[ccp4bb] 71st Annual Pittsburgh Diffraction Conference

2013-07-18 Thread Edward Snell
Dear All, The 71st Annual Pittsburgh Diffraction Conference will be being held at the Hauptman-Woodward Medical Research Institute from the evening of the 18th of September to the afternoon of the 20th. Preliminary details are at http://www.pittdifsoc.org/PDC_2013/pittsburgh_diffraction_flyer.p

[ccp4bb] Of topic, trying to identify a reference for multiple crystal data collection

2013-07-18 Thread Edward Snell
Dear All, On a beamline visit I came across a photocopy of a table comprising point groups, number of random images and the percentage completeness that resulted. The Table is labeled 17.1 and the table legend starts with the text "Data from randomly oriented images. The figures shown are the p

Re: [ccp4bb] Dose anyone see this ligand before?

2013-07-18 Thread Wei Feng
Dear Dale Tronrud, Thanks for your advise. Initially, i focused on the shape of the density. As you suggest, i checked all possible biological molecules and common additives used in purification and crystallization. I found that the structure of bis-tris-propane is similar to the target density.

[ccp4bb] PhD student position in Structural Biology at University of Bayreuth

2013-07-18 Thread Michael Weyand
**We are currently looking for a highly motivated Ph.D. student for our laboratory at the Dept. of Biochemistry at University Bayreuth, Germany. Our work involves biochemical and structural studies on cellular signalling systems with relevance to aging mechanisms or disease. The PhD project will co

[ccp4bb] post-doctoral in membrane protein structural biology

2013-07-18 Thread Pascal Egea
We are seeking a post-doctoral researcher to join my research group at UCLA. The lab focuses on the structural studies of challenging targets: membrane protein complexes and channels from eukaryotes (yeast and several parasites) and seeks to characterize their architecture and molecular mechani

[ccp4bb] Off-topic post: Inverted DNA repeats vs direct repeats

2013-07-18 Thread Raji Edayathumangalam
Hi Everyone, One of the proteins I work with is a transcription factor that binds to two direct repeats in its cognate binding site. That my protein binds direct repeats is unlike most other members of its family that bind to inverted repeats. One of the reviewers of a paper that my colleagues and

Re: [ccp4bb] TLS refinement refmac

2013-07-18 Thread Eleanor Dodson
Well - most refinement procedures output the Fobs and the Fcalc on the same (more-or-less) absolute scale.. After data processing the observations are on a more or less arbitrary scale, so that seems sensible. It gets more problematic when you start correcting for anisotropy.. Eleanor On 17 J

[ccp4bb] CCP4 Newsletter 49

2013-07-18 Thread Karen McIntyre
Dear BB members The latest issue of the CCP4 newsletter is now available at http://www.ccp4.ac.uk/newsletters.php . Regards Karen McIntyre Scientific Computing Department - CCP4 R92 1.22 RCaH Science & Technology Facilities Council Rutherford Appleton Laboratory Harwell Science & Innovation Ca

[ccp4bb] PhD studentship in Biological Image Analysis

2013-07-18 Thread Alun Ashton
(Full details at http://www.nottingham.ac.uk/jobs/currentvacancies/ref/SCI1278) Applications are invited for a fully-funded PhD studentship to be held jointly at the School of Computer Science, University of Nottingham and The Diamond Light Source, the UK's national synchrotron facility at Harwe