Re: [Bioc-devel] Failed to load resource from AnnotationHub

I noted the same resource causing the same error for the OSCA books in BIoC 3.20 and Lori said she'll take a look at it tomorrow (only on Slack, sorry: https://community-bioc.slack.com/archives/CM2CUGBGB/p1719265237989709) On Tue, 25 Jun 2024 at 12:21, Shian Su via Bioc-devel <

Re: [Bioc-devel] Error in HDF5 - Package submission - Not detected locally

Hi Tiago, The following will create a similarly sized subset of the PBMC3k dataset with the counts in-memory as a sparse matrix: pbmc3k <- TENxPBMCData::TENxPBMCData("pbmc3k") mini_pbmc3k <- pbmc3k[1:1700, 1:600] assay(mini_pbmc3k) <- as(assay(mini_pbmc3k), "dgCMatrix") Cheers, Pete On Mon, 16

Re: [Bioc-devel] Biocondutor Developers Forum

Great initiative, Mike! Could these meetings please be recorded? These will be in the middle of the night in my time zone and I'm sure others would appreciate being able to view them if they can't make the call. rOpenSci do something similar with their community calls (

Re: [Bioc-devel] any interest in a BiocMatrix core package?

ity between 'matrixStats' and 'Matrix' is basically zero(?). > I think of 'Matrix' a higher-level package. Do my comments above put > it in a different light? Or are you saying that what's in > 'matrixStats' should really have been in 'Matrix'? > > All the best, > > Henrik > > On Fri,

Re: [Bioc-devel] bsseqData

Successful pushed to both devel and release. Thanks, Nitesh! On Wed., 2 May 2018, 1:35 pm Turaga, Nitesh, <nitesh.tur...@roswellpark.org> wrote: > Try one more time please. > > I made some changes after seeing your output. > > Best, > > Nitesh > > > On M

Re: [Bioc-devel] bsseqData

SE_3_1 remotes/origin/RELEASE_3_2 remotes/origin/RELEASE_3_3 remotes/origin/RELEASE_3_4 remotes/origin/RELEASE_3_5 remotes/origin/RELEASE_3_6 remotes/origin/RELEASE_3_7 remotes/origin/master $ git log commit 5eb4c1ebc03fb1d713e873a77570744b94dc7659 Author: Peter Hickey <peter.hic...@

Re: [Bioc-devel] Virtual class for `matrix` and `DelayedArray`? (or better strategy for dealing with them both)

Tim: As the developer of DelayedMatrixStats (and enthusiastic 'canary down the coal mine' user-dev of DelayedArray) I'm obviously invested in reducing the confusion around these packages I'm going to write some blog posts-cum-vignettes-cum-F1000 around these issues over the coming weeks, with the

Re: [Bioc-devel] bsseqData

. > Val > > > > On 04/29/2018 09:37 AM, Peter Hickey wrote: > > I'm still unable to push large files after a fresh clone. I *am* able to > push smaller changes (I just tweaked the DESCRIPTION to test this). But I > get the "Error: file larger than 5 Mb" error when

Re: [Bioc-devel] bsseqData

9 Apr 2018 at 11:43 Turaga, Nitesh <nitesh.tur...@roswellpark.org> wrote: > Can you try with a fresh clone of the repo? > > Best, > > Nitesh > > > On Apr 29, 2018, at 10:21 AM, Peter Hickey <peter.hic...@gmail.com> > wrote: > > > > Nitesh

Re: [Bioc-devel] Switch to SSH protocol for git clone instructions on package landing pages?

ource code on their local machine is using the HTTPS protocol, > since they will not have access to download it via SSH ( you need > permissions to do this). > > We always advocate developers to only use SSH though. For everyone else, > HTTPS is the best option. > > Best, >

Re: [Bioc-devel] bsseqData

Nitesh, I am still getting the "Error: file larger than 5 Mb" error. On Sun, 29 Apr 2018 at 09:59 Turaga, Nitesh <nitesh.tur...@roswellpark.org> wrote: > Hi Pete, > > This should be resolved now. > > Best, > > Nitesh > > On Apr 29, 2018, at 9:50 AM, Pe

[Bioc-devel] Switch to SSH protocol for git clone instructions on package landing pages?

