Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Gabe Becker
Sean and Vincent, The goal of what we are doing builds off of what Martin has in GSEABase. We were looking to see how much benefit we can get with something lighter-weight that lies between indistinguishable character vectors and the full machinery of GeneSets. Either way, it seems like formalizi

[Bioc-devel] BiocParallel-devel error

2014-09-20 Thread Thomas Girke
Hi Martin, Micheal and Vincent, If I run the following code, with the release version of BiocParallel then it works (took me some time to actually realize that), but with the development version I am getting an error shown after the test code below. If I run the same test with BatchJobs from the

Re: [Bioc-devel] coerce ExpressionSet to SummarizedExperiment

2014-09-20 Thread Hector Corrada Bravo
Would be very useful in epivizr. Right now we have a little bit of code that can be made much more general: https://github.com/epiviz/epivizr/blob/master/R/register-methods.R#L73 On Sat, Sep 20, 2014 at 5:19 PM, Michael Love wrote: > On Sep 20, 2014 2:15 PM, "Martin Morgan" wrote: > > > > On 0

Re: [Bioc-devel] coerce ExpressionSet to SummarizedExperiment

2014-09-20 Thread Michael Love
On Sep 20, 2014 2:15 PM, "Martin Morgan" wrote: > > On 09/20/2014 10:43 AM, Sean Davis wrote: >> >> Hi, Vince. >> >> Looks like a good start. I'd probably pull all the assays from >> ExpressionSet into SummarizedExperiment as the default, avoiding data >> coercion methods that are unnecessarily l

Re: [Bioc-devel] hedgehog Subversion server upgrade Tuesday 9/30

2014-09-20 Thread Dan Tenenbaum
- Original Message - > From: "Kasper Daniel Hansen" > To: "Dan Tenenbaum" > Cc: "bioc-devel" > Sent: Wednesday, September 17, 2014 5:35:50 PM > Subject: Re: [Bioc-devel] hedgehog Subversion server upgrade Tuesday 9/30 > > > The standard install of subversion on a recent Mac is 1.7.10

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Vincent Carey
On Sat, Sep 20, 2014 at 3:11 PM, Gabe Becker wrote: > Hey all, > > We are in the (very) early stages of experimenting with something that > seems relevant here: classed identifiers. We are using them for > database/mart queries, but the same concept could be useful for the cases > you're describi

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Sean Davis
On Sat, Sep 20, 2014 at 3:11 PM, Gabe Becker wrote: > Hey all, > > We are in the (very) early stages of experimenting with something that > seems relevant here: classed identifiers. We are using them for > database/mart queries, but the same concept could be useful for the cases > you're describi

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Gabe Becker
Hey all, We are in the (very) early stages of experimenting with something that seems relevant here: classed identifiers. We are using them for database/mart queries, but the same concept could be useful for the cases you're describing I think. E.g. > mysyms = GeneSymbol(c("BRAF", "BRCA1")) > my

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Vincent Carey
OK by me to leave [ alone. We could start with subsetByEntrez, subsetByKEGG, subsetBySymbol, subsetByGOTERM, subsetByGOID. Utilities to generate GRanges for queries in each of these vocabularies should, perhaps, be in the OrganismDb space? Once those are in place no additional infrastructure is

Re: [Bioc-devel] coerce ExpressionSet to SummarizedExperiment

2014-09-20 Thread Martin Morgan
On 09/20/2014 10:43 AM, Sean Davis wrote: Hi, Vince. Looks like a good start. I'd probably pull all the assays from ExpressionSet into SummarizedExperiment as the default, avoiding data coercion methods that are unnecessarily lossy. Also, as it stands, the assayname argument is not used anyway

Re: [Bioc-devel] coerce ExpressionSet to SummarizedExperiment

2014-09-20 Thread Sean Davis
Hi, Vince. Looks like a good start. I'd probably pull all the assays from ExpressionSet into SummarizedExperiment as the default, avoiding data coercion methods that are unnecessarily lossy. Also, as it stands, the assayname argument is not used anyway? Sean On Sat, Sep 20, 2014 at 10:38 AM,

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Tim Triche, Jr.
Agreed with Sean, having tried implementing to "magical" alternative --t > On Sep 20, 2014, at 9:31 AM, Sean Davis wrote: > > Hi, Vince. > > I'm coming a little late to the party, but I agree with Kasper's sentiment > that the less "magical" approach of using subsetByXXX might be the cleaner >

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Sean Davis
Hi, Vince. I'm coming a little late to the party, but I agree with Kasper's sentiment that the less "magical" approach of using subsetByXXX might be the cleaner way to go for the time being. Sean On Sat, Sep 20, 2014 at 10:42 AM, Vincent Carey wrote: > > https://github.com/vjcitn/biocMultiAss

[Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Vincent Carey
https://github.com/vjcitn/biocMultiAssay/blob/master/vignettes/SEresolver.Rnw shows some modifications to [ that allow subsetting of SE by gene or pathway name it may be premature to work at the [ level. Kasper suggested defining a suite of subsetBy operations that would accomplish this i think

[Bioc-devel] coerce ExpressionSet to SummarizedExperiment

2014-09-20 Thread Vincent Carey
do we have a facility for this? if not, we have https://github.com/vjcitn/biocMultiAssay/blob/master/R/exs2se.R https://github.com/vjcitn/biocMultiAssay/blob/master/man/coerce-methods.Rd it occurred to me that we might want something like this in GenomicRanges (that's where SummarizedExperiment