk to the fetus from
>                           administration of these live virus vaccines
>                           cannot be excluded for theoretical reasons,
>                           women should be counseled to avoid becoming
>                           pregnant for 30 days after vaccination with
>                           measles or mumps containing vaccines and for
>                           3 months after administration of MMR or
>                           other rubella-containing vaccines." (5)
> 
>                           * "If a pregnant woman is vaccinated or if
>                           she becomes pregnant within 3 months after
>                           vaccination, she should be counseled about
>                           the theoretical basis of concern for the
>                           fetus, but MMR vaccination during pregnancy
>                           should not ordinarily be a reason to
>                           consider termination of pregnancy." (5)
> 
>      MUMPS                * "MMR and its component vaccines should not
>                           be administered to women known to be
>                           pregnant. Because a risk to the fetus from
>                           administration of these live virus vaccines
>                           cannot be excluded for theoretical reasons,
>                           women should be counseled to avoid becoming
>                           pregnant for 30 days after vaccination with
>                           measles or mumps containing vaccines and for
>                           3 months after administration of MMR or
>                           other rubella-containing vaccines." (5)
> 
>                           * "If a pregnant woman is vaccinated or if
>                           she becomes pregnant within 3 months after
>                           vaccination, she should be counseled about
>                           the theoretical basis of concern for the
>                           fetus, but MMR vaccination during pregnancy
>                           should not ordinarily be a reason to
>                           consider termination of pregnancy." (5)
> 
>      PNEUMOCOCCAL         * "The safety of pneumococcal polysaccharide
>                           vaccine during the first trimester of
>                           pregnancy has not been evaluated, although
>                           no adverse consequences have been reported
>                           among newborns whose mothers were
>                           inadvertently vaccinated during pregnancy."
>                           (6)
> 
>      POLIO                * "Although no adverse effects of OPV or IPV
>                           have been documented among pregnant women or
>                           their fetuses, vaccination of pregnant women
>                           should be avoided. However, if a pregnant
>                           woman requires immediate protection against
>                           poliomyelitis, she may be administered OPV
>                           or IPV in accordance with the recommended
>                           schedules for adults." (7)
> 
>      RUBELLA              * "MMR and its component vaccines should not
>                           be administered to women known to be
>                           pregnant. Because a risk to the fetus from
>                           administration of these live virus vaccines
>                           cannot be excluded for theoretical reasons,
>                           women should be counseled to avoid becoming
>                           pregnant for 30 days after vaccination with
>                           measles or mumps containing vaccines and for
>                           3 months after administration of MMR or
>                           other rubella-containing vaccines." (5)
> 
>                           * "If a pregnant woman is vaccinated or if
>                           she becomes pregnant within 3 months after
>                           vaccination, she should be counseled about
>                           the theoretical basis of concern for the
>                           fetus, but MMR vaccination during pregnancy
>                           should not ordinarily be a reason to
>                           consider termination of pregnancy." (5)
> 
>                           * "Rubella-susceptible women who are not
>                           vaccinated because they state they are or
>                           may be pregnant should be counseled about
>                           the potential risk for CRS and the
>                           importance of being vaccinated as soon as
>                           they are no longer pregnant." (5)
> 
>                           * A registry of susceptible women vaccinated
>                           with rubella vaccine between 3 months before
>                           and 3 months after conception - the "Vaccine
>                           in Pregnancy (VIP) Registry" - was kept
>                           between 1971 and 1989. No evidence of CRS
>                           occurred in the offspring of the 226 women
>                           who received the current RA 27/3 rubella
>                           vaccine and continued their pregnancy to
>                           term. (5)
> 
>      TETANUS & DIPHTHERIA * "Combined tetanus and diphtheria toxoids
>                           are . . . routinely indicated for
>                           susceptible pregnant women. Previously
>                           vaccinated pregnant women who have not
>                           received a Td vaccination within the last 10
>                           years should receive a booster dose." (8)
> 
>                           * "Pregnant women who are unimmunized or
>                           only partially immunized against tetanus
>                           should complete the primary series." (8)
> 
>                           * "Although no evidence exists that tetanus
>                           and diphtheria toxoids are teratogenic,
>                           waiting until the second trimester of
>                           pregnancy to administer Td is a reasonable
>                           precaution for minimizing any concern about
>                           the theoretical possibility of such
>                           reactions." (9)
> 
>      VARICELLA            * "The effects of the varicella virus
>                           vaccine on the fetus are unknown; therefore,
>                           pregnant women should not be vaccinated.
>                           Nonpregnant women who are vaccinated should
>                           avoid becoming pregnant for 1 month
>                           following each injection. For susceptible
>                           persons, having a pregnant household member
>                           is not a contraindication to vaccination."
>                           (10)
> 
>                           * "If a pregnant woman is vaccinated or
>                           becomes pregnant within 1 month of
>                           vaccination, she should be counseled about
>                           potential effects on the fetus." (10)
> 
>                           * "Because the virulence of the attenuated
>                           virus used in the vaccine is less than that
>                           of the wild-type virus, the risk to the
>                           fetus, if any, should be even lower." (10)
> 
>                           * "In most circumstances, the decision to
>                           terminate a pregnancy should not be based on
>                           whether vaccine was administered during
>                           pregnancy." (10)
> 
>                           * "VZIG [Varicella Zoster Immune Globulin]
>                           should be strongly considered for
>                           susceptible, pregnant women who have been
>                           exposed." (10)
> 
>                           * The manufacturer & CDC have established a
>                           VARIVAX® Pregnancy Registry to monitor
>                           outcomes of women who got the vaccine 3
>                           months before or any time during pregnancy.