The one-liner on the package landing page describing how to check out a package from the git repo uses HTTPS rather than ssh, e.g.: # From https://bioconductor.org/packages/bsseq/ git clone https://git.bioconductor.org/packages/bsseq However, as a developer we should be using the SSH protocol

Re: [Bioc-devel] bsseqData

Thanks, Val. I'm getting an error about "too large files" when I try to push (see below). Is there a different workflow for pushing an experiment data package or am I doing something else wrong? bsseqData predates the svn -> git transition. Thanks, Pete $ git push origin master Counting objects:

Re: [Bioc-devel] Problem with saveHDF5SummarizedExperiment in HDF5Array package

Hi Elizabeth, Aaron and I were hit by this same error message. As a workaround, installing DelayedArray and HDF5Array from the git(hub) repo fixed the issue (https://github.com/Bioconductor/HDF5Array/issues/6). But this needs to be propagated to the versions made available via BiocLite().

Re: [Bioc-devel] problem in rbind with DelayedArray / HDF5Array package

Does `rbind(testhdf, DelayedArray(testdata))` give you what you want? On Wed, 4 Apr 2018 at 14:58 Elizabeth Purdom wrote: > Hello, > > I am trying to do a rbind a normal (in memory) matrix with a HDF5Matrix > object or DelayedArray object and I am hitting problems.

Re: [Bioc-devel] any interest in a BiocMatrix core package?

I think that's a good idea, Kylie. Pete (DelayedMatrixStats developer) On Thu., 2 Nov. 2017, 6:09 am Kasper Daniel Hansen, < kasperdanielhan...@gmail.com> wrote: > I think it makes sense. A lot of sense. Might be useful to involve Henrik > (matrixStats) as well. > > Who are the players, apart

Re: [Bioc-devel] Long-form documentation for DelayedArray?

FYI I also began a project to support an additional backend; https://github.com/PeteHaitch/matterArray. It's incomplete and may not work with the current version of DelayedArray (it's ~3 months old and I was naughtily using some internal functions of DelayedArray). I hope to return to this soon

Re: [Bioc-devel] "extra" unit tests

A partial answer if you are using the 'testthat' framework: you can use `testthat::skip_on_bioc()` to specify that a test should be skipped if it is running on the BioC build machines. The test will otherwise be run (e.g., during local development). There are some other `testthat::skip*()`

Re: [Bioc-devel] Unable to push to https://git.bioconductor.org/packages/GenomicTuples

Doh, I literally spotted that the second I hit send. Sorry for the noise and thanks! On Thu, 21 Sep 2017 at 13:55 Turaga, Nitesh <nitesh.tur...@roswellpark.org> wrote: > Hi Peter, > > If you notice, > > On Sep 21, 2017, at 1:53 PM, Peter Hickey <peter.hic...@gmail.c

[Bioc-devel] Unable to push to https://git.bioconductor.org/packages/GenomicTuples

Hi Nitesh, I'm unable to push changes to the GenomicTuples package to the BioC git host. $ git push fatal: remote error: FATAL: W any packages/GenomicTuples nobody DENIED by fallthru (or you mis-spelled the reponame) Following the FAQ (http://bioconductor.org/developers/how-to/git/faq/) I've

Re: [Bioc-devel] GitHub mirror not synced for GenomicTuples

Thanks, Martin! On 22 January 2017 at 13:10, Martin Morgan <martin.mor...@roswellpark.org> wrote: > On 01/22/2017 10:18 AM, Peter Hickey wrote: >> >> Hi, >> >> Recent changes (last few days) that successfully synced from my own GitHub >> repo to the Bi

Re: [Bioc-devel] GitHub mirror not synced for GenomicTuples

Sorry, I forgot to say this is the GenomicTuples package On 22 January 2017 at 10:18, Peter Hickey <peter.hic...@gmail.com> wrote: > Hi, > > Recent changes (last few days) that successfully synced from my own GitHub > repo to the BioC SVN and consequent builds don't seem

[Bioc-devel] GitHub mirror not synced for GenomicTuples

Hi, Recent changes (last few days) that successfully synced from my own GitHub repo to the BioC SVN and consequent builds don't seem to have propagated to the BioC GitHub mirror. Anything I should/can be doing to address this? Thanks, Pete [[alternative HTML version deleted]]

