*Research technician position *
is available in the research *group of Kristina Djinovic-Carugo* in the
Department for Structural and Computational Biology, Max. F. Perutz
Laboratories of the University of Vienna, Austria. The main area of the
group research is structural biology of F-actin bas
PanDDA tries to arrive at an objective score metric for presence:
http://biorxiv.org/content/early/2016/09/05/073411
But in the end, you still have to apply all the scientific rigour that
Bernard mentions.
On 23/02/2017 13:56, Mohamed Noor wrote:
Dear all
I think I have a ligand (substrate
Dear Eleanor,
sorry for the late reply. I found a similar case (id: 2OEF, Cys 92). I
mutated the Cys to Ser, but it did not change anything (xtal conditions and
quality remained the same). In solution the protein is a monomer.
However, adding 1 mM DTT resulted in a significant increase in crystal
At the risk of being redundant, I can only restate what I and many others
have posted before:
No simple answer or single universal statistic for your justified question
or concern exists. The crucial question to ask first is what hypothesis or
claims is your (ligand) model at that specific locatio
Well - I certainly would do more refinement - if something is bound there
will be other changes in solvent etc.
then search the difference map for peaks/ find ligand etc, and see what it
shows..
If your original model and this one are isomorphous you can also check the
Fobs-lig -Fobs-nolig Phi-no
Dear All,
The group of Dr. Marcin Nowotny at the International Institute of Molecular and
Cell Biology (IIMCB) in Warsaw, Poland is seeking candidates for postdoctoral
fellows and PhD students. The fellows will work on protein complexes involved
in retrotransposition and reverse transcription u
Dear all
I think I have a ligand (substrate) placed in the active site of my model
correctly. The CC is 0.785, B factor of 60 A^2 which is roughly similar to the
neighboring residues and there was no ligand in my search model*. The data
extends to 2.2 A, although I think I can get something hig
Dear all,
Two postdoc fellowships are available in my lab at Umeå University,
Sweden. The projects aim to decipher the molecular basis of human RNA
virus replication using in vitro membrane reconstitution and cryo-EM
(tomography of cells and single particle analysis).
We are looking for highl
Please mark your calendar:
The next MX-proposal application deadline: March 01, 2017 is approaching
http://www.helmholtz-berlin.de/user/beamtime/proposals/index_en.html
Hereby we would like to invite the submission of new proposals for
MX-beamtime at the HZB-MX beamlines for the next beam time p