>                           Call 1-800-986-8999.
> 
>      BCG                  * "Although no harmful effects to the fetus
>                           have been associated with BCG vaccine, its
>                           use is not recommended during pregnancy."
>                           (11)
> 
>      CHOLERA              * "No specific information exists on the
>                           safety of cholera vaccine during pregnancy.
>                           Its use should be individualized to reflect
>                           actual need." (12)
> 
>      JAPANESE             * "No specific information is available on
>      ENCEPHALITIS         the safety of JE vaccine in pregnancy.
>                           Vaccination poses an unknown but theoretical
>                           risk to the developing fetus, and the
>                           vaccine should not be routinely administered
>                           during pregnancy." (13)
> 
>                           * "Pregnant women who must travel to an area
>                           where risk of JE is high should be
>                           vaccinated when the theoretical risks of
>                           immunization are outweighed by the risk of
>                           infection to the mother and developing
>                           fetus." (13)
> 
>      MENINGOCOCCAL        * Studies have shown the vaccine to be both
>                           safe and efficacious when given to pregnant
>                           women. While high antibody levels were found
>                           in umbilical cord blood following
>                           vaccination during pregnancy, antibody
>                           levels in the infants decreased during the
>                           first few months after birth. Subsequent
>                           response to meningococcal vaccination was
>                           not affected.
> 
>                           * "Based on data from studies involving use
>                           of meningococcal vaccines administered
>                           during pregnancy, altering meningococcal
>                           vaccination recommendations during pregnancy
>                           is unnecessary." (14)




> 
>      PLAGUE               * "The effects of plague vaccine on the
>                           developing fetus. . . are unknown. Pregnant
>                           women who cannot avoid high-risk situations
>                           should be advised of risk-reduction
>                           practices and should be vaccinated only if
>                           the potential benefits of vaccination
>                           outweigh potential risks to the fetus." (15)
> 
>      RABIES               * "Because of the potential consequences of
>                           inadequately treated rabies exposure, and
>                           because there is no indication that fetal
>                           abnormalities have been associated with
>                           rabies vaccination, pregnancy is not
>                           considered a contraindication to
>                           postexposure prophylaxis." (16)
> 
>                           * "If there is substantial risk of exposure
>                           to rabies, preexposure prophylaxis may also
>                           be indicated during pregnancy." (16)
> 
>      TYPHOID              * "No data have been reported on the use of
>                           any of the three typhoid vaccines among
>                           pregnant women." (17)
> 
>      VACCINIA             * "Vaccinia should not be administered to
>                           pregnant women." (18)
> 
>                           * "On rare occasions, almost always after
>                           primary vaccination, vaccinia virus has been
>                           reported to cause fetal infection. . . .
>                           Vaccinia vaccine is not known to cause
>                           congenital malformations." (18)
> 
>      YELLOW FEVER         * "Although specific information is not
>                           available concerning adverse effects of
>                           yellow fever vaccine on the developing
>                           fetus, pregnant women theoretically should
>                           not be vaccinated, and travel to areas where
>                           yellow fever is present should be postponed
>                           until after delivery." (19)
> 
>                           * "If international travel requirements
>                           constitute the only reason to vaccinate a
>                           pregnant woman, rather than an increased
>                           risk of infection, efforts should be made to
>                           obtain a waiver letter from the traveler's
>                           physician." (19)
> 
>                           * "Pregnant women who must travel to areas
>                           where the risk of yellow fever is high
>                           should be vaccinated. Under these
>                           circumstances, for both mother and fetus,
>                           the small theoretical risk from vaccination
>                           is far outweighed by the risk of yellow
>                           fever infection." (19)
> 
> --------------------------------------------------
> 
>             Prenatal Screening for Vaccine-Preventable Diseases
> 
>      The ACIP currently recommends prenatal screening for rubella and
>      hepatitis B:
> 
>      "Prenatal serologic screening . . . is indicated for all pregnant
>      women who lack acceptable evidence of rubella immunity. Upon
>      completion or termination of their pregnancies, women who do not
>      have serologic evidence of rubella immunity or documentation of
>      rubella vaccination should be vaccinated with MMR before discharge
>      from the hospital, birthing center, or abortion clinic." ACIP,
>      Measles, Mumps, and Rubella -- Vaccine Use and Strategies for
>      Elimination of Measles, Rubella, and Congenital Rubella Syndrome
>      and Control of Mumps, p. 18.
> 
>      "All pregnant women should be routinely tested for HBsAg during an
>      early prenatal visit in each pregnancy. . . . HBsAg-positive
>      mothers identified during screening may have HBV-related acute or
>      chronic liver disease and should be evaluated by their
>      physicians." ACIP, Protection Against Viral Hepatitis, p. 14.
> 
> --------------------------------------------------
> 
>                   Vaccinating Women who are Breastfeeding
> 
>      "Neither killed nor live vaccines affect the safety of
>      breast-feeding for mothers or infants. Breast-feeding does not
>      adversely affect immunization and is not a contraindication for
>      any vaccine." ACIP, General Recommendations on Immunization, p.
>      20.
> 
>      The following applies to varicella vaccine, which was licensed
>      after the ACIP General Recommendations were published: "Whether
>      attenuated vaccine VZV is excreted in human milk and, if so,
>      whether the infant could be infected are not known. Most live
>      vaccines have not been demonstrated to be secreted in breast milk.
>      Attenuated rubella vaccine virus has been detected in breast milk
>      but has produced only asymptomatic infection in the nursing
>      infant. Therefore, varicella vaccine may be considered for a
>      nursing mother." ACIP, Prevention of Varicella, pp. 19-20.
> 
> 
> 
> 
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