Re: [Bioc-devel] Feedback wanted on design of fixed-width Ranges class

pothetical FWRanges class in this case?) > > -Ryan > > On 11/23/16 8:01 PM, Ryan wrote: > > Is it possible to allow the width slot of IRanges to be either a > > normal vector or an Rle? > > > > > > On 11/23/16 6:18 PM, Peter Hickey wrote: > >> I've b

Re: [Bioc-devel] Feedback wanted on design of fixed-width Ranges class

But it > was fun to remember GPos, which I had forgotten. > > On Wed, Nov 23, 2016 at 6:34 PM, Vincent Carey <st...@channing.harvard.edu > > wrote: > > library(GenomicRanges) > class?GPos > > On Wed, Nov 23, 2016 at 6:18 PM, Peter Hickey <peter.hic...@gmail.com&g

[Bioc-devel] Feedback wanted on design of fixed-width Ranges class

I've been toying with the idea of a fixed/constant width Ranges subclass. The motivation comes from storing DNA methylation data at CH loci (non-CpG methylation): there are 1.1 billion CH loci in the human genome, so to store these as a GRanges object requires 2 x 1.1 billion integer vectors, one

Re: [Bioc-devel] Fast check of GenomicRanges equality to speed up cbind, SummarizedExperiment

g sequences e.g. ranges [1, 10] and > [101, 110] represent the same position on a circular sequence of > length 100 so should be considered equal. However for 'x == y' and > 'identicalVals(x, y)', they are not. Something we should address at > some point... > > Cheers, > H. &g

[Bioc-devel] Increasing MAX_BUFLENGTH in S4Vectors src/AEbufs.c

I hit an error when calling reduce() on a very big GRanges object (length = 1170402558). The error was: Error in .Call2("CompressedIRangesList_reduce", x, drop.empty.ranges, : _get_new_buflength(): MAX_BUFLENGTH reached I found MAX_BUFLENGTH is defined in S4Vectors in the file src/AEbufs.c

[Bioc-devel] Some granges() accessors broken in devel

I think this is a recent break. I'm mostly concerned because I need to use this "broken" functionality in a tutorial for BioC2016 this week and it would require changes to package internals, not the vignette, in order to fix this at my end. library(SummarizedExperiment) se <-

Re: [Bioc-devel] SVN and GitHub mirror out-of-sync

Typo - github version is 1.5.23 On Mon, 18 Apr 2016 at 09:26 Peter Hickey <peter.hic...@gmail.com> wrote: > Hi, > > The current version of GenomicTuples on the official SVN is 1.5.24 > ( > https://hedgehog.fhcrc.org/bioconductor/trunk/madman/Rpacks/GenomicTuples/DESCR

[Bioc-devel] SVN and GitHub mirror out-of-sync

Hi, The current version of GenomicTuples on the official SVN is 1.5.24 (https://hedgehog.fhcrc.org/bioconductor/trunk/madman/Rpacks/GenomicTuples/DESCRIPTION), however, the version available via the GitHub mirror is only 1.5.21

Re: [Bioc-devel] Making GenomicAlignments::readGAlignmentPairs() fail fast if given bad seqlevels in `which`

Thanks, Aaron. I implemented a similar workaround, but I think it would be nice to have in the core Bioconductor implementation. I had a quick poke around GenomicAlignments::readGAlignmentPairs(), however, but it looked like I'd have to learn a bit too much about the underlying

[Bioc-devel] Making GenomicAlignments::readGAlignmentPairs() fail fast if given bad seqlevels in `which`

Hi, GenomicAlignments::readGAlignmentPairs() can take a while to (correctly) fail if the `which` parameter contains a "bad" seqlevel. It'd be great if it failed early in the following scenario (just experienced). An example BAM is available from

Re: [Bioc-devel] Making GenomicAlignments::readGAlignmentPairs() fail fast if given bad seqlevels in `which`

Wonderful. Thanks, Martin > in svn at 1.23.5, and in Bioc-devel hopefully after tonight's build. > > Martin ___ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel

Re: [Bioc-devel] Behaviour of rbind/cbind on assays slot of SummarizedExperiment with multidimensional assays

Hi Pete, > > On 03/02/2016 12:42 PM, Peter Hickey wrote: > > This is mostly directed to Herve and/or Martin, but I'd be interested > > in other's input too. > > > > The SummarizedExperiment package defines rbind,Assays-method and > > cbind,Assay

[Bioc-devel] Behaviour of rbind/cbind on assays slot of SummarizedExperiment with multidimensional assays

This is mostly directed to Herve and/or Martin, but I'd be interested in other's input too. The SummarizedExperiment package defines rbind,Assays-method and cbind,Assays-method that are called when rbind() or cbind() is called on a SummarizedExperiment object. In the case of two-dimensional assay

[Bioc-devel] dimnames of multidimensional assays in SummarizedExperiment

The assays slot in a SummarizedExperiment object supports elements with up to 4 dimensions [*] library(SummarizedExperiment) makeSE <- function(n) { assay <- array(1:2^n, dim = rep(2, n), dimnames = split(letters[1:(2 * n)], seq_len(n)))

Re: [Bioc-devel] Use of Matrix inside SummarizedExperiment

Thanks, Hervé! On 26/01/2016, Hervé Pagès <hpa...@fredhutch.org> wrote: > Hi Pete, > > On 01/25/2016 12:32 PM, Peter Hickey wrote: >> The Matrix virtual class in the Matrix package seems to mostly work as >> an assays element in a SummarizedExperiment. This is es

Re: [Bioc-devel] do SummarizedExperiments really need colnames?

While on the topic of SummarizedExperiment colnames, the circumstances in which these are stripped from the assays and overridden by colData is confusing to me, particularly case 2 below (a warning in case 3 might be useful too). > m1 <- matrix(1:10, ncol = 2) > m2 <- m1 > colnames(m2) <- c("A",

Re: [Bioc-devel] segfault when using RleList in DataFrames

Hi Leonard, I'm seeing what I think is a related problem in the devel branch. I think it derives from some issue with List-based classes. E.g, a simplified version of your example errors for me (although without segfault): > library(IRanges) # snip - this produces a possibly related warning on

Re: [Bioc-devel] is.unsorted method for GRanges objects

passing S4Vectors:::decodeRle(seqnames(x)), >> start(x), with(x), and S4Vectors:::decodeRle(strand(x)) to the .Call >> entry point). >> >> I'll take your patch if you want to work on this or I can add this >> to GenomicRanges, let me know. We should probably take this

Re: [Bioc-devel] is.unsorted method for GRanges objects

al question of whether GenomicRanges >>> should >>> have an anyNA method that returns FALSE (and similarly an is.na() >>> method), >>> although we have never defined the concept of a "missing range". >>> >>> Michael >&

[Bioc-devel] is.unsorted method for GRanges objects

Hi all, I sometimes want to test whether a GRanges object (or some object with a GRanges slot, e.g., a SummarizedExperiment object) is (un)sorted. There is no is.unsorted,GRanges-method or, rather, it defers to is.unsorted,ANY-method. I'm unsure that deferring to the is.unsorted,ANY-method is

[Bioc-devel] Help using Git with Bioconductor SVN repositories

I used to use the git-svn bridge for my GenomicTuples package, which I develop on GitHub. Several months ago I attempted to switch to the new method described at http://bioconductor.org/developers/how-to/git-mirrors/ but made a complete mess of it. This wasn't so important at the time since I

[Bioc-devel] A method for combining SummarizedExperiment objects

I often find myself with multiple `SE` objects (I'm using `SE` as a shorthand for the `SummarizedExperiment0` and `RangedSummarizedExeriment` classes), each with different samples but possibly non-overlapping features/ranges. Currently, it is difficult to combine these objects; `rbind()` can only

Re: [Bioc-devel] A method for combining SummarizedExperiment objects

Sorry, the URL may have been mangled. It's https://gist.github.com/PeteHaitch/8993b096cfa7ccd08c13 <https://gist.github.com/PeteHaitch/8993b096cfa7ccd08c13.> On Thu, 15 Oct 2015 at 12:52 Peter Hickey <peter.hic...@gmail.com> wrote: > I often find myself with multiple `SE` objects

[Bioc-devel] Minor (impossible to trigger?) bug in assay, SummarizedExperiment0, character-method

See https://github.com/Bioconductor-mirror/SummarizedExperiment/blob/744eea36e9f8ee4daea00baa7a1d9eea68d957ca/R/SummarizedExperiment0-class.R#L210 I think it should be 'i = assayNames(x)[1]'. I say it is impossible to trigger because I don't think this method is ever called since if 'i' is

Re: [Bioc-devel] Adding a lengths() method to List class

se [[ internally. >>> >>> Do you know of any reason why lengths() doesn't do this? >>> >>> Thanks, >>> H. >>> >>> >>> On 09/28/2015 09:51 PM, Michael Lawrence wrote: >>> >>> That is the plan. Note that we a

Re: [Bioc-devel] Missed change in S4Vectors

you're seeing. I think that if you just re-install S4Vectors locally (without making the change you proposed) the issue will go away. Hopefully... H. On 08/10/2015 06:46 PM, Peter Hickey wrote: Sorry, that should say once I made the proposed change to S4Vectors, not IRanges. On Tue

Re: [Bioc-devel] Missed change in S4Vectors

not be necessary (and doing so will actually trigger a note from R CMD check). Can you provide more details on why you need this? Thanks, H. On 08/09/2015 09:16 PM, Peter Hickey wrote: Hi Hervé, I was having trouble with some devel code of mine and tracked it down to some recent updates moving

Re: [Bioc-devel] Missed change in S4Vectors

Sorry, that should say once I made the proposed change to S4Vectors, not IRanges. On Tue, 11 Aug 2015 8:51 am Peter Hickey peter.hic...@gmail.com wrote: Hi Hervé, Hmm, sorry I may have misdiagnosed my problem. I was having problems with some code in the bsseq vignette. The following

Re: [Bioc-devel] Google hangout on Wed December 10th for new package authors

Hi Marc, Will a recording be made available? This sounds quite useful, but not quite staying up until 2am Australian time useful :) Thanks, Pete Message: 5 Date: Tue, 2 Dec 2014 15:08:08 -0800 From: Marc Carlson mcarl...@fredhutch.org To: bioc-devel bioc-de...@stat.math.ethz.ch Subject:

Re: [Bioc-devel] Changes to Hits class in devel branch affecting distanceToNearest method

with the behavior of distanceToNearest method for GRanges objects. The major issue being that it sometimes returns a Hits object with NAs in it. Val will address this in the next few days. Cheers, H. On 11/05/2014 06:21 PM, Peter Hickey wrote: This message may be a bit premature or redundant

[Bioc-devel] Bug in GenomicRanges:::compare

Hi Martin, The last element of 'x' is never accessed in a call to the internal function GenomicRanges:::.compare when 'GenomicRanges = TRUE'. The attached patch fixes this. Cheers, Pete === --- R/SummarizedExperiment-class.R

[Bioc-devel] should genome() be so complicated?/add genome report to GRanges show method

://stat.ethz.ch/mailman/listinfo/bioc-devel Peter Hickey, PhD Student/Research Assistant, Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic 3052, Australia. Ph: +613 9345 2324 hic...@wehi.edu.au http://www.wehi.edu.au

Re: [Bioc-devel] should genome() be so complicated?/add genome report to GRanges show method

/2014 02:28 PM, Peter Hickey wrote: Just a vote for still allowing for multiple genomes in a Seqinfo object (in a GRanges object). My use case is in bisulfite-sequencing experiments where there is often a spike-in of a lambda phage genome along with the genome of interest (human or mouse

Re: [Bioc-devel] Valid classes for extraColumnSlots

On 29/08/2014, at 1:18 PM, Michael Lawrence lawrence.mich...@gene.com wrote: Added to S4Vectors. Thanks! On Thu, Aug 28, 2014 at 5:04 PM, Peter Hickey hic...@wehi.edu.au wrote: Thanks, Michael. Do you think there's a general use case for a replaceROWs, NULL method or shall I just specify

Re: [Bioc-devel] Valid classes for extraColumnSlots

, 2014 at 5:13 PM, Peter Hickey hic...@wehi.edu.au wrote: Hi Michael, Thanks for your patience. Here is a self-contained example with comments https://gist.github.com/PeteHaitch/fdb66d360446ff96ed4b Thanks, Pete On 27/08/2014, at 1:43 AM, Michael Lawrence lawrence.mich...@gene.com wrote

Re: [Bioc-devel] Valid classes for extraColumnSlots

- Original Message -From: Michael Lawrence lawrence.mich...@gene.comTo: Peter Hickey hic...@wehi.edu.auCc: bioc-devel@r-project.orgSent: Tue, 26 Aug 2014 13:35:35 +1000 (EST)Subject: Re: [Bioc-devel] Valid classes for extraColumnSlots Hi Peter, Some code would help here. I'm not sure

Re: [Bioc-devel] Valid classes for extraColumnSlots

it to reproduce the problem and fix things. Thanks, Michael On Tue, Aug 26, 2014 at 4:25 AM, Peter Hickey hic...@wehi.edu.au wrote: Hi Michael, Sorry for my misunderstanding. Here is some code describing the class https://github.com/PeteHaitch/GenomicTuples/blob/master/R/GTuples

[Bioc-devel] seqnames of SNPlocs.*

Bioconductor data sources. Thanks, Pete Peter Hickey, PhD Student/Research Assistant, Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic 3052, Australia. Ph: +613 9345 2324 hic...@wehi.edu.au http

Re: [Bioc-devel] seqnames of SNPlocs.*

, but there is seqnamesStyle infrastructure in GenomeInfoDb that may help. On Tue, Jun 17, 2014 at 8:17 PM, Peter Hickey hic...@wehi.edu.au wrote: Is there a reason why the seqnames of SNPlocs.Hsapiens.dbSNP.20120608 (and possibly the other SNPlocs.*) use the prefix ch instead of chr? E.g. ch1 instead of chr1

Re: [Bioc-devel] My == method breaks existing == method for signature c(Rle, vector')

-- On 28/05/2014, at 3:23 AM, Hervé Pagès hpa...@fhcrc.org wrote: Hi Peter, On 05/26/2014 04:37 PM, Peter Hickey wrote: Thanks for the suggested work-around, Martin. In order to define the method on the group

Re: [Bioc-devel] My == method breaks existing == method for signature c(Rle, vector')

'=', '!=', '' and '' for free, which is great!). Unfortunately, as you can see, the MTuples '==' method breaks '==' for other signatures. Hope that wasn't too tangential. Cheers, Pete On 27/05/2014, at 2:44 AM, Martin Morgan mtmor...@fhcrc.org wrote: On 05/25/2014 09:39 PM, Peter Hickey wrote

[Bioc-devel] My == method breaks existing == method for signature c(Rle, vector')

-- Peter Hickey, PhD Student/Research Assistant, Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic 3052, Australia. Ph: +613 9345 2324 hic

[Bioc-devel] Restrictions on findOverlaps parameters with SummarizedExperiment objects

subject target Vector SummarizedExperiment defined Vector SummarizedExperiment Peter Hickey, PhD Student/Research Assistant, Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic 3052

Re: [Bioc-devel] Restrictions on findOverlaps parameters with SummarizedExperiment objects

Thanks for the explanation and the update, Martin. Cheers, Pete - Original Message - From: Martin Morgan mtmor...@fhcrc.org To: Peter Hickey hic...@wehi.edu.au, bioc-devel@r-project.org Sent: Sat, 12 Apr 2014 06:45:46 +1000 (EST) Subject: Re: [Bioc-devel] Restrictions on findOverlaps

Re: [Bioc-devel] Help in designing class based on SummarizedExperiment

Apologies for the bump, but is anyone able to help me on this? Or are these questions more appropriate for the general Bioconductor mailing list rather than Bioc-Devel? Many thanks, Pete - Original Message - Date: Mon, 10 Feb 2014 13:20:47 +1100 From: Peter Hickey hic...@wehi.edu.au

[Bioc-devel] Help in designing class based on SummarizedExperiment

of the CoMeth class are appreciated. Thanks, Pete Peter Hickey, PhD Student/Research Assistant, Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic 3052, Australia. Ph: +613 9345 2324 hic...@wehi.edu.au http